Home / Dopamine D4 Receptor Antagonists / PD 168568 dihydrochloride

PD 168568 dihydrochloride

Catalog #: 3529
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3529/10
3529/50
PD 168568 dihydrochloride | CAS No. 1782532-06-2 | Dopamine D4 Receptor Antagonists
1 Image
Description: Potent and selective D4 antagonist

Chemical Name: 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

PD 168568 dihydrochloride is a potent and selective dopamine D4 receptor antagonist (Ki values are 8.8 and 1842 nM at D4 and D2 receptors respectively). Reverses amphetamine-stimulated locomotion in vivo and is orally active.

Technical Data

M.Wt:
422.39
Formula:
C22H27N3O.2HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1782532-06-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Isoindolinone enantiomers having affinity for the DA D4 receptor.
    Belliotti et al.
    Bioorg.Med.Chem.Lett., 1998;8:1499

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for PD 168568 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for PD 168568 dihydrochloride include:

1 Citation: Showing 1 - 1

  1. Intravitreally-administered DA D2-like (and D4), but not D1-like, receptor agonists reduce form-deprivation myopia in tree shrews.
    Authors: Ward Et al.
    Vis Neurosci  2017;34:E003

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PD 168568 dihydrochloride

There are currently no reviews for this product. Be the first to review PD 168568 dihydrochloride and earn rewards!

Have you used PD 168568 dihydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.