Mouse IL-31 Biotinylated Antibody

Name: Mouse IL-31 Biotinylated Antibody
Brand: R&D Systems
SKU: BAF3028
Rating: 5 (1 reviews)

Catalog #: BAF3028
1 Citation 1 Review Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
BAF3028

All IL-31 Antibodies

Product Details

Citations (1)

FAQs

Supplemental Products

Reviews (1)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IL-31 Biotinylated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL-31 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human IL-31 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse IL-31
Thr24-Cys163
Accession # Q6EAL8

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse IL‑31

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-31

IL-31 is a 25 kDa, unique member of the short chain group of alpha -helical cytokines. It is produced by activated T cells, particularly the Th2 CD4⁺ phenotype. Mouse IL‑31 cDNA encodes a 163 amino acid (aa) precursor that contains a 22 aa signal sequence and a 141 aa mature region. IL-31 signals through a receptor complex composed of IL-31 receptor A and Oncostatin M receptor. Mature mouse IL‑31 shares 25% aa sequence identity with mature human IL-31 and 44% aa sequence identity with a rat IL-31-like protein.

Long Name

Interleukin 31

Entrez Gene IDs

386653 (Human); 76399 (Mouse)

Alternate Names

IL31; IL-31; IL-31interleukin-31; interleukin 31

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse IL-31 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity
Authors: A Takamori, A Nambu, K Sato, S Yamaguchi, K Matsuda, T Numata, T Sugawara, T Yoshizaki, K Arae, H Morita, K Matsumoto, K Sudo, K Okumura, J Kitaura, H Matsuda, S Nakae
Sci Rep, 2018-04-27;8(1):6639.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC