Oxcarbazepine
Chemical Name: 10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide
Purity: ≥98%
Biological Activity
Oxcarbazepine is an anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action.
Schmutz et al.
Epilepsia, 1994;35:S47 -
Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures.
Zheng et al.
Epilepsia, 2009;50:83 -
Mechanism of action of carbamaz. and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.
Ambrosio et al.
Neurochem.Res., 2002;27:121
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