Home / Additional Synthetic Protease Inhibitors / Pepstatin A

Pepstatin A

Catalog #: 1190
3 Citations 1 Review Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1190/10
Pepstatin A
1 Image
Description: Selective and high affinity cathepsin D inhibitor

Purity: ≥95%

Product Details
Citations (3)
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Pepstatin A is an irreversible inhibitor of aspartic proteases. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with E 64d (Cat. No. 4545).

Technical Data

M.Wt:
685.91
Formula:
C34H63N5O9
Sequence:
VVXAX

(Modifications: Val-1 = N-terminal iso-Valeryl, X-3 = X-5 = Sta)

Solubility:
Soluble to 1 mg/ml in ethanol with gentle warming
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
26305-03-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Pepstatin A

The citations listed below are publications that use Tocris products. Selected citations for Pepstatin A include:

3 Citations: Showing 1 - 3

  1. Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation.
    Authors: Berg Et al.
    Cell Rep  2019;27:2837
  2. Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.
    Authors: Guerroue Et al.
    Mol Cell  2017;68:786
  3. WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinoma.
    Authors: Tsai Et al.
    J Neurosci  2013;4:e792

FAQs

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Reviews for Pepstatin A

Average Rating: 4 (Based on 1 Review)

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Protease Inhibitor
By Reetu Singh on 03/08/2021
Species: Human

use this as a protease inhibitor in my protein isolation buffer. It was a beneficial product for the Rat profiling cytokine assay kit.

Protease Inhibitor 1190
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