Home / Adrenergic alpha-1 Receptor Antagonists / Phentolamine Mesylate

Phentolamine Mesylate

Catalog #: 6431
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6431/100
Phentolamine Mesylate | CAS No. 65-28-1 | Adrenergic alpha-1 Receptor Antagonists
1 Image
Description: Adrenergic α receptor antagonist; antihypertensive

Chemical Name: 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol methanesulfonate

Purity: ≥98%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Phentolamine Mesylate is a non-selective adrenergic α receptor antagonist (pKB = 8.07). Intravenous injection causes hypotension and tachycardia in rats. Intraperitoneal injection in mice increases plasma FGF21 levels.

Technical Data

M.Wt:
377.46
Formula:
C17H19N3O.CH4O3S
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
65-28-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Phentolamine Mesylate

The citations listed below are publications that use Tocris products. Selected citations for Phentolamine Mesylate include:

2 Citations: Showing 1 - 2

  1. Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors.
    Authors: Kira E Et al.
    Cell Rep  2022;40:111426
  2. Propranolol Sensitizes Vascular Sarcoma Cells to Doxorubicin by Altering Lysosomal Drug Sequestration and Drug Efflux.
    Authors: David R Et al.
    Front Oncol  2021;10:614288

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Phentolamine Mesylate

There are currently no reviews for this product. Be the first to review Phentolamine Mesylate and earn rewards!

Have you used Phentolamine Mesylate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.