Mouse Luminex® Discovery Assay

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Mouse Luminex Assay
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Citations (174)
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Mouse Luminex® Discovery Assay Summary

Assay Type Magnetic bead-based multiplex assay for the Luminex® platform
Format 1 x 96-well microplate and Magnetic antibody-coated beads
Species Mouse
Analytes Detected Please see analyte list in assay customization tool below.
Performance Validation Luminex Assays are validated for use with cell culture supernatants, plasma and serum. All Luminex assays are tested for sensitivity, intra-assay precision, inter-assay precision and to ensure assay linearity for validated sample types. Antibody pairs are selected and tested to confirm the parallel detection of natural and recombinant standard protein and to ensure the accurate determination of target analytes within biological samples. Assays for each target analyte are screened against all target analytes to confirm low antibody cross-reactivity.

The mouse discovery Luminex Assay is also validated for use with tissue lysates.

Make your selections below to configure your assay

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Assays

Below are kits that are available based on your selections. These selections may be further customized before adding to the cart or emailing the configuration to your purchasing department or local distributor to place your order. Selected analytes may be included in more than one High Performance Assay. All assay options are displayed.

If you run into bead region incompatibilities, send your Luminex code to our team and find out more.

How would you like these analytes mixed?

Premixed
User Mixed
Please select at least one mixing option to see the kits.

Would you like to split based on dilution?

Do not split
Split based on serum
Split based on plasma
Split based on cell culture supernates

Not finding your analyte of interest? View our complete Luminex offering in the full version of our Luminex Assay Customization Tool. We also offer Custom Luminex Services.

Product Features

Magnetic Luminex Assays are the most flexible bead-based multiplex assays that we offer. They allow up to 50 user-defined target analytes to be simultaneously profiled using cell culture supernates, serum, or plasma samples.

  • Simultaneously profile up to 50 analytes of your choice in one sample
  • Choose from a wide menu of analytes, including many unique analytes
  • Requires a small sample volume (<50 µL)
  • Run your assay in just 3-4 hours
  • Mass-calibrated standards for consistent results with every new lot of material
  • Enough reagents for one 96-well plate
  • Quick turn-around time: Kits are typically shipped within 5-10 days of ordering.*

Please allow additional time for international orders.

Kit Components
  • Premixed cocktail of antibody-coated Magnetic beads
  • Premixed cocktail of biotinylated detection antibody
  • Standard Cocktail(s)
  • Bead Diluent
  • Biotin Antibody Diluent
  • Standard/Sample Diluent
  • Wash Buffer
  • Streptavidin-PE
  • One flat-bottom 96-well Microplate
  • Foil Plate Sealers (4)
  • Mixing Bottle
  • Certificate of Analysis**

**A standard curve must be generated each time an assay is run, utilizing values from the Certificate of Analysis provided with each Luminex Assay.

Which Luminex Assay is right for me?

Assays for the Luminex platform are offered as High Performance Assays or Assays. The Luminex High Performance Assays are fully validated panels with a focused selection of analytes. They are available in We Mix, You Mix, and Predetermined formats. The Luminex Assays allows for the maximum number of analytes in a multiplex and is supplied as a premixed kit. View a table comparing the features and benefits of these bead-based multiplex assays.

Product Datasheets

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Product Specific Notices
Luminex® is a registered trademark of Luminex Corporation.

Citations for Mouse Luminex® Discovery Assay

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

174 Citations: Showing 1 - 10
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  1. Bone marrow monocytes sustain NK cell-poiesis during non-alcoholic steatohepatitis
    Authors: Bourayou, E;Perchet, T;Meunier, S;Bouvier, H;Mailhe, MP;Melanitou, E;Cumano, A;Golub, R;
    Cell reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Effects of poly (ADP-ribose) polymerase inhibitor treatment on the repair process of ischemic acute kidney injury
    Authors: Jeon, J;Lee, K;Jang, HR;Yang, KE;Lee, CJ;Ahn, H;Park, WY;Lee, JE;Kwon, GY;Kim, YG;Huh, W;
    Scientific reports
    Species: Mouse
    Sample Types: Tissue Homogenates
  3. Promotion of transcription factor EB-dependent autophagic process by curcumin alleviates arsenic-caused lung oxidative stress and inflammation in mice
    Authors: Xu, G;Chen, H;Cong, Z;Wang, R;Li, X;Xie, Y;Wang, Y;Li, B;
    The Journal of nutritional biochemistry
    Species: Mouse
    Sample Types: Serum
  4. EpCAM-targeting CAR-T cell immunotherapy is safe and efficacious for epithelial tumors
    Authors: Li, D;Guo, X;Yang, K;Yang, Y;Zhou, W;Huang, Y;Liang, X;Su, J;Jiang, L;Li, J;Fu, M;He, H;Yang, J;Shi, H;Yang, H;Tong, A;Chen, N;Hu, J;Xu, Q;Wei, YQ;Wang, W;
    Science advances
    Species: Mouse
    Sample Types: Serum
  5. Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections
    Authors: Abberger, H;Hose, M;Ninnemann, A;Menne, C;Eilbrecht, M;Lang, KS;Matuschewski, K;Geffers, R;Herz, J;Buer, J;Westendorf, AM;Hansen, W;
    PLoS pathogens
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. Comparison of the Immunogenicity and Efficacy of rBCG-EPCP009, BCG Prime-EPCP009 Booster, and EPCP009 Protein Regimens as Tuberculosis Vaccine Candidates
    Authors: Wang, R;Fan, X;Xu, D;Li, M;Zhao, X;Cao, B;Qian, C;Yu, J;Fang, D;Gu, Y;Wan, K;Liu, H;
    Vaccines
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. Mesenchymal Stromal Cells Primed by Toll-like Receptors 3 and 4 Enhanced Anti-Inflammatory Effects against LPS-Induced Macrophages via Extracellular Vesicles
    Authors: Hwang, S;Sung, DK;Kim, YE;Yang, M;Ahn, SY;Sung, SI;Chang, YS;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection
    Authors: Griffith, JW;Faustino, LD;Cottrell, VI;Nepal, K;Hariri, LP;Chiu, RS;Jones, MC;Julé, A;Gabay, C;Luster, AD;
    Nature immunology
    Species: Mouse
    Sample Types: BALF
  9. Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge
    Authors: Weaver, KL;Bitzer, GJ;Wolf, MA;Pyles, GM;DeJong, MA;Dublin, SR;Huckaby, AB;Gutierrez, MP;Hall, JM;Wong, TY;Warden, M;Petty, JE;Witt, WT;Cunningham, C;Sen-Kilic, E;Damron, FH;Barbier, M;
    PloS one
    Species: Mouse
    Sample Types: Tissue Homogenates
  10. Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer
    Authors: Hughson, AL;Hannon, G;Salama, NA;Vrooman, TG;Stockwell, CA;Mills, BN;Garrett-Larsen, J;Qiu, H;Katerji, R;Benoodt, L;Johnston, CJ;Murphy, JD;Kruger, E;Ye, J;Gavras, NW;Keeley, DC;Qin, SS;Lesch, ML;Muhitch, JB;Love, TMT;Calvi, LM;Lord, EM;Luheshi, N;Elyes, J;Linehan, DC;Gerber, SA;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Tissue Homogenates
  11. Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck
    Authors: Zlygosteva, O;Juvkam, IS;Aass, HCD;Galtung, HK;Søland, TM;Malinen, E;Edin, NFJ;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Saliva, Serum
  12. Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer's disease and brain aging
    Authors: Corraliza-Gomez, M;Bermejo, T;Lilue, J;Rodriguez-Iglesias, N;Valero, J;Cozar-Castellano, I;Arranz, E;Sanchez, D;Ganfornina, MD;
    Journal of neuroinflammation
    Species: Transgenic Mouse, Mouse
    Sample Types: Cell Culture Supernates
  13. Epigallocatechin Gallate-Modified Silver Nanoparticles Show Antiviral Activity against Herpes Simplex Type 1 and 2
    Authors: Krzyzowska, M;Janicka, M;Chodkowski, M;Patrycy, M;Obuch-Woszczaty?ska, O;Tomaszewska, E;Ranoszek-Soliwoda, K;Celichowski, G;Grobelny, J;
    Viruses
    Species: Mouse
    Sample Types: Vaginal Lavage Fluid
  14. Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation
    Authors: Markezana, A;Paldor, M;Liao, H;Ahmed, M;Zorde-Khvalevsky, E;Rozenblum, N;Stechele, M;Salvermoser, L;Laville, F;Goldmann, S;Rosenberg, N;Andrasina, T;Ricke, J;Galun, E;Goldberg, SN;
    Scientific reports
    Species: Mouse
    Sample Types: Plasma
  15. Calorie restriction outperforms bariatric surgery in a murine model of obesity and triple-negative breast cancer
    Authors: Camp, K;Coleman, MF;McFarlane, T;Doerstling, SS;Khatib, SA;Rezeli, ET;Lewis, AG;Pfeil, AJ;Smith, LA;Bowers, LW;Fouladi, F;Gong, W;Glenny, EM;Parker, JS;Milne, GL;Carroll, IM;Fodor, AA;Seeley, RJ;Hursting, SD;
    JCI insight
    Species: Mouse
    Sample Types: Serum
  16. Regulation of IGF1R by MicroRNA-15b Contributes to the Anticancer Effects of Calorie Restriction in a Murine C3-TAg Model of Triple-Negative Breast Cancer
    Authors: Bustamante-Marin, X;Devlin, KL;McDonell, SB;Dave, O;Merlino, JL;Grindstaff, EJ;Ho, AN;Rezeli, ET;Coleman, MF;Hursting, SD;
    Cancers
    Species: Mouse
    Sample Types: Serum
  17. miR-378 influences muscle satellite cells and enhances adipogenic potential of fibro-adipogenic progenitors but does not affect muscle regeneration in the glycerol-induced injury model
    Authors: Mucha, O;Podkalicka, P;?ukowska, M;Po?piech, E;Dulak, J;?oboda, A;
    Scientific reports
    Species: Mouse
    Sample Types: Tissue Homogenates
  18. Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity
    Authors: Earhart, AP;Karasseva, NG;Storey, KM;Olthoff, B;Sarker, MB;Laffey, KG;Lange, MJ;Rector, RS;Schulz, LC;Gil, D;Neuhauser, CM;Schrum, AG;
    Cell reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-?B pathway in Crohn's disease
    Authors: Zhou, L;Zhu, L;Wu, X;Hu, S;Zhang, S;Ning, M;Yu, J;Chen, M;
    BMC medicine
    Species: Mouse
    Sample Types: Serum
  20. Expression conditions and characterization of a novelly-constructed lipoprotein intended as a vaccine to prevent human Haemophilus influenzae infections
    Authors: Kaur, R;Mangiafesto, J;Pryharski, K;Rasam, S;Zagursky, R;Pichichero, M;
    The Journal of biological chemistry
    Species: Mouse
    Sample Types: Serum
  21. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
    Authors: Zhang, T;Xu, D;Liu, J;Wang, M;Duan, LJ;Liu, M;Meng, H;Zhuang, Y;Wang, H;Wang, Y;Lv, M;Zhang, Z;Hu, J;Shi, L;Guo, R;Xie, X;Liu, H;Erickson, E;Wang, Y;Yu, W;Dang, F;Guan, D;Jiang, C;Dai, X;Inuzuka, H;Yan, P;Wang, J;Babuta, M;Lian, G;Tu, Z;Miao, J;Szabo, G;Fong, GH;Karnoub, AE;Lee, YR;Pan, L;Kaelin, WG;Yuan, J;Wei, W;
    Nature cell biology
    Species: Mouse
    Sample Types: Serum
  22. Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells
    Authors: Jadi, PK;Dave, A;Issa, R;Tabbasum, K;Okurowska, K;Samarth, A;Urwin, L;Green, LR;Partridge, LJ;MacNeil, S;Garg, P;Monk, PN;Roy, S;
    The ocular surface
    Species: Mouse
    Sample Types: Tissue Homogenates
  23. Effects of R-salbutamol on the inflammatory response and acute lung injury in endotoxemic mice
    Authors: Beng, H;Hu, J;Wang, S;Liang, X;Qin, H;Tan, W;
    International immunopharmacology
    Species: Mouse
    Sample Types: Serum
  24. IL-6 and TGF-?-Secreting Adoptively-Transferred Murine Mesenchymal Stromal Cells Accelerate Healing of Psoriasis-like Skin Inflammation and Upregulate IL-17A and TGF-?
    Authors: Cuesta-Gomez, N;Medina-Ruiz, L;Graham, GJ;Campbell, JDM;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  25. Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle
    Authors: Nasir, NJM;Heemskerk, H;Jenkins, J;Hamadee, NH;Bunte, R;Tucker-Kellogg, L;
    eLife
    Species: Mouse
    Sample Types: Tissue Homogenates
  26. MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses
    Authors: Heuberger, CE;Janney, A;Ilott, N;Bertocchi, A;Pott, S;Gu, Y;Pohin, M;Friedrich, M;Mann, EH;Pearson, C;Powrie, FM;Pott, J;Thornton, E;Maloy, KJ;
    Mucosal immunology
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates
  27. Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology
    Authors: Gullotta, GS;De Feo, D;Friebel, E;Semerano, A;Scotti, GM;Bergamaschi, A;Butti, E;Brambilla, E;Genchi, A;Capotondo, A;Gallizioli, M;Coviello, S;Piccoli, M;Vigo, T;Della Valle, P;Ronchi, P;Comi, G;D'Angelo, A;Maugeri, N;Roveri, L;Uccelli, A;Becher, B;Martino, G;Bacigaluppi, M;
    Nature immunology
    Species: Mouse
    Sample Types: Plasma
  28. Inhaled pan-phosphodiesterase inhibitors ameliorate ovalbumin-induced airway inflammation and remodeling in murine model of allergic asthma
    Authors: W�jcik-Pszczo?a, K;Pociecha, K;Ch?o?-Rzepa, G;Zadro?na, M;Nowak, B;Plutecka, H;Koczurkiewicz-Adamczyk, P;Przejczowska-Pomierny, K;P?kala, E;Gosens, R;Wyska, E;
    International immunopharmacology
    Species: Mouse
    Sample Types: BALF
  29. Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction
    Authors: D Sawaki, Y Zhang, A Mohamadi, M Pini, Z Mezdari, L Lipskaia, S Naushad, L Lamendour, DM Altintas, M Breau, H Liang, M Halfaoui, T Delmont, M Surenaud, D Rousseau, T Yoshimitsu, F Louache, S Adnot, C Henegar, P Gual, G Czibik, G Derumeaux
    JCI Insight, 2023-04-24;8(8):.
    Species: Mouse
    Sample Types: Plasma
  30. The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation
    Authors: IA von Mücke-, J Martin, M Uhr, C Ries, JM Deussing
    Frontiers in Pharmacology, 2023-04-10;14(0):1148190.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  31. A Multistage Antigen Complex Epera013 Promotes Efficient and Comprehensive Immune Responses in BALB/c Mice
    Authors: C Qian, X Fan, R Wang, B Cao, J Yu, X Luan, G Li, Y Jiang, M Li, X Zhao, D Fang, K Wan, H Liu, Y Lou
    Vaccines, 2023-03-07;11(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  32. Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages
    Authors: C Yi, J Liu, W Deng, C Luo, J Qi, M Chen, H Xu
    Journal of Neuroinflammation, 2023-02-23;20(1):45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  33. Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population
    Authors: JD Morel, MB Sleiman, TY Li, G von Alvens, AM Bachmann, D Hofer, E Broeckx, JY Ma, V Carreira, T Chen, N Azhar, RA Gonzalez-V, M Breyer, D Reilly, S Mullican, J Auwerx
    JCI Insight, 2023-02-08;8(3):.
    Species: Mouse
    Sample Types: Plasma
  34. Mono-ADP-ribosyltransferase 1 ( Artc1 )-deficiency decreases tumorigenesis, increases inflammation, decreases cardiac contractility, and reduces survival
    Authors: H Ishiwata-E, J Kato, H Oda, J Sun, ZX Yu, C Liu, DA Springer, P Dagur, MJ Lizak, E Murphy, J Moss
    bioRxiv : the preprint server for biology, 2023-02-06;0(0):.
    Species: Mouse
    Sample Types: Plasma
  35. Akkermansia muciniphila Alleviates Persistent Inflammation, Immunosuppression, and Catabolism Syndrome in Mice
    Authors: Y Xu, J Duan, D Wang, J Liu, X Chen, XY Qin, W Yu
    Metabolites, 2023-01-28;13(2):.
    Species: Mouse
    Sample Types: Serum
  36. Timing and cell specificity of senescence drives postnatal lung development and injury
    Authors: H Yao, J Wallace, AL Peterson, A Scaffa, S Rizal, K Hegarty, H Maeda, JL Chang, N Oulhen, JA Kreiling, KE Huntington, ME De Paepe, G Barbosa, PA Dennery
    Nature Communications, 2023-01-17;14(1):273.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  37. Pro-Inflammatory and Cytotoxic Effects of Polystyrene Microplastics on Human and Murine Intestinal Cell Lines
    Authors: V Mattioda, V Benedetti, C Tessarolo, F Oberto, A Favole, M Gallo, W Martelli, MI Crescio, E Berio, L Masoero, A Benedetto, M Pezzolato, E Bozzetta, C Grattarola, C Casalone, C Corona, F Giorda
    Biomolecules, 2023-01-10;13(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  38. Nonsteroidal anti-inflammatory drugs (NSAIDs) and nucleotide analog GS-441524 conjugates with potent in vivo efficacy against coronaviruses
    Authors: Q Zhou, Y Luo, Y Zhu, Q Chen, J Qiu, F Cong, Y Li, X Zhang
    European Journal of Medicinal Chemistry, 2023-01-10;249(0):115113.
    Species: Mouse
    Sample Types: Tissue Homogenates
  39. Single-Cell Transcriptomic Profiles of Lung Pre-Metastatic Niche Reveal Neutrophil and Lymphatic Endothelial Cell Roles in Breast Cancer
    Authors: YC Huang, CY Chang, YY Wu, KL Wu, YM Tsai, HC Lee, EM Tsai, YL Hsu
    Cancers, 2022-12-28;15(1):.
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates
  40. Involvement of miRNA-34a regulated Kr�ppel-like factor 4 expression in hyperoxia-induced senescence in lung epithelial cells
    Authors: H Maeda, H Yao, H Go, KE Huntington, ME De Paepe, PA Dennery
    Respiratory Research, 2022-12-10;23(1):340.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. p21 induces a senescence program and skeletal muscle dysfunction
    Authors: DA Englund, A Jolliffe, Z Aversa, X Zhang, I Sturmlechn, AE Sakamoto, JD Zeidler, GM Warner, C McNinch, TA White, EN Chini, DJ Baker, JM van Deurse, NK LeBrasseur
    Molecular Metabolism, 2022-12-09;67(0):101652.
    Species: Mouse
    Sample Types: Plasma
  42. Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia
    Authors: X Ji, L Han, W Zhang, L Sun, S Xu, X Qiu, S Fan, Z Li
    Bmc Biology, 2022-11-09;20(1):251.
    Species: Mouse
    Sample Types: Tissue Homogenates
  43. Molecular and Cellular Markers in Chlorhexidine-Induced Peritoneal Fibrosis in Mice
    Authors: N Brezovec, N Kojc, A Erman, M Hladnik, J Stergar, M Milani?, M Tomši?, S ?u?nik, S Sodin-Šemr, M Perše, K Lakota
    Biomedicines, 2022-10-27;10(11):.
    Species: Mouse
    Sample Types: Serum
  44. Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model
    Authors: FA Schwartz, L Christophe, K Thomsen, S Baekdal, M Pals Bendi, M Jørgensen, IK Bull Rasmu, AS Laulund, N Høiby, C Moser
    Frontiers in Microbiology, 2022-09-09;13(0):988386.
    Species: Mouse
    Sample Types: Tissue Homogenates
  45. Potential Health-Promoting Effects of Two Candidate Probiotics Isolated from Infant Feces Using an Immune-Based Screening Strategy
    Authors: H Liang, X Ze, S Wang, Y Wang, C Peng, R Cheng, F Jiang, S Wu, R He, F He, X Zhang, X Shen
    Nutrients, 2022-09-03;14(17):.
    Species: Mouse
    Sample Types: Serum
  46. Dersimelagon, a novel oral melanocortin 1 receptor agonist, demonstrates disease-modifying effects in preclinical models of systemic sclerosis
    Authors: M Kondo, T Suzuki, Y Kawano, S Kojima, M Miyashiro, A Matsumoto, G Kania, P B?yszczuk, RL Ross, P Mulipa, F Del Galdo, Y Zhang, JHW Distler
    Arthritis Research & Therapy, 2022-09-01;24(1):210.
    Species: Mouse
    Sample Types: Serum
  47. Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation
    Authors: DC Humphries, R Mills, C Boz, BJ McHugh, N Hirani, AG Rossi, A Pedersen, HT Schambye, RJ Slack, H Leffler, UJ Nilsson, W Wang, T Sethi, AC Mackinnon
    Frontiers in Pharmacology, 2022-08-08;13(0):949264.
    Species: Mouse
    Sample Types: BALF
  48. Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis
    Authors: L Li, J Freitag, C Asbrand, B Munteanu, BT Wang, E Zezina, M Didier, G Thill, C Rocher, M Herrmann, N Biesemann
    Scientific Reports, 2022-07-12;12(1):11830.
    Species: Mouse
    Sample Types: Plasma
  49. Targeting IL-1beta as an immune preventive and therapeutic modality for K-ras mutant lung cancer
    Authors: B Yuan, MJ Clowers, WV Velasco, S Peng, Q Peng, Y Shi, M Ramos-Cast, M Zarghooni, S Yang, RL Babcock, SH Chang, JV Heymach, J Zhang, EJ Ostrin, SS Watowich, H Kadara, SJ Moghaddam
    JCI Insight, 2022-06-08;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  50. Re-programming mouse liver-resident invariant natural killer T cells for suppressing hepatic and diabetogenic autoimmunity
    Authors: CS Umeshappa, P Solé, J Yamanouchi, S Mohapatra, BGJ Surewaard, J Garnica, S Singha, D Mondal, E Cortés-Vic, C D'Mello, A Mason, P Kubes, P Serra, Y Yang, P Santamaria
    Nature Communications, 2022-06-07;13(1):3279.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Integrative analysis of network pharmacology and proteomics to identify key targets of Tuomin-Zhiti-Decoction for allergic rhinitis
    Authors: J Cheng, M Zhang, Y Zheng, J Wang, Q Wang
    Oncogene, 2022-06-06;0(0):115448.
    Species: Mouse
    Sample Types: Serum
  52. DNA damage to beta cells in culture recapitulates features of senescent beta cells that accumulate in type 1 diabetes
    Authors: G Brawerman, J Pipella, PJ Thompson
    Molecular Metabolism, 2022-06-02;0(0):101524.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  53. Human Mesenchymal Stromal Cells Resolve Lipid Load in High Fat Diet-Induced Non-Alcoholic Steatohepatitis in Mice by Mitochondria Donation
    Authors: S Nickel, M Christ, S Schmidt, J Kosacka, H Kühne, M Roderfeld, T Longerich, L Tietze, I Bosse, MJ Hsu, P Stock, E Roeb, B Christ
    Cells, 2022-06-02;11(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  54. Pharmacokinetic/Pharmacodynamic Evaluation of a New Purine-2,6-Dione Derivative in Rodents with Experimental Autoimmune Diseases
    Authors: A ?wierczek, K Pociecha, H Plutecka, M ?lusarczyk, G Ch?o?-Rzep, E Wyska
    Pharmaceutics, 2022-05-19;14(5):.
    Species: Mouse
    Sample Types: Serum
  55. Metagenomic Analysis Reveals a Mitigating Role for Lactobacillus paracasei and Bifidobacterium animalis in Experimental Periodontitis
    Authors: F Wu, B Fang, G Wuri, L Zhao, F Liu, M Zhang
    Nutrients, 2022-05-19;14(10):.
    Species: Mouse
    Sample Types: Serum
  56. Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response
    Authors: EV Shmeleva, M Gomez de A, J Wagner, AJ Enright, AJ Macpherson, BJ Ferguson, GL Smith
    PloS Pathogens, 2022-04-21;18(4):e1009854.
    Species: Mouse
    Sample Types: Tissue Homogenates
  57. Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis
    Authors: C Yi, J Liu, W Deng, C Luo, J Qi, M Chen, H Xu
    Journal of Neuroinflammation, 2022-04-05;19(1):78.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  58. Identification of gingerenone A as a novel senolytic compound
    Authors: R Moaddel, M Rossi, S Rodriguez, R Munk, M Khadeer, K Abdelmohse, M Gorospe, L Ferrucci
    PLoS ONE, 2022-03-29;17(3):e0266135.
    Species: Mouse
    Sample Types: Cell Lysates
  59. Systemic and single cell level responses to 1�nm size biomaterials demonstrate distinct biological effects revealed by multi-omics atlas
    Authors: T Zhang, T Lei, R Yan, B Zhou, C Fan, Y Zhao, S Yao, H Pan, Y Chen, B Wu, Y Yang, L Hu, S Gu, X Chen, F Bao, Y Li, H Xie, R Tang, X Chen, Z Yin
    Bioactive materials, 2022-03-26;18(0):199-212.
    Species: Mouse
    Sample Types: Serum
  60. Obesity phenotype induced by high-fat diet leads to maternal-fetal constraint, placental inefficiency, and fetal growth restriction in mice
    Authors: APV Sanches, JL de Oliveir, MS Ferreira, BS Lima, JÉ Miyamoto, LAP Simino, MA Torsoni, AS Torsoni, M Milanski, LM Ignácio-So
    The Journal of nutritional biochemistry, 2022-03-03;0(0):108977.
    Species: Mouse
    Sample Types: Amniotic Fluid
  61. Immune dysfunction induced by 2,6-dichloro-1,4-benzoquinone, an emerging water disinfection byproduct, due to the defects of host-microbiome interactions
    Authors: J Wang, T Liu, L Liu, X Chen, X Zhang, H Du, C Wang, J Li, J Li
    Chemosphere, 2022-01-28;294(0):133777.
    Species: Mouse
    Sample Types: Serum
  62. Gammaherpesvirus Alters Alveolar Macrophages According to the Host Genetic Background and Promotes Beneficial Inflammatory Control over Pneumovirus Infection
    Authors: G Gilliaux, D Desmecht
    Viruses, 2022-01-06;14(1):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  63. Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice
    Authors: Y Wu, E Li, M Knight, G Adeniyi-Ip, LZ Song, AR Burns, AC Gazzinelli, R Fujiwara, ME Bottazzi, JE Weatherhea
    PloS Neglected Tropical Diseases, 2021-12-16;15(12):e0010050.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  64. Study on the Molecular Basis of Huanglian Jiedu Decoction Against Atopic Dermatitis Integrating Chemistry, Biochemistry, and Metabolomics Strategies
    Authors: J Chen, S Chen, J Chen, B Shen, Z Jiang, Y Xu
    Frontiers in Pharmacology, 2021-12-14;12(0):770524.
    Species: Mouse
    Sample Types: Serum
  65. Pharmacokinetics and Pharmacodynamics of T-Cell Bispecifics in the Tumour Interstitial Fluid
    Authors: MJ Eigenmann, TV Karlsen, M Wagner, O Tenstad, T Weinzierl, T Fauti, HP Grimm, T Skogstrand, C Klein, J Sam, P Umana, M Bacac, H Wiig, AC Walz
    Pharmaceutics, 2021-12-07;13(12):.
    Species: Mouse
    Sample Types: Plasma
  66. Effects of Importin alpha1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice
    Authors: K Sakurai, T Itou, M Morita, E Kasahara, T Moriyama, T Macpherson, T Ozawa, Y Miyamoto, Y Yoneda, A Sekiyama, M Oka, T Hikida
    PLoS ONE, 2021-11-12;16(11):e0258364.
    Species: Mouse
    Sample Types: Plasma
  67. Effect of a Fiber D-Limonene-Enriched Food Supplement on Intestinal Microbiota and Metabolic Parameters of Mice on a High-Fat Diet
    Authors: MC Valerii, S Turroni, C Ferreri, M Zaro, A Sansone, A Dalpiaz, G Botti, L Ferraro, R Spigarelli, I Bellocchio, F D'Amico, E Spisni
    Pharmaceutics, 2021-10-21;13(11):.
    Species: Mouse
    Sample Types: Serum
  68. Evaluation of a Murine Model for Testing Antimicrobial Implant Materials in the Blood Circulation System
    Authors: C Moerke, M Kloss, K Wulf, S Illner, S Kischkel, M Sombetzki, N Grabow, E Reisinger, A Öner, H Ince
    Biomedicines, 2021-10-13;9(10):.
    Species: Mouse
    Sample Types: Plasma
  69. Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model
    Authors: M Hafner, S Paukner, WW Wicha, B Hrva?i?, M Cedilak, I Faraho, SP Gelone
    PLoS ONE, 2021-09-29;16(9):e0237659.
    Species: Mouse
    Sample Types: Tissue Homogenates
  70. Adipose expression of CREB3L3 modulates body weight during obesity
    Authors: MA McCann, Y Li, M Muñoz, V Gil, G Qiang, J Cordoba-Ch, M Blüher, S Duncan, CW Liew
    Scientific Reports, 2021-09-29;11(1):19400.
    Species: Mouse
    Sample Types: Plasma
  71. The Anti-Atherosclerotic Action of FFAR4 Agonist TUG-891 in ApoE-Knockout Mice Is Associated with Increased Macrophage Polarization towards M2 Phenotype
    Authors: A Kiepura, K Stachyra, A Wi?niewska, K Ku?, K Czepiel, M Suski, M Ulatowska-, M Surmiak, R Olszanecki
    International Journal of Molecular Sciences, 2021-09-09;22(18):.
    Species: Mouse
    Sample Types: Plasma
  72. Doxorubicin Paradoxically Ameliorates Tumor-Induced Inflammation in Young Mice
    Authors: IY Abdelgawad, MKO Grant, FE Popescu, DA Largaespad, BN Zordoky
    International Journal of Molecular Sciences, 2021-08-21;22(16):.
    Species: Mouse
    Sample Types: Serum
  73. Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis
    Authors: R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, D Cesana, P Gallina, M Norelli, L Basso-Ricc, A Bondanza, G Cavalli, M Ponzoni, L Dagna, C Doglioni, A Aiuti, I Merelli, R Di Micco, E Montini
    Nature Communications, 2021-07-27;12(1):4559.
    Species: Mouse
    Sample Types: Serum
  74. Increased Endocytosis of Cadmium-Metallothionein through the 24p3 Receptor in an In Vivo Model with Reduced Proximal Tubular Activity
    Authors: IP Zavala-Gue, MS Ortega-Rom, J Narváez-Mo, TL Jacobo-Est, WK Lee, L Arreola-Me, F Thévenod, OC Barbier
    International Journal of Molecular Sciences, 2021-07-06;22(14):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  75. Serum amyloid A promotes inflammation-associated damage and tumourigenesis in a mouse model of colitis-associated cancer
    Authors: TA Davis, D Conradie, P Shridas, FC de Beer, AM Engelbrech, WJS de Villier
    Cellular and Molecular Gastroenterology and Hepatology, 2021-07-02;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  76. Intralesional injection of rose bengal augments the efficacy of gemcitabine chemotherapy against pancreatic tumors
    Authors: P Innamarato, J Morse, A Mackay, S Asby, M Beatty, J Blauvelt, S Kidd, JE Mullinax, AA Sarnaik, S Pilon-Thom
    BMC Cancer, 2021-06-30;21(1):756.
    Species: Mouse
    Sample Types: Serum
  77. The PI3K&delta inhibitor parsaclisib ameliorates pathology and reduces autoantibody formation in preclinical models of systemic lupus erythematosus and Sj?gren's syndrome
    Authors: MD Scuron, BL Fay, AJ Connell, J Oliver, PA Smith
    International immunopharmacology, 2021-06-29;98(0):107904.
    Species: Mouse
    Sample Types: Saliva
  78. Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses
    Authors: B Uyanik, AR Goloudina, A Akbarali, BB Grigorash, AV Petukhov, S Singhal, E Eruslanov, J Chaloyard, L Lagorgette, T Hadi, EV Baidyuk, H Sakai, L Tessarollo, B Ryffel, SJ Mazur, F Lirussi, C Garrido, E Appella, ON Demidov
    Nature Communications, 2021-06-15;12(1):3622.
    Species: Mouse
    Sample Types: Tissue Homogenates
  79. Wnt-Signaling Inhibitor Wnt-C59 Suppresses the Cytokine Upregulation in Multiple Organs of Lipopolysaccharide-Induced Endotoxemic Mice via Reducing the Interaction between beta-Catenin and NF-kappaB
    Authors: J Jang, J Song, I Sim, YV Kwon, Y Yoon
    International Journal of Molecular Sciences, 2021-06-10;22(12):.
    Species: Mouse
    Sample Types: Plasma
  80. Effective inactivated influenza vaccine for the elderly using a single-stranded RNA-based adjuvant
    Authors: YJ Bang, SH Hong, HJ Park, HW Kwak, YS Lee, JY Kim, HJ Park, SH Bae, HJ Kim, YH Kim, HL Ko, SI Park, H Kim, G Park, MS Park, J Chang, JH Nam
    Scientific Reports, 2021-06-07;11(1):11981.
    Species: Mouse
    Sample Types: BALF
  81. Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
    Authors: LK Donovan, A Delaidelli, SK Joseph, K Bielamowic, K Fousek, BL Holgado, A Manno, D Srikanthan, AZ Gad, R Van Ommere, D Przelicki, C Richman, V Ramaswamy, C Daniels, JG Pallota, T Douglas, ACM Joynt, J Haapasalo, C Nor, MC Vladoiu, CM Kuzan-Fisc, L Garzia, SC Mack, S Varadharaj, ML Baker, L Hendrikse, M Ly, K Kharas, P Balin, X Wu, L Qin, N Huang, AG Stucklin, AS Morrissy, FMG Cavalli, B Luu, R Suarez, P De Antonel, A Michealraj, A Rastan, M Hegde, M Komosa, O Sirbu, SA Kumar, Z Abdullaev, CC Faria, S Yip, J Hukin, U Tabori, C Hawkins, K Aldape, M Daugaard, JM Maris, PH Sorensen, N Ahmed, MD Taylor
    Nature Medicine, 2021-06-01;0(0):.
    Species: Mouse
    Sample Types: CSF
  82. Mouse primary microglia respond differently to LPS and poly(I:C) in vitro
    Authors: Y He, N Taylor, X Yao, A Bhattachar
    Scientific Reports, 2021-05-17;11(1):10447.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  83. Enhancing Cystic Fibrosis Immune Regulation
    Authors: AM van Heecke, MT Sutton, DR Fletcher, CA Hodges, AI Caplan, TL Bonfield
    Frontiers in Pharmacology, 2021-05-13;12(0):573065.
    Species: Mouse
    Sample Types: BALF
  84. Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model
    Authors: SS Qin, BJ Han, A Williams, KM Jackson, R Jewell, AC Chacon, EM Lord, DC Linehan, M Kim, A Reuben, SA Gerber, PA Prieto
    Cancers, 2021-05-11;13(10):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  85. Vaccination by Two DerG LEAPS Conjugates Incorporating Distinct Proteoglycan (PG, Aggrecan) Epitopes Provides Therapy by Different Immune Mechanisms in a Mouse Model of Rheumatoid Arthritis
    Authors: DH Zimmerman, K Mikecz, A Markovics, RE Carambula, JC Ciemielews, DM Toth, TT Glant, KS Rosenthal
    Vaccines, 2021-05-02;9(5):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Regulation of Helicobacter-induced gastritis by programmed death ligand 1-expressing classical dendritic cells
    Authors: DM Go, SH Lee, SH Lee, SH Woo, K Kim, K Kim, KS Park, JH Park, SJ Ha, WH Kim, JH Choi, DY Kim
    Cellular and Molecular Gastroenterology and Hepatology, 2021-04-21;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  87. Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses
    Authors: JM Powers, NN Haese, M Denton, T Ando, C Kreklywich, K Bonin, CE Streblow, N Kreklywich, P Smith, R Broeckel, V DeFilippis, TE Morrison, MT Heise, DN Streblow
    PloS Neglected Tropical Diseases, 2021-04-01;15(4):e0009308.
    Species: Mouse
    Sample Types: Tissue Homogenates
  88. Neuromedin U Suppresses Collagen-Induced Arthritis through ILC2-Th2 Activation
    Authors: Y Zhang, Y Qin, Z Chen
    Journal of Immunology Research, 2021-03-08;2021(0):5599439.
    Species: Mouse
    Sample Types: Plasma
  89. Loss of cIAP1 in Endothelial Cells Limits Metastatic Extravasation through Tumor-Derived Lymphotoxin Alpha
    Authors: L Vasilikos, K Hänggi, LM Spilgies, S Kisele, S Rufli, WW Wong
    Cancers, 2021-02-03;13(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  90. Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response
    Authors: SP Korpela, TK Hinz, A Oweida, J Kim, J Calhoun, R Ferris, RA Nemenoff, SD Karam, ET Clambey, LE Heasley
    Journal of Translational Medicine, 2021-01-23;19(1):43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  91. The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson's disease
    Authors: Z Dwyer, M Chaiquin, J Landrigan, K Ayoub, P Shail, J Rocha, CL Childers, KB Storey, DJ Philpott, H Sun, S Hayley
    Journal of Neuroinflammation, 2021-01-09;18(1):20.
    Species: Mouse
    Sample Types: Plasma
  92. Probiotic Lactobacillus fermentum strain JDFM216 improves cognitive behavior and modulates immune response with gut microbiota
    Authors: MR Park, M Shin, D Mun, SY Jeong, DY Jeong, M Song, G Ko, T Unno, Y Kim, S Oh
    Scientific Reports, 2020-12-10;10(1):21701.
    Species: Mouse
    Sample Types: Serum
  93. Complement C5 activation promotes type 2 diabetic kidney disease via activating STAT3 pathway and disrupting the gut-kidney axis
    Authors: L Li, T Wei, S Liu, C Wang, M Zhao, Y Feng, L Ma, Y Lu, P Fu, J Liu
    Journal of Cellular and Molecular Medicine, 2020-12-06;0(0):.
    Species: Mouse
    Sample Types: Serum
  94. Shift work influences the outcomes of Chlamydia infection and pathogenesis
    Authors: SR Lundy, S Richardson, A Ramsey, D Ellerson, Y Fengxia, S Onyeabor, W Kirlin, W Thompson, CM Black, JP DeBruyne, AJ Davidson, LC Immergluck, U Blas-Macha, FO Eko, JU Igietseme, Q He, YO Omosun
    Scientific Reports, 2020-09-21;10(1):15389.
    Species: Mouse
    Sample Types: Vaginal Lavage
  95. Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn's disease
    Authors: L Allais, S Verschuere, T Maes, R De Smet, S Devriese, GB Gonzales, H Peeters, K Van Crombr, C Bachert, M De Vos, GG Brusselle, KR Bracke, CA Cuvelier, D Laukens
    PLoS ONE, 2020-08-06;15(8):e0236657.
    Species: Mouse
    Sample Types: Tissue Homogenates
  96. Marginal Zone Formation Requires ACKR3 Expression on B Cells
    Authors: E Radice, R Ameti, S Melgrati, M Foglierini, P Antonello, RAK Stahl, S Thelen, D Jarrossay, M Thelen
    Cell Rep, 2020-08-04;32(5):107951.
    Species: Mouse
    Sample Types: Cell Culture Supernates, Whole Cells
  97. Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity
    Authors: A Filiberti, GB Gmyrek, ML Montgomery, R Sallack, DJJ Carr
    Invest. Ophthalmol. Vis. Sci., 2020-08-03;61(10):24.
    Species: Mouse
    Sample Types: Tissue Homogenates
  98. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages
    Authors: NA Pease, MS Shephard, M Sertorio, SE Waltz, LMP Vinnedge
    Cancers (Basel), 2020-07-17;12(7):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  99. Epitope Shaving Promotes Fungal Immune Evasion
    Authors: DS Childers, GM Avelar, JM Bain, A Pradhan, DE Larcombe, MG Netea, LP Erwig, NAR Gow, AJP Brown
    MBio, 2020-07-07;11(4):.
    Species: Mouse
    Sample Types: Whole Blood
  100. Etoposide-mediated interleukin-8 secretion from bone marrow stromal cells induces hematopoietic stem cell mobilization
    Authors: KW Kang, SJ Lee, JH Kim, BH Lee, SJ Kim, Y Park, BS Kim
    BMC Cancer, 2020-07-02;20(1):619.
    Species: Mouse
    Sample Types: Plasma
  101. Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice
    Authors: E Hadadi, W Taylor, XM Li, Y Aslan, M Villote, J Rivière, G Duvallet, C Auriau, S Dulong, I Raymond-Le, S Provot, A Bennaceur-, H Acloque
    Nat Commun, 2020-06-24;11(1):3193.
    Species: Mouse
    Sample Types: Plasma
  102. Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions
    Authors: X Han, Y Lu, J Xie, E Zhang, H Zhu, H Du, K Wang, B Song, C Yang, Y Shi, Z Cao
    Nat Nanotechnol, 2020-06-01;0(0):.
    Species: Mouse
    Sample Types: Serum
  103. TGF-beta1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In�Vivo
    Authors: K Lynch, O Treacy, X Chen, N Murphy, P Lohan, MN Islam, E Donohoe, MD Griffin, L Watson, S McLoughlin, G O'Malley, AE Ryan, T Ritter
    Mol. Ther., 2020-05-30;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  104. Commiphora Extract Mixture Ameliorates Monosodium Iodoacetate-Induced Osteoarthritis
    Authors: D Lee, MK Ju, H Kim
    Nutrients, 2020-05-19;12(5):.
    Species: Mouse
    Sample Types: Serum
  105. Maintaining immunogenicity of blood stage and sexual stage subunit malaria vaccines when formulated in combination
    Authors: EM Parzych, K Miura, CA Long, JM Burns
    PLoS ONE, 2020-04-29;15(4):e0232355.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  106. Anti-HER2 induced myeloid cell alterations correspond with increasing vascular maturation in a murine model of HER2+ breast cancer
    Authors: MJ Bloom, AM Jarrett, TA Triplett, AK Syed, T Davis, TE Yankeelov, AG Sorace
    BMC Cancer, 2020-04-28;20(1):359.
    Species: Mouse
    Sample Types: Cell Lysates
  107. Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection
    Authors: Q Zhang, J Hu, JW Feng, XT Hu, T Wang, WX Gong, K Huang, YX Guo, Z Zou, X Lin, R Zhou, YQ Yuan, AD Zhang, H Wei, G Cao, C Liu, LL Chen, ML Jin
    Genome Biol., 2020-04-28;21(1):99.
    Species: Mouse
    Sample Types: Tissue Homogenates
  108. Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation
    Authors: T Koopmans, L Hesse, MC Nawijn, K Kumawat, MH Menzen, I Sophie T B, R Smits, ERM Bakker, M van den Be, GH Koppelman, V Guryev, R Gosens
    Sci Rep, 2020-04-21;10(1):6754.
    Species: Mouse
    Sample Types: Tissue Homogenates
  109. Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability
    Authors: S Ruiz, F Vardon-Bou, M Buléon, C Guilbeau-F, MH Séguelas, JM Conil, JP Girolami, I Tack, V Minville
    J Transl Med, 2020-04-19;18(1):174.
    Species: Mouse
    Sample Types: Serum
  110. A combination of genetics and microbiota influences the severity of the obesity phenotype in diet-induced obesity
    Authors: M Smoczek, M Vital, D Wedekind, M Basic, NH Zschemisch, DH Pieper, A Siebert, A Bleich, M Buettner
    Sci Rep, 2020-04-09;10(1):6118.
    Species: Mouse
    Sample Types: Serum
  111. Exosome-based delivery of super-repressor I&kappaB&alpha relieves sepsis-associated organ damage and mortality
    Authors: H Choi, Y Kim, A Mirzaaghas, J Heo, YN Kim, JH Shin, S Kim, NH Kim, ES Cho, J In Yook, TH Yoo, E Song, P Kim, EC Shin, K Chung, K Choi, C Choi
    Sci Adv, 2020-04-08;6(15):eaaz6980.
    Species: Mouse
    Sample Types: Plasma
  112. Genetic Deficiency of the Histamine H4-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice
    Authors: B Schirmer, T Rother, I Bruesch, A Bleich, C Werlein, D Jonigk, R Seifert, D Neumann
    Cancers (Basel), 2020-04-08;12(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  113. ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis
    Authors: Z Shangxun, L Junjie, Z Wei, W Yutong, J Wenyuan, L Shanshou, W Yanjun, W Qianmei, F Zhusheng, Y Chaoping, Z Ran, Y Wen, H Yang
    Mediators Inflamm., 2020-03-24;2020(0):9607535.
    Species: Mouse
    Sample Types: Serum
  114. Inhibition of bone morphogenetic protein 6 receptors ameliorates Sj�gren's syndrome in mice
    Authors: H Yin, L Kalra, Z Lai, MC Guimaro, L Aber, BM Warner, D Michael, N Zhang, J Cabrera-Pe, A Karim, WD Swaim, S Afione, A Voigt, CQ Nguyen, PB Yu, DB Bloch, JA Chiorini
    Sci Rep, 2020-02-19;10(1):2967.
    Species: Mouse
    Sample Types: Serum
  115. Muscle Injury Induces Postoperative Cognitive Dysfunction
    Authors: L Guéniot, V Lepere, GF De Medeiro, A Danckaert, P Flamant, M Le Dudal, O Langeron, PL Goossens, F Chrétien, G Jouvion
    Sci Rep, 2020-02-17;10(1):2768.
    Species: Mouse
    Sample Types: Tissue Homogenates
  116. Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation
    Authors: MKO Grant, IY Abdelgawad, CA Lewis, BN Zordoky
    Int J Mol Sci, 2020-02-14;21(4):.
    Species: Mouse
    Sample Types: Serum
  117. HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia
    Authors: JR Huot, LJ Novinger, F Pin, A Bonetto
    Dis Model Mech, 2020-01-24;0(0):.
    Species: Mouse
    Sample Types: Plasma
  118. Allergic inflammation alters the lung microbiome and hinders synergistic co-infection with H1N1 influenza virus and Streptococcus pneumoniae in C57BL/6 mice
    Authors: KS LeMessurie, AR Iverson, TC Chang, M Palipane, P Vogel, JW Rosch, AE Samarasing
    Sci Rep, 2019-12-18;9(1):19360.
    Species: Mouse
    Sample Types: BALF
  119. Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in non-obese diabetic mice
    Authors: MC Simon, AL Reinbeck, C Wessel, J Heindirk, T Jelenik, K Kaul, J Arreguin-C, A Strom, M Blaut, F Bäckhed, V Burkart, M Roden
    J. Biol. Chem., 2019-12-10;0(0):.
    Species: Mouse
    Sample Types: Serum
  120. FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells
    Authors: J Gimenes-Ju, N Owuar, HR Vari, W Li, N Xander, S Kotnala, US Sajjan
    Sci Rep, 2019-12-03;9(1):18180.
    Species: Mouse
    Sample Types: BALF
  121. Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock
    Authors: T Delvaeye, MAJ De Smet, S Verwaerde, E Decrock, A Czekaj, RE Vandenbrou, K Lemeire, A Gonçalves, W Declercq, P Vandenabee, DV Krysko, L Leybaert
    Sci Rep, 2019-11-12;9(1):16623.
    Species: Mouse
    Sample Types: Plasma
  122. Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization
    Authors: A Schulz, L Jiang, L de Vor, M Ehrström, F Wermeling, L Eidsmo, K Melican
    Cell Rep, 2019-10-29;29(5):1074-1081.e5.
    Species: Mouse
    Sample Types: Tissue Homogenates
  123. Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment
    Authors: BN Mills, KA Connolly, J Ye, JD Murphy, TP Uccello, BJ Han, T Zhao, MG Drage, A Murthy, H Qiu, A Patel, NM Figueroa, CJ Johnston, PA Prieto, NK Egilmez, BA Belt, EM Lord, DC Linehan, SA Gerber
    Cell Rep, 2019-10-08;29(2):406-421.e5.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice
    Authors: F Hempel, M Roderfeld, R Savai, A Sydykov, K Irungbam, R Schermuly, R Voswinckel, K Köhler, Y Churin, L Kiss, J Bier, J Pons-Kühne, E Roeb
    Cells, 2019-10-07;8(10):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  125. Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
    Authors: S Gooding, SWZ Olechnowic, EV Morris, AE Armitage, J Arezes, J Frost, E Repapi, JR Edwards, N Ashley, C Waugh, N Gray, E Martinez-H, PJ Lim, SR Pasricha, H Knowles, AJ Mead, K Ramasamy, H Drakesmith, CM Edwards
    Nat Commun, 2019-10-04;10(1):4533.
    Species: Mouse
    Sample Types: Bone Marrow Plasma
  126. BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes
    Authors: PJ Thompson, A Shah, H Apostolopo, A Bhushan
    Int J Mol Sci, 2019-09-26;20(19):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  127. Th1-biased immunoadjuvant effect of the recombinant B subunit of an Escherichia coli heat-labile enterotoxin on an inactivated PRRSV antigen via intranasal immunization in mice
    Authors: F Su, L Xu, Y Xue, J Li, Y Fu, B Yu, S Wang, X Yuan
    J. Vet. Med. Sci., 2019-09-16;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  128. Comprehensive Analysis of the Safety Profile of a Single-Stranded RNA Nano-Structure Adjuvant
    Authors: HJ Park, HL Ko, DH Won, DB Hwang, YS Shin, HW Kwak, HJ Kim, JW Yun, JH Nam
    Pharmaceutics, 2019-09-07;11(9):.
    Species: Mouse
    Sample Types: Serum
  129. Performance of a glucose-reactive enzyme-based biofuel cell system for biomedical applications
    Authors: WY Jeon, JH Lee, K Dashnyam, YB Choi, TH Kim, HH Lee, HW Kim, HH Kim
    Sci Rep, 2019-07-26;9(1):10872.
    Species: Mouse
    Sample Types: Whole Cells
  130. AMPK as a potential pharmacological target for alleviating LPS-induced acute lung injury partly via NLRC4 inflammasome pathway inhibition
    Authors: Y He, K Xu, Y Wang, X Chao, B Xu, J Wu, J Shen, W Ren, Y Hu
    Exp. Gerontol., 2019-07-15;125(0):110661.
    Species: Mouse
    Sample Types: BALF
  131. EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection
    Authors: M Swidergall, NV Solis, Z Wang, QT Phan, ME Marshall, MS Lionakis, E Pearlman, SG Filler
    Cell Rep, 2019-07-09;28(2):423-433.e5.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades
    Authors: X Lu, Y Zhu, R Bai, Z Wu, W Qian, L Yang, R Cai, H Yan, T Li, V Pandey, Y Liu, PE Lobie, C Chen, T Zhu
    Nat Nanotechnol, 2019-06-24;14(7):719-727.
    Species: Mouse
    Sample Types: BALF
  133. Depletion of Intestinal Microbiome Partially Rescues Bone Loss in Sickle Cell Disease Male Mice
    Authors: S Tavakoli, L Xiao
    Sci Rep, 2019-06-17;9(1):8659.
    Species: Mouse
    Sample Types: Serum
  134. Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype
    Authors: C Rudyk, Z Dwyer, S Hayley
    J Neuroinflammation, 2019-06-07;16(1):120.
    Species: Mouse, Transgenic Mouse
    Sample Types: Plasma
  135. The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer
    Authors: E Pastille, MH Wasmer, A Adamczyk, VP Vu, LF Mager, NNT Phuong, V Palmieri, C Simillion, W Hansen, S Kasper, M Schuler, B Muggli, KD McCoy, J Buer, I Zlobec, AM Westendorf, P Krebs
    Mucosal Immunol, 2019-06-05;0(0):.
    Species: Mouse, Transgenic Mouse
    Sample Types: Tissue Culture Supernates
  136. Correlation network analysis shows divergent effects of a long-term, high-fat diet and exercise on early stage osteoarthritis phenotypes in mice
    Authors: TM Griffin, A Batushansk, J Hudson, EBP Lopes
    J Sport Health Sci, 2019-05-24;9(2):119-131.
    Species: Mouse
    Sample Types: Serum
  137. Papaver nudicaule (Iceland poppy) alleviates lipopolysaccharide-induced inflammation through inactivating NF-?B and STAT3
    Authors: JH Oh, M Yun, D Park, IJ Ha, CK Kim, DW Kim, EO Kim, SG Lee
    BMC Complement Altern Med, 2019-04-29;19(1):90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. Adipose Tissue Regulates Pulmonary Pathology during TB Infection
    Authors: JP Ayyappan, U Ganapathi, K Lizardo, C Vinnard, S Subbian, D Perlin, JF Nagajyothi
    MBio, 2019-04-16;10(2):.
    Species: Mouse
    Sample Types: Serum
  139. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense
    Authors: CP Parlet, JS Kavanaugh, HA Crosby, HA Raja, T El-Elimat, DA Todd, CJ Pearce, NB Cech, NH Oberlies, AR Horswill
    Cell Rep, 2019-04-02;27(1):187-198.e6.
    Species: Mouse
    Sample Types: Tissue Homogenates
  140. Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
    Authors: KJ Warren, JD Dickinson, AJ Nelson, TA Wyatt, DJ Romberger, JA Poole
    Respir. Res., 2019-03-07;20(1):51.
    Species: Mouse
    Sample Types: BALF
  141. Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice
    Authors: SD Hwang, JH Song, Y Kim, JH Lim, MY Kim, EN Kim, YA Hong, S Chung, BS Choi, YS Kim, CW Park
    Cell Death Dis, 2019-03-04;10(3):219.
    Species: Mouse
    Sample Types: Serum
  142. Loading ceftriaxone, vancomycin, and Bifidobacteria bifidum TMC3115 to neonatal mice could differently and consequently affect intestinal microbiota and immunity in adulthood
    Authors: R Cheng, J Guo, F Pu, C Wan, L Shi, H Li, Y Yang, C Huang, M Li, F He
    Sci Rep, 2019-03-01;9(1):3254.
    Species: Mouse
    Sample Types: Serum
  143. Physiology and effects of nucleosides in mice lacking all four adenosine receptors
    Authors: C Xiao, N Liu, KA Jacobson, O Gavrilova, ML Reitman
    PLoS Biol., 2019-03-01;17(3):e3000161.
    Species: Mouse
    Sample Types: Plasma
  144. A novel, multiple-antigen pneumococcal vaccine protects against lethal Streptococcus pneumoniae challenge
    Authors: WY Chan, C Entwisle, G Ercoli, E Ramos-Sevi, A McIlgorm, P Cecchini, C Bailey, O Lam, G Whiting, N Green, D Goldblatt, JX Wheeler, JS Brown
    Infect. Immun., 2019-02-21;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  145. CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB
    Authors: YL Hsu, MC Yen, WA Chang, PH Tsai, YC Pan, SH Liao, PL Kuo
    Breast Cancer Res., 2019-02-12;21(1):23.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  146. Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model
    Authors: H Furuya, OTM Chan, I Pagano, C Zhu, N Kim, R Peres, K Hokutan, S Alter, P Rhode, CJ Rosser
    J Transl Med, 2019-01-17;17(1):29.
    Species: Mouse
    Sample Types: Urine
  147. The effect of the cholinergic anti-inflammatory pathway on collagen-induced arthritis involves the modulation of dendritic cell differentiation
    Authors: D Liu, T Li, H Luo, X Zuo, S Liu, S Wu
    Arthritis Res. Ther., 2018-11-28;20(1):263.
    Species: Mouse
    Sample Types:
  148. The Interaction of miR-378i-Skp2 Regulates Cell Senescence in Diabetic Nephropathy
    Authors: YC Tsai, PL Kuo, MC Kuo, WW Hung, LY Wu, WA Chang, PH Wu, SC Lee, HC Chen, YL Hsu
    J Clin Med, 2018-11-22;7(12):.
    Species: Mouse
    Sample Types: Urine
  149. Systemic vascular leakage induced in mice by Russell's viper venom from Pakistan
    Authors: A Rucavado, T Escalante, E Camacho, JM Gutiérrez, JW Fox
    Sci Rep, 2018-10-31;8(1):16088.
    Species: Mouse
    Sample Types: Plasma
  150. Lack of vitamin D signalling per se does not aggravate cardiac functional impairment induced by myocardial infarction in mice
    Authors: K Ford, N Latic, S Slavic, U Zeitz, M Dolezal, O Andrukhov, RG Erben, O Andrukhova
    PLoS ONE, 2018-10-01;13(10):e0204803.
    Species: Mouse
    Sample Types: Serum
  151. A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice
    Authors: AD Griffith, AK Zaidi, A Pietro, M Hadiono, JS Yang, R Davis, DL Popkin
    Sci Rep, 2018-09-27;8(1):14451.
    Species: Mouse
    Sample Types: Plasma
  152. 4-1BB enhancement of CAR T function requires NF-?B and TRAFs
    Authors: G Li, JC Boucher, H Kotani, K Park, Y Zhang, B Shrestha, X Wang, L Guan, N Beatty, D Abate-Daga, ML Davila
    JCI Insight, 2018-09-20;3(18):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  153. Prophylactic efficacy of orally administered Bacillus poly-?-glutamic acid, a non-LPS TLR4 ligand, against norovirus infection in mice
    Authors: W Lee, M Kim, SH Lee, HG Jung, JW Oh
    Sci Rep, 2018-06-06;8(1):8667.
    Species: Mouse
    Sample Types: Serum
  154. RNA sequencing analysis reveals quiescent microglia isolation methods from postnatal mouse brains and limitations of BV2 cells
    Authors: Y He, X Yao, N Taylor, Y Bai, T Lovenberg, A Bhattachar
    J Neuroinflammation, 2018-05-22;15(1):153.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  155. Chronic features of allergic asthma are enhanced in the absence of resistin-like molecule-beta
    Authors: KS LeMessurie, M Palipane, M Tiwary, B Gavin, AE Samarasing
    Sci Rep, 2018-05-04;8(1):7061.
    Species: Mouse
    Sample Types: Tissue Homogenates
  156. Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3
    Authors: TB Kang, JS Jeong, SH Yang, A Kovalenko, D Wallach
    Cell Death Differ., 2018-04-17;0(0):.
    Species: Mouse
    Sample Types: Plasma
  157. Synergistic actions of FGF2 and bone marrow transplantation mitigate radiation-induced intestinal injury
    Authors: BH Kim, HW Jung, SH Seo, H Shin, J Kwon, JM Suh
    Cell Death Dis, 2018-03-07;9(3):383.
    Species: Mouse
    Sample Types: Serum
  158. Leptin Signaling Mediates Obesity-associated CSC Enrichment and EMT in Preclinical TNBC Models
    Authors: LW Bowers, EL Rossi, SB McDonell, SS Doerstling, SA Khatib, CG Lineberger, JE Albright, X Tang, LA deGraffenr, SD Hursting
    Mol. Cancer Res., 2018-02-16;0(0):.
    Species: Mouse
    Sample Types: Serum
  159. Serum amyloid A3 is required for normal weight and immunometabolic function in mice
    Authors: JL Ather, ME Poynter
    PLoS ONE, 2018-02-01;13(2):e0192352.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  160. Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma
    Authors: JK Thompson, A Shukla, AL Leggett, PB Munson, JM Miller, MB MacPherson, SL Beuschel, HI Pass, A Shukla
    Oncotarget, 2017-12-06;9(1):293-305.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  161. CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation
    Authors: J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, W Huang, H Liu, AR Aref, E Ivanova, CP Paweletz, M Bowden, CW Zhou, GS Herter-Spr, JA Sorrentino, JE Bisi, PH Lizotte, AA Merlino, MM Quinn, LE Bufe, A Yang, Y Zhang, H Zhang, P Gao, T Chen, ME Cavanaugh, AJ Rode, E Haines, PJ Roberts, JC Strum, WG Richards, JH Lorch, S Parangi, V Gunda, GM Boland, R Bueno, S Palakurthi, GJ Freeman, J Ritz, WN Haining, NE Sharpless, H Arthanari, GI Shapiro, DA Barbie, NS Gray, KK Wong
    Cancer Discov, 2017-11-03;0(0):.
    Species: Transgenic Mouse
    Sample Types: BALF
  162. The yeast form of the fungus Candida albicans promotes persistence in the gut of gnotobiotic mice
    Authors: L Böhm, S Torsin, SH Tint, MT Eckstein, T Ludwig, JC Pérez
    PLoS Pathog., 2017-10-25;13(10):e1006699.
    Species: Mouse
    Sample Types: Tissue Homogenates
  163. Lactobacillus paracasei feeding improves immune control of influenza infection in mice
    Authors: N Belkacem, N Serafini, R Wheeler, M Derrien, L Boucinha, A Couesnon, N Cerf-Bensu, I Gomperts B, JP Di Santo, MK Taha, R Bourdet-Si
    PLoS ONE, 2017-09-20;12(9):e0184976.
    Species: Mouse
    Sample Types: Tissue Homogenates
  164. Lack of Histamine H4-Receptor Expression Aggravates TNBS-Induced Acute Colitis Symptoms in Mice
    Authors: EJ Wunschel, B Schirmer, R Seifert, D Neumann
    Front Pharmacol, 2017-09-13;8(0):642.
    Species: Mouse
    Sample Types: Tissue Homogenates
  165. Cannabinoid Receptor 2 Modulates Neutrophil Recruitment in a Murine Model of Endotoxemia
    Authors: TS Kapellos, C Recio, DR Greaves, AJ Iqbal
    Mediators Inflamm., 2017-08-09;2017(0):4315412.
    Species: Mouse
    Sample Types: Serum
  166. Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease
    Authors: SFH de Witte, AM Merino, M Franquesa, T Strini, JAA van Zoggel, SS Korevaar, F Luk, M Gargesha, L O'Flynn, D Roy, SJ Elliman, PN Newsome, CC Baan, MJ Hoogduijn
    Stem Cell Res Ther, 2017-06-08;8(1):140.
    Species: Mouse
    Sample Types: Serum
  167. Positive Prehabilitative Effect of Intense Treadmill Exercise for Ameliorating Cancer Cachexia Symptoms in a Mouse Model
    J Cancer, 2016-12-09;7(15):2378-2387.
    Species: Mouse
    Sample Types: Plasma
  168. Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII
    Authors: Ingrid Stroo
    Am. J. Physiol. Lung Cell Mol. Physiol, 2016-12-02;0(0):ajplung.00320.
    Species: Mouse
    Sample Types: Tissue Homogenates
  169. Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland
    Authors: Gerard J Graham
    Development, 2016-11-25;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  170. Complement Component 3 Regulates IFN-? Production by Plasmacytoid Dendritic Cells following TLR7 Activation by a Plant Virus-like Nanoparticle
    Authors: Alain Lamarre
    J. Immunol., 2016-11-18;0(0):.
    Species: Mouse
    Sample Types: Serum
  171. Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas
    Int J Cancer, 2016-08-29;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  172. Nrf2 Modulates Host Defense during Streptococcus pneumoniae Pneumonia in Mice
    Authors: JC Gomez, H Dang, JR Martin, CM Doerschuk
    J. Immunol, 2016-08-26;197(7):2864-79.
    Species: Mouse
    Sample Types: BALF
  173. CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
    Authors: Daniel Hsu
    Infect Immun, 2016-08-19;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  174. Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants
    Nat Commun, 2016-07-29;7(0):12304.
    Species: Mouse
    Sample Types: Serum

FAQs

  1. Are QC controls available for both the Luminex Discovery and High Performance Assays?

    • Controls are not offered for Luminex Discovery Assays, but may be formulated by the end user. A general guide may be available upon request. Controls are available for select Luminex High Performance Assays and can be found under the supplemental products tab on the product webpage. Some High Performance Luminex kits include controls and the controls will be listed in the materials provided section on the product datasheet. When included in the kit, controls are not sold separately.

  2. Can this assay be used for analysis of tissue homogenates?

    • This assay has been validated for use with tissue lysates, and a protocol is noted in the product insert for preparation of the tissue lysate.  The assay has not been validated for use with tissue homogenates.  In order to validate tissue homogenate for this assay, a good starting point would be homogenizing in a non-denaturing buffer with protease inhibitors. We recommend validating this sample type with Spike/Recovery and Linearity testing. Please contact Technical Support at techsupport@bio-techne.com with additional questions.

  3. What is the reason for the recommendation to use 35 µL sample volume, instead of the default 50 µL volume, for Luminex multiplex containing > 25 analytes, when assayed on Luminex MAGPIX® analyzer?

    • R&D Systems recommend 35 µL sample volume for > 25 analytes to control the number of beads in the sample load when using Luminex MAGPIX® analyzer. Luminex MAGPIX® analyzer is a non-flow-based reader which utilizes a magnet to hold the magnetic microparticles in a monolayer in a chamber where the beads are imaged and then processed by the software to generate data. Since MAGPIX® system pushes the entire Sample Load Volume into the chamber, multiplex assay containing > 25 analytes may overload the chamber capacity with 50 µL sample load default setting. The captured images can have too many beads in them to give accurate results, and some of the analytes/regions may present lower than desired bead counts. 

  4. Does the Luminex Mouse Magnetic Assay detect soluble form or membrane-bound analyte?

    • The sample types typically validated by R&D Systems for Luminex assays contain soluble form of proteins, and therefore it is expected that the soluble form of proteins are detected. It is possible there are assays that also detect the membrane form of respective target proteins, however, R&D Systems does not generally evaluate our assays against samples known to contain membrane-bound proteins.

  5. Why does the Luminex Assay Customization Tool provide the option to split based on dilution?

    • The feature to split based on dilution enables investigators to configure premix Luminex panels based on sample type (cell culture supernates, serum, and plasma). This keeps analytes requiring the same dilution factor within a single panel, while separating analytes requiring different dilutions. The recommended dilution factor for each analyte may be different for each sample type, and the suggested sample dilutions are built into the Luminex Customization Tool. Note that the suggested dilution factors are based on samples from healthy volunteers.

  6. Is the reconstituted standard a concentrate?

    • For Discovery Assays, each standard cocktail is a concentrate upon reconstitution with the volume specified on the Certificate of Analysis (CoA). After creating Standard 1 following the table in the product insert, the Standard 1 value is the concentration listed on the CoA.

  7. At what frequency should Calibration and Verification tests be performed?

    • It is recommended that a Calibration test be performed within one week prior to running an assay. A Verification test should be performed prior to data acquisition on the day of running an assay.

View all Luminex Assay FAQs
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Reviews for Mouse Luminex® Discovery Assay

Average Rating: 4.8 (Based on 33 Reviews)

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4 Star
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Mouse Luminex® Discovery Assay
By Anonymous on 09/22/2023
Sample Tested: Serum and Plasma

Mouse Luminex Discovery Assay
By Anonymous on 09/02/2021
Sample Tested: Serum-free Cell Culture Media

Mouse Luminex Discovery Assay
By Sergi Bayod on 07/28/2021
Sample Tested: EDTA Plasma

Mouse Magnetic Luminex Assay
By Zhenping Wang on 10/01/2020
Sample Tested: Tissue Homogenates

Mouse Magnetic Luminex Assay
By Anonymous on 06/02/2020
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Ashley Zuniga on 02/28/2020
Sample Tested: BMDCs media

Mouse Magnetic Luminex Assay
By Anonymous on 04/12/2018
Sample Tested: 4T1.2 mouse mammary carcinoma cells

Mouse Magnetic Luminex Assay
By Anonymous on 04/10/2018
Sample Tested: 7TD1 mouse hybridoma cell line

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 04/05/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Leslie Priddy on 04/01/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: A20 mouse B cell lymphoma cell line

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: 7TD1 mouse hybridoma cell line

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: Cell culture supernatant

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: Cell culture supernatant

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: BONE MARROW CELLS SUPERNATANT

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: Cell culture supernatant

Mouse Magnetic Luminex Assay
By Anonymous on 03/25/2018
Sample Tested: Cell Culture Media

Mouse Magnetic Luminex Assay
By Anonymous on 03/16/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 03/16/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 03/16/2018
Sample Tested: Serum

Mouse Magnetic Luminex Assay
By Anonymous on 03/16/2018
Sample Tested: Serum

Mouse Luminex® Discovery Assay
By Anonymous on 08/03/2017
Sample Tested: Serum

This multiplex kit worked well. The only thing I didn't like was the standards - apparently you REALLY need to mix them up like crazy before each dilution, and I guess I didn't mix enough, so my standards curve was not good.


Mouse Luminex® Discovery Assay
By Nagarjuna Cheemarla on 07/17/2017
Sample Tested: Lung single-cell suspension

Mouse Magnetic Luminex Assay
By Anonymous on 05/02/2016
Sample Tested: Cell culture supernatant,Cell Lysates,Tissue Lysates