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Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Catalog #: 350-NS
174 Citations 4 Reviews Datasheet / COA / SDS

Carrier Free

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350-NS-010/CF
350-NS-050/CF

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Catalog # Availability Size / Price Qty
350-NS-010
350-NS-050
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Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Bioactivity
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Product Details
Citations (174)
FAQs
Reviews (4)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL). The ED50 for this effect is 3‑9 ng/mL. Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR4. The ED50 for this effect is 0.15‑0.6 ng/mL.
Source
E. coli-derived CXCL12/SDF-1 alpha protein
Lys22-Lys89
Accession #
P48061
N-terminal Sequence
Analysis
Lys22
Predicted Molecular Mass
8.0 kDa
SDS-PAGE
7 kDa, reducing conditions.

Product Datasheets

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350-NS (with carrier)

Product Datasheet
COA
SDS

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350-NS/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

350-NS

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

350-NS/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

Bioactivity Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Bioactivity View Larger

Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (Catalog # 350-NS) chemoattracts the BaF3 mouse pro-B cells transfected with human CXCR4. The ED50 for this effect is 0.15-0.6 ng/mL.

SDS-PAGE Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha SDS-PAGE View Larger

1 μg/lane of Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CXCL12/SDF-1 alpha

SDF-1 alpha and SDF-1 beta are the first cytokines initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line.
SDF-1 alpha  and SDF-1 beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. SDF-1 alpha and SDF-1 beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 beta and absent from SDF-1 alpha. The amino acid sequence of SDF-1/PBSF identified the protein to be a member of the chemokine alpha subfamily that lacks the ELR domain. Unlike other known chemokine alpha and beta subfamily members that cluster on chromosomes 4 and 17, respectively, SDF-1/PBSF was mapped to chromosome 10q11.1. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF has been found to be a chemoattractant for T-lymphocytes and monocytes, but not neutrophils. SDF-1/PBSF was shown to be a ligand for CXCR4 (fusin/LESTR) receptor that functions as a co-receptor for lymphocyte-tropic HIV-1 strains. SDF-1/PBSF has been found to be a powerful inhibitor of infection by lymphocyte-tropic HIV-1 strains.

References
  1. Tashiro, K. et al. (1993) Science 261:600.
  2. Bleul, C. et al. (1996) Nature 382:829.
  3. Oberlin, E. et al. (1996) Nature 382:833.
Entrez Gene IDs
6387 (Human); 20315 (Mouse); 493806 (Feline)
Alternate Names
CXCL12 chemokine (C-X-C motif) ligand 12; CXCL12/SDF-1 alpha; IRH; PBSF; SCYB12; SDF1 alpha; SDF1; SDF1a; SDF1B; TLSF; TPAR1

Citations for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

174 Citations: Showing 1 - 10
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  1. An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
    Authors: Toffali, L;D'Ulivo, B;Giagulli, C;Montresor, A;Zenaro, E;Delledonne, M;Rossato, M;Iadarola, B;Sbarbati, A;Bernardi, P;Angelini, G;Rossi, B;Lopez, N;Linke, WA;Unger, A;Di Silvestre, D;Benazzi, L;De Palma, A;Motta, S;Constantin, G;Mauri, P;Laudanna, C;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Stem cell-nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy
    Authors: YH Lai, CY Su, HW Cheng, CY Chu, LB Jeng, CS Chiang, WC Shyu, SY Chen
    Nature Communications, 2023-01-18;14(1):285.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer
    Authors: M Tobiume, A Mitsuhashi, A Saijo, H Ogino, T Afroj, H Ogawa, H Goto, S Sato, A Abe, K Haji, R Ozaki, H Takizawa, Y Nishioka
    Oncology Letters, 2022-09-30;24(5):417.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. SDF?1alpha/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways in�vitro
    Authors: X Yuan, H Wu, X Li, L Chen, Y Xiao, Z Chen, G Liu, P Lu
    Molecular Medicine Reports, 2022-08-10;26(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. DOCK2 is involved in the host genetics and biology of severe COVID-19
    Authors: H Namkoong, R Edahiro, T Takano, H Nishihara, Y Shirai, K Sonehara, H Tanaka, S Azekawa, Y Mikami, H Lee, T Hasegawa, K Okudela, D Okuzaki, D Motooka, M Kanai, T Naito, K Yamamoto, QS Wang, R Saiki, R Ishihara, Y Matsubara, J Hamamoto, H Hayashi, Y Yoshimura, N Tachikawa, E Yanagita, T Hyugaji, E Shimizu, K Katayama, Y Kato, T Morita, K Takahashi, N Harada, T Naito, M Hiki, Y Matsushita, H Takagi, R Aoki, A Nakamura, S Harada, H Sasano, H Kabata, K Masaki, H Kamata, S Ikemura, S Chubachi, S Okamori, H Terai, A Morita, T Asakura, J Sasaki, H Morisaki, Y Uwamino, K Nanki, S Uchida, S Uno, T Nishimura, T Ishiguro, T Isono, S Shibata, Y Matsui, C Hosoda, K Takano, T Nishida, Y Kobayashi, Y Takaku, N Takayanagi, S Ueda, A Tada, M Miyawaki, M Yamamoto, E Yoshida, R Hayashi, T Nagasaka, S Arai, Y Kaneko, K Sasaki, E Tagaya, M Kawana, K Arimura, K Takahashi, T Anzai, S Ito, A Endo, Y Uchimura, Y Miyazaki, T Honda, T Tateishi, S Tohda, N Ichimura, K Sonobe, CT Sassa, J Nakajima, Y Nakano, Y Nakajima, R Anan, R Arai, Y Kurihara, Y Harada, K Nishio, T Ueda, M Azuma, R Saito, T Sado, Y Miyazaki, R Sato, Y Haruta, T Nagasaki, Y Yasui, Y Hasegawa, Y Mutoh, T Kimura, T Sato, R Takei, S Hagimoto, Y Noguchi, Y Yamano, H Sasano, S Ota, Y Nakamori, K Yoshiya, F Saito, T Yoshihara, D Wada, H Iwamura, S Kanayama, S Maruyama, T Yoshiyama, K Ohta, H Kokuto, H Ogata, Y Tanaka, K Arakawa, M Shimoda, T Osawa, H Tateno, I Hase, S Yoshida, S Suzuki, M Kawada, H Horinouchi, F Saito, K Mitamura, M Hagihara, J Ochi, T Uchida, R Baba, D Arai, T Ogura, H Takahashi, S Hagiwara, G Nagao, S Konishi, I Nakachi, K Murakami, M Yamada, H Sugiura, H Sano, S Matsumoto, N Kimura, Y Ono, H Baba, Y Suzuki, S Nakayama, K Masuzawa, S Namba, K Suzuki, Y Naito, YC Liu, A Takuwa, F Sugihara, JB Wing, S Sakakibara, N Hizawa, T Shiroyama, S Miyawaki, Y Kawamura, A Nakayama, H Matsuo, Y Maeda, T Nii, Y Noda, T Niitsu, Y Adachi, T Enomoto, S Amiya, R Hara, Y Yamaguchi, T Murakami, T Kuge, K Matsumoto, Y Yamamoto, M Yamamoto, M Yoneda, T Kishikawa, S Yamada, S Kawabata, N Kijima, M Takagaki, N Sasa, Y Ueno, M Suzuki, N Takemoto, H Eguchi, T Fukusumi, T Imai, M Fukushima, H Kishima, H Inohara, K Tomono, K Kato, M Takahashi, F Matsuda, H Hirata, Y Takeda, H Koh, T Manabe, Y Funatsu, F Ito, T Fukui, K Shinozuka, S Kohashi, M Miyazaki, T Shoko, M Kojima, T Adachi, M Ishikawa, K Takahashi, T Inoue, T Hirano, K Kobayashi, H Takaoka, K Watanabe, N Miyazawa, Y Kimura, R Sado, H Sugimoto, A Kamiya, N Kuwahara, A Fujiwara, T Matsunaga, Y Sato, T Okada, Y Hirai, H Kawashima, A Narita, K Niwa, Y Sekikawa, K Nishi, M Nishitsuji, M Tani, J Suzuki, H Nakatsumi, T Ogura, H Kitamura, E Hagiwara, K Murohashi, H Okabayashi, T Mochimaru, S Nukaga, R Satomi, Y Oyamada, N Mori, T Baba, Y Fukui, M Odate, S Mashimo, Y Makino, K Yagi, M Hashiguchi, J Kagyo, T Shiomi, S Fuke, H Saito, T Tsuchida, S Fujitani, M Takita, D Morikawa, T Yoshida, T Izumo, M Inomata, N Kuse, N Awano, M Tone, A Ito, Y Nakamura, K Hoshino, J Maruyama, H Ishikura, T Takata, T Odani, M Amishima, T Hattori, Y Shichinohe, T Kagaya, T Kita, K Ohta, S Sakagami, K Koshida, K Hayashi, T Shimizu, Y Kozu, H Hiranuma, Y Gon, N Izumi, K Nagata, K Ueda, R Taki, S Hanada, K Kawamura, K Ichikado, K Nishiyama, H Muranaka, K Nakamura, N Hashimoto, K Wakahara, K Sakamoto, N Omote, A Ando, N Kodama, Y Kaneyama, S Maeda, T Kuraki, T Matsumoto, K Yokote, TA Nakada, R Abe, T Oshima, T Shimada, M Harada, T Takahashi, H Ono, T Sakurai, T Shibusawa, Y Kimizuka, A Kawana, T Sano, C Watanabe, R Suematsu, H Sageshima, A Yoshifuji, K Ito, S Takahashi, K Ishioka, M Nakamura, M Masuda, A Wakabayash, H Watanabe, S Ueda, M Nishikawa, Y Chihara, M Takeuchi, K Onoi, J Shinozuka, A Sueyoshi, Y Nagasaki, M Okamoto, S Ishihara, M Shimo, Y Tokunaga, Y Kusaka, T Ohba, S Isogai, A Ogawa, T Inoue, S Fukuyama, Y Eriguchi, A Yonekawa, K Kan-O, K Matsumoto, K Kanaoka, S Ihara, K Komuta, Y Inoue, S Chiba, K Yamagata, Y Hiramatsu, H Kai, K Asano, T Oguma, Y Ito, S Hashimoto, M Yamasaki, Y Kasamatsu, Y Komase, N Hida, T Tsuburai, B Oyama, M Takada, H Kanda, Y Kitagawa, T Fukuta, T Miyake, S Yoshida, S Ogura, S Abe, Y Kono, Y Togashi, H Takoi, R Kikuchi, S Ogawa, T Ogata, S Ishihara, A Kanehiro, S Ozaki, Y Fuchimoto, S Wada, N Fujimoto, K Nishiyama, M Terashima, S Beppu, K Yoshida, O Narumoto, H Nagai, N Ooshima, M Motegi, A Umeda, K Miyagawa, H Shimada, M Endo, Y Ohira, M Watanabe, S Inoue, A Igarashi, M Sato, H Sagara, A Tanaka, S Ohta, T Kimura, Y Shibata, Y Tanino, T Nikaido, H Minemura, Y Sato, Y Yamada, T Hashino, M Shinoki, H Iwagoe, H Takahashi, K Fujii, H Kishi, M Kanai, T Imamura, T Yamashita, M Yatomi, T Maeno, S Hayashi, M Takahashi, M Kuramochi, I Kamimaki, Y Tominaga, T Ishii, M Utsugi, A Ono, T Tanaka, T Kashiwada, K Fujita, Y Saito, M Seike, H Watanabe, H Matsuse, N Kodaka, C Nakano, T Oshio, T Hirouchi, S Makino, M Egi, Biobank Ja, Y Omae, Y Nannya, T Ueno, K Katayama, M Ai, Y Fukui, A Kumanogoh, T Sato, N Hasegawa, K Tokunaga, M Ishii, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Y Okada
    Nature, 2022-08-08;609(7928):754-760.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Inflammation down regulates stromal cell-derived factor 1alpha in the early phase of pulpitis
    Authors: S Leng, L Liu, W Xu, F Yang, J Du, L Ye, D Huang, L Zhang
    Cytokine, 2022-08-02;158(0):155983.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration
    Authors: M Mastrogiov, P Vargas, T Rose, C Cuche, E Esposito, M Juzans, H Laude, A Schneider, M Bernard, S Goyard, C Renaudat, MN Ungeheuer, J Delon, A Alcover, V Di Bartolo
    Science Advances, 2022-04-13;8(15):eabl5942.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia
    Authors: TA Burley, A Hesketh, G Bucca, E Kennedy, EE Ladikou, BP Towler, S Mitchell, CP Smith, C Fegan, R Johnston, A Pepper, C Pepper
    Cancers, 2022-03-22;14(7):.
    Species: Human
    Sample Types: Whole Cell
    Applications: Bioassay
  9. Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing
    Authors: J Xu, J Hu, S Idlett-Ali, L Zhang, K Caples, S Peddibhotl, M Reeves, C Zgheib, S Malany, KW Liechty
    International Journal of Molecular Sciences, 2022-02-16;23(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Galphai signaling
    Authors: ML Capitano, Y Sammour, J Ropa, M Legendre, N Mor-Vaknin, DM Markovitz
    Journal of leukocyte biology, 2022-02-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis
    Authors: C Fielding, A García-Gar, C Korn, S Gadomski, Z Fang, JL Reguera, JA Pérez-Simó, B Göttgens, S Méndez-Fer
    Nature Communications, 2022-01-27;13(1):543.
    Species: Mouse
    Sample Types: Bone Marrow Lavage Fluid
    Applications: ELISA Control
  12. Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells.
    Authors: Wellemans V, Benhassou H, Fuselier E, Bellesort F, Dury S, Lebargy F, Dormoy V, Fichel C, Naour R, Gounni A, Lamkhioued B
    iScience, 2021-11-14;24(12):103433.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
    Authors: T Radaszkiew, M Nosková, K Gömöryová, O Vondálová, KA Radaszkiew, M Picková, R Víchová, T Gybe?, K Kaiser, L Demková, L Ku?erová, T Bárta, D Pot?šil, Z Zdráhal, K Sou?ek, V Bryja
    Elife, 2021-10-27;10(0):.
    Species: Human
    Sample Types: Transduced Whole Cells
    Applications: Bioassay
  14. Dual role for CXCL12 signaling in semilunar valve development
    Authors: LA Ridge, D Kewbank, D Schütz, R Stumm, PJ Scambler, S Ivins
    Cell Reports, 2021-08-24;36(8):109610.
    Species: Mouse
    Sample Types: Organoid
    Applications: Bioassay
  15. VLA-4 Induces Chemoresistance of T Cell Acute Lymphoblastic Leukemia Cells via PYK2-Mediated Drug Efflux
    Authors: S Berrazouan, A Doucet, M Boisvert, F Barabé, F Aoudjit
    Cancers, 2021-07-14;13(14):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression
    Authors: Y Fu, Z Zhang, Z Yang, Y Jiang, X Han, J Xu, Z Chu, H Ding, S He, H Shang
    Cell Reports, 2021-07-13;36(2):109344.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. miR-126-3p is essential for CXCL12-induced angiogenesis
    Authors: K Bassand, L Metzinger, M Naïm, N Mouhoubi, O Haddad, V Assoun, N Zaïdi, O Sainte-Cat, A Butt, E Guyot, O Oudar, C Laguillier, A Sutton, N Charnaux, V Metzinger-, H Hlawaty
    Journal of Cellular and Molecular Medicine, 2021-06-12;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  18. Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin &beta1-ILK-&beta-catenin-JUN axis
    Authors: A Yuzuriha, S Nakamura, N Sugimoto, S Kihara, M Nakagawa, T Yamamoto, K Sekiguchi, K Eto
    Stem Cell Research, 2021-03-16;53(0):102287.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer
    Authors: JY Kim, HJ Kim, CW Jung, TS Lee, EH Kim, MJ Park
    Cell Death & Disease, 2021-01-07;12(1):48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3
    Authors: W Feng, W Huang, J Chen, C Qiao, D Liu, X Ji, M Xie, T Zhang, Y Wang, M Sun, D Tian, D Fan, Y Nie, K Wu, L Xia
    Theranostics, 2021-01-01;11(6):2612-2633.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response
    Authors: D Biasci, M Smoragiewi, CM Connell, Z Wang, Y Gao, JED Thaventhir, B Basu, L Magiera, TI Johnson, L Bax, A Gopinathan, C Isherwood, FA Gallagher, M Pawula, I Hudecova, D Gale, N Rosenfeld, P Barmpounak, EC Popa, R Brais, E Godfrey, F Mir, FM Richards, DT Fearon, T Janowitz, DI Jodrell
    Proc Natl Acad Sci U S A, 2020-10-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
    Authors: A Fumagalli, J Heuninck, A Pizzoccaro, E Moutin, J Koenen, M Séveno, T Durroux, MP Junier, G Schlecht-L, F Bachelerie, D Schütz, R Stumm, MJ Smit, NC Guérineau, S Chaumont-D, P Marin
    Nat Commun, 2020-09-25;11(1):4855.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles
    Authors: PR Norden, Z Sun, GE Davis
    PLoS ONE, 2020-06-22;15(6):e0235116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1alpha
    Authors: J O'Dwyer, M Cullen, S Fattah, R Murphy, S Stefanovic, L Kovarova, M Pravda, V Velebny, A Heise, GP Duffy, SA Cryan
    Pharmaceutics, 2020-06-04;12(6):.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  25. Brief ex vivo Fas-ligand incubation attenuates GvHD without compromising stem cell graft performance
    Authors: H Levy-Baraz, L Shachnai-P, G Rodionov, A Saar, M Rosenzwaig, L Gez, A Rodin, N Marelly, M Abraham, I Mishalian, H Wildbaum, T Katz, Y Baar, S Yarkoni, R Bakimer-Kl, A Peled, T Zuckerman, J Stein
    Bone Marrow Transplant., 2020-05-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway
    Authors: J Lim, J Heo, H Ju, JW Shin, Y Kim, S Lee, HY Yu, CM Ryu, H Yun, S Song, KS Hong, HM Chung, HR Kim, JS Roe, K Choi, IG Kim, EM Jeong, DM Shin
    Sci Adv, 2020-04-15;6(16):eaba1334.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina
    Authors: H Cho, BL Macklin, YY Lin, L Zhou, MJ Lai, G Lee, S Gerecht, EJ Duh
    JCI Insight, 2020-03-26;5(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  28. A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer
    Authors: AA Chimote, VS Gawali, HS Newton, TM Wise-Drape, L Conforti
    Front Pharmacol, 2020-02-28;11(0):143.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Role and therapeutic effects of skeletal muscle-derived non-myogenic cells in a rat myocardial infarction model
    Authors: H Iseoka, S Miyagawa, A Saito, A Harada, Y Sawa
    Stem Cell Res Ther, 2020-02-18;11(1):69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. LRCH1 suppresses migration of CD4+ T cells and refers to disease activity in ulcerative colitis
    Authors: Y Wang, H Zhang, H He, K Ai, W Yu, X Xiao, Y Qin, L Zhang, H Xiong, G Zhou
    Int J Med Sci, 2020-02-17;17(5):599-608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Mitochondrial mass governs the extent of human T cell senescence
    Authors: LA Callender, EC Carroll, EA Bober, AN Akbar, E Solito, SM Henson
    Aging Cell, 2019-12-02;0(0):e13067.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Distinguishing human peripheral blood CD16+ myeloid cells based on phenotypic characteristics
    Authors: PD Fromm, PA Silveira, JL Hsu, MS Papadimitr, TH Lo, X Ju, F Kupresanin, A Romano, WH Hsu, CE Bryant, B Kong, E Abadir, A Mekkawy, H M McGuire, BFS Groth, I Cunningham, E Newman, J Gibson, PM Hogarth, DNJ Hart, GJ Clark
    J. Leukoc. Biol., 2019-11-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3)
    Authors: F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli
    Int J Mol Sci, 2019-10-24;20(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths
    Authors: NM Belle, Y Ji, K Herbine, Y Wei, J Park, K Zullo, LY Hung, S Srivatsa, T Young, T Oniskey, C Pastore, W Nieves, M Somsouk, DR Herbert
    Nat Commun, 2019-09-27;10(1):4408.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas
    Authors: L Chen, J Ouyang, K Wienand, K Bojarczuk, Y Hao, B Chapuy, D Neuberg, P Juszczynsk, LN Lawton, SJ Rodig, S Monti, MA Shipp
    Haematologica, 2019-08-30;105(5):1361-1368.
    Species: Human
    Sample Types:
    Applications: Functional Assay
  36. TCF12 promotes the tumorigenesis and metastasis of hepatocellular carcinoma via upregulation of CXCR4 expression
    Authors: J Yang, L Zhang, Z Jiang, C Ge, F Zhao, J Jiang, H Tian, T Chen, H Xie, Y Cui, M Yao, H Li, J Li
    Theranostics, 2019-08-12;9(20):5810-5827.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells
    Authors: C Ieranò, C D'Alterio, S Giarra, M Napolitano, G Rea, L Portella, A Santagata, AM Trotta, A Barbieri, V Campani, A Luciano, C Arra, AM Anniciello, G Botti, L Mayol, G De Rosa, R Pacelli, S Scala
    Cell Death Dis, 2019-07-22;10(8):562.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: In Vivo, Migration
  38. Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment
    Authors: DJ Wessels, N Pradhan, YN Park, MA Klepitsch, DF Lusche, KJ Daniels, KD Conway, ER Voss, SV Hegde, TP Conway, DR Soll
    PLoS ONE, 2019-06-24;14(6):e0218854.
    Species: Human
    Sample Types: Recombinant Protein, Whole Cells
    Applications: Bioassay, Cell Culture, Positive Control
  39. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling
    Authors: ML Capitano, N Mor-Vaknin, AK Saha, S Cooper, M Legendre, H Guo, R Contreras-, F Kappes, MA Sartor, CT Lee, X Huang, DM Markovitz, HE Broxmeyer
    J. Clin. Invest., 2019-05-20;130(0):2555-2570.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. RhoGDI2 positively regulates the Rho GTPases activation in response to the ?2 outside-in signaling in T cells adhesion and migration on ICAM-1
    Authors: W Liu, X Wang, S Wang, X Ba, T Xu, X Wang, X Zeng
    J. Leukoc. Biol., 2019-05-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer
    Authors: S Li, KW Fong, G Gritsina, A Zhang, JC Zhao, J Kim, A Sharp, W Yuan, C Aversa, XJ Yang, PS Nelson, FY Feng, AM Chinnaiyan, JS de Bono, C Morrissey, MB Rettig, J Yu
    Cancer Res., 2019-04-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates
    Authors: MJ Costa, J Kudaravall, JT Ma, WH Ho, K Delaria, C Holz, A Stauffer, AG Chunyk, Q Zong, E Blasi, B Buetow, TT Tran, K Lindquist, M Dorywalska, A Rajpal, DL Shelton, P Strop, SH Liu
    Sci Rep, 2019-02-21;9(1):2443.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo
    Authors: LF Pavon, TT Sibov, AV de Souza, EF da Cruz, SMF Malheiros, FR Cabral, JG de Souza, P Boufleur, DM de Oliveir, SRC de Toledo, LC Marti, JM Malheiros, FF Paiva, A Tannús, SM de Oliveir, AM Chudzinski, MA de Paiva N, S Cavalheiro
    Stem Cell Res Ther, 2018-11-09;9(1):310.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma
    Authors: S Mamand, RL Allchin, MJ Ahearne, SD Wagner
    Sci Rep, 2018-09-21;8(1):14216.
    Species: Human
    Sample Types: Whole Cells
  45. Senescent fibroblasts drive ageing pigmentation: ?A potential therapeutic target for senile lentigo
    Authors: JE Yoon, Y Kim, S Kwon, M Kim, YH Kim, JH Kim, TJ Park, HY Kang
    Theranostics, 2018-09-09;8(17):4620-4632.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. A feed-forward loop between nuclear translocation of CXCR4 and HIF-1? promotes renal cell carcinoma metastasis
    Authors: Y Bao, Z Wang, B Liu, X Lu, Y Xiong, J Shi, P Li, J Chen, Z Zhang, M Chen, L Wang, Z Wu
    Oncogene, 2018-09-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Simple Physical Model Unravels Influences of Chemokine on Shape Deformation and Migration of Human Hematopoietic Stem Cells
    Authors: T Ohta, C Monzel, AS Becker, AD Ho, M Tanaka
    Sci Rep, 2018-07-13;8(1):10630.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells
    Authors: W He, T Yang, XH Gong, RZ Qin, XD Zhang, WD Liu
    Oncol Lett, 2018-07-04;16(3):3976-3982.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Biomimetic post-capillary venule expansions for leukocyte adhesion studies
    Authors: BL Benson, L Li, JT Myers, RD Dorand, UA Gurkan, AY Huang, RM Ransohoff
    Sci Rep, 2018-06-19;8(1):9328.
  50. Phosphorylation of the ?-chain in the integrin LFA-1 enables ?2-chain phosphorylation and ?-actinin binding required for cell adhesion
    Authors: F Jahan, S Madhavan, T Rolova, L Viazmina, M Grönholm, CG Gahmberg
    J. Biol. Chem., 2018-06-14;0(0):.
    Applications: Bioassay
  51. Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis
    Authors: Y Nam, SM Jung, YA Rim, H Jung, K Lee, N Park, J Kim, Y Jang, YB Park, SH Park, JH Ju
    PLoS ONE, 2018-06-07;13(6):e0198740.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2)
    Authors: KM Dvorak, KM Pettee, K Rubinic-Mi, R Su, A Nestor-Kal, KM Eisenmann
    PLoS ONE, 2018-03-29;13(3):e0195278.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Transmission of integrin ?7 transmembrane domain topology enables gut lymphoid tissue development
    Authors: H Sun, F Lagarrigue, AR Gingras, Z Fan, K Ley, MH Ginsberg
    J. Cell Biol., 2018-03-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Engineering of thermoresponsive gels as a fake metastatic niche
    Authors: S Giarra, C Ierano, M Biondi, M Napolitano, V Campani, R Pacelli, S Scala, G De Rosa, L Mayol
    Carbohydr Polym, 2018-03-10;191(0):112-118.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Stromal-derived factor 1 directly promotes genes expressed within the ovulatory cascade in feline cumulus oocyte complexes
    Authors: JL Rojo, M Linari, KA Young, MC Peluffo
    J. Assist. Reprod. Genet., 2018-03-08;0(0):.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  56. CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation
    Authors: S Patalano, J Rodríguez-, C Colaneri, J Cotellessa, D Almanza, A Zhilin-Rot, T Riley, J Macoska
    Sci Rep, 2018-02-22;8(1):3499.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy
    Authors: TI Moore, J Aaron, TL Chew, TA Springer
    Cell Rep, 2018-02-13;22(7):1903-1912.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma
    Authors: W Tang, SG Smith, W Du, A Gugilla, J Du, JP Oliveria, K Howie, BM Salter, GM Gauvreau, PM O'Byrne, R Sehmi
    Clin Transl Allergy, 2018-02-13;8(0):5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria
    Authors: E Vågesjö, E Öhnstedt, A Mortier, H Lofton, F Huss, P Proost, S Roos, M Phillipson
    Proc. Natl. Acad. Sci. U.S.A., 2018-02-05;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  60. Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells
    Authors: SYN Jamaludin, I Azimi, FM Davis, AA Peters, TJ Gonda, EW Thompson, SJ Roberts-Th, GR Monteith
    Oncol Lett, 2018-01-19;15(4):4289-4295.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
    Authors: JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark
    Stem Cell Res, 2018-01-04;27(0):46-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Human Naive and Memory T Cells Display Opposite Migratory Responses to Sphingosine-1 Phosphate
    Authors: A Drouillard, A Neyra, AL Mathieu, A Marçais, M Wencker, J Marvel, A Belot, T Walzer
    J. Immunol., 2017-12-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
    Authors: W Oliva-Oliv, I Moreno-Ind, L Coín-Aragü, S Lhamyani, J Alcaide To, S Fernández-, J Vendrell, A Camargo, R El Bekay, FJ Tinahones
    PLoS ONE, 2017-11-22;12(11):e0188324.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia
    Authors: H Plešingero, P Janovská, A Mishra, L Smy?ková, L Poppová, A Libra, K Plevová, P Ovesná, L Radová, M Doubek, Š Pavlová, Š Pospíšilov, V Bryja
    Haematologica, 2017-11-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Protein profiling identified key chemokines that regulate the maintenance of human pluripotent stem cells
    Authors: Z Jiang, Y Li, X Ji, Y Tang, H Yu, L Ding, M Yu, Q Cui, M Zhang, Y Ma, M Li
    Sci Rep, 2017-11-06;7(1):14510.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Directional migration of mesenchymal stem cells under an SDF-1? gradient on a microfluidic device
    Authors: S Park, H Jang, BS Kim, C Hwang, GS Jeong, Y Park
    PLoS ONE, 2017-09-08;12(9):e0184595.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Regulation of CCR7-dependent cell migration through�CCR7 homodimer formation
    Authors: D Kobayashi, M Endo, H Ochi, H Hojo, M Miyasaka, H Hayasaka
    Sci Rep, 2017-08-17;7(1):8536.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Endothelial progenitor cell dysfunction in acute exacerbation of chronic obstructive pulmonary disease
    Authors: X Liu, Y Liu, X Huang, G Lin, C Xie
    Mol Med Rep, 2017-08-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells
    Authors: M Zhang, L Qiu, Y Zhang, D Xu, JC Zheng, L Jiang
    Sci Rep, 2017-08-15;7(1):8289.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Mechanisms of CXCR7 induction in malignant melanoma development
    Authors: XJ Li, P Liu, WW Tian, ZF Li, BG Liu, JF Sun
    Oncol Lett, 2017-08-04;14(4):4106-4114.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Frontline Science: CXCR7 mediates CD14(+)CD16(+) monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS
    Authors: M Veenstra, DW Williams, TM Calderon, K Anastos, S Morgello, JW Berman
    J. Leukoc. Biol., 2017-07-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate
    Authors: PJ Stewart-Hu, TP Szasz, ER Jaeger, MD Onken, JA Cooper, SC Morley
    J. Leukoc. Biol., 2017-06-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B-cells from apoptosis, enhance their migration and induce gene expression modifications
    Authors: E Crompot, M Van Damme, K Pieters, M Vermeersch, D Perez-Morg, P Mineur, M Maerevoet, N Meuleman, D Bron, L Lagneaux, B Stamatopou
    Haematologica, 2017-06-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells
    Authors: JH Kim, JW Shim, DY Eum, SD Kim, SH Choi, K Yang, K Heo, MT Park
    Sci Rep, 2017-06-05;7(1):2798.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor
    Authors: R Desplantes, C Lévêque, B Muller, M Lotierzo, G Ferracci, M Popoff, M Seagar, R Mamoun, O El Far
    Sci Rep, 2017-04-21;7(1):1032.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  76. Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
    Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
    PLoS ONE, 2017-04-18;12(4):e0176110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies
    Authors: DI Bromage, S Taferner, M Pillai, DM Yellon, SM Davidson
    PLoS ONE, 2017-04-05;12(4):e0174447.
    Species: Human
    Sample Types: Antibody, Plasma
    Applications: ELISA (Standard), Enzyme Assay
  78. Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma
    Authors: J Xu, J Liang, YM Meng, J Yan, XJ Yu, CQ Liu, L Xu, SM Zhuang, L Zheng
    Clin. Cancer Res, 2017-02-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Directional delivery of RSPO1 by mesenchymal stem cells ameliorates radiation-induced intestinal injury
    Authors: W Chen, S Ju, T Lu, Y Xu, X Zheng, H Wang, Y Ge, S Ju
    Cytokine, 2017-02-20;95(0):27-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. PLC?1 regulates SDF-1?-induced lymphocyte adhesion and migration to sites of inflammation
    Authors: M Strazza, I Azoulay-Al, M Peled, AV Smrcka, EY Skolnik, S Srivastava, A Mor
    Proc. Natl. Acad. Sci. U.S.A, 2017-02-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Hepatitis B virus X protein promotes the stem-like properties of OV6(+) cancer cells in hepatocellular carcinoma
    Authors: C Wang, MD Wang, P Cheng, H Huang, W Dong, WW Zhang, PP Li, C Lin, ZY Pan, MC Wu, WP Zhou
    Cell Death Dis, 2017-01-19;8(1):e2560.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Designed cell consortia as fragrance-programmable analog-to-digital converters
    Authors: M Müller, S Ausländer, A Spinnler, D Ausländer, J Sikorski, M Folcher, M Fussenegge
    Nat. Chem. Biol, 2017-01-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells
    Authors: M Moslem, R Eggenschwi, C Wichmann, R Buhmann, T Cantz, R Henschler
    Stem Cells Int, 2017-01-09;2017(0):7316354.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. MicroRNA expression profiles and networks in CXCL12?stimulated human endometrial stromal cells
    Mol Med Rep, 2016-12-07;15(1):249-255.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta
    Authors: Amber N Stratman
    Development, 2016-12-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library
    Authors: Renren Bai
    Eur J Med Chem, 2016-11-24;126(0):464-475.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia
    Sci Rep, 2016-10-07;6(0):34416.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Glioma Cell Invasion is Significantly Enhanced in Composite Hydrogel Matrices Composed of Chondroitin 4- and 4,6-Sulfated Glycosaminoglycans
    Authors: MT Logun, NS Bisel, EA Tanasse, W Zhao, B Gunasekera, L Mao, L Karumbaiah
    J Mater Chem B Mater Biol Med, 2016-08-26;4(36):6052-6064.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Local CXCR4 Up-regulation in Injured Arterial Wall Contributes to Intimal Hyperplasia
    Authors: Xudong Shi
    Stem Cells, 2016-07-17;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  90. HEREGULIN/ErbB3 SIGNALING ENHANCES CXCR4-DRIVEN Rac1 ACTIVATION AND BREAST CANCER CELL MOTILITY VIA HIF-1?
    Mol Cell Biol, 2016-07-14;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation
    Authors: Patricia Freund
    PLoS ONE, 2016-06-01;11(6):e0156693.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: Evidence for Partial Allosteric Agonism in Comparison to CXCL12
    J Biol Chem, 2016-05-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis
    Authors: S Velasquez, S Malik, SE Lutz, E Scemes, EA Eugenin
    J Immunol, 2016-04-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia.
    Authors: Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, Pospisilova S, Pavlova S, Bryja V
    Clin Cancer Res, 2015-08-03;22(2):459-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
    Authors: Heinzmann D, Bangert A, Muller A, von Ungern-Sternberg S, Emschermann F, Schonberger T, Chatterjee M, Mack A, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer H, Katus H, Fischer G, May A, Kaya Z, Seizer P
    PLoS ONE, 2015-04-20;10(4):e0124606.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
    Authors: Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J
    Nat Med, 2015-04-20;21(5):530-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Bortezomib inhibits expression of TGF-beta1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.
    Authors: Chang T, Poltoratsky V, Vancurova I
    J Immunol, 2015-02-13;194(6):2942-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Oligodendroglial maturation is dependent on intracellular protein shuttling.
    Authors: Gottle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, Parras C, Kremer D, Hartung H, Cate H, Kury P
    J Neurosci, 2015-01-21;35(3):906-19.
    Species: Human, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Protein z exerts pro-angiogenic effects and upregulates CXCR4.
    Authors: Butschkau, Antje, Wagner, Nana-Mar, Genz, Berit, Vollmar, Brigitte
    PLoS ONE, 2014-12-04;9(12):e113554.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals.
    Authors: Williams D, Anastos K, Morgello S, Berman J
    J Leukoc Biol, 2014-11-24;97(2):401-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Carbon monoxide down-regulates alpha4beta1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.
    Authors: Chigaev A, Smagley Y, Sklar L
    BMC Immunol, 2014-10-31;15(0):52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I.
    Authors: Watson H, Holley R, Langford-Smith K, Wilkinson F, van Kuppevelt T, Wynn R, Wraith J, Merry C, Bigger B
    J Biol Chem, 2014-10-30;289(52):36194-203.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. SDF-1alpha is a novel autocrine activator of platelets operating through its receptor CXCR4.
    Authors: Walsh T, Harper M, Poole A
    Cell Signal, 2014-10-05;27(1):37-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors.
    Authors: Mendes-Da-Cruz D, Brignier A, Asnafi V, Baleydier F, Messias C, Lepelletier Y, Bedjaoui N, Renand A, Smaniotto S, Canioni D, Milpied P, Balabanian K, Bousso P, Lepretre S, Bertrand Y, Dombret H, Ifrah N, Dardenne M, Macintyre E, Savino W, Hermine O
    PLoS ONE, 2014-07-28;9(7):e103405.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. CXCL12-gamma in primary tumors drives breast cancer metastasis.
    Authors: Ray P, Stacer A, Fenner J, Cavnar S, Meguiar K, Brown M, Luker K, Luker G
    Oncogene, 2014-06-09;34(16):2043-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration.
    Authors: Boudot A, Kerdivel G, Lecomte S, Flouriot G, Desille M, Godey F, Leveque J, Tas P, Le Drean Y, Pakdel F
    BMC Cancer, 2014-06-06;14(0):407.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. CXCR7 controls competition for recruitment of beta-arrestin 2 in cells expressing both CXCR4 and CXCR7.
    Authors: Coggins N, Trakimas D, Chang S, Ehrlich A, Ray P, Luker K, Linderman J, Luker G
    PLoS ONE, 2014-06-04;9(6):e98328.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.
    Authors: Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit M, Blanchet X, von Hundelshausen P, Weber C, Forssmann W, Henschler R
    Stem Cells Dev, 2014-05-27;23(16):1959-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.
    Authors: Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A
    J Biol Chem, 2014-04-16;289(22):15340-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma.
    Authors: Krook M, Nicholls L, Scannell C, Chugh R, Thomas D, Lawlor E
    Mol Cancer Res, 2014-03-20;12(6):953-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. SDF-1/CXCR4 signaling preserves microvascular integrity and renal function in chronic kidney disease.
    Authors: Chen L, Advani S, Thai K, Kabir M, Sood M, Gibson I, Yuen D, Connelly K, Marsden P, Kelly D, Gilbert R, Advani A
    PLoS ONE, 2014-03-17;9(3):e92227.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
    Authors: Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K
    J Immunol, 2014-02-28;192(7):3390-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia.
    Authors: Zucco L, Zhang Q, Kuliszewski M, Kandic I, Faughnan M, Stewart D, Kutryk M
    PLoS ONE, 2014-02-25;9(2):e89927.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways.
    Authors: Lo H, Lai T, Li C, Wu W
    Acta Pharmacol Sin, 2014-02-03;35(3):339-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Complex cellular composition of solitary fibrous tumor of the prostate.
    Authors: Gharaee-Kermani M, Mehra R, Robinson D, Wei J, Macoska J
    Am J Pathol, 2014-01-13;184(3):732-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
    Authors: Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter P, Schakel K, Tamassia N, Cassatella M
    Nat Commun, 2014-01-01;5(0):3029.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. A paracrine network regulates the cross-talk between human lung stem cells and the stroma.
    Authors: Ruiz E, Oeztuerk-Winder F, Ventura J
    Nat Commun, 2014-01-01;5(0):3175.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013-12-31;8(12):e85147.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
    Authors: Hoellenriegel J, Zboralski D, Maasch C, Rosin N, Wierda W, Keating M, Kruschinski A, Burger J
    Blood, 2013-11-25;123(7):1032-9.
    Applications: Bioassay
  120. PCaAnalyser: a 2D-image analysis based module for effective determination of prostate cancer progression in 3D culture.
    Authors: Hoque, Md Tamji, Windus, Louisa C, Lovitt, Carrie J, Avery, Vicky M
    PLoS ONE, 2013-11-20;8(11):e79865.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  121. Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro.
    Authors: Wen W, Xie S, Xin X, Geng M, Ding J, Chen Y
    Acta Pharmacol Sin, 2013-10-21;34(12):1554-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  122. Impaired endothelial progenitor cell mobilization and dysfunctional bone marrow stroma in diabetes mellitus.
    Authors: Westerweel, Peter E, Teraa, Martin, Rafii, Shahin, Jaspers, Janneke, White, Ian A, Hooper, Andrea T, Doevendans, Pieter A, Verhaar, Marianne
    PLoS ONE, 2013-03-28;8(3):e60357.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses.
    Authors: Cheng, Cheng-Ch, Chang, Shing-Jy, Chueh, Yu-Neng, Huang, Tse-Shun, Huang, Po-Hsun, Cheng, Shu-Meng, Tsai, Tsung-Ne, Chen, Jaw-Wen, Wang, Hsei-Wei
    BMC Genomics, 2013-03-15;14(0):182.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation.
    Authors: Akimoto, Keiko, Kimura, Kenichi, Nagano, Masumi, Takano, Shingo, To'a Salazar, Georgina, Yamashita, Toshihar, Ohneda, Osamu
    Stem Cells Dev, 2013-02-04;22(9):1370-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration.
    Authors: Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C
    Blood, 2012-10-16;121(2):403-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia.
    BMC Cancer, 2012-09-26;12(0):431.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
    Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
    Nature, 2012-07-26;487(7408):505-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.
    Authors: Tai Y, Chang B, Kong S, Fulciniti M, Yang G, Calle Y, Hu Y, Lin J, Zhao J, Cagnetta A, Cea M, Sellitto M, Zhong M, Wang Q, Acharya C, Carrasco D, Buggy J, Elias L, Treon S, Matsui W, Richardson P, Munshi N, Anderson K
    Blood, 2012-06-11;120(9):1877-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
    Authors: Badr G, Lefevre EA, Mohany M
    PLoS ONE, 2011-09-01;6(9):e23741.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Structural basis of digoxin that antagonizes RORgamma t receptor activity and suppresses Th17 cell differentiation and interleukin (IL)-17 production.
    Authors: Fujita-Sato S, Ito S, Isobe T, Ohyama T, Wakabayashi K, Morishita K, Ando O, Isono F
    J. Biol. Chem., 2011-07-06;286(36):31409-17.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  131. Stromal cell-derived factor-1 enhances distraction osteogenesis-mediated skeletal tissue regeneration through the recruitment of endothelial precursors.
    Authors: Fujio M, Yamamoto A, Ando Y, Shohara R, Kinoshita K, Kaneko T, Hibi H, Ueda M
    Bone, 2011-06-29;49(4):693-700.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  132. The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.
    Authors: Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S
    Clin. Cancer Res., 2011-04-11;17(11):3619-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1alpha/CXCL12 in the brain.
    Authors: Benamar K, Palma J, Cowan A, Geller EB, Adler MW
    Drug Alcohol Depend, 2010-11-26;114(2):246-8.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  134. Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture.
    Authors: Burton VJ, Butler LM, McGettrick HM, Stone PC, Jeffery HC, Savage CO, Rainger GE, Nash GB
    Exp. Cell Res., 2010-11-04;317(3):276-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. CXCR7 protein is not expressed on human or mouse leukocytes.
    Authors: Berahovich RD, Zabel BA, Penfold ME, Lewen S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ
    J. Immunol., 2010-10-01;185(9):5130-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Binding Assay
  136. Implication of discoidin domain receptor 1 in T cell migration in three-dimensional collagen.
    Authors: Hachehouche LN, Chetoui N, Aoudjit F
    Mol. Immunol., 2010-03-29;47(9):1866-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Characterization of circulating dendritic cells in melanoma: role of CCR6 in plasmacytoid dendritic cell recruitment to the tumor.
    Authors: Charles J, Di Domizio J, Salameire D, Bendriss-Vermare N, Aspord C, Muhammad R, Lefebvre C, Plumas J, Leccia MT, Chaperot L
    J. Invest. Dermatol., 2010-03-11;130(6):1646-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization.
    Authors: Sengupta N, Afzal A, Caballero S, Chang KH, Shaw LC, Pang JJ, Bond VC, Bhutto I, Baba T, Lutty GA, Grant MB
    Invest. Ophthalmol. Vis. Sci., 2009-12-10;51(5):2697-704.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation.
    Authors: Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE
    Blood, 2009-10-12;114(24):5091-101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.
    Authors: Kenig S, Alonso MB, Mueller MM, Lah TT
    Cancer Lett., 2009-08-22;289(1):53-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy.
    Authors: Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C
    FASEB J., 2009-04-20;23(9):2928-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.
    Authors: Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R
    J. Exp. Med., 2009-03-09;206(3):535-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin.
    Authors: Skrzeczynska-Moncznik J, Wawro K, Stefanska A, Oleszycka E, Kulig P, Zabel BA, Sulkowski M, Kapinska-Mrowiecka M, Czubak-Macugowska M, Butcher EC, Cichy J
    Biochem. Biophys. Res. Commun., 2009-01-23;380(2):323-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment.
    Authors: Crawford Y, Kasman I, Yu L, Zhong C, Wu X, Modrusan Z, Kaminker J, Ferrara N
    Cancer Cell, 2009-01-06;15(1):21-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  145. Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4.
    Authors: Struyf S, Noppen S, Loos T, Mortier A, Gouwy M, Verbeke H, Huskens D, Luangsay S, Parmentier M, Geboes K, Schols D, Van Damme J, Proost P
    J. Immunol., 2009-01-01;182(1):666-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
    Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
    J. Immunol., 2008-12-01;181(11):8053-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis.
    Authors: Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S
    Eur. J. Immunol., 2008-11-01;38(11):3050-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo.
    Authors: Kerfoot SM, Andonegui G, Bonder CS, Liu L
    Am. J. Physiol. Heart Circ. Physiol., 2008-04-18;294(6):H2524-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  149. Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
    Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
    Nature, 2007-12-06;450(7171):825-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells.
    Authors: Kaminski A, Ma N, Donndorf P, Lindenblatt N, Feldmeier G, Ong LL, Furlani D, Skrabal CA, Liebold A, Vollmar B, Steinhoff G
    Lab. Invest., 2007-11-26;88(1):58-69.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  151. Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain.
    Authors: Isakova IA, Baker K, Dutreil M, Dufour J, Gaupp D, Phinney DG
    Stem Cells, 2007-10-11;25(12):3261-70.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  152. iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.
    Authors: Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT
    J. Immunol., 2007-10-01;179(7):4661-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.
    Authors: Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M
    J. Clin. Invest., 2007-09-01;117(9):2526-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
    Authors: Bayry J, Triebel F, Kaveri SV, Tough DF
    J. Immunol., 2007-04-01;178(7):4184-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
    Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
    Glia, 2006-11-01;54(6):619-29.
    Applications: ELISA (Standard)
  156. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.
    Authors: Nakayama T, Mutsuga N, Tosato G
    Blood, 2006-10-31;109(4):1363-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
    Authors: Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R
    Blood, 2006-10-12;109(4):1381-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3.
    Authors: Saunders WB, Bohnsack BL, Faske JB, Anthis NJ, Bayless KJ, Hirschi KK, Davis GE
    J. Cell Biol., 2006-10-09;175(1):179-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54.
    Authors: Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan AI, Facchini A
    J. Cell. Physiol., 2006-05-01;207(2):364-73.
    Applications: ELISA (Standard)
  160. Novel antiviral activity of chemokines.
    Authors: Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, Nagakubo D, Saito T, Shimomura Y, Yoshie O
    Virology, 2006-04-17;350(2):484-92.
    Species: Virus
    Sample Types: Virus, Whole Cells
    Applications: Binding Assay, Bioassay
  161. Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells.
    Authors: Infantino S, Moepps B, Thelen M
    J. Immunol., 2006-02-15;176(4):2197-207.
    Applications: ELISA (Standard)
  162. Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles.
    Authors: Anghelina M, Krishnan P, Moldovan L, Moldovan NI
    Am. J. Pathol., 2006-02-01;168(2):529-41.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  163. Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
    Authors: Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG
    Cardiovasc. Res., 2006-01-10;69(4):925-35.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  164. Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells.
    Authors: Corti S, Locatelli F, Papadimitriou D, Donadoni C, Del Bo R, Fortunato F, Strazzer S, Salani S, Bresolin N, Comi GP
    FASEB J., 2005-09-08;19(13):1860-2.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  165. Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.
    Authors: Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B
    Arthritis Rheum., 2005-05-01;52(5):1504-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.
    Authors: Curiel, Tyler J, Coukos, George, Zou, Linhua, Alvarez, Xavier, Cheng, Pui, Mottram, Peter, Evdemon-Hogan, Melina, Conejo-Garcia, Jose R, Zhang, Lin, Burow, Matthew, Zhu, Yun, Wei, Shuang, Kryczek, Ilona, Daniel, Ben, Gordon, Alan, Myers, Leann, Lackner, Andrew, Disis, Mary L, Knutson, Keith L, Chen, Lieping, Zou, Weiping
    Nat Med, 2004-08-22;10(9):942-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Characterization of hematopoietic progenitor mobilization in protease-deficient mice.
    Authors: Levesque JP, Liu F, Simmons PJ, Betsuyaku T, Senior RM, Pham C, Link DC
    Blood, 2004-03-09;104(1):65-72.
    Applications: ELISA (Standard)
  168. HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis.
    Authors: Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J
    PLoS Biol., 2004-01-20;2(1):E6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Development of a novel surrogate virus for human T-cell leukemia virus type 1: inhibition of infection by osteoprotegerin.
    Authors: Okuma K, Dalton KP, Buonocore L, Ramsburg E, Rose JK
    J. Virol., 2003-08-01;77(15):8562-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo.
    Authors: Villalba S, Salvucci O, Aoki Y, De La Luz Sierra M, Gupta G, Davis D, Wyvill K, Little R, Yarchoan R, Tosato G
    J. Leukoc. Biol., 2003-07-22;74(5):880-8.
    Species: Human, Mouse
    Sample Types: N/A, Whole Cells
    Applications: Bioassay, Control, ELISA (Standard), Western Blot
  171. Expression of functional CCR and CXCR chemokine receptors in podocytes.
    Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
    J. Immunol., 2002-06-15;168(12):6244-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
    Authors: Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S
    Cell, 2002-05-31;109(5):625-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes.
    Authors: Zamarchi R, 2019, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, Esposito G, Roni V, Paganin C, Bianchi G, Titti F, Verani P, Gerosa G, Amadori A
    192, 2002-02-01;127(2):321-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. A CD4-independent interaction of human immunodeficiency virus-1 gp120 with CXCR4 induces their cointernalization, cell signaling, and T-cell chemotaxis.
    Authors: Misse D, Cerutti M, Noraz N, Jourdan P, Favero J, Devauchelle G, Yssel H, Taylor N, Veas F
    Blood, 1999-04-15;93(8):2454-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Does Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) contain any tags?

    • Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) does not contain any tags. Please refer to the Source section on the product-specific page for sequence information.

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Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
By Anonymous on 01/13/2020
Application: In vitro bioactivity in cell culture
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
By Anonymous on 05/27/2019
Application: In vitro bioactivity in cell culture
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
By Anonymous on 03/13/2019
Application: Receptor activation by CXCL12 Ligand to screen for NFKB pathway activation by Western Blot: Treat MDA231 cells with CXCL12 to look into whether CXCR4 activation by CXCL12 induced NFkB activation by phosphorylating IkBa by Western Blot
Reason for Rating: Receptor activation by CXCL12 Ligand to screen for NFKB pathway activation by Western Blot: Treat MDA231 cells with CXCL12 to look into whether CXCR4 activation by CXCL12 induced NFkB activation by phosphorylating IkBa by Western Blot
Other Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha 350-NS
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
By Anonymous on 08/09/2016
Application: Cell migration/motility
Cell migration/motility Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha 350-NS