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NK 252

Catalog #: 5293
1 Citation Datasheet / COA / SDS
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5293/10
5293/50
NK 252 | CAS No. 1414963-82-8 | Nrf2 Activators
1 Image
Description: Nrf2 activator

Chemical Name: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

NK 252 is an Nrf2 activator; interacts with the Nrf2-binding site of Keap1. Downregulates the expression of fibrogenic genes and increases antioxidant effects in NASH rat models of liver disease.

Technical Data

M.Wt:
285.26
Formula:
C13H11N5O3
Solubility:
Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1414963-82-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for NK 252

The citations listed below are publications that use Tocris products. Selected citations for NK 252 include:

1 Citation: Showing 1 - 1

  1. A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy.
    Authors: Vladimir Et al.
    Redox Biol  2021;48:102186

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