Prostaglandin E2 Parameter Assay Kit Summary
Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 40 | 40 | 40 |
Mean (pg/mL) | 234 | 895 | 1456 | 253 | 835 | 1331 |
Standard Deviation | 21 | 45 | 89 | 33 | 82 | 120 |
CV% | 9 | 5 | 6.1 | 12.9 | 9.9 | 9 |
Recovery
The recovery of PGE2 spiked to levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=4) | 97 | 84-106 |
EDTA Plasma (n=4) | 93 | 82-108 |
Heparin Plasma (n=4) | 94 | 81-111 |
Serum (n=4) | 97 | 86-114 |
Urine (n=4) | 99 | 81-111 |
Linearity
Scientific Data
Preparation and Storage
Background: Prostaglandin E2/PGE2
Prostaglandin E2 (PGE2) is formed in a variety of cells from prostaglandin H2, which is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGE2 has a number of biological actions, including vasodilation, both anti- and proinflammatory action, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.
Citations for Prostaglandin E2 Parameter Assay Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Geniposidic acid alleviates osteoarthritis progression through inhibiting inflammation and chondrocytes ferroptosis
Authors: Sun, J;Song, X;Wang, C;Ruan, Q;
Journal of cellular and molecular medicine
Species: Murine polyomavirus strain A3
Sample Types: Cell Culture Supernates
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Protective effect of sucrose esters from cape gooseberry (Physalis peruviana L.) in TNBS-induced colitis
Authors: Ocampo, YC;Castro, JP;Pájaro, IB;Caro, D;Talero, E;Motilva, V;Franco, LA;
PloS one
Species: Murine polyomavirus strain A3
Sample Types: Cell Culture Supernates
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Evaluating the Anti-Osteoarthritis Potential of Standardized Boswellia serrata Gum Resin Extract in Alleviating Knee Joint Pathology and Inflammation in Osteoarthritis-Induced Models
Authors: Choi, YJ;Jung, JI;Bae, J;Lee, JK;Kim, EJ;
International journal of molecular sciences
Species: S. agalactiae
Sample Types: Serum
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Nicotinamide Riboside Augments Human Macrophage Migration via SIRT3-Mediated Prostaglandin E2 Signaling
Authors: Wu, J;Bley, M;Steans, RS;Meadows, AM;Huffstutler, RD;Tian, R;Griffin, JL;Sack, MN;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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Chronic Treatment with Nigella sativa Oil Exerts Antimanic Properties and Reduces Brain Inflammation in Rats
Authors: Uzzan, S;Rostevanov, IS;Rubin, E;Benguigui, O;Marazka, S;Kaplanski, J;Agbaria, R;Azab, AN;
International journal of molecular sciences
Species: S. agalactiae
Sample Types: Tissue Homogenates
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Immunomodulatory performance of GMP-compliant, clinical-grade mesenchymal stromal cells from four different sources
Authors: Arki, MK;Moeinabadi-Bidgoli, K;Niknam, B;Mohammadi, P;Hassan, M;Hossein-Khannazer, N;Vosough, M;
Heliyon
Species: Human hepegivirus
Sample Types: Cell Culture Supernates
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Anti-inflammatory of disenecionyl cis-khellactone in LPS-stimulated RAW264.7 cells and the its inhibitory activity on soluble epoxide hydrolase
Authors: Park, JH;Kim, JH;Jang, SI;Cho, BO;
Heliyon
Species: Mouse
Sample Types: Cell Culture Supernates
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Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-?B axis and ameliorates osteoarthritis in mice
Authors: Zhang, P;Jin, Y;Xia, W;Wang, X;Zhou, Z;
Journal of orthopaedic translation
Species: Mouse
Sample Types: Cell Culture Supernates
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Protective Effects of Cirsilineol against Lipopolysaccharide-Induced Inflammation; Insights into HO-1, COX-2, and iNOS Modulation
Authors: Kim, GO;Park, DH;Bae, JS;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Ergothioneine inhibits the progression of osteoarthritis via the Sirt6/NF-?B axis both in vitro and in vivo
Authors: Wang, Z;Ma, J;Miao, Z;Sun, Y;Dong, M;Lin, Y;Wu, Y;Sun, Z;
International immunopharmacology
Species: Rat
Sample Types: Cell Culture Supernates
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Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction
Authors: HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo
PLoS ONE, 2023-04-20;18(4):e0281834.
Species: Human
Sample Types: Cell Culture Supernates
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Anti-Neuroinflammatory and Neuroprotective Effect of Intermedin B Isolated from the Curcuma longa L. via NF-kappaB and ROS Inhibition in BV2 Microglia and HT22 Hippocampal Cells
Authors: H Lee, Z Liu, L Dong, DY Lee, D Yoon, H Oh, YC Kim, RB An, DS Lee
International Journal of Molecular Sciences, 2023-04-17;24(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Structural Characterization and Anti-Inflammatory Effects of 24-Methylcholesta-5(6), 22-Diene-3beta-ol from the Cultured Marine Diatom Phaeodactylum tricornutum; Attenuate Inflammatory Signaling Pathways
Authors: KW Samarakoon, AI Kuruppu, JY Ko, JH Lee, YJ Jeon
Marine Drugs, 2023-04-03;21(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Syringaresinol attenuates osteoarthritis via regulating the NF-kappaB pathway
Authors: X Wang, D Wang, B Deng, L Yan
International immunopharmacology, 2023-03-28;118(0):109982.
Species: Mouse
Sample Types: Cell Culture Supernates
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Basic Properties of Adipose-Derived Mesenchymal Stem Cells of Rheumatoid Arthritis and Osteoarthritis Patients
Authors: E Kuca-Warna, W Kurowska, M Pleba?czyk, A Wajda, A Kornatka, T Burakowski, I Janicka, P Syrówka, U Skalska
Pharmaceutics, 2023-03-20;15(3):.
Species: Human
Sample Types: Cell Culture Supernates
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Anti-inflammatory effects of Peucedanum japonicum Thunberg leaves extract in Lipopolysaccharide-stimulated RAW264.7�cells
Authors: JH Park, JH Kim, JY Shin, ES Kang, BO Cho
Journal of ethnopharmacology, 2023-03-10;309(0):116362.
Species: Mouse
Sample Types: Cell Lysate
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Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells
Authors: EA Ross, LA Turner, H Donnelly, A Saeed, MP Tsimbouri, KV Burgess, G Blackburn, V Jayawarna, Y Xiao, MAG Oliva, J Willis, J Bansal, P Reynolds, JA Wells, J Mountford, M Vassalli, N Gadegaard, ROC Oreffo, M Salmeron-S, MJ Dalby
Nature Communications, 2023-02-10;14(1):753.
Species: Human
Sample Types: Cell Culture Supernates
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Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction
Authors: HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo
PLoS ONE, 2023;18(4):e0281834.
Species: Human
Sample Types: Cell Culture Supernates
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Plantamajoside suppresses the activation of NF-kappaB and MAPK and ameliorates the development of osteoarthritis
Authors: S Lin, J Lu, Q Chen, H Jiang, C Lou, C Lin, W Wang, J Lin, X Pan, X Xue
International immunopharmacology, 2022-12-28;115(0):109582.
Species: Mouse
Sample Types: Cell Culture Supernates
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Potential Anti-Inflammatory and Chondroprotective Effect of Luzula sylvatica
Authors: J Cholet, C Decombat, L Delort, M Gainche, A Berry, C Ogeron, I Ripoche, M Vareille-D, M Vermerie, D Fraisse, C Felgines, A Rossary, E Ranouille, JY Berthon, A Tourrette, J Priam, E Saunier, Y Troin, F Senejoux, P Chalard, F Caldefie-C
International Journal of Molecular Sciences, 2022-12-21;24(1):.
Species: Human
Sample Types: Plasma
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Effects of Thymoquinone Alone or in Combination with Losartan on the Cardiotoxicity Caused by Oxidative Stress and Inflammation in Hypercholesterolemia
Authors: ZH Al-Oanzi, FO Alenazy, HH Alhassan, MR El-Aassar, AI Alzarea, SI Alzarea, AM Abbas, MH Alanazi, MM Al-Enazi
Journal of cardiovascular development and disease, 2022-12-01;9(12):.
Species: Rat
Sample Types: Serum
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Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia
Authors: EL Ngu, CY Tan, NJ Lai, KH Wong, SH Lim, LC Ming, KO Tan, SM Phang, YY Yow
Metabolites, 2022-11-20;12(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-kappaB pathway
Authors: J Wu, H Li, F Hu, P Luo
Journal of Orthopaedic Translation, 2022-11-15;38(0):190-202.
Species: Mouse
Sample Types: Cell Culture Supernates
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Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-kappaB and MAPK Pathways in LPS-Stimulated BV-2 Microglia
Authors: B Li, M Wang, S Chen, M Li, J Zeng, S Wu, Y Tu, Y Li, R Zhang, F Huang, X Tong
BioMed Research International, 2022-11-09;2022(0):3263446.
Species: Mouse
Sample Types: Cell Culture Supernates
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Bioreactor Expansion Reconfigures Metabolism and Extracellular Vesicle Biogenesis of Human Adipose-derived Stem Cells In Vitro
Authors: R Jeske, X Chen, S Ma, EZ Zeng, T Driscoll, Y Li
Biochemical engineering journal, 2022-11-02;188(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Formononetin inhibits IL-1beta-induced inflammation in human chondrocytes and slows the progression of osteoarthritis in rat model via the regulation of PTEN/AKT/NF-kappaB pathway
Authors: C Jia, F Hu, D Lu, H Jin, H Lu, E Xue, D Wu
International immunopharmacology, 2022-10-25;113(0):109309.
Species: Human, Rat
Sample Types: Cell Culture Supernates
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COX-2/PGE2/VEGF signaling promotes ERK-mediated BMSCs osteogenic differentiation under hypoxia by the paracrine action of ECs
Authors: Y Wu, M Liu, H Zhou, X He, W Shi, Q Yuan, Y Zuo, B Li, Q Hu, Y Xie
Cytokine, 2022-10-07;161(0):156058.
Species: Rat
Sample Types: Cell Culture Supernates
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Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under in-vitro conditions
Authors: A Hasan, S Devi Ms, G Sharma, V Narayanan, P Sathiyaraj, S Vinayak, S Sunil
Journal of ethnopharmacology, 2022-09-29;0(0):115762.
Species: Mouse
Sample Types: Cell Culture Supernates
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Correlations between Cytokine Levels, Liver Function Markers, and Neuropilin-1 Expression in Patients with COVID-19
Authors: SA El Kazafy, YM Fouad, AF Said, HH Assal, TM Ali, AE Ahmed, BH Elesawy, OM Ahmed
Vaccines, 2022-09-29;10(10):.
Species: Human
Sample Types: Serum
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Knockdown of LMX1B Suppressed Cell Apoptosis and Inflammatory Response in IL-1beta-Induced Human Osteoarthritis Chondrocytes through NF-kappaB and NLRP3 Signal Pathway
Authors: Y Mu, L Wang, L Fu, Q Li
Mediators of Inflammation, 2022-09-12;2022(0):1870579.
Species: Human
Sample Types: Cell Culture Supernates
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Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE2 Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4
Authors: GA Estúa-Acos, B Buentello-, FS Magaña-Gue, JE Flores, O Vivanco-Ro, I Castro-Sal, K Zarco-Ávil, MA García-Mej, Y Garfias
Cells, 2022-09-10;11(18):.
Species: Human
Sample Types: Cell Culture Supernates
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Human Adipose Mesenchymal Stromal/Stem Cells Improve Fat Transplantation Performance
Authors: MS Piccinno, T Petrachi, M Pignatti, A Murgia, G Grisendi, O Candini, E Resca, V Bergamini, F Ganzerli, A Portone, I Mastrolia, C Chiavelli, I Castelli, D Bernabei, M Tagliazucc, E Bonetti, F Lolli, G De Santis, M Dominici, E Veronesi
Cells, 2022-09-07;11(18):.
Species: Xenograft
Sample Types: Serum
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Anti-Inflammatory Effect of Sparstolonin B through Inhibiting Expression of NF-kappaB and STAT-1
Authors: N Kim, C Kim, SH Ryu, GO Kim, JS Bae
International Journal of Molecular Sciences, 2022-09-06;23(18):.
Species: Human
Sample Types: Cell Culture Supernates
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Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis
Authors: Q Sun, Y Zhang, Y Ding, W Xie, H Li, S Li, Y Li, M Cai
Cells, 2022-09-05;11(17):.
Species: Mouse
Sample Types: Serum
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Ocular microbiota promotes pathological angiogenesis and inflammation in sterile injury-driven corneal neovascularization
Authors: HJ Lee, CH Yoon, HJ Kim, JH Ko, JS Ryu, DH Jo, JH Kim, D Kim, JY Oh
Mucosal Immunology, 2022-08-19;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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A Nested Case-Control Study of the Relationship between Salivary Inflammatory Mediators, Periodontal Parameters, and Preterm Birth in a Chinese Population
Authors: M Wu, C Ye, H Li, X Yang, S Zhu, F Zhou, Y Hao, S Chen, S Jiang
BioMed Research International, 2022-08-18;2022(0):8629680.
Species: Human
Sample Types: Saliva
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Association of the Heart Rate Variability Response to Active Standing with the Severity of Calcific Aortic Valve Disease: Novel Insights of a Neurocardiovascular Pathology
Authors: J Rodríguez-, JM Torres-Are, N Ávila-Vanz, R Springall, R Bojalil, O Infante, C Lerma, JC Echeverría
Journal of Clinical Medicine, 2022-08-16;11(16):.
Species: Human
Sample Types: Serum
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Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-kappaB Pathway
Authors: S Li, Y Shi, S Zhang, H Li, Z Ye, J Kong, W Hong, Y Tu, J Ren, Z Meftah, C Xie, X Wang, X Zhang
Oxidative Medicine and Cellular Longevity, 2022-07-28;2022(0):2188145.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-Inflammatory Effects of Phlebia sp. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages
Authors: EH Lim, SK Mun, JJ Kim, DJ Chang, ST Yee
BioMed Research International, 2022-07-14;2022(0):2717196.
Species: Mouse
Sample Types: Cell Culture Supernates
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IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function
Authors: ME Kotas, CM Moore, JG Gurrola, SD Pletcher, AN Goldberg, R Alvarez, S Yamato, PE Bratcher, CA Shaughness, PL Zeitlin, IH Zhang, Y Li, MT Montgomery, K Lee, EK Cope, RM Locksley, MA Seibold, ED Gordon
JCI Insight, 2022-07-08;7(13):.
Species: Mouse
Sample Types: Tissue Homogenates
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15-PGDH regulates hematopoietic and gastrointestinal fitness during aging
Authors: WJ Ho, JNP Smith, YS Park, M Hadiono, K Christo, A Jogasuria, Y Zhang, AV Broncano, L Kasturi, DM Dawson, SL Gerson, SD Markowitz, AB Desai
PLoS ONE, 2022-05-19;17(5):e0268787.
Species: Mouse
Sample Types: Tissue Homogenates
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Molecular and Biochemical Mechanism of Cannabidiol in the Management of the Inflammatory and Oxidative Processes Associated with Endometriosis
Authors: T Genovese, M Cordaro, R Siracusa, D Impellizze, S Caudullo, E Raffone, F Macrí, L Interdonat, E Gugliandol, C Interlandi, R Crupi, R D'Amico, R Fusco, S Cuzzocrea, R Di Paola
International Journal of Molecular Sciences, 2022-05-12;23(10):.
Species: Rat
Sample Types: Peritoneal Fluid
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Effect of Manual Therapy Compared to Ibuprofen on Primary Dysmenorrhea in Young Women-Concentration Assessment of C-Reactive Protein, Vascular Endothelial Growth Factor, Prostaglandins and Sex Hormones
Authors: Z Barcikowsk, ME Grzybowska, P W??, M Jaskulak, M Kurpas, M Sotomski, M Starzec-Pr, E Rajkowska-, R Hansdorfer, K Zorena
Journal of Clinical Medicine, 2022-05-10;11(10):.
Species: Human
Sample Types: Serum
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Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions
Authors: R Boi, K Ebefors, M Henricsson, J Borén, J Nyström
Scientific Reports, 2022-05-05;12(1):7322.
Species: Human
Sample Types: Cell Culture Supernates
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Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression
Authors: J Zhang, H Zhang, X Ding, J Hu, Y Li, J Zhang, H Wang, S Qi, A Xie, J Shi, M Xiang, Y Bin, G Wang, L Wang, Z Wang
Theranostics, 2022-05-01;12(8):3776-3793.
Species: Human
Sample Types: Serum
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Resveratrol Inhibition of the WNT/beta-Catenin Pathway following Discogenic Low Back Pain
Authors: T Genovese, D Impellizze, R D'Amico, M Cordaro, AF Peritore, R Crupi, E Gugliandol, S Cuzzocrea, R Fusco, R Siracusa, R Di Paola
International Journal of Molecular Sciences, 2022-04-07;23(8):.
Species: Human
Sample Types: Tissue Homogenates
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Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs
Authors: P Arora, W Li, X Huang, W Yu, R Huang, Q Jiang, C Chen
International Journal of Molecular Sciences, 2022-04-06;23(7):.
Species: Human
Sample Types: Cell Culture Supernates
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Mechanism of Traditional Tibetan Medicine Grubthobrildkr Alleviated Gastric Ulcer Induced by Acute Systemic Hypoxia in Rats
Authors: M Yang, Z Yang, Y Li, S Su, Z Li, D Lu
BioMed Research International, 2022-04-05;2022(0):4803956.
Species: Rat
Sample Types: Serum
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Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation
Authors: Q Zhao, W Dai, HY Chen, RE Jacobs, BV Zlokovic, BT Lund, A Montagne, A Bonnin
Proceedings of the National Academy of Sciences of the United States of America, 2022-04-04;119(15):e2113310119.
Species: Mouse
Sample Types: Tissue Lysates
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Immune-enhancing effect of water-soluble beta-glucan derived from enzymatic hydrolysis of yeast glucan
Authors: Y Xin, H Ji, E Cho, KB Roh, J You, D Park, E Jung
Biochemistry and Biophysics Reports, 2022-03-27;30(0):101256.
Species: Mouse
Sample Types: Cell Culture Supernates
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Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis?fibroblast?like synoviocytes by inhibiting the NF?kappaB and MAPK signaling pathways
Authors: X Gao, X Kang, H Lu, E Xue, R Chen, J Pan, J Ma
Molecular Medicine Reports, 2022-03-24;25(5):.
Species: Rat
Sample Types: Serum
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Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKalpha/beta-NF-kappaB and Keap1-Nrf2 Signalling Pathways
Authors: Y Yuan, Q Hu, L Liu, F Xie, L Yang, Y Li, C Zhang, H Chen, J Tang, X Shen
Frontiers in Pharmacology, 2022-03-07;13(0):817596.
Species: Mouse
Sample Types: Cell Culture Supernates
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HucMSCs-exosomes containing miR-21 promoted estrogen production in ovarian granulosa cells via LATS1-mediated phosphorylation of LOXL2 and YAP
Authors: JH Cai, YT Sun, S Bao
General and comparative endocrinology, 2022-03-07;0(0):114015.
Species: Human
Sample Types: Cell Culture Supernates
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Imbalances in TCA, Short Fatty Acids and One-Carbon Metabolisms as Important Features of Homeostatic Disruption Evidenced by a Multi-Omics Integrative Approach of LPS-Induced Chronic Inflammation in Male Wistar Rats
Authors: J Hernandez-, N Abasolo, H Palacios-J, E Foguet-Rom, D Suñol, M Galofré, A Caimari, L Baselga-Es, JM Del Bas, M Mulero
International Journal of Molecular Sciences, 2022-02-25;23(5):.
Species: Rat
Sample Types: Plasma
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Neuron-Microglia Contacts Govern the PGE2 Tolerance through TLR4-Mediated de Novo Protein Synthesis
Authors: HC Kuo, KF Lee, SL Chen, SC Chiu, LY Lee, WP Chen, CC Chen, CH Chu
Biomedicines, 2022-02-10;10(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Luteolin Protects Chondrocytes from H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling
Authors: Z Zhou, L Zhang, Y Liu, C Huang, W Xia, H Zhou, Z Zhou, X Zhou
Oxidative Medicine and Cellular Longevity, 2022-02-01;2022(0):5635797.
Species: Mouse
Sample Types: Cell Culture Supernates
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Impact and Possible Mechanism(s) of Adipose Tissue-Derived Mesenchymal Stem Cells on T-Cell Proliferation in Patients With Rheumatic Disease
Authors: E Kuca-Warna, M Olesi?ska, P Szcz?sny, E Kontny
Frontiers in Physiology, 2022-01-13;12(0):749481.
Species: Human
Sample Types: Cell Culture Supernates
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Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties
Authors: A Gallo, N Cuscino, F Contino, M Bulati, M Pampalone, G Amico, G Zito, C Carcione, C Centi, A Bertani, PG Conaldi, V Miceli
International Journal of Molecular Sciences, 2022-01-13;23(2):.
Species: Human
Sample Types: Cell Culture Supernates
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The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain
Authors: D Lee, H Jo, C Go, Y Jang, N Chu, S Bae, D Kang, Y Kim, JS Kang
International Journal of Molecular Sciences, 2022-01-11;23(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model
Authors: JJ Tang, LF Huang, JL Deng, YM Wang, C Guo, XN Peng, Z Liu, JM Gao
Redox Biology, 2022-01-08;50(0):102229.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds
Authors: SW Shin, YS Hwang
Nutrients, 2021-12-28;14(1):.
Species: Human
Sample Types: Cell Culture Supernates
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GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by P. gingivalis LPS and Concurrent Compression
Authors: A Stemmler, J Symmank, J Steinmetz, K von Brande, CL Hennig, C Jacobs
International Journal of Molecular Sciences, 2021-12-19;22(24):.
Species: Human
Sample Types: Cell Culture Supernates
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Dracocephalum moldavica Ethanol Extract Suppresses LPS-Induced Inflammatory Responses through Inhibition of the JNK/ERK/NF-kappaB Signaling Pathway and IL-6 Production in RAW 264.7 Macrophages and in Endotoxic-Treated Mice
Authors: KM Kim, SY Kim, TJ Mony, HJ Bae, SD Han, ES Lee, SH Choi, SH Hong, SD Lee, SJ Park
Nutrients, 2021-12-16;13(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD2 and DP1 receptor in acute respiratory distress syndrome
Authors: X Hu, YA Zhang, B Chen, Z Jin, ML Lin, M Li, HX Mei, JC Lu, YQ Gong, SW Jin, SX Zheng
International immunopharmacology, 2021-11-10;102(0):108348.
Species: Rat
Sample Types: Cell Lysates
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High-Molecular-Weight Hyaluronic Acid Inhibits IL-1beta-Induced Synovial Inflammation and Macrophage Polarization through the GRP78-NF-kappaB Signaling Pathway
Authors: CH Lee, CF Chiang, FC Kuo, SC Su, CL Huang, JS Liu, CH Lu, CH Hsieh, CC Wang, CH Lee, PH Shen
International Journal of Molecular Sciences, 2021-11-03;22(21):.
Species: Human
Sample Types: Cell Culture Supernates
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Safety and Efficacy of Combined Low-Dose Lithium and Low-Dose Aspirin: A Pharmacological and Behavioral Proof-of-Concept Study in Rats
Authors: R Shvartsur, G Agam, A Shnaider, S Uzzan, A Nassar, A Jabarin, N Abu-Freha, K Meir, AN Azab
Pharmaceutics, 2021-11-01;13(11):.
Species: Rat
Sample Types: Tissue Homogenates
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beta2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME
Authors: H Mohammadpo, CR MacDonald, PL McCarthy, SI Abrams, EA Repasky
Cell Reports, 2021-10-26;37(4):109883.
Species: Human, Mouse
Sample Types: Cell Lysates
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Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium
Authors: MR Shin, JH Lee, JA Lee, MJ Kim, HJ Park, BW Park, SB Seo, SS Roh
BMC complementary medicine and therapies, 2021-10-26;21(1):269.
Species: Human
Sample Types: Cell Culture Supernates
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Clinical and Correlated Responses among Steroid Hormones and Oxidant/Antioxidant Biomarkers in Pregnant, Non-Pregnant and Lactating CIDR-Pre-Synchronized Dromedaries (Camelus dromedarius)
Authors: RH Mohamed, A Khalphalla, K Nakada, E Elmeligy, D Hassan, EA Ebissy, RA Ghandour, SA Mousa, ASA Hassaneen
Veterinary sciences, 2021-10-21;8(11):.
Species: Camel
Sample Types: Serum
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Rapamycin-loaded Poly(lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection
Authors: E Pape, M Parent, A Pinzano, A Sapin-Mine, C Henrionnet, P Gillet, J Scala-Bert, N Gambier
International journal of pharmaceutics, 2021-10-16;609(0):121198.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory Effect of 4,5-Dicaffeoylquinic Acid on RAW264.7 Cells and a Rat Model of Inflammation
Authors: G Jang, S Lee, J Hong, B Park, D Kim, C Kim
Nutrients, 2021-10-09;13(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease
Authors: L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen
Brain, Behavior, and Immunity, 2021-09-06;98(0):337-348.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms
Authors: J Cheng, Z Xie, S Wang, S Wen, S Niu, C Shi, L Yu, X Xu
BMC pulmonary medicine, 2021-09-06;21(1):284.
Species: Human
Sample Types: Sputum Supernates
-
Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen alpha receptor in female db/db mice
Authors: JJ Shi, HF Liu, T Hu, X Gao, YB Zhang, WR Li, Q Wang, SJ Zhang, D Tang, YB Chen
Journal of ethnopharmacology, 2021-08-23;281(0):114562.
Species: Mouse
Sample Types: Tissue Homogenates
-
TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration
Authors: S Liu, Q Wang, Z Li, L Ma, T Li, Y Li, N Wang, C Liu, P Xue, C Wang
Oxidative Medicine and Cellular Longevity, 2021-08-21;2021(0):9965737.
Species: Mouse
Sample Types: Tissue Homogenates
-
CCNB2/SASP/Cathepsin B & PGE2 Axis Induce Cell Senescence Mediated Malignant Transformation
Authors: Y Wang, H Zhang, M Wang, J He, H Guo, L Li, J Wang
International journal of biological sciences, 2021-08-13;17(13):3538-3553.
Species: Human
Sample Types: Cell Culture Supernates
-
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-kappaB/MAPK pathways
Authors: JJ Tang, MR Wang, S Dong, LF Huang, QR He, JM Gao
European Journal of Medicinal Chemistry, 2021-07-21;224(0):113713.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-Neuroinflammatory and Anti-Inflammatory Activities of Phenylheptatriyne Isolated from the Flowers of Coreopsis lanceolata L. via NF-kappaB Inhibition and HO-1 Expression in BV2 and RAW264.7 Cells
Authors: H Lee, Z Liu, CS Yoon, L Dong, W Ko, ER Woo, DS Lee
International Journal of Molecular Sciences, 2021-07-13;22(14):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Recombinant platelet-derived growth factor-BB alleviates osteoarthritis in a rat model by decreasing chondrocyte apoptosis in vitro and in vivo
Authors: P Zhu, Z Wang, Z Sun, B Liao, Y Cai
Journal of Cellular and Molecular Medicine, 2021-07-11;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway
Authors: HJ Kim, YJ Kim, W Park
Scientific Reports, 2021-05-28;11(1):11298.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti?inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in�lipopolysaccharide?stimulated RAW264.7 macrophages
Authors: BO Cho, JY Shin, HJ Kang, JH Park, S Hao, F Wang, SI Jang
Molecular Medicine Reports, 2021-05-26;24(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
Authors: K Battiston, I Parrag, M Statham, D Louka, H Fischer, G Mackey, A Daley, F Gu, E Baldwin, B Yang, B Muirhead, EA Hicks, H Sheardown, L Kalachev, C Crean, J Edelman, JP Santerre, W Naimark
Nature Communications, 2021-05-17;12(1):2875.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of Lipopolysaccharide-Induced Inflammatory and Oxidative Responses by Trans-cinnamaldehyde in C2C12 Myoblasts
Authors: C Park, H Lee, S Hong, IMN Molagoda, JW Jeong, CY Jin, GY Kim, SH Choi, SH Hong, YH Choi
International Journal of Medical Sciences, 2021-04-23;18(12):2480-2492.
Species: Human
Sample Types: Cell Culture Supernates
-
Cyclic mechanical stimulation inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation via cell cycle arrest
Authors: Y Yan, H Zou, X Lian, L Yang
Journal of biomechanics, 2021-04-08;121(0):110424.
Species: Human
Sample Types: Cell Culture Supernates
-
Stereochemical Determination of Fistularins Isolated from the Marine Sponge Ecionemia acervus and Their Regulatory Effect on Intestinal Inflammation
Authors: YK Ji, SM Lee, NH Kim, NV Tu, YN Kim, JD Heo, EJ Jeong, JR Rho
Marine Drugs, 2021-03-22;19(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
COX2 regulates senescence secretome composition and senescence surveillance through PGE2
Authors: S Gonçalves, K Yin, Y Ito, A Chan, I Olan, S Gough, L Cassidy, E Serrao, S Smith, A Young, M Narita, M Hoare
Cell Reports, 2021-03-16;34(11):108860.
Species: Human
Sample Types: Cell Culture Supernates
-
Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model
Authors: E Park, CG Lee, SJ Han, SH Yun, S Hwang, H Jeon, J Kim, CW Choi, S Yang, SY Jeong
International Journal of Molecular Sciences, 2021-03-15;22(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model
Authors: L Bertoni, S Jacquet-Gu, T Branly, M Desancé, F Legendre, M Melin, P Rivory, DJ Hartmann, A Schmutz, JM Denoix, M Demoor, F Audigié, P Galéra
International Journal of Molecular Sciences, 2021-03-02;22(5):.
Species: Equine
Sample Types: Synovial Fluid
-
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
Nature Communications, 2021-02-22;12(1):1209.
Species: Human
Sample Types: Cell Culture Supernates
-
Extracorporeal shock wave therapy for treating primary dysmenorrhea: A randomized controlled trial
Authors: R Xing, J Yang, R Wang, Y Wang
Medicine, 2021-02-05;100(5):e23798.
Species: Human
Sample Types: Plasma
-
Isoquinolinequinone Derivatives from a Marine Sponge (Haliclona sp.) Regulate Inflammation in In Vitro System of Intestine
Authors: YN Kim, YK Ji, NH Kim, N Van Tu, JR Rho, EJ Jeong
Marine Drugs, 2021-02-04;19(2):.
Species: Human
Sample Types: Cell Culture Supernates
-
Nutrients Bioaccessibility and Anti-inflammatory Features of Fermented Bee Pollen: A Comprehensive Investigation
Authors: P Filannino, R Di Cagno, O Vincentini, D Pinto, A Polo, F Maialetti, A Porrelli, M Gobbetti
Frontiers in Microbiology, 2021-02-02;12(0):622091.
Species: Human
Sample Types: Cell Culture Supernates
-
Agitation in a Microcarrier-based Spinner Flask Bioreactor Modulates Homeostasis of Human Mesenchymal Stem Cells
Authors: R Jeske, S Lewis, AC Tsai, K Sanders, C Liu, X Yuan, Y Li
Biochemical engineering journal, 2021-01-27;168(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
DHA attenuated Japanese Encephalitis virus infection-induced neuroinflammation and neuronal cell death in cultured rat Neuron/glia
Authors: CY Chang, CC Wu, JD Wang, JR Li, YY Wang, SY Lin, WY Chen, SL Liao, CJ Chen
Brain, Behavior, and Immunity, 2021-01-21;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
NSAIDs inhibit bone healing through the downregulation of TGF-&beta3 expression during endochondral ossification
Authors: I Pountos, M Panteli, G Walters, PV Giannoudis
Injury, 2021-01-10;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition effect of Caragana sinica root extracts on Osteoarthritis through MAPKs, NF-&kappaB signaling pathway
Authors: GY Min, JM Park, IH Joo, DH Kim
International Journal of Medical Sciences, 2021-01-01;18(4):861-872.
Species: Rat
Sample Types: Serum
-
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Authors: A Dorronsoro, V Lang, I Ferrin, J Fernández-, L Zabaleta, E Pérez-Ruiz, P Sepúlveda, C Trigueros
Scientific Reports, 2020-12-14;10(1):21853.
Species: Human
Sample Types: Cell Culture Supernates
-
Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors
Authors: MFA Mohamed, AA Marzouk, A Nafady, DA El-Gamal, RM Allam, GEA Abuo-Rahma, HI El Subbagh, AH Moustafa
Bioorg Chem, 2020-10-28;105(0):104439.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
Authors: L Jia, K Xue, J Liu, OA Habotta, L Hu, AE Abdel Mone
Mediators Inflamm, 2020-09-29;2020(0):9419085.
Species: Rat
Sample Types: Cell Culture Supernates
-
Nano wet milled celecoxib extended release microparticles for local management of chronic inflammation
Authors: C Salgado, L Guénée, R ?erný, E Allémann, O Jordan
Int J Pharm, 2020-08-19;589(0):119783.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay -
Allogeneic synovial membrane-derived mesenchymal stem cells do not significantly affect initial inflammatory parameters in a LPS-induced acute synovitis model
Authors: G Rosa, AMT Krieck, E Padula, JPH Pfeifer, JB de Souza, M Rossi, F Stievani, E Deffune, R Takahira, ALG Alves
Res. Vet. Sci., 2020-08-08;132(0):485-491.
Species: Equine
Sample Types: Synovial Fluid
-
Anti-Inflammatory and Antioxidant Effects of Carpesium cernuum L. Methanolic Extract in LPS-Stimulated RAW 264.7 Macrophages
Authors: YJ Park, SY Cheon, DS Lee, DC Cominguez, Z Zhang, S Lee, HJ An
Mediators Inflamm., 2020-08-07;2020(0):3164239.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-kappaB and PI3K-Akt signaling networks
Authors: MA Haque, I Jantan, H Harikrishn, W Ahmad
BMC Complement Med Ther, 2020-08-06;20(1):245.
Species: Human, Tinospora crispa
Sample Types: Cell Culture Supernates
-
Silver nanoparticle-activated COX2/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo
Authors: B Chen, Q Chai, S Xu, Q Li, T Wu, S Chen, L Wu
Ecotoxicol. Environ. Saf., 2020-08-04;204(0):111070.
Species: Human
Sample Types: Cell Culture Supernates
-
7-Acetoxycoumarin Inhibits LPS-Induced Inflammatory Cytokine Synthesis by I&kappaB&alpha Degradation and MAPK Activation in Macrophage Cells
Authors: T Park, JS Park, JH Sim, SY Kim
Molecules, 2020-07-08;25(14):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of UVB-Induced Inflammation by Laminaria japonica Extract via Regulation of nc886-PKR Pathway
Authors: KS Lee, E Cho, JB Weon, D Park, M Fréchet, H Chajra, E Jung
Nutrients, 2020-06-30;12(7):.
Species: Human
Sample Types: Cell Culture Supernates
-
Immunomodulation by an Omega-6 Fatty Acid Reduced Mixed Lipid Emulsion in Murine Acute Respiratory Distress Syndrome
Authors: M Hecker, M Rose, A Hecker, H Dietrich, MB Schaefer, N Sommer, W Seeger, K Mayer
J Clin Med, 2020-06-29;9(7):.
Species: Mouse
Sample Types: BALF
-
An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization
Authors: L Bertoni, S Jacquet-Gu, T Branly, F Legendre, M Desancé, C Mespoulhes, M Melin, DJ Hartmann, A Schmutz, JM Denoix, P Galéra, M Demoor, F Audigié
PLoS ONE, 2020-06-25;15(6):e0235251.
Species: Equine
Sample Types: Synovial Fluid
-
Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells
Authors: A Allen, N Vaninov, M Li, S Nguyen, P Igo, AW Tilles, B O'Rourke, BLK Miller, B Parekkadan, RN Barcia
Sci Rep, 2020-06-23;10(1):10142.
Species: Human
Sample Types: Cell Culture Supernates
-
Nomilin targets the Keap1-Nrf2 signalling and ameliorates the development of osteoarthritis
Authors: XH Xue, JX Xue, W Hu, FL Shi, Y Yang
J. Cell. Mol. Med., 2020-06-21;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti?inflammatory activity of 3,5,6,7,3',4'?hexamethoxyflavone via repression of the NF?&kappaB and MAPK signaling pathways in LPS?stimulated RAW264.7 cells
Authors: ES Son, JW Park, SH Kim, HR Park, W Han, OC Kwon, JY Nam, SH Jeong, CS Lee
Mol Med Rep, 2020-06-18;22(3):1985-1993.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation
Authors: HJ Lee, JH Ko, HJ Kim, HJ Jeong, JY Oh
JCI Insight, 2020-06-18;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway
Authors: P Zhu, H Yu, K Zhou, Y Bai, R Qi, S Zhang
J. Exp. Clin. Cancer Res., 2020-06-16;39(1):113.
Species: Human
Sample Types: Cell Culture Supernates
-
Intranasal delivery of icariin via a nanogel-thermoresponsive hydrogel compound system to improve its antidepressant-like activity
Authors: D Xu, YR Lu, N Kou, MJ Hu, QS Wang, YL Cui
Int J Pharm, 2020-06-15;586(0):119550.
Species: Rat
Sample Types: Plasma
-
Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma
Authors: Y Zhao, K He, H Zheng, M Sun, T Shi, X Zheng, D Shao, H Zhang, F Guan, J Li, L Chen
Onco Targets Ther, 2020-06-09;13(0):5223-5230.
Species: Human
Sample Types: Cell Culture Supernates
-
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo
Authors: Y Wu, Z Wang, Z Lin, X Fu, J Zhan, K Yu
Front Pharmacol, 2020-06-03;11(0):682.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture
Authors: S Di Blasio, GF van Wigche, A Becker, A van Duffel, M Gorris, K Verrijp, I Stefanini, GJ Bakker, M Bloemendal, A Halilovic, A Vasaturo, G Bakdash, SV Hato, JHW de Wilt, J Schalkwijk, IJM de Vries, JC Textor, EH van den Bo, M Tazzari, CG Figdor
Nat Commun, 2020-06-02;11(1):2749.
Species: Human
Sample Types: Cell Culture Supernates
-
TGF-beta1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In�Vivo
Authors: K Lynch, O Treacy, X Chen, N Murphy, P Lohan, MN Islam, E Donohoe, MD Griffin, L Watson, S McLoughlin, G O'Malley, AE Ryan, T Ritter
Mol. Ther., 2020-05-30;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cytokines Differently Define the Immunomodulation of Mesenchymal Stem Cells from the Periodontal Ligament
Authors: C Behm, A Blufstein, J Gahn, M Nemec, A Moritz, X Rausch-Fan, O Andrukhov
Cells, 2020-05-14;9(5):.
Species: Human
Sample Types: Conditioned Media
-
Anti-Inflammatory and Protein Tyrosine Phosphatase 1B Inhibitory Metabolites from the Antarctic Marine-Derived Fungal Strain Penicillium glabrum SF-7123
Authors: TM Ha, DC Kim, JH Sohn, JH Yim, H Oh
Mar Drugs, 2020-05-09;18(5):.
Species: Fungus
Sample Types: Fungal Extract
-
Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone
Authors: F Nishimura, H Mogami, K Moriuchi, Y Chigusa, M Mandai, E Kondoh
PLoS ONE, 2020-05-04;15(5):e0231944.
Species: Human
Sample Types: Cell Culture Supernates
-
Prostaglandin E2 receptor subtypes 1 and 2 play a role in TGF-beta1-induced renal fibrosis by regulating endoplasmic reticulum stress
Authors: NF Guo, Z Qiu, XL Chen, X Chen, JB Huang, J Liu
Eur Rev Med Pharmacol Sci, 2020-05-01;24(9):4954-4962.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Limited Proteolysis of Cyclooxygenase-2 Enhances Cell Proliferation
Authors: E Saadi, R Sood, I Dromi, R Srouji, OA Hatoum, S Tal, L Barki-Harr
Int J Mol Sci, 2020-04-30;21(9):.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of Balneotherapy in Jeju Magma-Seawater on Knee Osteoarthritis Model
Authors: CG Kim, DG Lee, J Oh, YH Lee, YJ Lee, PH Song, CH Song, SK Ku
Sci Rep, 2020-04-20;10(1):6620.
Species: Rat
Sample Types: Tissue Homogenates
-
Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis
Authors: M Lo Monaco, P Gervois, J Beaumont, P Clegg, A Bronckaers, JM Vandeweerd, I Lambrichts
Cells, 2020-04-15;9(4):.
Species: Mouse
Sample Types: Cell Culture Supernatants
-
TGF-&beta secreted by human umbilical cord blood-derived mesenchymal stem cells ameliorates atopic dermatitis by inhibiting secretion of TNF-&alpha and IgE
Authors: HH Park, S Lee, Y Yu, SM Yoo, SY Baek, N Jung, KW Seo, KS Kang
Stem Cells, 2020-04-14;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
In vitro Anti-Inflammatory and Anti-Oxidative Stress Activities of Kushenol C Isolated from the Roots of Sophoraflavescens
Authors: BO Cho, DN Che, JS Kim, JH Kim, JY Shin, HJ Kang, SI Jang
Molecules, 2020-04-12;25(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Machaerium hirtum (Vell.) Stellfeld Alleviates Acute Pain and Inflammation: Potential Mechanisms of Action
Authors: JA Lopes, VP Rodrigues, MMP Tangerina, LRMD Rocha, CM Nishijima, VVA Nunes, LFR Almeida, W Vilegas, ARSD Santos, M Sannomiya, CA Hiruma-Lim
Biomolecules, 2020-04-11;10(4):.
Species: Mouse
Sample Types: Tissue Homoegenates
-
Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization
Authors: L Yang, JY So, N Skrypek, HH Yang, AS Merchant, GW Nelson, WD Chen, H Ishii, JM Chen, G Hu, BR Achyut, EC Yoon, L Han, C Huang, MC Cam, K Zhao, MP Lee
Cancer Res., 2020-04-07;0(0):.
Species: Mouse
Sample Types: Tissue Homogenate
-
Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-kappaB Signal Transduction
Authors: KKA Sanjeewa, DP Nagahawatt, HW Yang, JY Oh, TU Jayawarden, YJ Jeon, M De Zoysa, I Whang, B Ryu
Biomolecules, 2020-03-27;10(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis
Authors: Y Zhao, J Wang, Z Min, L Peng, S Qi, W Lin
Mediators Inflamm., 2020-03-10;2020(0):6947482.
Species: Mouse
Sample Types: Aqueous Humor
-
Fucoxanthinol from the Diatom Nitzschia Laevis Ameliorates Neuroinflammatory Responses in Lipopolysaccharide-Stimulated BV-2 Microglia
Authors: Y Li, L Liu, P Sun, Y Zhang, T Wu, H Sun, KW Cheng, F Chen
Mar Drugs, 2020-02-17;18(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis
Authors: H Liu, X Xiong, W Zhai, T Zhu, X Zhu, Y Zhu, Y Peng, Y Zhang, J Wang, H Chen, Y Chen, A Guo
Microorganisms, 2020-01-31;8(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chondroprotective Effect of Cynaroside in IL-1&beta-Induced Primary Rat Chondrocytes and Organ Explants via NF-&kappaB and MAPK Signaling Inhibition
Authors: SA Lee, BR Park, SM Moon, JH Hong, DK Kim, CS Kim
Oxid Med Cell Longev, 2020-01-24;2020(0):9358080.
Species: Rat
Sample Types:
-
Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile
Authors: S Queckbörne, E Syk Lundbe, K Gemzell-Da, LC Davies
Stem Cell Res Ther, 2020-01-06;11(1):15.
Species: Human
Sample Types: Cell Culture Supernates
-
Knockdown of TRIM8 Attenuates IL-1beta-induced Inflammatory Response in Osteoarthritis Chondrocytes Through the Inactivation of NF-kappaB Pathway
Authors: R Liu, H Wu, H Song
Cell Transplant, 2020-01-01;29(0):9636897209436.
Species: Human
Sample Types: Cell Culture Supernates
-
Chondroprotective and anti-inflammatory effects of amurensin H by regulating TLR4/Syk/NF-kappaB signals
Authors: P Ma, L Yue, H Yang, Y Fan, J Bai, S Li, J Yuan, Z Zhang, C Yao, M Lin, Q Hou
J. Cell. Mol. Med., 2019-12-25;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
The Phenotype and Secretory Activity of Adipose-Derived Mesenchymal Stem Cells (ASCs) of Patients with Rheumatic Diseases
Authors: E Kuca-Warna, U Skalska, I Janicka, U Musia?owic, K Bonek, P G?uszko, P Szcz?sny, M Olesi?ska, E Kontny
Cells, 2019-12-17;8(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice
Authors: S Ni, Z Ling, X Wang, Y Cao, T Wu, R Deng, JL Crane, R Skolasky, S Demehri, G Zhen, A Jain, P Wu, D Pan, B Hu, X Lyu, Y Li, H Chen, H Qi, Y Guan, X Dong, M Wan, X Zou, H Lu, J Hu, X Cao
Nat Commun, 2019-12-10;10(1):5643.
Species: Mouse
Sample Types: Tissue Lysate
-
miR-644-5p carried by bone mesenchymal stem cell-derived exosomes targets regulation of p53 to inhibit ovarian granulosa cell apoptosis
Authors: B Sun, Y Ma, F Wang, L Hu, Y Sun
Stem Cell Res Ther, 2019-11-29;10(1):360.
Species: Mouse
Sample Types: Serum
-
Effect of carrageenans on some lipid metabolism components in vitro
Authors: EV Sokolova, AO Kravchenko, NV Sergeeva, VN Davydova, LN Bogdanovic, IM Yermak
Carbohydr Polym, 2019-11-16;230(0):115629.
Species: Human
Sample Types: Plasma
-
Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells
Authors: SY Kim, SH Oh, JH Lee, MW Suh, MK Park
Stem Cells Int, 2019-11-14;2019(0):4357684.
Species: Human
Sample Types: Cell Culture Supernates
-
Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-alpha-driven inflammation and ER stress
Authors: D Chen, D Lu, H Liu, E Xue, Y Zhang, P Shang, X Pan
EBioMedicine, 2019-11-14;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Nanosome-Mediated Delivery Of Protein Kinase D Inhibitor Protects Chondrocytes From Interleukin-1beta-Induced Stress And Apoptotic Death
Authors: H Cho, FU Bhatti, KA Hasty, AK Yi
Int J Nanomedicine, 2019-11-11;14(0):8835-8846.
Species: Porcine
Sample Types: Cell Culture Supernates
-
Protective effect of Platymiscium floribundum Vog. in tree extract on periodontitis inflammation in rats
Authors: JMO Freire, HV Chaves, AH Teixeira, LHT de Sousa, IR Pinto, JJDN Costa, NA de Sousa, KMA Pereira, VCC Girão, VCS Ferreira, JEÁ Dos Santos, MAS Lima, ATA Pimenta, RC Montenegro, MEA de Moraes, VPT Pinto, GC Filho, MM Bezerra
PLoS ONE, 2019-11-04;14(11):e0223800.
Species: Rat
Sample Types: Gingival Fluid
-
The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARgammaAgonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro
Authors: ? Uram, M Misiorek, M Pichla, A Filipowicz, J Markowicz, S Wo?owiec, E Wa?ajtys-R
Molecules, 2019-10-22;24(20):.
Species: Human
Sample Types: Cell Culture Supernates
-
The effectiveness of marine based fatty acid compound (PCSO-524) and firocoxib in the treatment of canine osteoarthritis
Authors: M Vijarnsorn, I Kwananocha, N Kashemsant, T Jarudecha, C Lekcharoen, B Beale, B Peirone, BDX Lascelles
BMC Vet. Res., 2019-10-17;15(1):349.
Species: Human
Sample Types: Serum
-
Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity
Authors: S Regmi, S Pathak, TP Thanh, TT Nguyen, JH Sung, S Yook, JO Kim, CS Yong, I Choi, KO Doh, PH Park, JB Park, Y Seo, BK Kim, DM Lee, IJ Moon, HS Kim, JH Jeong
Stem Cell Res Ther, 2019-10-16;10(1):230.
Species: Human
Sample Types: Cell Culture Supernates
-
(10Z)-Debromohymenialdisine from Marine Sponge Stylissa sp. Regulates Intestinal Inflammatory Responses in Co-Culture Model of Epithelial Caco-2 Cells and THP-1 Macrophage Cells
Authors: SM Lee, NH Kim, S Lee, YN Kim, JD Heo, JR Rho, EJ Jeong
Molecules, 2019-09-18;24(18):.
Species: Human
Sample Types: Cell Culture Supernates
-
A biological extract of turmeric (Curcuma longa) modulates response of cartilage explants to lipopolysaccharide
Authors: W Pearson, LS Kott
BMC Complement Altern Med, 2019-09-11;19(1):252.
Species: Porcine
Sample Types: Tissue Culture Supernates
-
Efficacy of 3D Culture Priming is Maintained in Human Mesenchymal Stem Cells after Extensive Expansion of the Cells
Authors: TJ Bartosh, JH Ylostalo
Cells, 2019-09-05;8(9):.
Species: Human
Sample Types: Spheroid
-
2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line
Authors: Y Shibaike, M Gotoh, C Ogawa, S Nakajima, K Yoshikawa, T Kobayashi, K Murakami-M
Biochem Biophys Rep, 2019-07-19;19(0):100668.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-inflammatory effects of the combined extracts of Achyranthes japonica nakai and Aralia continentalis kitagawa in�vitro and in�vivo
Authors: YM Woo, OJ Kim, ES Jo, SJ Kim, YH Lee, MY Ahn, SH Lee, JM Ha, A Kim
Data Brief, 2019-06-03;25(0):104088.
Species: Rat
Sample Types: Serum
-
The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming
Authors: Y Liu, H Ren, Y Zhou, L Shang, Y Zhang, F Yang, X Shi
J. Exp. Clin. Cancer Res., 2019-05-29;38(1):228.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation
Authors: CH Yu, B Suh, I Shin, EH Kim, D Kim, YJ Shin, SY Chang, SH Baek, H Kim, ON Bae
Int J Mol Sci, 2019-05-28;20(11):.
Species: Human, Mouse
Sample Types: Cell Culture Supernates
-
Intra-Articular Injection of 2 Different Dosages of Autologous and Allogeneic Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cells Triggers a Variable Inflammatory Response of the Fetlock Joint on 12 Sound Experimental Horses
Authors: L Bertoni, T Branly, S Jacquet, M Desancé, L Desquilbet, P Rivory, DJ Hartmann, JM Denoix, F Audigié, P Galéra, M Demoor
Stem Cells Int, 2019-05-02;2019(0):9431894.
Species: Equine
Sample Types: Synovial Fluid
-
Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane
Authors: DW Barrett, RK John, C Thrasivoul, A Mata, JA Deprest, DL Becker, AL David, TT Chowdhury
Sci Rep, 2019-04-30;9(1):6718.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay -
Assembly of Human Stem Cell-Derived Cortical Spheroids and Vascular Spheroids to Model 3-D Brain-like Tissues
Authors: L Song, X Yuan, Z Jones, K Griffin, Y Zhou, T Ma, Y Li
Sci Rep, 2019-04-12;9(1):5977.
Species: Human
Sample Types: Cell Culture Supernates
-
6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity
Authors: YG Lee, H Lee, JA Ryuk, JT Hwang, HG Kim, DS Lee, YJ Kim, DC Yang, BS Ko, NI Baek
Bioorg. Chem., 2019-04-11;88(0):102922.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chemical constituents from Vietnamese mangrove Calophyllum inophyllum and their anti-inflammatory effects
Authors: N Van Thanh, HJ Jang, LB Vinh, KTP Linh, PTT Huong, NX Cuong, NH Nam, C Van Minh, YH Kim, SY Yang
Bioorg. Chem., 2019-04-11;88(0):102921.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Suppression of inflammatory mediators and matrix metalloproteinase (MMP)-13 by Morus alba stem extract and oxyresveratrol in RAW 264.7?cells and C28/I2 human chondrocytes
Authors: T Wongwat, K Srihaphon, C Pitaksuthe, W Boonyo, T Pitaksutee
J Tradit Complement Med, 2019-03-22;10(2):132-140.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Rosmarinic Acid Enriched Fraction from Perilla frutescens Leaves Strongly Protects Indomethacin-Induced Gastric Ulcer in Rats
Authors: N Kangwan, K Pintha, S Lekawanvij, M Suttajit
Biomed Res Int, 2019-03-04;2019(0):9514703.
Species: Rat
Sample Types: Serum
-
Chemical Constituents and an Antineuroinflammatory Lignan, Savinin from the Roots of Acanthopanax henryi
Authors: XJ Li, KW Kim, H Oh, XQ Liu, YC Kim
Evid Based Complement Alternat Med, 2019-02-21;2019(0):1856294.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells
Authors: A Islam, I Urbarova, JA Bruun, I Martinez-Z
Eur Cell Mater, 2019-02-20;37(0):153-174.
Species: Human
Sample Types: Cell Culture Supernates
-
Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems
Authors: V Miceli, M Pampalone, S Vella, AP Carreca, G Amico, PG Conaldi
Stem Cells Int, 2019-02-18;2019(0):7486279.
Species: Human
Sample Types: Cell Culture Supernates
-
Stem cells from human exfoliated deciduous teeth correct the immune imbalance of allergic rhinitis via Treg cells in vivo and in vitro
Authors: YY Dai, SY Ni, K Ma, YS Ma, ZS Wang, XL Zhao
Stem Cell Res Ther, 2019-01-22;10(1):39.
Species: Human
Sample Types: Cell Culture Supernates
-
CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis
Authors: XY Jia, Y Chang, F Wei, X Dai, YJ Wu, XJ Sun, S Xu, HX Wu, C Wang, XZ Yang, W Wei
Acta Pharmacol. Sin., 2019-01-14;0(0):.
Species: Rat
Sample Types: Serum
-
Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen
Authors: D Zhu, C Chen, L Bai, L Kong, J Luo
Evid Based Complement Alternat Med, 2019-01-13;2019(0):9406342.
Species: Human, Rat
Sample Types: Cell Culture Supernates, Tissue Homogenates
-
Anti-Arthritis Effect through the Anti-Inflammatory Effect of Sargassum muticum Extract in Collagen-Induced Arthritic (CIA) Mice
Authors: H Jeon, WJ Yoon, YM Ham, SA Yoon, SC Kang
Molecules, 2019-01-13;24(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The protective effect of sinapic acid in osteoarthritis: In vitro and in vivo studies
Authors: X Li, J Lin, X Ding, J Xuan, Z Hu, D Wu, X Zhu, Z Feng, W Ni, A Wu
J. Cell. Mol. Med., 2019-01-03;0(0):.
Species: Human
Sample Types: Tissue Homogenates
-
Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats
Authors: X Zhao, J Li, Y Meng, M Cao, J Wang
Evid Based Complement Alternat Med, 2019-01-03;2019(0):7365841.
Species: Rat
Sample Types: Tissue Homogenates
-
GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation
Authors: L Jiang, Q Jiang, S Yang, S Huang, X Han, J Duan, S Pan, M Zhao, S Guo
Pulm Pharmacol Ther, 2018-12-31;0(0):.
Species: Mouse
Sample Types: BALF
-
Anti-neuroinflammatory effects of cudraflavanone A isolated from the chloroform fraction of Cudrania tricuspidata root bark
Authors: KW Kim, TH Quang, W Ko, DC Kim, CS Yoon, H Oh, YC Kim
Pharm Biol, 2018-12-01;56(1):192-200.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of skin carcinogenesis by suppression of NF-?B dependent ITGAV and TIMP-1 expression in IL-32? overexpressed condition
Authors: YS Lee, CH Lee, JT Bae, KT Nam, DB Moon, OK Hwang, JS Choi, TH Kim, HO Jun, YS Jung, DY Hwang, SB Han, DY Yoon, JT Hong
J. Exp. Clin. Cancer Res., 2018-11-28;37(1):293.
Species: Mouse
Sample Types: Serum
-
Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-?B Pathway
Authors: J Hou, Y Gu, S Zhao, M Huo, S Wang, Y Zhang, Y Qiao, X Li
Molecules, 2018-11-27;23(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective Effects of Morus Root Extract (MRE) Against Lipopolysaccharide-Activated RAW264.7 Cells and CCl4-Induced Mouse Hepatic Damage
Authors: TH Tseng, WL Lin, CK Chang, KC Lee, SY Tung, HC Kuo
Cell. Physiol. Biochem., 2018-11-27;51(3):1376-1388.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory and Neuroprotective Effects of Fungal Immunomodulatory Protein Involving Microglial Inhibition
Authors: WY Chen, CY Chang, JR Li, JD Wang, CC Wu, YH Kuan, SL Liao, WY Wang, CJ Chen
Int J Mol Sci, 2018-11-21;19(11):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: Histomorphometrical, Immunohistochemical, Imunological and Microbiological Analyses
Authors: M Longo, V Gouveia Ga, E Ervolino, ML Ferro Alve, C Duque, M Wainwright, LH Theodoro
Photodiagnosis Photodyn Ther, 2018-11-20;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
-
HO-1 Induction by Selaginella tamariscina Extract Inhibits Inflammatory Response in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages
Authors: AN Won, SA Kim, JY Ahn, JH Han, CH Kim, JH Lee, DI Kim
Evid Based Complement Alternat Med, 2018-11-18;2018(0):7816923.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dietary ?-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD
Authors: S Rutting, M Papanicola, D Xenaki, LG Wood, AM Mullin, PM Hansbro, BG Oliver
Respir. Res., 2018-11-03;19(1):211.
Species: Human
Sample Types: Cell Culture Supernates
-
Human Wharton's jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors
Authors: JE Millán-Riv, FM Nadal-Nico, D García-Ber, P Sobrado-Ca, M Blanquer, JM Moraleda, M Vidal-Sanz, M Agudo-Barr
Sci Rep, 2018-11-02;8(1):16299.
Species: Human
Sample Types: Cell Culture Supernates
-
Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats
Authors: CT Hsieh, YJ Lee, X Dai, NB Ojeda, HJ Lee, LT Tien, LW Fan
Int J Mol Sci, 2018-09-27;19(10):.
Species: Rat
Sample Types: Tissue Homogenates
-
1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade
Authors: W Dankers, C González-L, N Davelaar, PS Asmawidjaj, AMC Mus, JMW Hazes, EM Colin, E Lubberts
Arthritis Res. Ther., 2018-09-20;20(1):212.
Species: Human
Sample Types: Cell Culture Supernates
-
Isolation of Novel Sesquiterpeniods and Anti-neuroinflammatory Metabolites from Nardostachys jatamansi
Authors: CS Yoon, DC Kim, JS Park, KW Kim, YC Kim, H Oh
Molecules, 2018-09-17;23(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
Authors: LC Dutton, J Dudhia, B Catchpole, H Hodgkiss-G, D Werling, DJ Connolly
Sci Rep, 2018-09-06;8(1):13351.
Species: Canine
Sample Types: Cell Culture Supernates
-
Lepidiumuridine A: A New Natural Uridine Derivative as a Phytoestrogen Isolated from the Seeds of Lepidium apetalum Willd
Authors: M Li, M Zeng, ZG Zhang, B Zhang, J Zhang, X Zheng, W Feng
Evid Based Complement Alternat Med, 2018-09-04;2018(0):2813465.
Species: Mouse
Sample Types: Serum
-
Changes in erythrocyte polyunsaturated fatty acids and plasma eicosanoids level in patients with asthma
Authors: J Zhou, L Chen, Z Liu, L Sang, Y Li, D Yuan
Lipids Health Dis, 2018-09-01;17(1):206.
Species: Human
Sample Types: Plasma
-
IL-33 facilitates proliferation of colorectal cancer dependent on�COX2/PGE2
Authors: Y Li, J Shi, S Qi, J Zhang, D Peng, Z Chen, G Wang, Z Wang, L Wang
J. Exp. Clin. Cancer Res., 2018-08-17;37(1):196.
Species: Human
Sample Types: Cell Culture Supernates
-
The Protective Effect of Ligustilide in Osteoarthritis: An in Vitro and in Vivo Study
Authors: X Li, D Wu, Z Hu, J Xuan, X Ding, G Zheng, Z Feng, W Ni, A Wu
Cell. Physiol. Biochem., 2018-08-17;48(6):2583-2595.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory Effect of a Polyphenol-Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages and Acetaminophen-Induced Liver Injury in Mice
Authors: H Wu, H Pang, Y Chen, L Huang, H Liu, Y Zheng, C Sun, G Zhang, G Wang
Oxid Med Cell Longev, 2018-08-07;2018(0):7858094.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effects of Surface Nanotopography and Calcium Chemistry of Titanium Bone Implants on Early Blood Platelet and Macrophage Cell Function
Authors: JW Park, SH Han, T Hanawa
Biomed Res Int, 2018-07-04;2018(0):1362958.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL.Faslpr Mice
Authors: HK Lee, KH Kim, HS Kim, JS Kim, JH Lee, A Ji, KS Kim, TY Lee, IY Chang, SC Bae, JT Hong, Y Kim, SB Han
Stem Cells Int, 2018-07-03;2018(0):4273107.
Species: Human
Sample Types: Cell Culture Supernates
-
Adenine attenuates lipopolysaccharide-induced inflammatory reactions
Authors: P Silwal, K Lim, JY Heo, JI Park, U Namgung, SK Park
Korean J. Physiol. Pharmacol., 2018-06-25;22(4):379-389.
Species: Mouse
Sample Types: Cell Culture Supernates
-
AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment
Authors: R Kalra, E Bhagyaraj, D Tiwari, R Nanduri, AP Chacko, M Jain, S Mahajan, N Khatri, P Gupta
Oncogenesis, 2018-05-25;7(5):43.
Species: Human
Sample Types: Cell Culture Supernates
-
Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss
Authors: Y Zhou, G Wang, D Li, Y Wang, Q Wu, J Shi, F Zhang
J Neuroinflammation, 2018-05-25;15(1):161.
Species: Rat
Sample Types: Cell Culture Supernates
-
Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction
Authors: M Li, D Khong, LY Chin, A Singleton, B Parekkadan
Sci Rep, 2018-05-01;8(1):6816.
Species: Human
Sample Types: Cell Culture Supernates
-
Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms
Authors: JA Ocana, E Romer, R Sahu, SC Pawelzik, GA FitzGerald, MH Kaplan, JB Travers
J. Immunol., 2018-04-25;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Donor-dependent variation of human umbilical cord blood mesenchymal stem cells in response to hypoxic preconditioning and amelioration of limb ischemia
Authors: I Kang, BC Lee, SW Choi, JY Lee, JJ Kim, BE Kim, DH Kim, SE Lee, N Shin, Y Seo, HS Kim, DI Kim, KS Kang
Exp. Mol. Med., 2018-04-20;50(4):35.
Species: Human
Sample Types: Cell Culture Supernates
-
Three macrophage subsets are identified in the uterus during early human pregnancy
Authors: X Jiang, MR Du, M Li, H Wang
Cell. Mol. Immunol., 2018-04-04;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity
Authors: MH Lee, AR Han, M Jang, HK Choi, SY Lee, KT Kim, TG Lim
Oxid Med Cell Longev, 2018-04-03;2018(0):5967150.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adipose-derived stem cells ameliorate colitis by suppression of inflammasome formation and regulation of M1-macrophage population through prostaglandin E2
Authors: HJ Park, J Kim, FT Saima, KJ Rhee, S Hwang, MY Kim, SK Baik, YW Eom, HS Kim
Biochem. Biophys. Res. Commun., 2018-03-16;0(0):.
Species: Human
Sample Types: THP-1 cells
-
Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models
Authors: MM Rahman, HK Kim, SE Kim, MJ Kim, DH Kim, HS Lee
Nutrients, 2018-03-15;10(3):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Evaluation of conjugated linoleic acid (CLA) supplementation on markers of joint inflammation and cartilage metabolism in young horses challenged with lipopolysaccharide
Authors: AN Bradbery, JA Coverdale, KL Vernon, JL Leatherwoo, CE Arnold, RA Dabareiner, MK Kahn, AA Millican, TH Welsh
J. Anim. Sci., 2018-03-06;0(0):.
Species: Equine
Sample Types: Synovial Fluid
-
PGE2-EP3 signaling exacerbates hippocampus-dependent cognitive impairment after laparotomy by reducing expression levels of hippocampal synaptic plasticity-related proteins in aged mice
Authors: JY Xiao, BR Xiong, W Zhang, WC Zhou, H Yang, F Gao, HB Xiang, A Manyande, XB Tian, YK Tian
CNS Neurosci Ther, 2018-02-27;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury
Authors: SJ Kim, WK Ko, MJ Jo, Y Arai, H Choi, H Kumar, IB Han, S Sohn
Sci Rep, 2018-02-16;8(1):3176.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Arsenic Promotes the COX2/PGE2-SOX2 Axis to Increase the Malignant Stemness Properties of Urothelial Cells
Authors: A Ooki, A Begum, L Marchionni, CJ VandenBuss, S Mao, K Max, MO Hoque
Int. J. Cancer, 2018-02-14;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Cryptotanshinone inhibits prostaglandin E2 production and COX-2 expression via suppression of TLR4/NF-?B signaling pathway in LPS-stimulated Caco-2 cells
Authors: SG Cao, H Wang, LM Lin, XP Xia, H Wu
Microb. Pathog., 2018-01-17;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways
Authors: L Subedi, OW Kwon, C Pak, G Lee, K Lee, H Kim, SY Kim
BMC Neurosci, 2017-12-28;18(1):82.
Species: Human
Sample Types: Cell Culture Supernates
-
Identification of haptoglobin switch-on status in archived placental specimens indicates antenatal exposure to inflammation and potential participation of the fetus in triggering preterm birth
Authors: ME McCarthy, CS Buhimschi, JT Hardy, AT Dulay, CA Laky, MO Bahtyiar, R Papanna, G Zhao, IA Buhimschi
Placenta, 2017-12-24;62(0):50-57.
Species: Human
Sample Types: Tissue Culture Supernates
-
Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced Septic Mice
Authors: YK Kim, MG Yeo, BK Oh, HY Kim, HJ Yang, SS Cho, M Gil, KJ Lee
Int J Mol Sci, 2017-12-18;18(12):.
Species: Mouse
Sample Types: Serum
-
Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway
Authors: L Cui, Y Zhao, Y Pan, X Zheng, D Shao, Y Jia, K He, K Li, L Chen
Onco Targets Ther, 2017-12-08;10(0):5817-5826.
Species: Human
Sample Types: Cell Culture Supernates
-
Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis
Authors: T Lin, J Pajarinen, A Nabeshima, L Lu, K Nathan, E Jämsen, Z Yao, SB Goodman
Stem Cell Res Ther, 2017-12-06;8(1):277.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory coumarins from Paramignya trimera
Authors: HL Tuan Anh, DC Kim, W Ko, TM Ha, NX Nhiem, PH Yen, BH Tai, LH Truong, VN Long, T Gioi, T Hong Quang, CV Minh, H Oh, YC Kim, PV Kiem
Pharm Biol, 2017-12-01;55(1):1195-1201.
Species: Mouse
Sample Types: Cell Culture Supernates
-
YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells
Authors: A Ooki, M Del Carmen, L Marchionni, W Dinalankar, A Begum, NM Hahn, CJ VandenBuss, ZA Rasheed, S Mao, GJ Netto, D Sidransky, MO Hoque
Cancer Res., 2017-11-27;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Asperflavin, an Anti-Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami
Authors: X Yang, MC Kang, Y Li, EA Kim, SM Kang, YJ Jeon
Molecules, 2017-10-29;22(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Saikosaponin A inhibits IL-1?-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXR?
Authors: H Gao, Y Song, D Li, W Feng, J Liu
Oncotarget, 2017-09-30;8(51):88941-88950.
Species: Human
Sample Types: Cell Culture Supernates
-
Therapeutic effects of lornoxicam-loaded nanomicellar formula in experimental models of rheumatoid arthritis
Authors: HS Helmy, AE El-Sahar, RH Sayed, RN Shamma, AH Salama, EM Elbaz
Int J Nanomedicine, 2017-09-22;12(0):7015-7023.
Species: Rat
Sample Types: Serum
-
Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets
Authors: S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi
Cell Rep, 2017-09-19;20(12):2891-2905.
Species: Human
Sample Types: Cell Culture Supernates
-
Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages
Authors: JN Kim, SN Han, TJ Ha, HK Kim
Nutr Res Pract, 2017-09-18;11(5):357-364.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective effect of decursin and decursinol angelate-rich Angelica gigas Nakai extract on dextran sulfate sodium-induced murine ulcerative colitis
Authors: SR Oh, S Ok, TS Jung, SO Jeon, JM Park, JW Jung, DS Ryu
Asian Pac J Trop Med, 2017-09-13;10(9):864-870.
Species: Mouse
Sample Types: Tissue Homogenates
-
Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo
Authors: W Zheng, Z Feng, Y Lou, C Chen, C Zhang, Z Tao, H Li, L Cheng, X Ying
Oncotarget, 2017-08-24;8(59):99649-99665.
Species: Human
Sample Types: Cell Culture Supernates
-
Suppressive Effect of the n-Hexane Extract of Litsea japonica Fruit Flesh on Monosodium-Iodoacetate-Induced Osteoarthritis in Rats
Authors: SH Kim, HJ Choi, WK Yang, JE Lee, JH Cho, IJ Park, S Park, BK Park, M Jin
Evid Based Complement Alternat Med, 2017-08-22;2017(0):1791403.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Kaempferol Alleviates the Interleukin-1?-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-?B
Authors: Z Zhuang, G Ye, B Huang
Med. Sci. Monit., 2017-08-14;23(0):3925-3931.
Species: Rat
Sample Types: Cell Culture Supernates
-
Resolvin D1 Improves the Resolution of Inflammation via Activating NF-?B p50/p50-Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome
Authors: Y Gao, H Zhang, L Luo, J Lin, D Li, S Zheng, H Huang, S Yan, J Yang, Y Hao, H Li, F Gao Smith, S Jin
J. Immunol., 2017-08-09;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
-
3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis
Authors: J Jeon, LJ Kang, KM Lee, C Cho, EK Song, W Kim, TJ Park, S Yang
J. Cell. Mol. Med., 2017-08-07;0(0):.
Species: Mouse
Sample Types: Cell Lysates
-
IL-33 Signaling Regulates Innate IL-17A and IL-22 Production via Suppression of Prostaglandin E2 during Lung Fungal Infection
Authors: JM Garth, KM Reeder, MS Godwin, JJ Mackel, CW Dunaway, JP Blackburn, C Steele
J. Immunol., 2017-08-07;199(6):2140-2148.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats
Authors: JW Jeong, HH Lee, J Kim, EO Choi, H Hwang-Bo, HJ Kim, MY Kim, KI Ahn, GY Kim, KW Lee, KY Kim, SG Kim, SH Hong, C Park, HJ Cha, YH Choi
Mol Med Rep, 2017-07-21;0(0):.
Species: Rat
Sample Types: Serum
-
Cynanchum wilfordii Polysaccharides Suppress Dextran Sulfate Sodium-Induced Acute Colitis in Mice and the Production of Inflammatory Mediators from Macrophages
Authors: CW Cho, S Ahn, TG Lim, HD Hong, YK Rhee, DC Yang, M Jang
Mediators Inflamm., 2017-06-20;2017(0):3859856.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells
Authors: SA Engen, GH Rørvik, O Schreurs, IJ Blix, K Schenck
Int J Oral Sci, 2017-06-16;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Cigarette Smoke Regulates Calcium-Independent Phospholipase A2 Metabolic Pathways in Breast Cancer
Authors: S Kispert, T Schwartz, J McHowat
Am. J. Pathol., 2017-06-12;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Early Gut Microbiota Intervention Suppresses DSS-Induced Inflammatory Responses by Deactivating TLR/NLR Signalling in Pigs
Authors: Y Xiao, H Yan, H Diao, B Yu, J He, J Yu, P Zheng, X Mao, Y Luo, D Chen
Sci Rep, 2017-06-12;7(1):3224.
Species: Porcine
Sample Types: Tissue Culture Supernates
-
Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength
Authors: ATV Ho, AR Palla, MR Blake, ND Yucel, YX Wang, KEG Magnusson, CA Holbrook, PE Kraft, SL Delp, HM Blau
Proc. Natl. Acad. Sci. U.S.A., 2017-06-12;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bovine embryo induces an anti-inflammatory response in uterine epithelial cells and immune cells in vitro: possible involvement of interferon tau as an intermediator
Authors: AK Talukder, MS Yousef, MB Rashid, K Awai, TJ Acosta, T Shimizu, K Okuda, M Shimada, K Imakawa, A Miyamoto
J. Reprod. Dev., 2017-06-10;0(0):.
Species: Bovine
Sample Types: Cell Culture Supernates
-
Aronia melanocarpa (Black Chokeberry) Reduces Ethanol-Induced Gastric Damage via Regulation of HSP-70, NF-?B, and MCP-1 Signaling
Authors: A Paulrayer, A Adithan, JH Lee, KH Moon, DG Kim, SY Im, CW Kang, NS Kim, JH Kim
Int J Mol Sci, 2017-06-05;18(6):.
Species: Rat
Sample Types: Tissue Homogenates
-
Francisella novicida inhibits spontaneous apoptosis and extends human neutrophil lifespan
Authors: LC Kinkead, DC Fayram, LH Allen
J. Leukoc. Biol., 2017-05-26;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Glycyrrhizin inhibits LPS-induced inflammatory mediator production in endometrial epithelial cells
Authors: XR Wang, HG Hao, L Chu
Microb. Pathog., 2017-05-25;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oxysophocarpine reduces oxygen-glucose deprivation-induced microglial activation and injury
Authors: Y Lu, J Lou, X Liu, S Wang
Am J Transl Res, 2017-05-15;9(5):2266-2275.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibitory effects on the production of inflammatory mediators and reactive oxygen species by Mori folium in lipopolysaccharide-stimulated macrophages and zebrafish
Authors: DH Kwon, JW Jeong, EO Choi, HW Lee, KW Lee, KY Kim, SG Kim, SH Hong, GY Kim, C Park, HJ Hwang, CG Son, YH Choi
An. Acad. Bras. Cienc., 2017-05-01;89(1):661-674.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory effects of novel polygonum multiflorum compound via inhibiting NF-?B/MAPK and upregulating the Nrf2 pathways in LPS-stimulated microglia
Authors: SY Park, ML Jin, NJ Kang, G Park, YW Choi
Neurosci. Lett., 2017-04-27;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adipose-derived mesenchymal stem cells modulate CD14(++)CD16(+) expression on monocytes from sepsis patients in vitro via prostaglandin E2
Authors: G Qiu, G Zheng, M Ge, L Huang, H Tong, P Chen, D Lai, Y Hu, B Cheng, Q Shu, J Xu
Stem Cell Res Ther, 2017-04-26;8(1):97.
Species: Human
Sample Types: Cell Culture Supernates
-
Berbamine Exerts Anti-Inflammatory Effects via Inhibition of NF-?B and MAPK Signaling Pathways
Authors: XJ Jia, X Li, F Wang, HQ Liu, DJ Zhang, Y Chen
Cell. Physiol. Biochem., 2017-04-26;41(6):2307-2318.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective effect of Shenmai injection on knee articular cartilage of osteoarthritic rabbits and IL-1?-stimulated human chondrocytes
Authors: N Yao, N Chen, X Xu, D Sun, W Liu, G Li, X Bi, S Li, Z Chen, G Chen, H Gan
Exp Ther Med, 2017-04-18;13(6):3013-3020.
Species: Human
Sample Types: Cell Culture Supernates
-
CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation-resistant tissues
Authors: Farshid Guilak
Arthritis & rheumatology, 2017-03-31;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Leaves of Raphanus sativus L. Shows Anti-Inflammatory Activity in LPS-Stimulated Macrophages via Suppression of COX-2 and iNOS Expression
Authors: HJ Park, M Song
Prev Nutr Food Sci, 2017-03-31;22(1):50-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toward understanding the role of cartilage particulates in synovial inflammation
Authors: AM Silverstei, RM Stefani, E Sobczak, EL Tong, MG Attur, RP Shah, JC Bulinski, GA Ateshian, CT Hung
Osteoarthr. Cartil., 2017-03-30;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Pro-inflammatory M1 macrophages promote osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway
Authors: LY Lu, F Loi, K Nathan, TH Lin, J Pajarinen, E Gibon, A Nabeshima, L Cordova, E Jämsen, Z Yao, SB Goodman
J. Orthop. Res, 2017-03-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform
Authors: I Rudnik-Jan, S Colen, J Berard, S Plomp, I Que, M van Rijen, N Woike, A Egas, G van Osch, E van Maarse, K Messier, A Chan, J Thies, L Creemers
J Control Release, 2017-03-09;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Combination therapy with butyrate and docosahexaenoic acid for keloid fibrogenesis: an in vitro study
Authors: K Torii, N Maeshige, M Aoyama-Ish, M Miyoshi, H Terashi, M Usami
An Bras Dermatol, 2017-03-01;92(2):184-190.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-33 promotes colon cancer cell stemness via JNK activation and macrophage recruitment
Authors: M Fang, Y Li, K Huang, S Qi, J Zhang, W Zgodzinski, M Majewski, G Wallner, S Gozdz, P Macek, A Kowalik, M Pasiarski, E Grywalska, L Vatan, N Nagarsheth, W Li, L Zhao, I Kryczek, G Wang, Z Wang, W Zou, L Wang
Cancer Res, 2017-03-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro
Authors: L Subedi, E Ji, D Shin, J Jin, JH Yeo, SY Kim
Nutrients, 2017-02-27;9(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Stellera chamaejasme and its constituents induce cutaneous wound healing and anti-inflammatory activities
Authors: M Kim, HJ Lee, A Randy, JH Yun, SR Oh, CW Nho
Sci Rep, 2017-02-21;7(0):42490.
Species: Human
Sample Types: Cell Culture Supernates
-
Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria
Authors: J Lee, YH Nho, SK Yun, YS Hwang
BMC Complement Altern Med, 2017-02-16;17(1):113.
Species: Human, Mouse
Sample Types: Cell Culture Supernates
-
Pro-inflammatory Signaling in a 3D Organotypic Skin Model after Low LET Irradiation-NF-?B, COX-2 Activation, and Impact on Cell Differentiation
Authors: A Acheva, G Schettino, KM Prise
Front Immunol, 2017-02-10;8(0):82.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation
Authors: A Sapkota, BP Gaire, KS Cho, SJ Jeon, OW Kwon, DS Jang, SY Kim, JH Ryu, JW Choi
PLoS ONE, 2017-02-08;12(2):e0171479.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Evaluation of an Aqueous Extract from Horseradish Root (Armoracia rusticana Radix) against Lipopolysaccharide-Induced Cellular Inflammation Reaction
Authors: C Herz, HT Tran, MR Márton, R Maul, S Baldermann, M Schreiner, E Lamy
Evid Based Complement Alternat Med, 2017-01-15;2017(0):1950692.
Species: Human
Sample Types: Cell Culture Supernates
-
Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-?B activation and MAPK phosphorylation
Authors: SY Kim, SM Park, M Hwangbo, JR Lee, SH Byun, SK Ku, IJ Cho, SC Kim, SY Jee, SJ Park
BMC Complement Altern Med, 2017-01-13;17(1):46.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
Autophagy, 2017-01-01;0(0):0.
Species: Mouse
Sample Types: Tissue Homogenates
-
The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial
Authors: DJ Allison, DA Gabriel, P Klentrou, AR Josse, DS Ditor
Top Spinal Cord Inj Rehabil, 2017-01-01;23(4):377-385.
Species: Human
Sample Types: Serum
-
Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots
Molecules, 2016-12-26;22(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chondrocyte-derived extracellular matrix suppresses pathogenesis of human pterygium epithelial cells by blocking the NF-?B signaling pathways
Authors: H Lee, M Lee, Y Lee, S Choi, J Yang
Mol. Vis, 2016-12-24;22(0):1490-1502.
Species: Human
Sample Types: Cell Culture Supernates
-
The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection
PLoS ONE, 2016-12-15;11(12):e0168102.
Species: Human
Sample Types: Cell Culture Supernates
-
Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo
Authors: Jisang Park
Int. Immunopharmacol, 2016-12-14;43(0):91-98.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
Sci Rep, 2016-12-02;6(0):38308.
Species: Human
Sample Types: Cell Culture Supernates
-
Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression
Authors: Jun Lu
Brain Res. Bull, 2016-11-30;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
-
MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis
Proc. Natl. Acad. Sci. U.S.A., 2016-11-21;113(49):E7917-E7926.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia
Authors: Li Chang-Qing
Int. Immunopharmacol., 2016-11-19;42(0):44-48.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Matrix Metalloproteinase Activity and Prostaglandin E2 are Elevated in the Synovial Fluid of Meniscus Tear Patients
Authors: Amy L McNulty
Connect. Tissue Res., 2016-11-04;0(0):.
Species: Human
Sample Types: Synovial Fluid
-
Indoleamine 2,3-Dioxygenase Is Not a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation through Adipose-Derived Stem Cells
PLoS ONE, 2016-11-03;11(11):e0165661.
Species: Mouse
Sample Types: Serum
-
Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush
Invest. Ophthalmol. Vis. Sci., 2016-11-01;57(14):6098-6106.
Species: Rat
Sample Types: Tissue Homogenates
-
Prostaglandin E2, trace elements and levels of oxidative processes in spontaneous miscarriages
Eur Rev Med Pharmacol Sci, 2016-11-01;20(22):4786-4790.
Species: Human
Sample Types: Plasma
-
Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1?-Induced Inflammation and Apoptosis in Chondrocytes
Biomed Res Int, 2016-10-30;2016(0):6290957.
Species: Rat
Sample Types: Cell Culture Supernates
-
Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.
Authors: Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg
PloS Pathogens, 2016-10-12;0(0):1553-7374.
Species: Human
Sample Types: Cell Culture Supernates
-
The role of extracellular vesicle and tunneling nanotube-mediated intercellular cross-talk between mesenchymal stem cells and human peripheral T cells
Stem Cells Dev, 2016-10-04;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-?B Activation
Authors: Yoonsook Kim
Pharmacogn Mag, 2016-10-01;12(48):295-301.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory effect of tricin isolated from Alopecurus aequalis Sobol. on the LPS-induced inflammatory response in RAW 264.7 cells
Authors: Byoung-Man Kang
Int. J. Mol. Med, 2016-09-30;38(5):1614-1620.
Species: Mouse
Sample Types: Cell Culture Supernates
-
24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats
PLoS ONE, 2016-08-30;11(8):e0161782.
Species: Rat
Sample Types: Cell Culture Supernates
-
Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells
Int J Mol Sci, 2016-08-19;17(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages
Authors: S Danesh Mes, J Sharbati, R Einspanier, C Gabler
Reprod. Biol. Endocrinol, 2016-08-15;14(1):44.
Species: Bovine
Sample Types: Cell Culture Supernates
-
Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation
Sci Rep, 2016-07-26;6(0):30263.
Species: Human
Sample Types: Cell Culture Supernates
-
Endothelial Cell Response to Fusobacterium nucleatum.
Authors: Mendes R, Pamuk F
Infect Immun, 2016-06-23;84(7):2141-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory Effects of Agrimoniin-Enriched Fractions of Potentilla erecta
Authors: Julia Hoffmann
Molecules, 2016-06-18;21(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
Authors: Chan-Mi Lee
Cell Biosci, 2016-06-16;6(0):43.
Species: Human
Sample Types: Cell Culture Supernates
-
Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation
Authors: S Arancibia, A Barrientos, J Torrejón, A Escobar, CJ Beltrán
Nanomedicine (Lond), 2016-04-15;0(0):.
Species: Mouse
Sample Types: Cell Lysates
-
Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines
Authors: DC Kim, KH Cho, W Ko, CS Yoon, JH Sohn, JH Yim, YC Kim, H Oh
Int J Mol Sci, 2016-04-08;17(4):.
Species: Mouse
Sample Types: Cell Lysates
-
Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
J Leukoc Biol, 2016-04-05;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Human Liver Stem Cells Suppress T-Cell Proliferation, NK Activity, and Dendritic Cell Differentiation
Authors: S Bruno, C Grange, M Tapparo, C Pasquino, R Romagnoli, E Dametto, A Amoroso, C Tetta, G Camussi
Stem Cells Int, 2016-04-04;2016(0):8468549.
Species: Human
Sample Types: Cell Culture Supernates
-
Canine and Equine Mesenchymal Stem Cells Grown in Serum Free Media Have Altered Immunophenotype.
Authors: Clark K, Kol A, Shahbenderian S, Granick J, Walker N, Borjesson D
Stem Cell Rev, 2016-04-01;12(2):245-56.
Species: Canine
Sample Types: Cell Culture Supernates
-
NF-?B Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors
Authors: Gwendolyn Sowa
Phys Ther, 2016-02-18;96(5):704-11.
Species: Rabbit
Sample Types: Cell Culture Supernates
-
Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.
Authors: Lee S, Yi J, Bae W, Lee S, Cha H, Kim E
PLoS ONE, 2016-01-20;11(1):e0146708.
Species: Human
Sample Types: Cell Culture Supernates
-
Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome.
Authors: Marentette J, Hurst R, McHowat J
PLoS ONE, 2015-06-09;10(6):e0129466.
Species: Human
Sample Types: Cell Culture Supernates
-
Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators.
Authors: Hinden L, Shainer R, Almogi-Hazan O, Or R
Stem Cells, 2015-05-13;33(7):2256-67.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment.
Authors: Li P, Shan J, Chen X, Zhang D, Su L, Huang X, Yu B, Zhi Q, Li C, Wang Y, Tomei S, Cai Q, Ji J, Li J, Chouchane L, Yu Y, Sun F, Xu Z, Liu B, Zhu Z
Cell Res, 2015-04-28;25(5):588-603.
Species: Human
Sample Types: Cell Culture Supernates
-
Crotoxin from Crotalus durissus terrificus is able to down-modulate the acute intestinal inflammation in mice.
Authors: Almeida C, Andrade-Oliveira V, Camara N, Jacysyn J, Faquim-Mauro E
PLoS ONE, 2015-04-08;10(4):e0121427.
Species: Mouse
Sample Types: Tissue Homogenates
-
Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions.
Authors: Arab H, Salama S, Omar H, Arafa E, Maghrabi I
PLoS ONE, 2015-03-30;10(3):e0122417.
Species: Rat
Sample Types: Tissue Homogenates
-
Mesenchymal stem cells alleviate airway inflammation and emphysema in COPD through down-regulation of cyclooxygenase-2 via p38 and ERK MAPK pathways.
Authors: Gu, Wen, Song, Lin, Li, Xiao-Min, Wang, Di, Guo, Xue-Jun, Xu, Wei-Guo
Sci Rep, 2015-03-04;5(0):8733.
Species: Rat
Sample Types: BALF
-
The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2.
Sci Rep, 2015-03-04;5(0):8713.
Species: Rat
Sample Types: Serum
-
Development of an equine groove model to induce metacarpophalangeal osteoarthritis: a pilot study on 6 horses.
Authors: Maninchedda U, Lepage O, Gangl M, Hilairet S, Remandet B, Meot F, Penarier G, Segard E, Cortez P, Jorgensen C, Steinberg R
PLoS ONE, 2015-02-13;10(2):e0115089.
Species: Equine
Sample Types: Synovial Fluid
-
Regulated expression of PTPRJ by COX-2/PGE2 axis in endothelial cells.
Authors: Xu X, Lan W, Jin X, Wang B, Yan H, Chen X, Lai X, Zhang L, Zhang X, Li Z
PLoS ONE, 2014-12-22;9(12):e114996.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibitory effects of benzaldehyde derivatives from the marine fungus Eurotium sp. SF-5989 on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages.
Authors: Kim K, Cui X, Lee D, Ko W, Sohn J, Yim J, An R, Kim Y, Oh H
Int J Mol Sci, 2014-12-19;15(12):23749-65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Pheophytin a inhibits inflammation via suppression of LPS-induced nitric oxide synthase-2, prostaglandin E2, and interleukin-1beta of macrophages.
Authors: Lin C, Lee C, Chang Y, Wang H, Chen C, Chen Y
Int J Mol Sci, 2014-12-09;15(12):22819-34.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Liver myofibroblasts from hepatitis B related liver failure patients may regulate natural killer cell function via PGE2.
Authors: Zhang, Min, Wang, Fenglan, Chong, Yutian, Tai, Qiang, Zhao, Qiyi, Zheng, Yubao, Peng, Liang, Lin, Shumei, Gao, Zhiliang
J Transl Med, 2014-11-04;12(1):308.
Species: Human
Sample Types: Cell Culture Supernates
-
Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane.
Authors: Chowdhury B, David A, Thrasivoulou C, Becker D, Bader D, Chowdhury T
Placenta, 2014-09-19;35(12):1057-64.
Species: Human
Sample Types: Cell Culture Supernates
-
NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions.
Authors: Bowers L, Maximo I, Brenner A, Beeram M, Hursting S, Price R, Tekmal R, Jolly C, deGraffenried L
Cancer Res, 2014-08-15;74(16):4446-57.
Species: Human
Sample Types: Cell Culture Supernates
-
A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging.
Authors: Yu K, Lee J, Kim H, Hong I, Choi S, Seo Y, Kang I, Kim J, Lee B, Lee S, Kurtz A, Seo K, Kang K
PLoS ONE, 2014-08-04;9(8):e102426.
Species: Human
Sample Types: Cell Culture Supernates
-
Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice.
Authors: Li J, Li F, Wei D, Jia W, Kang J, Stefanovic-Racic M, Dai Y, Zhao A
Mol Endocrinol, 2014-06-30;28(8):1316-28.
Species: Mouse
Sample Types: Serum
-
Interference of Ca(2)(+) with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells.
Authors: Otte A, Rauprich F, von der Ohe J, Hillemanns P, Hass R
Int J Oncol, 2014-06-24;45(3):1151-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
Authors: Annamanedi M, Kalle A
PLoS ONE, 2014-06-20;9(6):e99285.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lysosomal phospholipase A2: a novel player in host immunity to Mycobacterium tuberculosis.
Authors: Schneider B, Behrends J, Hagens K, Harmel N, Shayman J, Schaible U
Eur J Immunol, 2014-06-11;44(8):2394-404.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
Authors: Huang B, Lin C, Chen Y, Kao S
Mol Med Rep, 2014-06-05;10(2):1077-83.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dose-response of superparamagnetic iron oxide labeling on mesenchymal stem cells chondrogenic differentiation: a multi-scale in vitro study.
Authors: Roeder E, Henrionnet C, Goebel J, Gambier N, Beuf O, Grenier D, Chen B, Vuissoz P, Gillet P, Pinzano A
PLoS ONE, 2014-05-30;9(5):e98451.
Species: Human
Sample Types: Cell Culture Supernates
-
TREM-1 is induced in tumor associated macrophages by cyclo-oxygenase pathway in human non-small cell lung cancer.
Authors: Yuan, Zhihong, Mehta, Hiren J, Mohammed, Kamal, Nasreen, Najmunis, Roman, Robert, Brantly, Mark, Sadikot, Ruxana T
PLoS ONE, 2014-05-19;9(5):e94241.
Species: Human
Sample Types: Tissue Homogenates
-
Vaccine-induced myeloid cell population dampens protective immunity to SIV.
Authors: Sui Y, Hogg A, Wang Y, Frey B, Yu H, Xia Z, Venzon D, McKinnon K, Smedley J, Gathuka M, Klinman D, Keele B, Langermann S, Liu L, Franchini G, Berzofsky J
J Clin Invest, 2014-05-16;124(6):2538-49.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Plasma
-
Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease.
Authors: Arab H, Al-Shorbagy M, Abdallah D, Nassar N
PLoS ONE, 2014-05-15;9(5):e97193.
Species: Rat
Sample Types: Tissue Homogenates
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Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
Autophagy, 2014-05-14;10(7):1301-15.
Species: Mouse
Sample Types: Cell Culture Supernates
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Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma.
Authors: Ren G, Hu J, Wang R, Han W, Zhao M, Zhou G, Zhang C, Zhang Z
Oncol Rep, 2014-04-11;31(6):2804-10.
Species: Human
Sample Types: Cell Culture Supernates
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A pilot study investigating early postoperative changes of plasma polyunsaturated fatty acids after laparoscopic sleeve gastrectomy.
Authors: Aslan M, Aslan I, Ozcan F, Eryilmaz R, Ensari C, Bilecik T
Lipids Health Dis, 2014-04-03;13(0):62.
Species: Human
Sample Types: Serum
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Leishmanial lipid suppresses the bacterial endotoxin-induced inflammatory response with attenuation of tissue injury in sepsis.
Authors: Chatterjee N, Das S, Bose D, Banerjee S, Jha T, Saha K
J Leukoc Biol, 2014-04-02;96(2):325-36.
Species: Mouse
Sample Types: Cell Culture Supernates
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Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth.
Authors: Mogami, Haruta, Keller, Patrick, Shi, Haolin, Word, R Ann
J Biol Chem, 2014-03-20;289(19):13295-307.
Species: Human
Sample Types: Cell Culture Supernates
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Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
J Biol Chem, 2014-03-13;289(16):11522-35.
Species: Mouse
Sample Types: Cell Culture Supernates
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Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure.
Authors: Zhang M, Ye Y, Wang F, Zhu J, Zhao Q, Zheng Y, Gu Y, Xie C, Huang Z, Tai Q, Chong Y, Gao Z
2014-03-06;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase.
Authors: Luna-Gomes T, Filardy A, Rocha J, Decote-Ricardo D, LaRocque-de-Freitas I, Morrot A, Bozza P, Castro-Faria-Neto H, DosReis G, Nunes M, Freire-de-Lima C
PLoS ONE, 2014-03-05;9(3):e90582.
Species: Mouse
Sample Types: Cell Culture Supernates
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Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source.
Authors: Carrade Holt D, Wood J, Granick J, Walker N, Clark K, Borjesson D
Stem Cells Dev, 2014-03-04;23(11):1258-65.
Species: Equine
Sample Types: Cell Culture Supernates
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Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells.
Authors: Yamahara, Kenichi, Harada, Kazuhiko, Ohshima, Makiko, Ishikane, Shin, Ohnishi, Shunsuke, Tsuda, Hidetosh, Otani, Kentaro, Taguchi, Akihiko, Soma, Toshihir, Ogawa, Hiroyasu, Katsuragi, Shinji, Yoshimatsu, Jun, Harada-Shiba, Mariko, Kangawa, Kenji, Ikeda, Tomoaki
PLoS ONE, 2014-02-14;9(2):e88319.
Species: Human
Sample Types: Cell Culture Supernates
-
Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
Authors: Sidney L, Kirkham G, Buttery L
Stem Cells Dev, 2014-01-23;23(6):605-17.
Species: Mouse
Sample Types: Cell Culture Supernates
-
From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract.
Authors: Ebeling, Sandra, Naumann, Katrin, Pollok, Simone, Wardecki, Tina, Vidal-Y-Sy, Sabine, Nascimento, Juliana, Boerries, Melanie, Schmidt, Gudula, Brandner, Johanna, Merfort, Irmgard
PLoS ONE, 2014-01-22;9(1):e86147.
Species: Human
Sample Types: Cell Culture Supernates
-
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
Authors: Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S
EMBO Mol Med, 2014-01-08;6(3):322-34.
Species: Human
Sample Types: Cell Culture Supernates
-
AMPK in the small intestine in normal and pathophysiological conditions.
Authors: Harmel E, Grenier E, Bendjoudi Ouadda A, El Chebly M, Ziv E, Beaulieu J, Sane A, Spahis S, Laville M, Levy E
Endocrinology, 2014-01-01;155(3):873-88.
Species: Rat
Sample Types: Tissue Homogenates
-
Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation.
Authors: Jung, Eunsun, Lee, Jung-A, Shin, Seoungwo, Roh, Kyung-Ba, Kim, Jang-Hyu, Park, Deokhoon
Molecules, 2013-12-16;18(12):15724-36.
Species: Human
Sample Types: Cell Culture Supernates
-
Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia.
Authors: Conforti A, Biagini S, Del Bufalo F, Sirleto P, Angioni A, Starc N, Li Pira G, Moretta F, Proia A, Contoli B, Genovese S, Ciardi C, Avanzini M, Rosti V, Lo-Coco F, Locatelli F, Bernardo M
PLoS ONE, 2013-11-07;8(11):e76989.
Species: Human
Sample Types: Cell Culture Supernates
-
LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy.
Authors: Aslan M, Ozcan F, Aslan I, Yucel G
Lipids Health Dis, 2013-11-06;12(0):169.
Species: Human
Sample Types: Serum
-
Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.
Authors: Delaine-Smith, Robin M, Sittichokechaiwut, Anuphan, Reilly, Gwendole
FASEB J, 2013-10-04;28(1):430-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate.
Authors: Wan, Rong, Jin, Lai, Zhu, Chao, Liu, Yunxin, Li, Li, Guo, Rui, Li, Shengnan
Endocrinology, 2013-09-24;154(12):4663-74.
Species: Rat
Sample Types: Plasma
-
Diterpenylquinone hybrids: synthesis and assessment of gastroprotective mechanisms of action in human cells.
Authors: Theoduloz, Cristina, Bravo, Ivanna, Pertino, Mariano, Schmeda-Hirschmann, Guillerm
Molecules, 2013-09-10;18(9):11044-66.
Species: Human
Sample Types: Cell Culture Supernates
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Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.
Authors: Iachininoto M, Nuzzolo E, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S
Molecules, 2013-08-22;18(9):10132-45.
Species: Human
Sample Types: Cell Culture Supernates
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Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2.
Authors: Manferdini C, Maumus M, Gabusi E, Piacentini A, Filardo G, Peyrafitte J, Jorgensen C, Bourin P, Fleury-Cappellesso S, Facchini A, Noel D, Lisignoli G
Arthritis Rheum, 2013-05-01;65(5):1271-81.
Species: Human
Sample Types: Cell Culture Supernates
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Antagonizing effects and mechanisms of afzelin against UVB-induced cell damage.
Authors: Shin S, Jung E, Kim S, Kim J, Kim E, Lee J, Park D
PLoS ONE, 2013-04-23;8(4):e61971.
Species: Human
Sample Types: Cell Culture Supernates
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MicroRNA-146a negatively regulates the immunoregulatory activity of bone marrow stem cells by targeting prostaglandin E2 synthase-2.
Authors: Matysiak, Mariola, Fortak-Michalska, Maria, Szymanska, Bozena, Orlowski, Wojciech, Jurewicz, Anna, Selmaj, Krzyszto
J Immunol, 2013-04-15;190(10):5102-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner.
Authors: Mace T, Ameen Z, Collins A, Wojcik S, Mair M, Young G, Fuchs J, Eubank T, Frankel W, Bekaii-Saab T, Bloomston M, Lesinski G
Cancer Res, 2013-03-20;73(10):3007-18.
Species: Human
Sample Types: Cell Culture Supernates
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Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
J Biol Chem, 2012-11-26;288(3):1953-66.
Species: Human
Sample Types: Cell Culture Supernates
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Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice.
Authors: Herranz S, Traves P, Luque A, Hortelano S
Oncoimmunology, 2012-11-01;1(8):1227-1238.
Species: Mouse
Sample Types: Cell Culture Supernates
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Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
Stem Cells, 2012-10-01;30(10):2283-96.
Species: Mouse
Sample Types: Cell Culture Supernates
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Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells.
Authors: Zong Y, Sun L, Liu B, Deng Y, Zhan D, Chen Y, He Y, Liu J, Zhang Z, Sun J, Lu D
PLoS ONE, 2012-08-31;7(8):e44107.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
Authors: Wang JH, Shih KS, Liou JP, Wu YW, Chang AS, Wang KL, Tsai CL, Yang CR
PLoS ONE, 2012-02-16;7(2):e31368.
Species: Human
Sample Types: Cell Culture Supernates
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Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.
Authors: Liu L, Cao Z, Chen J
J. Biol. Chem., 2012-02-16;287(15):11899-910.
Species: Human
Sample Types: Serum
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Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012-01-18;7(1):e30005.
Species: Mouse
Sample Types: Tissue Homogenates
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Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function.
Authors: Abdelrazik H, Spaggiari GM, Chiossone L, Moretta L
Eur. J. Immunol., 2011-10-18;41(11):3281-90.
Species: Human
Sample Types: Cell Culture Supernates
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Evidence for regulated interleukin-4 expression in chondrocyte-scaffolds under in vitro inflammatory conditions.
Authors: Rai MF, Graeve T, Twardziok S, Schmidt MF
PLoS ONE, 2011-10-03;6(10):e25749.
Species: Canine
Sample Types: Cell Culture Supernates
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Serotonin activates dendritic cell function in the context of gut inflammation.
Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
Am. J. Pathol., 2011-02-01;178(2):662-71.
Species: Mouse
Sample Types: Tissue Homogenates
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Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties.
Authors: Oliveira CJ, Sa-Nunes A, Francischetti IM, Carregaro V, Anatriello E, Silva JS, Santos IK, Ribeiro JM, Ferreira BR
J. Biol. Chem., 2011-01-26;286(13):10960-9.
Species: Mouse, Tick
Sample Types: Cell Culture Supernates, Saliva
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Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death.
Authors: Zhao Z, Liu N, Huang J, Lu PH, Xu XM
J. Neurochem., 2011-01-19;116(6):1057-65.
Species: Rat
Sample Types: Cell Culture Supernates
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Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.
Authors: Verma S, Kumar M, Nerurkar VR
J. Gen. Virol., 2010-11-24;92(0):507-15.
Species: Human
Sample Types: Cell Culture Supernates
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Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity.
Authors: Nakajima S, Honda T, Sakata D, Egawa G, Tanizaki H, Otsuka A, Moniaga CS, Watanabe T, Miyachi Y, Narumiya S, Kabashima K
J. Immunol., 2010-04-16;184(10):5595-603.
Species: Mouse
Sample Types: Cell Culture Supernates
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Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
Authors: Rydkina E, Turpin LC, Sahni SK
Infect. Immun., 2010-04-12;78(6):2599-606.
Species: Human
Sample Types: Cell Culture Supernates
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Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice.
Authors: Niwa S, Urtz N, Baumruker T, Billich A, Bornancin F
Lipids Health Dis, 2010-01-06;9(0):1.
Species: Mouse
Sample Types: BALF
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Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
Authors: Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K
J. Bone Miner. Res., 2009-12-01;24(12):2056-65.
Species: Mouse
Sample Types: Serum
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P2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells.
Authors: Degagne E, Grbic DM, Dupuis AA, Lavoie EG, Langlois C, Jain N, Weisman GA, Sevigny J, Gendron FP
J. Immunol., 2009-09-04;183(7):4521-9.
Species: Human
Sample Types: Cell Culture Supernates
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Therapeutic effect of Aralia cordata extracts on cartilage protection in collagenase-induced inflammatory arthritis rabbit model.
Authors: Park DS, Huh JE, Baek YH
J Ethnopharmacol, 2009-07-18;125(2):207-17.
Species: Rabbit
Sample Types: Serum
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Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells.
Authors: Luna C, Li G, Qiu J, Challa P, Epstein DL, Gonzalez P
Invest. Ophthalmol. Vis. Sci., 2009-07-15;50(12):5805-10.
Species: Porcine
Sample Types: Cell Culture Supernates
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Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.
Authors: Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J
Blood, 2009-07-08;114(15):3181-90.
Species: Human
Sample Types: Cell Culture Supernates
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Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming.
Authors: Highfill SL, Kelly RM, O'Shaughnessy MJ, Zhou Q, Xia L, Panoskaltsis-Mortari A, Taylor PA, Tolar J, Blazar BR
Blood, 2009-05-20;114(3):693-701.
Species: Mouse
Sample Types: Cell Culture Supernates
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Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines.
Authors: Gadgeel SM, Ali S, Philip PA, Wozniak A, Sarkar FH
Cancer, 2009-05-15;115(10):2165-76.
Species: Human
Sample Types: Cell Culture Supernates
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In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland.
Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM
Brain Behav. Immun., 2009-05-07;23(7):945-57.
Species: Rat
Sample Types: Tissue Homogenates
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Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha.
Authors: Lee SH, Kim MH, Han HJ
Am. J. Physiol., Cell Physiol., 2009-04-01;297(1):C207-16.
Species: Mouse
Sample Types: Cell Culture Supernates
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In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb.
Authors: Souza Mdo C, Beserra AM, Martins DC, Real VV, Santos RA, Rao VS, Silva RM, Martins DT
J Ethnopharmacol, 2009-03-27;123(3):452-8.
Species: Rat
Sample Types: Tissue Homogenates
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Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
J Ethnopharmacol, 2009-02-03;122(3):473-7.
Species: Mouse
Sample Types: Cell Culture Supernates
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Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
Am. J. Respir. Crit. Care Med., 2009-01-08;179(6):474-83.
Species: Mouse
Sample Types: BALF
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Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Authors: Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S, Libra M
Clin. Cancer Res., 2008-11-15;14(22):7470-80.
Species: Human
Sample Types: Plasma
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Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS
J. Immunol., 2008-10-15;181(8):5360-7.
Species: Mouse
Sample Types: Tissue Homogenates
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Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
Eur. J. Immunol., 2008-10-01;38(10):2751-61.
Species: Mouse
Sample Types: BALF
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Protective effects of butanol fraction from Betula Platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis.
Authors: Huh JE, Baek YH, Kim YJ, Lee JD, Choi DY, Park DS
J Ethnopharmacol, 2008-09-04;123(3):515-21.
Species: Rabbit
Sample Types: Serum
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Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells.
Authors: Reddi D, Bostanci N, Hashim A, Aduse-Opoku J, Curtis MA, Hughes FJ, Belibasakis GN
Microbes Infect., 2008-08-26;10(14):1459-68.
Species: Mouse
Sample Types: Cell Culture Supernates
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Effect of intensive atorvastatin therapy on prostaglandin E2 levels and metalloproteinase-9 activity in the plasma of patients with non-ST-elevation acute coronary syndrome.
Authors: Gomez-Hernandez A, Sanchez-Galan E, Ortego M, Martin-Ventura JL, Blanco-Colio LM, Tarin-Vicente N, Jimenez-Nacher JJ, Lopez-Bescos L, Egido J, Tuñón J
Am. J. Cardiol., 2008-04-22;102(1):12-8.
Species: Human
Sample Types: Plasma
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Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
Biochem. Biophys. Res. Commun., 2008-04-22;371(3):361-5.
Species: Mouse
Sample Types: Cell Culture Supernates
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Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling.
Authors: Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F
Stem Cells, 2007-10-25;26(1):279-89.
Species: Human
Sample Types: Cell Culture Supernates
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Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage.
Authors: Tam CL, Hofbauer M, Towle CA
Biochem. Pharmacol., 2007-08-07;74(11):1636-41.
Species: Bovine
Sample Types: Cell Culture Supernates
-
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
J. Immunol., 2007-08-01;179(3):1855-63.
Species: Mouse
Sample Types: BALF
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Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N
J. Immunol., 2007-07-01;179(1):639-46.
Species: Mouse
Sample Types: Serum
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CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats.
Authors: Machado RR, Soares DM, Proudfoot AE, Soares DM, Proudfoot AE, Souza GE, Souza GE
Brain Res., 2007-06-09;1161(0):21-31.
Species: Rat
Sample Types: CSF
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5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
Authors: Nandi J, Saud B, Zinkievich JM, Palma DT, Levine RA
Dig. Dis. Sci., 2007-05-15;53(1):123-32.
Species: Rat
Sample Types: Tissue Homogenates
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Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression.
Authors: Hennerbichler A, Fermor B, Hennerbichler D, Weinberg JB, Guilak F
Biochem. Biophys. Res. Commun., 2007-05-14;358(4):1047-53.
Species: Porcine
Sample Types: Cell Culture Supernates
FAQs
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How should the indomethacin be prepared, prior to being added to the serum or plasma collection tubes?
First, dissolve indomethacin (Tocris cat # 1708) in ethanol to 10 mg/mL. Then, dilute indomethacin solution 1:50 in 1X PBS (to 0.2 mg/mL). Finally, inject 0.2 mg/mL indomethacin solution into vacutainer tube immediately following blood draw, to a final concentration of 10 μg/mL.
Reviews for Prostaglandin E2 Parameter Assay Kit
Average Rating: 3.6 (Based on 10 Reviews)
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This kit is really great and easy to use!
It performed really good and repeatable.
I used RAW 264.7 cells and found great variability within technical replicates. The image shows the variability (across row) of the standards and I was also not able to get a usable standard curve.
***Bio-Techne Response: Thank you for reviewing our product. We are sorry to that that this product did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction.***
High variability between replicates. Perhaps the most common issue with the kit is the requirement to complete the assay with a specific microplate shaker- which is how the assay was developed and QC tested, this is a horizontal orbital microplate shaker (0.12 inches or 3mm orbit) set at 500 ± 50 rpm.
***Bio-Techne Response: Thank you for reviewing our product. We are sorry to that that this product did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction.***
I had trouble replicating the standard curve
***Bio-Techne Response: Thank you for reviewing our product. We are sorry to that that this product did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction.***
Very easy to use, reliable results