NPE-caged-proton
Chemical Name: 1-(2-Nitrophenyl)ethyl sulfate sodium salt
Purity: ≥98%
Biological Activity
NPE-caged-proton is a 1-(2-nitrophenyl)ethyl caged proton that releases a proton and a sulfate ion upon photolysis at 350 - 355 nm. Generates rapid acidifications (pH jumps) down to pH 2.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Characterization of a new caged proton capable of inducing large pH jumps.
Barth and Corrie
Biophys.J., 2002;83:2864 -
Kinetics of proton release after flash photolysis of 1-(2-Nitrophenyl)ethyl sulfate (caged sulfate) in aqueous solution.
Abbruzzetti et al.
J.Am.Chem.Soc., 2005;127:9865 -
Time-resolved infrared spectroscopy of pH-induced aggregation of the Alzheimer Aβ1-28 peptide.
Peralvarez-Marin et al.
J.Mol.Biol., 2008;379:589
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