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Oxotremorine sesquifumarate

Catalog #: 0843
3 Citations Datasheet / COA / SDS
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0843/100
Oxotremorine sesquifumarate | CAS No. 17360-35-9 | Non-selective mAChR Agonists
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Description: Muscarinic agonist

Chemical Name: 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate

Purity: ≥98%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Oxotremorine sesquifumarate is a muscarinic agonist.

Technical Data

M.Wt:
380.4
Formula:
C12H18N2O.1.5C4H4O4
Solubility:
Soluble to 25 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
17360-35-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Differential stimulation in inositol phospholipid turnover in brain by analogs of oxotremorine.
    Fisher et al.
    J.Neurochem., 1984;43:1171
  3. Muscarinic receptor-mediated phosphoinositide hydrolysis in the rat retina.
    Moroi-Fetters et al.
    J.Pharmacol.Exp.Ther., 1988;246:553

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Citations for Oxotremorine sesquifumarate

The citations listed below are publications that use Tocris products. Selected citations for Oxotremorine sesquifumarate include:

3 Citations: Showing 1 - 3

  1. Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria.
    Authors: Bragança Et al.
    Front Pharmacol  2016;7:45
  2. Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium.
    Authors: Carneiro Et al.
    Br J Pharmacol  2014;171:3404
  3. Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors.
    Authors: Deng Et al.
    J Pharmacol Toxicol Methods  2013;68:323

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