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PRX 07034

Catalog #: 6748 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6748/10
6748/50
PRX 07034 | CAS No. 903580-39-2 | 5-HT6 Receptor Antagonists
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Description: Potent and selective 5-HT6 antagonist

Chemical Name: N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-2-(methylsulfonyl)-5-(piperazin-1-yl)aniline hydrochloride

Purity: ≥98%

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Biological Activity

PRX 07034 is a potent and selective 5-HT6 receptor antagonist (IC50 = 19 nM, Ki = 4 - 8 nM). Enhances working memory in rats.

Technical Data

M.Wt:
490.44
Formula:
C21H28ClN3O4S.HCl
Solubility:
Soluble to 20 mM in water with gentle warming and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
903580-39-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. The effects of PRX-07034, a novel 5-HT6 antagonist, on cognitive flexibility and working memory in rats.
    Mohler et al.
    Psychopharmacology (Berl)., 2012;220:687

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