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Recombinant Mouse M-CSF Protein

Catalog #: 416-ML
606 Citations 18 Reviews Datasheet / COA / SDS
Analyzed by SEC-MALS

Carrier Free

Catalog # Availability Size / Price Qty
416-ML-010/CF
416-ML-050/CF

With Carrier

Catalog # Availability Size / Price Qty
416-ML-010
416-ML-050
416-ML-500
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Recombinant Mouse M‑CSF Protein SEC-MALS.
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Product Details
Citations (606)
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Supplemental Products
Reviews (18)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse M-CSF Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<1.0 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. Nakoinz, I. et al. (1990) J. Immunol. 145:860. The ED50 for this effect is 0.5‑3 ng/mL.
Source
E. coli-derived mouse M-CSF protein
Lys33-Glu262, with an N-terminal Met
Accession #
Q3U4F9
N-terminal Sequence
Analysis
Met
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
26 kDa (monomer)
SDS-PAGE
29 kDa, reducing conditions

Product Datasheets

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416-ML (with carrier)

Product Datasheet
COA
SDS

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416-ML/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

416-ML

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

416-ML/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

SEC-MALS View Larger

Recombinant Mouse M-CSF Protein (Catalog # 416-ML) has a molecular weight (MW) of 50.7 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer.

Bioactivity Graph showing dose-dependent bioactivity of Human M-CSF Protein View Larger

Recombinant Mouse M-CSF (416-ML) stimulates cell proliferation in the M-NFS-60 mouse myelogenous leukemia lymphoblast cell line in a dose-dependent manner. The ED50 for this effect is 0.5-3 ng/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: M-CSF

M-CSF, also known as CSF-1, is a four-alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation (1-3). M-CSF protein is also essential for the survival and proliferation of osteoclast progenitors (1, 4). M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis (2, 3). M-CSF increases during pregnancy to support implantation and growth of the decidua and placenta (5). Sources of M-CSF include fibroblasts, activated macrophages, endometrial secretory epithelium, bone marrow stromal cells and activated endothelial cells (1-5). The M-CSF receptor (c-fms) transduces its pleotropic effects and mediates its endocytosis. M-CSF mRNAs of various sizes occur (3-9). Full length mouse M-CSF transcripts encode a 520 amino acid (aa) type I transmembrane (TM) protein with a 462 aa extracellular region, a 21 aa TM domain, and a 37 aa cytoplasmic tail that forms a 140 kDa covalent dimer. Differential processing produces two proteolytically cleaved, secreted dimers. One is an N- and O- glycosylated 86 kDa dimer, while the other is modified by both glycosylation and chondroitin-sulfate proteoglycan (PG) to generate a 200 kDa subunit. Although PG-modified M-CSF protein can circulate, it may be immobilized by attachment to type V collagen (8). Shorter transcripts encode M‑CSF that lacks cleavage and PG sites and produces an N-glycosylated 68 kDa TM dimer and a slowly produced 44 kDa secreted dimer (7). Although forms may vary in activity and half-life, all contain the N-terminal 150 aa portion that is necessary and sufficient for interaction with the M-CSF receptor (10, 11). The first 229 aa of mature mouse M-CSF shares 87%, 83%, 82% and 81% aa identity with corresponding regions of rat, dog, cow and human M-CSF, respectively (12, 13). Human M‑CSF is active in the mouse, but mouse M-CSF is reported to be species-specific.

References
  1. Pixley, F.J. and E.R. Stanley (2004) Trends Cell Biol. 14:628.
  2. Chitu, V. and E.R. Stanley (2006) Curr. Opin. Immunol. 18:39.
  3. Fixe, P. and V. Praloran (1997) Eur. Cytokine Netw. 8:125.
  4. Ryan, G.R. et al. (2001) Blood 98:74.
  5. Makrigiannakis, A. et al. (2006) Trends Endocrinol. Metab. 17:178.
  6. Nandi, S. et al. (2006) Blood 107:786.
  7. Rettenmier, C.W. and M.F. Roussel (1988) Mol. Cell Biol. 8:5026.
  8. Suzu, S. et al. (1992) J. Biol. Chem. 267:16812.
  9. Manos, M.M. (1988) Mol. Cell. Biol. 8:5035.
  10. Koths, K. (1997) Mol. Reprod. Dev. 46:31.
  11. Jang, M-H. et al. (2006) J. Immunol. 177:4055.
  12. DeLamarter, J.F. et al. (1987) Nucleic Acids Res. 15:2389.
  13. Ladner, M.B. et al. (1988) Proc. Natl. Acad. Sci. USA 85:6706.
Long Name
Macrophage Colony Stimulating Factor
Entrez Gene IDs
1435 (Human); 12977 (Mouse)
Alternate Names
colony stimulating factor 1 (macrophage); CSF1; CSF-1; Lanimostim; macrophage colony stimulating factor; macrophage colony-stimulating factor 1; MCSF; M-CSF; MCSFlanimostim; MGC31930

Citations for Recombinant Mouse M-CSF Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

606 Citations: Showing 1 - 10
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  1. Inhibitory effects of norcantharidin on titanium particle-induced osteolysis, osteoclast activation and bone resorption via MAPK pathways
    Authors: Wang, J;Chen, G;Yang, X;Dou, W;Mao, Y;Zhang, Y;Shi, X;Xia, Y;You, Q;Liu, M;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Planar catechin increases bone mass by regulating differentiation of osteoclasts in mice
    Authors: Sugawara, D;Sakai, N;Sato, Y;Azetsu, Y;Karakawa, A;Chatani, M;Mizuno, M;Maruoka, Y;Myers, M;Fukuhara, K;Takami, M;
    Journal of oral biosciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Transient receptor potential melastatin 2 is involved in trinitrobenzene sulfonic acid-induced acute and chronic colitis-associated fibrosis progression in mice
    Authors: Nakamoto, T;Matsumoto, K;Yasuda, H;Mori, Y;Kato, S;
    Journal of pharmacological sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Colon-targeted S100A8/A9-specific peptide systems ameliorate colitis and colitis-associated colorectal cancer in mouse models
    Authors: Cho, E;Mun, SJ;Kim, HK;Ham, YS;Gil, WJ;Yang, CS;
    Acta pharmacologica Sinica
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. IgSF11 deficiency alleviates osteoarthritis in mice by suppressing early subchondral bone changes
    Authors: Kim, GM;Kim, J;Lee, JY;Park, MC;Lee, SY;
    Experimental & molecular medicine
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. RANKL-dependent osteoclast differentiation and gene expression in bone marrow-derived cells from adult mice is sexually dimorphic
    Authors: Desai, S;Lång, P;Näreoja, T;Windahl, SH;Andersson, G;
    Bone reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Osteoclast-derived exosomal miR-212-3p suppressed the anabolism and accelerated the catabolism of chondrocytes in osteoarthritis by targeting TGF-?1/Smad2 signaling
    Authors: Dai, J;Hu, Z;Zeng, F;Gong, X;Tang, H;Deng, J;Li, J;Dong, S;
    Archives of biochemistry and biophysics
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Sesamin inhibits RANKL-induced osteoclastogenesis and attenuates LPS-induced osteolysis via suppression of ERK and NF-?B signalling pathways
    Authors: Yu, X;Hu, J;Yang, X;Xu, Q;Chen, H;Zhan, P;Zhang, B;
    Journal of cellular and molecular medicine
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Protective effects of macrophage-specific integrin ?5 in myocardial infarction are associated with accentuated angiogenesis
    Authors: Li, R;Chen, B;Kubota, A;Hanna, A;Humeres, C;Hernandez, SC;Liu, Y;Ma, R;Tuleta, I;Huang, S;Venugopal, H;Zhu, F;Su, K;Li, J;Zhang, J;Zheng, D;Frangogiannis, NG;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. A novel Glycyrrhiza glabra extract liquiritin targeting NFATc1 activity and ROS levels to counteract ovariectomy-induced osteoporosis and bone loss in murine model
    Authors: Hong, G;Zhou, L;Zheng, G;Zheng, X;Chen, Z;He, W;Wei, Q;
    Frontiers in pharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Britanin inhibits titanium wear particle?induced osteolysis and osteoclastogenesis
    Authors: Kim, JA;Lim, S;Ihn, HJ;Kim, JE;Yea, K;Moon, J;Choi, H;Park, EK;
    Molecular medicine reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Osteoprotective effect by interleukin-4 (IL-4) on lipoprotein-induced periodontitis
    Authors: Lima Teixeira, JF;Henning, P;Cintra Magalhães, FA;Coletto-Nunes, G;Floriano-Marcelino, T;Westerlund, A;Movérare-Skrtic, S;Oliveira, GJPL;Lerner, UH;Souza, PPC;
    Cytokine
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. AMPK?1 negatively regulates osteoclastogenesis and mitigate pathological bone loss
    Authors: Ribeiro, MSP;Venturini, LGR;Speck-Hernandez, CA;Alabarse, PVG;Xavier, T;Taira, TM;Rodrigues, LFD;Cunha, FQ;Fukada, SY;
    The Journal of biological chemistry
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model
    Authors: Wu, L;Yin, W;Wen, J;Wang, S;Li, H;Wang, X;Zhang, W;Duan, S;Zhu, Q;Gao, E;Wu, S;Zhan, B;Zhou, R;Yang, X;
    Parasites & vectors
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Ulmus macrocarpa Hance trunk bark extracts inhibit RANKL-induced osteoclast differentiation and prevent ovariectomy-induced osteoporosis in mice
    Authors: Jeong, C;Lee, CH;Lee, Y;Seo, J;Wang, W;Park, KH;Oh, E;Cho, Y;Park, C;Son, YJ;Yoon Park, JH;Kang, H;Lee, KW;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
    Authors: Adrian, M;Weber, M;Tsai, MC;Glock, C;Kahn, OI;Phu, L;Cheung, TK;Meilandt, WJ;Rose, CM;Hoogenraad, CC;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins
    Authors: Dissing-Olesen, L;Walker, AJ;Feng, Q;Barr, HJ;Walker, AC;Xie, L;Wilton, DK;Das, I;Benowitz, LI;Stevens, B;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. BAP1 promotes osteoclast function by metabolic reprogramming
    Authors: Rohatgi, N;Zou, W;Li, Y;Cho, K;Collins, PL;Tycksen, E;Pandey, G;DeSelm, CJ;Patti, GJ;Dey, A;Teitelbaum, SL;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. NLRP3 selectively drives IL-1? secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity
    Authors: Minns, MS;Liboro, K;Lima, TS;Abbondante, S;Miller, BA;Marshall, ME;Tran Chau, J;Roistacher, A;Rietsch, A;Dubyak, GR;Pearlman, E;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression
    Authors: Zhao, L;Song, R;Liu, Y;
    European journal of immunology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Echinococcus granulosus promotes bone resorption by increasing osteoclasts differentiation
    Authors: Sun, H;Wang, S;Tan, W;Li, Y;Ren, Q;Liu, Y;Huang, Y;Shi, C;Li, J;
    Acta tropica
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Interleukin-10 increases macrophage-mediated chemotherapy resistance via FABP5 signaling in multiple myeloma
    Authors: Zhang, M;Chen, J;Zhang, H;Dong, H;Yue, Y;Wang, S;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Impaired mitophagy induces antimicrobial responses in macrophages infected with Mycobacterium tuberculosis
    Authors: Lee, J;Lee, SA;Son, SH;Choi, JA;Nguyen, TD;Kim, J;Son, D;Song, CH;
    Cell & bioscience
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Conditional Loss of MEF2C Expression in Osteoclasts Leads to a Sex-Specific Osteopenic Phenotype
    Authors: Maisuria, R;Norton, A;Shao, C;Bradley, EW;Mansky, K;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  25. GV1001 Inhibits the Severity of the Ligature-Induced Periodontitis and the Vascular Lipid Deposition Associated with the Periodontitis in Mice
    Authors: Kim, SY;Kim, YJ;Kim, S;Momeni, M;Lee, A;Treanor, A;Kim, S;Kim, RH;Park, NH;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction
    Authors: Shimizu, K;Kikuta, J;Ohta, Y;Uchida, Y;Miyamoto, Y;Morimoto, A;Yari, S;Sato, T;Kamakura, T;Oshima, K;Imai, R;Liu, YC;Okuzaki, D;Hara, T;Motooka, D;Emoto, N;Inohara, H;Ishii, M;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  27. Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization
    Authors: Namangkalakul, W;Nagai, S;Jin, C;Nakahama, KI;Yoshimoto, Y;Ueha, S;Akiyoshi, K;Matsushima, K;Nakashima, T;Takechi, M;Iseki, S;
    Journal of tissue engineering
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice
    Authors: Yu, L;Xu, L;Chu, H;Peng, J;Sacharidou, A;Hsieh, HH;Weinstock, A;Khan, S;Ma, L;Durán, JGB;McDonald, J;Nelson, ER;Park, S;McDonnell, DP;Moore, KJ;Huang, LJ;Fisher, EA;Mineo, C;Huang, L;Shaul, PW;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
    Authors: Fu, J;Li, S;Ma, H;Yang, J;Pagnotti, GM;Brown, LM;Weiss, SJ;Mapara, MY;Lentzsch, S;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. MiR-662 is associated with metastatic relapse in early-stage breast cancer and promotes metastasis by stimulating cancer cell stemness
    Authors: Puppo, M;Valluru, MK;Croset, M;Ceresa, D;Iuliani, M;Khan, A;Wicinski, J;Charafe-Jauffret, E;Ginestier, C;Pantano, F;Ottewell, PD;Clézardin, P;
    British journal of cancer
    Applications: Cell Culture
  31. Discovery and optimized extraction of the anti-osteoclastic agent epicatechin-7-O-beta -D-apiofuranoside from Ulmus macrocarpa Hance bark
    Authors: Jeong, C;Cho, YJ;Lee, Y;Wang, W;Park, KH;Roh, E;Lee, CH;Son, YJ;Park, JHY;Kang, H;Lee, KW;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  32. Accelerated Bone Loss in Transgenic Mice Expressing Constitutively Active TGF-beta Receptor Type I
    Authors: Toejing, P;Sakunrangsit, N;Pho-On, P;Phetkong, C;Leelahavanichkul, A;Sridurongrit, S;Greenblatt, MB;Lotinun, S;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Polyphyllin VII protects from breast cancer-induced osteolysis by suppressing osteoclastogenesis via c-Fos/NFATc1 signaling
    Authors: Yang, Q;Guo, J;Zheng, J;Chen, Y;Zou, B;Li, R;Ding, Z;Wang, Y;Li, L;Chen, Z;Mo, L;Liang, Q;Chen, F;Li, X;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages
    Authors: Lu, Y;Zhang, H;Pan, H;Zhang, Z;Zeng, H;Xie, H;Yin, J;Tang, W;Lin, R;Zeng, C;Cai, D;
    Journal of translational medicine
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Predicting gene level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework
    Authors: Cheemalavagu, N;Shoger, KE;Cao, YM;Michalides, BA;Botta, SA;Faeder, JR;Gottschalk, RA;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Inhibition of NADPH Oxidase (NOX) 2 Mitigates Colitis in Mice with Impaired Macrophage AMPK Function
    Authors: Banskota, S;Wang, H;Kwon, YH;Gautam, J;Haq, S;Grondin, J;Steinberg, GR;Khan, WI;
    Biomedicines
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis
    Authors: Stavre, Z;Kim, JM;Yang, YS;N�ndel, K;Chaugule, S;Sato, T;Park, KH;Gao, G;Gravallese, EM;Shim, JH;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. IRAK4 inhibition: an effective strategy for immunomodulating peri-implant osseointegration via reciprocally-shifted polarization in the monocyte-macrophage lineage cells
    Authors: Zhao, J;Li, J;Xu, A;Xu, Y;He, F;Mao, Y;
    BMC oral health
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development
    Authors: Cheu, JW;Chiu, DK;Kwan, KK;Yang, C;Yuen, VW;Goh, CC;Chui, NN;Shen, W;Law, CT;Li, Q;Zhang, MS;Bao, MH;Wong, BP;Chan, CY;Liu, CX;Sit, GF;Ooi, ZY;Deng, H;Tse, AP;Ng, IO;Wong, CC;
    Science advances
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses
    Authors: Y Yu, M Wang, XW Li, J Mao, YJ Zhu, N Wang, LH Yin, ZL Guo, H Cai, T Li, TT Liang, J Cui, T Zhou
    Cell & bioscience, 2023-04-29;13(1):76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. The Anti-Atopic Dermatitis Effects of Mentha arvensis Essential Oil Are Involved in the Inhibition of the NLRP3 Inflammasome in DNCB-Challenged Atopic Dermatitis BALB/c Mice
    Authors: Kim, SY;Sapkota, A;Bae, YJ;Choi, SH;Bae, HJ;Kim, HJ;Cho, YE;Choi, YY;An, JY;Cho, SY;Hong, SH;Choi, JW;Park, SJ;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Distinct Responses to IL4 in Macrophages Mediated by JNK
    Authors: Arpa, L;Batlle, C;Jiang, P;Caelles, C;Lloberas, J;Celada, A;
    Cells
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice
    Authors: S MacLauchla, P Kushwaha, A Tai, J Chen, C Manning, G Swarnkar, Y Abu-Amer, KA Fitzgerald, S Sharma, EM Gravallese
    Proceedings of the National Academy of Sciences of the United States of America, 2023-04-06;120(15):e2210409120.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Matrix stiffness regulates osteoclast fate through integrin-dependent mechanotransduction
    Authors: X Wang, L Ji, J Wang, C Liu
    Bioactive materials, 2023-03-30;27(0):138-153.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Atf4 regulates angiogenic differences between alveolar bone and long bone macrophages by regulating M1 polarization, based on single-cell RNA sequencing, RNA-seq and ATAC-seq analysis
    Authors: L Gu, Z Wang, H Gu, H Wang, L Liu, WB Zhang
    Journal of Translational Medicine, 2023-03-14;21(1):193.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Itaconate ameliorates autoimmunity by modulating T cell imbalance via metabolic and epigenetic reprogramming
    Authors: K Aso, M Kono, M Kanda, Y Kudo, K Sakiyama, R Hisada, K Karino, Y Ueda, D Nakazawa, Y Fujieda, M Kato, O Amengual, T Atsumi
    Nature Communications, 2023-02-27;14(1):984.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux
    Authors: X Ji, J Hong, W Yang, M Yao, J Wang, G Jiang, Y Wang, C Li, J Lin, H Mou, C Li, S Li, Y Chen, M Shi, W Wang, F Lu, H Wu, X Zhao, Y Qi, S Yan
    Redox Biology, 2023-02-27;61(0):102635.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Cedrol, a Ginger-derived sesquiterpineol, suppresses estrogen-deficient osteoporosis by intervening NFATc1 and reactive oxygen species
    Authors: C Xu, SQ Jin, C Jin, ZH Dai, YH Wu, GL He, HW Ma, CY Xu, WL Fang
    International immunopharmacology, 2023-02-27;117(0):109893.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Sugar transporter Slc37a2 regulates bone metabolism in mice via a tubular lysosomal network in osteoclasts
    Authors: PY Ng, ABP Ribet, Q Guo, BH Mullin, JWY Tan, E Landao-Bas, S Stephens, K Chen, J Yuan, L Abudulai, M Bollen, ETTT Nguyen, J Kular, JM Papadimitr, K Søe, RD Teasdale, J Xu, RG Parton, H Takayanagi, NJ Pavlos
    Nature Communications, 2023-02-21;14(1):906.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. C3a-C3aR signaling is a novel modulator of skeletal homeostasis
    Authors: MB Kuhn, HS VandenBerg, AJ Reynolds, MD Carson, AJ Warner, AC LaRue, CM Novince, JD Hathaway-S
    Bone Reports, 2023-02-16;18(0):101662.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Obacunone inhibits RANKL/M-CSF-mediated osteoclastogenesis by suppressing integrin- FAK-Src signaling
    Authors: H Hu, X Wang, Y Huang, B He, J Zhu, K Sun, C Deng, Y Guo, D Hao, B Jian
    Cytokine, 2023-02-15;164(0):156134.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. miRNA-Induced Downregulation of IPMK in Macrophages Mediates Lipopolysaccharide-Triggered TLR4 Signaling
    Authors: H Lee, E Kim, S Kim
    Biomolecules, 2023-02-09;13(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model
    Authors: N Beckmann, A Neuhaus, S Zurbruegg, P Volkmer, C Patino, S Joller, D Feuerbach, A Doelemeyer, T Schweizer, S Rudin, U Neumann, R Berth, W Frieauff, F Gasparini, DR Shimshek
    Journal of Neuroinflammation, 2023-02-08;20(1):29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss
    Authors: J Guo, R Ren, Z Guo, K Sun, J He, J Shao, X Wang
    International immunopharmacology, 2023-02-07;116(0):109820.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease
    Authors: S De Scheppe, JZ Ge, G Crowley, LSS Ferreira, D Garceau, CE Toomey, D Sokolova, J Rueda-Carr, SH Shin, JS Kim, T Childs, T Lashley, JJ Burden, M Sasner, C Sala Frige, S Jung, S Hong
    Nature Neuroscience, 2023-02-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Micro Ribonucleic Acid-29a (miR-29a) Antagonist Normalizes Bone Metabolism in Osteogenesis Imperfecta (OI) Mice Model
    Authors: JY Ko, FS Wang, SH Chen, SJ Kuo
    Biomedicines, 2023-02-05;11(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Chemical mimetics of the N-degron pathway alleviate systemic inflammation by activating mitophagy and immunometabolic remodeling
    Authors: P Silwal, YJ Kim, YJ Lee, IS Kim, SM Jeon, T Roh, JK Kim, MJ Lee, JY Heo, DS Jo, SH Lee, DH Cho, JM Kim, YT Kwon, EK Jo
    Experimental & Molecular Medicine, 2023-02-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner Through Secreted Calpastatin
    Authors: Williams J, Irwin M, Li Y et al.
    Preprint
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget's disease of bone
    Authors: X Hu, SW Wong, K Liang, TH Wu, S Wang, L Wang, J Liu, M Yamauchi, BL Foster, JP Ting, B Zhao, HC Tseng, CC Ko
    Science Advances, 2023-01-27;9(4):eade6998.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Phosphatidylcholine Liposomes Reprogram Macrophages toward an Inflammatory Phenotype
    Authors: DM Cauvi, D Hawisher, J Derunes, A De Maio
    Membranes, 2023-01-21;13(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Obacunone targets macrophage migration inhibitory factor (MIF) to impede osteoclastogenesis and alleviate ovariectomy-induced bone loss
    Authors: J He, L Zheng, X Li, F Huang, S Hu, L Chen, M Jiang, X Lin, H Jiang, Y Zeng, T Ye, D Lin, Q Liu, J Xu, K Chen
    Journal of advanced research, 2023-01-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro
    Authors: J Zhu, Y Ma, J Wang, Y Wang, W Ali, H Zou, H Zhao, X Tong, R Song, Z Liu
    International Journal of Molecular Sciences, 2023-01-12;24(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  63. Osthole Inhibits M1 Macrophage Polarization and Attenuates Osteolysis in a Mouse Skull Model
    Authors: F Wang, P Yang, T Wan, C Liu, Y Zhu, X Chen, H Liu
    Oxidative Medicine and Cellular Longevity, 2023-01-12;2023(0):2975193.
  64. Isopsoralen suppresses receptor activator of nuclear factor kappa-beta ligand-induced osteoclastogenesis by inhibiting the NF-kappaB signaling
    Authors: W Zhan, B Ruan, H Dong, C Wang, S Wu, H Yu, X Xu, H Sun, J Cai
    PeerJ, 2023-01-10;11(0):e14560.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Phosphatidyl Inositol 3-Kinase (PI3K)-Inhibitor CDZ173 protects against LPS-induced osteolysis
    Authors: Z Wu, X Li, X Chen, X He, Y Chen, L Zhang, Z Li, M Yang, G Yuan, B Shi, N Chen, N Li, H Feng, M Zhou, G Rui, F Xu, R Xu
    Frontiers in Pharmacology, 2023-01-06;13(0):1021714.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  66. The role played by ailanthone in inhibiting bone metastasis of breast cancer by regulating tumor-bone microenvironment through the RANKL-dependent pathway
    Authors: Y Wang, Z Zhong, M Ma, Y Zhao, C Zhang, Z Qian, B Wang
    Frontiers in Pharmacology, 2023-01-05;13(0):1081978.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  67. IL-1 Generated by Oral Squamous Cell Carcinoma Stimulates Tumor-Induced and RANKL-Induced Osteoclastogenesis: A Possible Mechanism of Bone Resorption Induced by the Infiltration of Oral Squamous Cell Carcinoma
    Authors: Y Fukawa, K Kayamori, M Tsuchiya, T Ikeda
    International Journal of Molecular Sciences, 2022-12-30;24(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  68. Nanoparticle delivery of CD40 siRNA suppresses alloimmune responses by inhibiting activation and differentiation of DCs and macrophages
    Authors: J Wang, K Mao, X Cong, H Tan, C Wu, Z Hu, YG Yang, T Sun
    Science Advances, 2022-12-21;8(51):eabq3699.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  69. Mechanistic target of rapamycin complex 1 orchestrates the interplay between hepatocytes and Kupffer cells to determine the outcome of immune-mediated hepatitis
    Authors: X Sun, Y Ni, Q Lu, Y Liang, M Gu, X Xue, C Dai
    Cell Death & Disease, 2022-12-09;13(12):1031.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Polysaccharides from Annona�muricata leaves protect against cisplatin?induced cytotoxicity in macrophages by alleviating mitochondrial dysfunction
    Authors: JM Han, HY Song, KI Kim, WY Park, SH Park, EB Byun, EH Byun
    Molecular Medicine Reports, 2022-12-01;27(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Double knockin mice show NF-kappaB trajectories in immune signaling and aging
    Authors: SMT Rahman, M Aqdas, EW Martin, F Tomassoni, P Songkiatis, KS Oh, S Uderhardt, S Yun, QC Claybourne, RA McDevitt, V Greco, RN Germain, L Tessarollo, MH Sung
    Cell Reports, 2022-11-22;41(8):111682.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Evaluation of culture conditions for osteoclastogenesis in RAW264.7 cells
    Authors: Y Cheng, H Liu, J Li, Y Ma, C Song, Y Wang, P Li, Y Chen, Z Zhang
    PLoS ONE, 2022-11-17;17(11):e0277871.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer
    Authors: CY Chang, R You, D Armstrong, A Bandi, YT Cheng, PM Burkhardt, L Becerra-Do, MC Madison, HY Tung, Z Zeng, Y Wu, L Song, PE Phillips, P Porter, JM Knight, N Putluri, X Yuan, DC Marcano, EA McHugh, JM Tour, A Catic, L Maneix, BM Burt, HS Lee, DB Corry, F Kheradmand
    Science Advances, 2022-11-16;8(46):eabq0615.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Microglial WNT5A supports dendritic spines maturation and neuronal firing
    Authors: H Yeh, M Woodbury, K Ingraham-D, T Ikezu, S Ikezu
    Brain, Behavior, and Immunity, 2022-11-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration
    Authors: C Lin, Q Yang, D Guo, J Xie, YS Yang, S Chaugule, N DeSouza, WT Oh, R Li, Z Chen, AA John, Q Qiu, LJ Zhu, MB Greenblatt, S Ghosh, S Li, G Gao, C Haynes, CP Emerson, JH Shim
    Nature Communications, 2022-11-11;13(1):6869.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis
    Authors: HK Kwon, KE Yu, SV Cahill, KD Alder, CM Dussik, SH Kim, L Sharma, J Back, I Oh, FY Lee
    Embo Molecular Medicine, 2022-11-10;0(0):e15284.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. von Willebrand factor links primary hemostasis to innate immunity
    Authors: C Drakeford, S Aguila, F Roche, K Hokamp, J Fazavana, MP Cervantes, AM Curtis, HC Hawerkamp, SPS Dhami, H Charles-Me, EE Hackett, A Chion, S Ward, A Ahmad, I Schoen, E Breen, J Keane, R Murphy, RJS Preston, JM O'Sullivan, FJ Sheedy, P Fallon, JS O'Donnell
    Nature Communications, 2022-11-03;13(1):6320.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Berbamine inhibits RANKL- and M-CSF-mediated osteoclastogenesis and alleviates ovariectomy-induced bone loss
    Authors: G Qi, Z Jiang, W Lu, D Li, W Chen, X Yang, L Ding, H Yuan
    Frontiers in Pharmacology, 2022-11-02;13(0):1032866.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    Authors: K Nagano, K Yamana, H Saito, R Kiviranta, AC Pedroni, D Raval, C Niehrs, F Gori, R Baron
    Elife, 2022-11-02;11(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Divergent regulation of basement membrane trafficking by human macrophages and cancer cells
    Authors: JC Bahr, XY Li, TY Feinberg, L Jiang, SJ Weiss
    Nature Communications, 2022-10-27;13(1):6409.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. High Cholesterol-Induced Bone Loss Is Attenuated by Arctiin via an Action in Osteoclasts
    Authors: G Li, JN Park, HJ Park, JH Suh, HS Choi
    Nutrients, 2022-10-25;14(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Brain milieu induces early microglial maturation through the BAX-Notch axis
    Authors: F Zhao, J He, J Tang, N Cui, Y Shi, Z Li, S Liu, Y Wang, M Ma, C Zhao, L Luo, L Li
    Nature Communications, 2022-10-17;13(1):6117.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function
    Authors: JX Sun, KY Zhu, YM Wang, DJ Wang, MZ Zhang, H Sarlus, I Benito-Cue, XQ Zhao, ZF Zou, QY Zhong, Y Feng, S Wu, YQ Wang, RA Harris, J Wang
    Acta pharmacologica Sinica, 2022-10-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
  84. Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses
    Authors: AP Shaik, AS Shaik, M Abudawood, A Al Faraj
    BioMed Research International, 2022-10-06;2022(0):9470845.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling
    Authors: M Tomimatsu, K Matsumoto, M Ashizuka, S Kumagai, S Tanaka, T Nakae, K Yokota, S Kominami, R Kajiura, D Okuzaki, D Motooka, A Shiraishi, T Abe, H Matsuda, Y Okada, M Maeda, S Seno, M Obana, Y Fujio
    Scientific Reports, 2022-10-05;12(1):16656.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  86. HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction
    Authors: Q Li, T Yue, X Du, Z Tang, J Cui, W Wang, W Xia, B Ren, S Kan, C Li, C Wu, X Niu, B Li, K Lin, J Luo, G Chen, Z Wang
    Cell Death and Differentiation, 2022-10-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In Vivo
    Authors: MH Wu, WB Hsu, MH Chen, CS Shi
    Biomedicines, 2022-09-21;10(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. LysM-positive neurons drive Tuberous Sclerosis Complex (TSC)-associated brain lesions
    Authors: J Zhang, S Xu, K Liang, X Cao, Z Ye, W Huang, X Bai, Y Zhang
    Cellular Signalling, 2022-09-15;0(0):110468.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis
    Authors: W Zhu, W Liang, H Lu, L Chang, J Zhang, YE Chen, Y Guo
    Cells, 2022-09-15;11(18):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. N6-methyladenosine of Socs1 modulates macrophage inflammatory response in different stiffness environments
    Authors: Z Hu, Y Li, W Yuan, L Jin, WK Leung, C Zhang, Y Yang
    International journal of biological sciences, 2022-09-11;18(15):5753-5769.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Dietary 7-ketocholesterol exacerbates myocardial ischemia-reperfusion injury in mice through monocyte/macrophage-mediated inflammation
    Authors: T Uchikawa, T Matoba, T Kawahara, I Baba, S Katsuki, JI Koga, Y Hashimoto, R Yamasaki, I Ichi, H Akita, H Tsutsui
    Scientific Reports, 2022-09-01;12(1):14902.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  92. Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer
    Authors: YF Wang, L Yu, ZL Hu, YF Fang, YY Shen, MF Song, Y Chen
    Cell Death & Disease, 2022-08-29;13(8):748.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Succinate and inosine coordinate innate immune response to bacterial infection
    Authors: M Jiang, ZG Chen, H Li, TT Zhang, MJ Yang, XX Peng, B Peng
    PloS Pathogens, 2022-08-26;18(8):e1010796.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  94. Peimine suppresses collagen-induced arthritis, activated fibroblast-like synoviocytes and TNFalpha-induced MAPK pathways
    Authors: J Zhou, Y Mao, X Shi, Y Zhang, X Yu, X Liu, L Diao, X Yang, C Liu, D Liu, X Tan, M Liu
    International immunopharmacology, 2022-08-24;111(0):109181.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing
    Authors: Y Inoue, CW Liao, Y Tsunakawa, IL Tsai, S Takahashi, M Hamada
    International Journal of Molecular Sciences, 2022-08-19;23(16):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  96. Graphene oxide/gallium nanoderivative as a multifunctional modulator of osteoblastogenesis and osteoclastogenesis for the synergistic therapy of implant-related bone infection
    Authors: Y Yang, M Li, B Zhou, X Jiang, D Zhang, H Luo
    Bioactive materials, 2022-07-21;25(0):594-614.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses
    Authors: Y Wu, H Wen, ZJ Bernstein, KM Hainline, TS Blakney, KL Congdon, DJ Snyder, JH Sampson, L Sanchez-Pe, JH Collier
    Science Advances, 2022-07-20;8(29):eabm7833.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Periosteal stem cells control growth plate stem cells during postnatal skeletal growth
    Authors: M Tsukasaki, N Komatsu, T Negishi-Ko, NC Huynh, R Muro, Y Ando, Y Seki, A Terashima, W Pluemsakun, T Nitta, T Nakamura, T Nakashima, S Ohba, H Akiyama, K Okamoto, R Baron, H Takayanagi
    Oncogene, 2022-07-18;13(1):4166.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Mechanical force regulates root resorption in rats through RANKL and OPG
    Authors: J Zhou, L Guo, Y Yang, Y Liu, C Zhang
    BMC Oral Health, 2022-07-16;22(1):290.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. A Novel Inhibitor INF 39 Promotes Osteogenesis via Blocking the NLRP3/IL-1beta Axis
    Authors: W Chen, P Tang, S Fan, X Jiang
    BioMed Research International, 2022-07-13;2022(0):7250578.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants
    Authors: T Hoyler, B Bannert, C André, D Beck, T Boulay, D Buffet, N Caesar, T Calzascia, J Dawson, D Kyburz, R Hennze, C Huppertz, A Littlewood, P Loetscher, KD Mertz, S Niwa, G Robert, JS Rush, G Ruzzante, S Sarret, T Stein, I Touil, G Wieczorek, G Zipfel, S Hawtin, T Junt
    JCI Insight, 2022-07-08;7(13):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Interleukin-19 Promotes Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy
    Authors: J Zou, W Tan, B Li, Z Wang, Y Li, J Zeng, B Jiang, S Yoshida, Y Zhou
    Investigative Ophthalmology & Visual Science, 2022-07-08;63(8):9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation
    Authors: R Guo, X Jia, Z Ding, G Wang, M Jiang, B Li, S Chen, B Xia, Q Zhang, J Liu, R Zheng, Z Gao, X Xie
    Theranostics, 2022-07-04;12(11):5220-5236.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Suppression of osteoclast multinucleation via a posttranscriptional regulation-based spatiotemporally selective delivery system
    Authors: Q Wang, H Wang, H Yan, H Tian, Y Wang, W Yu, Z Dai, P Chen, Z Liu, R Tang, C Jiang, S Fan, X Liu, X Lin
    Oncogene, 2022-06-29;8(26):eabn3333.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis
    Authors: D Azimova, N Herrera, L Duvenage, M Voorhies, RA Rodriguez, BC English, JC Hoving, O Rosenberg, A Sil
    Oncogene, 2022-06-22;18(6):e1010417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev-Erbalpha in osteoblasts
    Authors: Y Tian, J Ming
    Oncogene, 2022-06-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway
    Authors: Z Jie, S Wang, Q Ma, Y Shen, X Zhao, H Yu, Z Xie, C Jiang
    Journal of Bone Oncology, 2022-06-11;35(0):100439.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Long noncoding RNA Gm31629 promotes bone regeneration by maintaining bone marrow mesenchymal stem cells activity
    Authors: G Cai, Y Xiao, M Yang, Q Guo, T Su, Y Liu, T Jiang, C Li
    PeerJ, 2022-06-09;10(0):e13475.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages
    Authors: H Li, D Qiu, Y Yuan, X Wang, F Wu, H Yang, S Wang, M Ma, Y Qian, B Zhan, X Yang
    Oncogene, 2022-06-09;109(0):108907.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Targeting parvalbumin promotes M2 macrophage polarization and energy expenditure in mice
    Authors: S Lin, A Zhang, L Yuan, Y Wang, C Zhang, J Jiang, H Xu, H Yuan, H Yao, Q Zhang, Y Zhang, M Lou, P Wang, ZN Zhang, B Luan
    Nature Communications, 2022-06-08;13(1):3301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
    Authors: H Qu, R Heinbäck, H Salo, E Ewing, A Espinosa, C Aulin, H Erlandsson
    Biomolecules, 2022-06-02;12(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. NLRP3 Inflammasome Negatively Regulates RANKL-Induced Osteoclastogenesis of Mouse Bone Marrow Macrophages but Positively Regulates It in the Presence of Lipopolysaccharides
    Authors: MI Alam, M Mae, F Farhana, M Oohira, Y Yamashita, Y Ozaki, E Sakai, A Yoshimura
    Oncogene, 2022-05-29;23(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1
    Authors: Y Zhang, M Yang, S Zhang, Z Yang, Y Zhu, Y Wang, Z Chen, X Lv, Z Huang, Y Xie, L Cai
    Cell & bioscience, 2022-05-26;12(1):70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Anoctamin 1 controls bone resorption by coupling Cl- channel activation with RANKL-RANK signaling transduction
    Authors: W Sun, S Guo, Y Li, J Li, C Liu, Y Chen, X Wang, Y Tan, H Tian, C Wang, R Du, G Zhong, S Shi, B Ma, C Qu, J Fu, X Jin, D Zhao, Y Zhan, S Ling, H An, Y Li
    Nature Communications, 2022-05-24;13(1):2899.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Carnosol inhibits osteoclastogenesis in�vivo and in�vitro by blocking the RANKL?induced NF?kappaB signaling pathway
    Authors: P Cai, S Yan, Y Lu, X Zhou, X Wang, M Wang, Z Yin
    Molecular Medicine Reports, 2022-05-20;26(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts
    Authors: N Matsumoto, M Sekiya, GH Sun-Wada, Y Wada, M Nakanishi-
    Scientific Reports, 2022-05-19;12(1):8455.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Locally Secreted Semaphorin 4D Is Engaged in Both Pathogenic Bone Resorption and Retarded Bone Regeneration in a Ligature-Induced Mouse Model of Periodontitis
    Authors: T Ishii, M Ruiz-Torru, K Yamamoto, T Yamaguchi, A Heidari, R Pierrelus, E Leon, S Shindo, M Rawas-Qala, MR Pastore, A Ikeda, S Nakamura, H Mawardi, U Kandalam, P Hardigan, L Witek, PG Coelho, T Kawai
    International Journal of Molecular Sciences, 2022-05-18;23(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Gut Metabolite Urolithin A Inhibits Osteoclastogenesis and Senile Osteoporosis by Enhancing the Autophagy Capacity of Bone Marrow Macrophages
    Authors: H Tao, Y Tao, C Yang, W Li, W Zhang, X Li, Y Gu, Y Hong, H Yang, Y Liu, X Yang, D Geng
    Frontiers in Pharmacology, 2022-05-12;13(0):875611.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  119. Epac1 activation by cAMP regulates cellular SUMOylation and promotes the formation of biomolecular condensates
    Authors: W Yang, WG Robichaux, FC Mei, W Lin, L Li, S Pan, MA White, Y Chen, X Cheng
    Science Advances, 2022-04-20;8(16):eabm2960.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Network Pharmacology Deciphers the Action of Bioactive Polypeptide in Attenuating Inflammatory Osteolysis via the Suppression of Oxidative Stress and Restoration of Bone Remodeling Balance
    Authors: Z Cui, C Feng, J Chen, Y Wang, Q Meng, S Zhao, Y Zhang, D Feng, Z Li, S Sun
    Oxidative Medicine and Cellular Longevity, 2022-04-14;2022(0):4913534.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Erythrocyte-derived extracellular vesicles aggravate inflammation by promoting the proinflammatory macrophage phenotype through TLR4-MyD88-NF-kappaB-MAPK pathway
    Authors: Y Gao, H Jin, H Tan, X Cai, Y Sun
    Journal of leukocyte biology, 2022-04-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  122. Osteoclast formation from mouse bone marrow cells on micro/nano-scale patterned surfaces
    Authors: T Akasaka, H Hayashi, M Tamai, Y Yoshimura, YI Tagawa, H Miyaji, K Nakanishi, Y Yoshida
    Journal of oral biosciences, 2022-04-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Chemical Modulation of SQSTM1/p62-mediated Xenophagy that Targets a Broad Range of Pathogenic Bacteria
    Authors: YJ Lee, JK Kim, CH Jung, YJ Kim, EJ Jung, SH Lee, HR Choi, YS Son, SM Shim, SM Jeon, JH Choe, SH Lee, J Whang, KC Sohn, GM Hur, HT Kim, J Yeom, EK Jo, YT Kwon
    Autophagy, 2022-04-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  124. Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFkappaB p65 pathway
    Authors: T Shi, Y Shi, H Gao, Y Ma, Q Wang, S Shen, X Shao, W Gong, X Chen, J Qin, J Wu, Q Jiang, B Xue
    Journal of Orthopaedic Translation, 2022-04-04;35(0):1-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation
    Authors: X Chen, C Li, X Cao, X Jia, X Chen, Z Wang, W Xu, F Dai, S Zhang
    Theranostics, 2022-04-04;12(7):3251-3272.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. 7-Ketocholesterol-Induced Micro-RNA-107-5p Increases Number and Activity of Osteoclasts by Targeting MKP1
    Authors: G Li, OJ Sul, R Yu, HS Choi
    International Journal of Molecular Sciences, 2022-03-28;23(7):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  127. TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss
    Authors: C Yang, H Tao, H Zhang, Y Xia, J Bai, G Ge, W Li, W Zhang, L Xiao, Y Xu, Z Wang, Y Gu, H Yang, Y Liu, D Geng
    Autophagy, 2022-03-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  128. P2X7 receptor knockdown suppresses osteoclast differentiation by inhibiting autophagy and Ca2+/calcineurin signaling
    Authors: Y Ma, R Di, H Zhao, R Song, H Zou, Z Liu
    Molecular Medicine Reports, 2022-03-10;25(5):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  129. Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis
    Authors: H Zuo, Y Wan
    Cancer Gene Therapy, 2022-03-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Piperlongumine Inhibits Titanium Particles-Induced Osteolysis, Osteoclast Formation, and RANKL-Induced Signaling Pathways
    Authors: X Liu, L Diao, Y Zhang, X Yang, J Zhou, Y Mao, X Shi, F Zhao, M Liu
    International Journal of Molecular Sciences, 2022-03-05;23(5):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production
    Authors: Q Guo, H Zhao, H Cheng, H Kang, Y Dong, R Peng, M Zhu, Z Fang, F Li
    The Journal of Biological Chemistry, 2022-03-04;0(0):101775.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Plumbagin is a NF-kappaB-Inducing Kinase Inhibitor with Dual Anabolic and Anti-Resorptive Effects that Prevents Menopausal-Related Osteoporosis in Mice
    Authors: G Shen, X Liu, W Lei, R Duan, Z Yao
    The Journal of Biological Chemistry, 2022-02-27;0(0):101767.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Amino acids suppress macropinocytosis and promote release of CSF1 receptor in macrophages
    Authors: ZI Mendel, MB Reynolds, BH Abuaita, MX O'Riordan, JA Swanson
    Journal of Cell Science, 2022-02-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  134. The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific
    Authors: V Mela, A Sayd Gaban, E O'Neill, S Bechet, A Walsh, MA Lynch
    Cells, 2022-02-18;11(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes
    Authors: JM Kim, YS Yang, J Xie, O Lee, J Kim, J Hong, B Boldyreff, O Filhol, H Chun, MB Greenblatt, G Gao, JH Shim
    Cell Death and Differentiation, 2022-02-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Dual-sgRNA CRISPR/Cas9 knockout of PD-L1 in human U87 glioblastoma tumor cells inhibits proliferation, invasion, and tumor-associated macrophage polarization
    Authors: J Fierro, J DiPasquale, J Perez, B Chin, Y Chokpapone, AM Tran, A Holden, C Factoriza, N Sivagnanak, R Aguilar, S Mazal, M Lopez, H Dou
    Scientific Reports, 2022-02-14;12(1):2417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Divalent metal cations stimulate skeleton interoception for new bone formation in mouse injury models
    Authors: W Qiao, D Pan, Y Zheng, S Wu, X Liu, Z Chen, M Wan, S Feng, KMC Cheung, KWK Yeung, X Cao
    Nature Communications, 2022-01-27;13(1):535.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
    Authors: KK Richardson, W Ling, K Krager, Q Fu, SD Byrum, R Pathak, N Aykin-Burn, HN Kim
    International Journal of Molecular Sciences, 2022-01-08;23(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  139. miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1
    Authors: SJ Hwang, BJ Ahn, MW Shin, YS Song, Y Choi, GT Oh, KW Kim, HJ Lee
    Cell Death and Differentiation, 2022-01-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Bortezomib Rescues Ovariectomy-Induced Bone Loss via SMURF-Mediated Ubiquitination Pathway
    Authors: Y Fang, Y Liu, Z Zhao, Y Lu, X Shen, T Zhu, M Hou, F He, H Yang, Y Zhang, Q Shi, X Zhu
    Oxidative Medicine and Cellular Longevity, 2021-12-31;2021(0):9661200.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds
    Authors: SW Shin, YS Hwang
    Nutrients, 2021-12-28;14(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. SIRT6 inhibition delays peripheral nerve recovery by suppressing migration, phagocytosis and M2-polarization of macrophages
    Authors: Y Zou, J Zhang, J Xu, L Fu, Y Xu, X Wang, Z Li, L Zhu, H Sun, H Zheng, J Guo
    Cell & bioscience, 2021-12-14;11(1):210.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Galectin-3 Contributes to the Inhibitory Effect of lalpha,25-(OH)2D3 on Osteoclastogenesis
    Authors: J Gu, X Zhang, C Zhang, Y Li, J Bian, X Liu, Y Yuan, H Zou, X Tong, Z Liu
    International Journal of Molecular Sciences, 2021-12-11;22(24):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis
    Authors: M Mae, MI Alam, Y Yamashita, Y Ozaki, K Higuchi, SM Ziauddin, JL Montenegro, E Sakai, T Tsukuba, A Yoshimura
    International Journal of Molecular Sciences, 2021-11-18;22(22):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
    Authors: E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, SH Nam, JW Lee
    Cell Reports, 2021-11-16;37(7):110018.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3
    Authors: Y Zhang, S Zhang, Y Wang, Z Yang, Z Chen, N Wen, M Yang, Z Huang, Y Xie, L Cai
    Oxidative Medicine and Cellular Longevity, 2021-11-15;2021(0):2896674.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Jintiange Capsules Ameliorate Osteoarthritis by Modulating Subchondral Bone Remodeling and Protecting Cartilage Against Degradation
    Authors: C Zhuang, Z Wang, W Chen, H Wang, B Tian, H Lin
    Frontiers in Pharmacology, 2021-11-11;12(0):762543.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response
    Authors: AE Hinman, C Jani, SC Pringle, WR Zhang, N Jain, AJ Martinot, AK Barczak
    Elife, 2021-11-10;10(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. CNC-bZIP protein NFE2L1 regulates osteoclast differentiation in antioxidant-dependent and independent manners
    Authors: Z Liu, H Wang, Y Hou, Y Yang, J Jia, J Wu, Z Zuo, T Gao, S Ren, Y Bian, S Liu, J Fu, Y Sun, J Li, M Yamamoto, Q Zhang, Y Xu, J Pi
    Redox Biology, 2021-11-06;48(0):102180.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity
    Authors: RD Hu, W Zhang, L Li, ZQ Zuo, M Ma, JF Ma, TT Yin, CY Gao, SH Yang, ZB Zhao, ZJ Li, GB Qiao, ZX Lian, K Qu
    Cell Death & Disease, 2021-10-29;12(11):1023.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation
    Authors: JM Motta, VM Rumjanek, A Mantovani, M Locati
    Biomedicines, 2021-10-04;9(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  152. Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury
    Authors: J Amo-Aparic, J Garcia-Gar, I Francos-Qu, A Urpi, A Esteve-Cod, M Gut, A Quintana, R Lopez-Vale
    Theranostics, 2021-10-03;11(20):9805-9820.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis
    Authors: H Muto, T Ito, T Tanaka, S Yokoyama, K Yamamoto, N Imai, Y Ishizu, K Maeda, T Honda, T Ishikawa, A Kato, T Ohshiro, F Kano, A Yamamoto, K Sakai, H Hibi, M Ishigami, M Fujishiro
    Scientific Reports, 2021-09-21;11(1):18778.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
    Authors: S Jiang, NM Maphis, J Binder, D Chisholm, L Weston, W Duran, C Peterson, A Zimmerman, MA Mandell, SD Jett, E Bigio, C Geula, N Mellios, JP Weick, GA Rosenberg, E Latz, MT Heneka, K Bhaskar
    Cell Reports, 2021-09-21;36(12):109720.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Ang II-Induced Hypertension Exacerbates the Pathogenesis of Tuberculosis
    Authors: SN Cho, JA Choi, J Lee, SH Son, SA Lee, TD Nguyen, SY Choi, CH Song
    Cells, 2021-09-19;10(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Myeloid Lineage Ablation of Phlpp1 Regulates M-CSF Signaling and Tempers Bone Resorption in Female Mice
    Authors: IY Karkache, JR Damodaran, DHH Molstad, KC Mansky, EW Bradley
    International Journal of Molecular Sciences, 2021-09-08;22(18):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Danlou Tablets Inhibit Atherosclerosis in Apolipoprotein E-Deficient Mice by Inducing Macrophage Autophagy: The Role of the PI3K-Akt-mTOR Pathway
    Authors: C Liu, G Chen, Y Chen, Y Dang, G Nie, D Wu, J Li, Z Chen, H Yang, D He, X Li, J Sun, J Lu, L Wang
    Frontiers in Pharmacology, 2021-09-08;12(0):724670.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia
    Authors: JA Carroll, B Race, K Williams, JF Striebel, B Chesebro
    Journal of Neuroinflammation, 2021-09-06;18(1):194.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. The MEMIC is an ex vivo system to model the complexity of the tumor microenvironment
    Authors: L Janská, L Anandi, NC Kirchberge, ZS Marinkovic, LT Schachtner, G Guzelsoy, C Carmona-Fo
    Disease Models & Mechanisms, 2021-08-18;14(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. RSPO3 is important for trabecular bone and fracture risk in mice and humans
    Authors: KH Nilsson, P Henning, ME Shahawy, M Nethander, TL Andersen, C Ejersted, J Wu, KL Gustafsson, A Koskela, J Tuukkanen, PPC Souza, J Tuckermann, M Lorentzon, LE Ruud, T Lehtimäki, JH Tobias, S Zhou, UH Lerner, JB Richards, S Movérare-S, C Ohlsson
    Nature Communications, 2021-08-13;12(1):4923.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Diterbutyl phthalate attenuates osteoarthritis in ACLT mice via suppressing ERK/c-fos/NFATc1 pathway, and subsequently inhibiting subchondral osteoclast fusion
    Authors: C Fang, JW Guo, YJ Wang, XQ Li, H Zhang, J Cui, Y Hu, YY Jing, X Chen, JC Su
    Acta pharmacologica Sinica, 2021-08-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Rufomycin Exhibits Dual Effects Against Mycobacterium abscessus Infection by Inducing Host Defense and Antimicrobial Activities
    Authors: CR Park, S Paik, YJ Kim, JK Kim, SM Jeon, SH Lee, J Whang, J Cheng, JW Suh, J Cao, G Shetye, SN Chen, J McAlpine, GF Pauli, S Franzblau, S Cho, EK Jo
    Frontiers in Microbiology, 2021-08-10;12(0):695024.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy
    Authors: DK Fix, HA Ekiz, JJ Petrocelli, AM Mckenzie, ZS Mahmassani, RM O'Connell, MJ Drummond
    Aging Cell, 2021-08-08;0(0):e13448.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
    Authors: MG Dorrington, CJ Bradfield, JB Lack, B Lin, SP John, JJ Liang, T Starr, O Ernst, JL Gross, J Sun, AH Miller, O Steele-Mor, IDC Fraser
    PloS Pathogens, 2021-08-04;17(8):e1009821.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. STING suppresses bone cancer pain via immune and neuronal modulation
    Authors: K Wang, CR Donnelly, C Jiang, Y Liao, X Luo, X Tao, S Bang, A McGinnis, M Lee, MJ Hilton, RR Ji
    Nature Communications, 2021-07-27;12(1):4558.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis
    Authors: X Guo, J Bai, G Ge, Z Wang, Q Wang, K Zheng, H Tao, L Zhang, H Zhang, D Wang, X Zhang, H Li, G Pan, D Geng
    Journal of colloid and interface science, 2021-07-24;605(0):410-424.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C
    Authors: TT Chu, X Tu, K Yang, J Wu, JJ Repa, N Yan
    Nature, 2021-07-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. N-3-Hydroxy Dodecanoyl-DL-homoserine Lactone (OH-dDHL) Triggers Apoptosis of Bone Marrow-Derived Macrophages through the ER- and Mitochondria-Mediated Pathways
    Authors: K Woo, DH Kim, MH Oh, HS Park, CH Choi
    International Journal of Molecular Sciences, 2021-07-15;22(14):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Protective Effect of Polysaccharides Extracted from Cudrania tricuspidata Fruit against Cisplatin-Induced Cytotoxicity in Macrophages and a Mouse Model
    Authors: EB Byun, HY Song, WS Kim, JM Han, HS Seo, SH Park, K Kim, EH Byun
    International Journal of Molecular Sciences, 2021-07-13;22(14):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  170. The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt
    Authors: AS Tooley, D Kazyken, C Bodur, IE Gonzalez, DC Fingar
    The Journal of Biological Chemistry, 2021-07-08;0(0):100942.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Development of a Macrophage-Based ADCC Assay
    Authors: MB Uccellini, S Aslam, STH Liu, F Alam, A García-Sas
    Vaccines, 2021-06-17;9(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Patchouli Alcohol Modulates the Pregnancy X Receptor/Toll-like Receptor 4/Nuclear Factor Kappa B Axis to Suppress Osteoclastogenesis
    Authors: Q Lu, C Jiang, J Hou, H Qian, F Chu, W Zhang, M Ye, Z Chen, J Liu, H Yao, J Zhang, J Xu, T Wang, S Fan, Q Wang
    Frontiers in Pharmacology, 2021-06-08;12(0):684976.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  173. Astragalus polysaccharide attenuates LPS-related inflammatory osteolysis by suppressing osteoclastogenesis by reducing the MAPK signalling pathway
    Authors: J Yang, L Qin, J Huang, Y Li, S Xu, H Wang, S Zhu, J Wang, B Zhu, F Li, W Huang, X Gong, N Hu
    Journal of Cellular and Molecular Medicine, 2021-06-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  174. Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns
    Authors: H Salo, H Qu, D Mitsiou, H Aucott, J Han, XM Zhang, C Aulin, H Erlandsson
    Biomolecules, 2021-05-28;11(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  175. 7-ketocholesterol enhances autophagy via the ROS-TFEB signaling pathway in osteoclasts: 7-KC in osteoclasts
    Authors: OJ Sul, G Li, JE Kim, ES Kim, HS Choi
    The Journal of nutritional biochemistry, 2021-05-21;0(0):108783.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions
    Authors: D Zhang, J Huang, F Wang, H Ding, Y Cui, Y Yang, J Xu, H Luo, Y Gao, L Pan, Y Wu, Y Gong, L Xie, Z Liu, Y Qu, L Zhang, W Liu, W Zhang, S Zhao, Q Yi, T Niu, Y Zheng
    Cell Death & Disease, 2021-05-15;12(5):495.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Multi-Functional MPT Protein as a Therapeutic Agent against Mycobacterium tuberculosis
    Authors: JS Kim, E Cho, SJ Mun, S Kim, SY Kim, DG Kim, W Son, HI Jeon, HK Kim, YJ Jeong, S Jang, HS Kim, CS Yang
    Biomedicines, 2021-05-13;9(5):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Plastrum testudinis extract suppresses osteoclast differentiation via the NF-&kappaB signaling pathway and ameliorates senile osteoporosis
    Authors: H Chen, G Shen, Q Shang, P Zhang, D Yu, X Yu, Z Zhang, W Zhao, Z Wu, F Tang, Liang, X Jiang, H Ren
    Journal of ethnopharmacology, 2021-05-08;276(0):114195.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. BCG Cell Wall Skeleton As a Vaccine Adjuvant Protects Both Infant and Old-Aged Mice from Influenza Virus Infection
    Authors: KH Kim, YT Lee, Y Park, EJ Ko, YJ Jung, YJ Kim, EK Jo, SM Kang
    Biomedicines, 2021-05-05;9(5):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. PP2Ac&alpha promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNF&alpha production
    Authors: Y Liang, X Sun, M Wang, Q Lu, M Gu, L Zhou, Q Hou, M Tan, S Wang, X Xue, C Dai
    Cell Death and Differentiation, 2021-05-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response
    Authors: P Xue, X Hu, E Chang, L Wang, M Chen, TH Wu, DJ Lee, BL Foster, HC Tseng, CC Ko
    Experimental & Molecular Medicine, 2021-04-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Inhibition of Sirtuin 3 prevents titanium particle-induced bone resorption and osteoclastsogenesis via suppressing ERK and JNK signaling
    Authors: N Li, X Li, K Zheng, J Bai, W Zhang, H Sun, G Ge, W Wang, Z Wang, Y Gu, Y Xue, Y Xu, D Geng, J Zhou
    International journal of biological sciences, 2021-04-03;17(5):1382-1394.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses
    Authors: MJ Strowitzki, G Kimmer, JS Wehrmann, AS Ritter, P Radhakrish, VM Opitz, C Tuffs, M Biller, J Kugler, U Keppler, JM Harnoss, J Klose, T Schmidt, A Blanco, CT Taylor, M Schneider
    JCI Insight, 2021-03-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis
    Authors: X Liu, Y Chai, G Liu, W Su, Q Guo, X Lv, P Gao, B Yu, G Ferbeyre, X Cao, M Wan
    Nature Communications, 2021-03-23;12(1):1832.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
    Authors: MG Dorrington, CJ Bradfield, JB Lack, B Lin, JJ Liang, T Starr, O Ernst, JL Gross, J Sun, AH Miller, O Steele-Mor, IDC Fraser
    PloS Pathogens, 2021-03-08;17(3):e1009395.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. p300/CBP inhibitor A-485 inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss
    Authors: S Huo, X Liu, S Zhang, Z Lyu, J Zhang, Y Wang, B Nie, B Yue
    International immunopharmacology, 2021-02-21;94(0):107458.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Schistosoma�japonicum cystatin suppresses osteoclastogenesis via manipulating the NF?&kappaB signaling pathway
    Authors: Y Chen, B Wei, P Xu, H Tang, L Yang, Y Wang, Y Fu, X Yang, Y Mao
    Molecular Medicine Reports, 2021-02-12;23(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Development of a method for the identification of receptor activator of nuclear factor-&kappaB+ populations in vivo
    Authors: M Kawakami, H Yasuda, D Nishida, A Katakura, T Mizoguchi
    Journal of oral biosciences, 2021-01-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Airway-Associated Macrophages in Homeostasis and Repair
    Authors: AE Engler, AB Ysasi, RMF Pihl, C Villacorta, HM Heston, HMK Richardson, BR Thapa, NR Moniz, AC Belkina, SA Mazzilli, JR Rock
    Cell Reports, 2020-12-29;33(13):108553.
    Species: Transgenic Mouse
    Sample Types: Spheroid
    Applications: Bioassay
  190. CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice
    Authors: S Rosendahl, R Sulniute, M Eklund, C Koskinen H, MJO Johansson, E Kindstedt, S Lindquist, P Lundberg
    The Journal of Biological Chemistry, 2020-12-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  191. Oleate-induced aggregation of LC3 at the trans-Golgi network is linked to a protein trafficking blockade
    Authors: G Cerrato, M Leduc, K Müller, P Liu, L Zhao, J Humeau, W Xie, S Zhang, O Kepp, A Sauvat, G Kroemer
    Cell Death and Differentiation, 2020-12-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  192. The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Regulating CD4+ T Helper Cell Response
    Authors: G Gupta, Z Mou, P Jia, R Sharma, R Zayats, SM Viana, L Shan, A Barral, VS Boaventura, TT Murooka, A Soussi-Gou, CI de Oliveir, JE Uzonna
    Cell Reports, 2020-12-15;33(11):108513.
  193. Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells
    Authors: MJ Park, JA Baek, SY Kim, KA Jung, JW Choi, SH Park, SK Kwok, ML Cho
    Journal of Translational Medicine, 2020-12-14;18(1):483.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Overexpression of c-Fos reverses osteoprotegerin-mediated suppression of osteoclastogenesis by increasing the Beclin1-induced autophagy
    Authors: X Tong, M Chen, R Song, H Zhao, J Bian, J Gu, Z Liu
    Journal of Cellular and Molecular Medicine, 2020-12-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  195. Mycobacterium tuberculosis Rv2626c-derived peptide as a therapeutic agent for sepsis
    Authors: SY Kim, D Kim, S Kim, D Lee, SJ Mun, E Cho, W Son, K Jang, CS Yang
    Embo Molecular Medicine, 2020-12-01;12(12):e12497.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  196. Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-&kappaB Pathway
    Authors: Z Liu, Y Li, F Guo, C Zhang, G Song, J Yang, D Chen
    Mediators of Inflammation, 2020-11-27;2020(0):1926947.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  197. The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis
    Authors: M Timmen, H Hidding, M Götte, TE Khassawna, D Kronenberg, R Stange
    Sci Rep, 2020-11-25;10(1):20510.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  198. Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1&beta production
    Authors: G Yang, W Song, J Xu, JL Postoak, F Cheng, J Martinez, J Zhang, L Wu, L Van Kaer
    Cell Mol Immunol, 2020-11-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  199. Dopamine suppresses osteoclast differentiation via cAMP/PKA/CREB pathway
    Authors: L Wang, L Han, P Xue, X Hu, SW Wong, M Deng, HC Tseng, BW Huang, CC Ko
    Cell Signal, 2020-11-24;78(0):109847.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. M2 macrophage-derived exosomes promote angiogenesis and growth of pancreatic ductal adenocarcinoma by targeting E2F2
    Authors: Y Yang, Z Guo, W Chen, X Wang, M Cao, X Han, K Zhang, B Teng, J Cao, W Wu, P Cao, C Huang, Z Qiu
    Mol Ther, 2020-11-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  201. NLRP3 Inflammasome Activation Is Involved in LPA1-Mediated Brain Injury after Transient Focal Cerebral Ischemia
    Authors: CH Lee, A Sapkota, BP Gaire, JW Choi
    Int J Mol Sci, 2020-11-14;21(22):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  202. Toxoplasma gondii GRA9 Regulates the Activation of NLRP3 Inflammasome to Exert Anti-Septic Effects in Mice
    Authors: JS Kim, SJ Mun, E Cho, D Kim, W Son, HI Jeon, HK Kim, K Jang, CS Yang
    Int J Mol Sci, 2020-11-10;21(22):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  203. Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase
    Authors: AT Holdbrooks, KE Ankenbauer, J Hwang, SL Bellis
    PLoS ONE, 2020-11-09;15(11):e0241850.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  204. Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-&kappaB signaling pathways
    Authors: L Xiao, M Zhong, Y Huang, J Zhu, W Tang, D Li, J Shi, A Lu, H Yang, D Geng, H Li, Z Wang
    Aging (Albany NY), 2020-11-07;12(21):21706-21729.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  205. Transcriptomic profiling of feline teeth highlights the role of matrix metalloproteinase 9 (MMP9) in tooth resorption
    Authors: S Lee, SJ Bush, S Thorne, N Mawson, C Farquharso, GT Bergkvist
    Sci Rep, 2020-11-03;10(1):18958.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Cell Culture
  206. MAIR-II deficiency ameliorates cardiac remodelling post-myocardial infarction by suppressing TLR9-mediated macrophage activation
    Authors: S Yonebayash, K Tajiri, N Murakoshi, D Xu, S Li, D Feng, Y Okabe, Z Yuan, Z Song, K Aonuma, A Shibuya, K Aonuma, M Ieda
    J Cell Mol Med, 2020-11-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  207. Nepetin inhibits osteoclastogenesis by inhibiting RANKL-induced activation of NF-&kappaB and MAPK signalling pathway, and autophagy
    Authors: B Chu, S Chen, X Zheng, J Ye, X Cheng, L Zhang, D Guo, P Wang, D Hong, Z Hong
    J Cell Mol Med, 2020-11-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  208. The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone
    Authors: T Okui, M Hiasa, S Ryumon, K Ono, Y Kunisada, S Ibaragi, A Sasaki, GD Roodman, FA White, T Yoneda
    Journal of Bone Oncology, 2020-10-28;26(0):100330.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  209. CSF1R signaling is a regulator of pathogenesis in progressive MS
    Authors: N Hagan, JL Kane, D Grover, L Woodworth, C Madore, J Saleh, J Sancho, J Liu, Y Li, J Proto, M Zelic, A Mahan, M Kothe, AA Scholte, M Fitzgerald, B Gisevius, A Haghikia, O Butovsky, D Ofengeim
    Cell Death Dis, 2020-10-23;11(10):904.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Maackiain dampens osteoclastogenesis via attenuating RANKL-stimulated NF-&kappaB signalling pathway and NFATc1 activity
    Authors: Y Liu, W Zeng, C Ma, Z Wang, C Wang, S Li, W He, Q Zhang, J Xu, C Zhou
    J. Cell. Mol. Med., 2020-09-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk
    Authors: Z Najafova, P Liu, F Wegwitz, M Ahmad, L Tamon, RL Kosinsky, W Xie, SA Johnsen, J Tuckermann
    Cell Death Differ., 2020-09-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Sarsasapogenin Suppresses RANKL-Induced Osteoclastogenesis in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo
    Authors: J Peng, K Zhao, J Zhu, Y Wang, P Sun, Q Yang, T Zhang, W Han, W Hu, W Yang, J Ruan, Y Qian
    Drug Des Devel Ther, 2020-08-24;14(0):3435-3447.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. C9orf72 in myeloid cells suppresses STING-induced inflammation
    Authors: ME McCauley, JG O'Rourke, A Yáñez, JL Markman, R Ho, X Wang, S Chen, D Lall, M Jin, AKMG Muhammad, S Bell, J Landeros, V Valencia, M Harms, M Arditi, C Jefferies, RH Baloh
    Nature, 2020-08-19;585(7823):96-101.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis
    Authors: Z Qian, Z Zhong, S Ni, D Li, F Zhang, Y Zhou, Z Kang, J Qian, B Yu
    J. Cell. Mol. Med., 2020-08-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Tectoridin inhibits osteoclastogenesis and bone loss in a murine model of ovariectomy-induced osteoporosis
    Authors: J Wang, Y Tang, X Lv, J Zhang, B Ma, X Wen, Y Bao, G Wang
    Exp. Gerontol., 2020-08-13;140(0):111057.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Knockdown of Tcirg1 inhibits large-osteoclast generation by down-regulating NFATc1 and IP3R2 expression
    Authors: D Zhang, L Lin, B Yang, Z Meng, B Zhang
    PLoS ONE, 2020-08-13;15(8):e0237354.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  217. Collagen VIalpha2 chain deficiency causes trabecular bone loss by potentially promoting osteoclast differentiation through enhanced TNFalpha signaling
    Authors: HT Pham, V Kram, QA Dar, T Komori, Y Ji, P Mohassel, J Rooney, L Li, TM Kilts, C Bonnemann, S Lamande, MF Young
    Sci Rep, 2020-08-13;10(1):13749.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Extracellular vesicle-encapsulated IL-10 as novel nanotherapeutics against ischemic AKI
    Authors: TT Tang, B Wang, M Wu, ZL Li, Y Feng, JY Cao, D Yin, H Liu, RN Tang, SD Crowley, LL Lv, BC Liu
    Sci Adv, 2020-08-12;6(33):eaaz0748.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Oridonin ameliorates inflammation-induced bone loss in mice via suppressing DC-STAMP expression
    Authors: BH Zou, YH Tan, WD Deng, JH Zheng, Q Yang, MH Ke, ZB Ding, XJ Li
    Acta Pharmacol. Sin., 2020-08-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin
    Authors: T Velletri, Y Huang, Y Wang, Q Li, M Hu, N Xie, Q Yang, X Chen, Q Chen, P Shou, Y Gan, E Candi, AP Margherita, M Agostini, H Yang, G Melino, Y Shi, Y Wang
    Cell Death Differ., 2020-07-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  221. Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
    Authors: K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai
    Cell Rep, 2020-07-14;32(2):107906.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-&kappaB signaling downstream of FFAR4
    Authors: Y Tsuchiya, M Hayashi, K Nagamatsu, T Ono, M Kamakura, T Iwata, T Nakashima
    J. Biol. Chem., 2020-07-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  223. Role of microglia in the dissemination of Zika virus from mother to fetal brain
    Authors: P Xu, C Shan, TJ Dunn, X Xie, H Xia, J Gao, J Allende La, J Zou, PP Villarreal, CR Schlagal, Y Yu, G Vargas, SL Rossi, N Vasilakis, PY Shi, SC Weaver, P Wu
    PLoS Negl Trop Dis, 2020-07-06;14(7):e0008413.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  224. Dual role of phosphatidylserine and its receptors in osteoclastogenesis
    Authors: JH Kang, HM Ko, GD Han, SY Lee, JS Moon, MS Kim, JT Koh, SH Kim
    Cell Death Dis, 2020-07-01;11(7):497.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  225. PD-1 blockade inhibits osteoclast formation and murine bone cancer pain
    Authors: K Wang, Y Gu, Y Liao, S Bang, CR Donnelly, O Chen, X Tao, AJ Mirando, MJ Hilton, RR Ji
    J. Clin. Invest., 2020-07-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling-mediated TRAF6 and c-Src recruitment and NF-&kappaB, MAPK and Akt pathways
    Authors: H Chen, C Fang, X Zhi, S Song, Y Gu, X Chen, J Cui, Y Hu, W Weng, Q Zhou, Y Wang, Y Wang, H Jiang, X Li, L Cao, X Chen, J Su
    J. Cell. Mol. Med., 2020-06-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  227. Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-&kappaB signaling pathway
    Authors: M Chen, Y Zhang, P Zhou, X Liu, H Zhao, X Zhou, Q Gu, B Li, X Zhu, Q Shi
    Bioact Mater, 2020-06-30;5(4):880-890.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  228. Water Extract of Lysimachia christinae Inhibits Trabecular Bone Loss and Fat Accumulation in Ovariectomized Mice
    Authors: KS Shim, YH Hwang, SA Jang, T Kim, H Ha
    Nutrients, 2020-06-29;12(7):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  229. Ablation of Gadd45beta ameliorates the inflammation and renal fibrosis caused by unilateral ureteral obstruction
    Authors: SJ Moon, JH Kim, YK Choi, CH Lee, JH Hwang
    J. Cell. Mol. Med., 2020-06-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Progranulin inhibits LPS-induced macrophage M1 polarization via NF-?B and MAPK pathways
    Authors: L Liu, H Guo, A Song, J Huang, Y Zhang, S Jin, S Li, L Zhang, C Yang, P Yang
    BMC Immunol., 2020-06-05;21(1):32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  231. The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo
    Authors: YW Ge, K Feng, XL Liu, HF Chen, ZY Sun, CF Wang, ZQ Liu, HW Wang, JW Zhang, DG Yu, YQ Mao
    Oxid Med Cell Longev, 2020-06-05;2020(0):1404915.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Dendritic cells-derived interferon-lambda1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis
    Authors: Y Chen, Y Wang, R Tang, J Yang, C Dou, Y Dong, D Sun, C Zhang, L Zhang, Y Tang, Q Dai, F Luo, J Xu, S Dong
    Cell Death Dis, 2020-06-02;11(6):414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  233. CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia
    Authors: Z Hu, N Deng, K Liu, N Zhou, Y Sun, W Zeng
    Cell Rep, 2020-05-19;31(7):107657.
    Species: Mouse
    Sample Types:
    Applications: In Vivo
  234. Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade
    Authors: L Zhang, Y Yang, Z Liao, Q Liu, X Lei, M Li, Saijilafu, Z Zhang, D Hong, M Zhu, B Li, H Yang, J Chen
    Theranostics, 2020-05-17;10(15):6638-6660.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  235. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
    Authors: JM Kim, YS Yang, KH Park, X Ge, R Xu, N Li, M Song, H Chun, S Bok, JF Charles, O Filhol-Coc, B Boldyreff, T Dinter, PB Yu, N Kon, W Gu, T Takarada, MB Greenblatt, JH Shim
    Nat Commun, 2020-05-08;11(1):2289.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity
    Authors: Y Huang, H Wang, Y Hao, H Lin, M Dong, J Ye, L Song, Y Wang, Q Li, B Shan, Y Jiang, H Li, Z Shao, G Kroemer, H Zhang, L Bai, T Jin, C Wang, Y Ma, Y Cai, C Ding, S Liu, Y Pan, W Jiang, R Zhou
    Nat. Cell Biol., 2020-05-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains
    Authors: P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma
    Physiol Rep, 2020-05-01;8(9):e14441.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis
    Authors: E van den Bo, B Ambrosy, M Horsthemke, S Walbaum, AC Bachg, N Wettschure, G Innamorati, TM Wilkie, PJ Hanley
    J. Biol. Chem., 2020-04-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Bioassay
  239. Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells
    Authors: JA Carroll, BR Groveman, K Williams, R Moore, B Race, CL Haigh
    Sci Rep, 2020-04-20;10(1):6654.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of Smo in Macrophage/Osteoclast Lineage Prevents Age-Related Bone Loss
    Authors: Y Kohara, R Haraguchi, R Kitazawa, Y Imai, S Kitazawa
    Int J Mol Sci, 2020-04-15;21(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  241. Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model
    Authors: JS Suh, SH Lee, Z Fouladian, JY Lee, T Kim, MK Kang, AJ Lusis, KI Boström, RH Kim, NH Park
    Sci Rep, 2020-04-14;10(1):6383.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Perturbed mitochondrial dynamics is a novel feature of colitis that can be targeted to lessen disease
    Authors: NL Mancini, L Goudie, W Xu, R Sabouny, S Rajeev, A Wang, N Esquerre, A Al Rajabi, TS Jayme, E van Tilbur, Y Nasser, JGP Ferraz, T Shutt, J Shearer, DM McKay
    Cell Mol Gastroenterol Hepatol, 2020-04-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  243. CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/&beta-Catenin Pathway in Osteoporosis
    Authors: W Wu, Z Xiao, Y Chen, Y Deng, D Zeng, Y Liu, F Huang, J Wang, Y Liu, JA Bellanti, L Rong, SG Zheng
    Mol. Ther., 2020-04-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Mycobacterium avium subsp. paratuberculosis MAP1889c Protein Induces Maturation of Dendritic Cells and Drives Th2-biased Immune Responses
    Authors: HS Park, YW Back, YJ Son, HJ Kim
    Cells, 2020-04-11;9(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway
    Authors: C Goda, D Balli, M Black, D Milewski, T Le, V Ustiyan, X Ren, VV Kalinichen, TV Kalin
    PLoS Genet., 2020-04-09;16(4):e1008692.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice
    Authors: MB Uccellini, SV Bardina, MT Sánchez-Ap, KM White, YJ Hou, JK Lim, A García-Sas
    Cell Rep, 2020-04-07;31(1):107498.
    Species: Mouse
    Sample Types: N/A, Whole Cells
    Applications: Bioassay
  247. MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-&kappaB Signaling Pathway
    Authors: H Fan, D Li, X Guan, Y Yang, J Yan, J Shi, R Ma, Q Shu
    Drug Des Devel Ther, 2020-04-05;14(0):1377-1389.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  248. Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-&kappaB and P38 MAPK Signaling Pathways
    Authors: X Hu, Z Yin, X Chen, G Jiang, D Yang, Z Cao, S Li, Z Liu, D Peng, P Dou
    Front Pharmacol, 2020-04-03;11(0):385.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Magnoflorine Suppresses MAPK and NF-&kappaB Signaling to Prevent Inflammatory Osteolysis Induced by Titanium Particles In Vivo and Osteoclastogenesis via RANKL In Vitro
    Authors: Z Sun, J Zeng, W Wang, X Jia, Q Wu, D Yu, Y Mao
    Front Pharmacol, 2020-04-02;11(0):389.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Pregnenolone Inhibits Osteoclast Differentiation and Protects Against Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss
    Authors: X Sun, C Zhang, H Guo, J Chen, Y Tao, F Wang, X Lin, Q Liu, L Su, A Qin
    Front Pharmacol, 2020-03-27;11(0):360.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Differential regulation of breast cancer bone metastasis by PARP1 and PARP2
    Authors: H Zuo, D Yang, Q Yang, H Tang, YX Fu, Y Wan
    Nat Commun, 2020-03-27;11(1):1578.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo
    Authors: K Miyagawa, Y Ohata, J Delgado-Ca, J Teramachi, H Zhou, DW Dempster, MA Subler, JJ Windle, J Chirgwin, GD Roodman, N Kurihara
    JCI Insight, 2020-03-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  253. Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C-Src and inhibiting NF-&kappaB, MAPK and AKT pathways
    Authors: X Zhi, C Fang, Y Gu, H Chen, X Chen, J Cui, Y Hu, W Weng, Q Zhou, Y Wang, Y Wang, H Jiang, X Li, L Cao, X Chen, J Su
    J. Cell. Mol. Med., 2020-03-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  254. F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NF&kappaB signaling pathways
    Authors: Y Zhang, H Wang, G Zhu, A Qian, W Chen
    Int. J. Biol. Sci., 2020-03-12;16(9):1629-1639.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis
    Authors: YR Kim, JS Kim, SJ Gu, S Jo, S Kim, S Young Kim, D Lee, K Jang, H Choo, TH Kim, JU Jung, SJ Min, CS Yang
    Sci Rep, 2020-03-12;10(1):4570.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  256. The Peroxisome Proliferator-Activated Receptor &alpha- Agonist Gemfibrozil Promotes Defense Against Mycobacterium abscessus Infections
    Authors: YS Kim, JK Kim, BTB Hanh, SY Kim, HJ Kim, YJ Kim, SM Jeon, CR Park, GT Oh, JW Park, JM Kim, J Jang, EK Jo
    Cells, 2020-03-06;9(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  257. Osthole-loaded N-octyl-O-sulfonyl chitosan micelles (NSC-OST) inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in rats
    Authors: L Wang, S Zheng, G Huang, J Sun, Y Pan, Y Si, P Tu, G Xu, Y Ma, Y Guo
    J. Cell. Mol. Med., 2020-03-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  258. Transient Inhibition of PI3K&delta Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus
    Authors: MS Ferguson, LS Chard Dunm, R Gangeswara, G Marelli, JR Tysome, E Burns, MA Whitehead, E Aksoy, G Alusi, C Hiley, J Ahmed, B Vanhaesebr, NR Lemoine, Y Wang
    Mol. Ther., 2020-02-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  259. NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis
    Authors: H Liu, Y Zhu, Y Gao, D Qi, L Zhao, L Zhao, C Liu, T Tao, C Zhou, X Sun, F Guo, J Xiao
    Cell Death Dis, 2020-02-18;11(2):129.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  260. Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities
    Authors: S Ikezu, H Yeh, JC Delpech, ME Woodbury, AA Van Enoo, Z Ruan, S Sivakumara, Y You, C Holland, T Guillamon-, A Yoshii-Kit, MB Botros, C Madore, PH Chao, A Desani, S Manimaran, SV Kalavai, WE Johnson, O Butovsky, M Medalla, JI Luebke, T Ikezu
    Mol. Psychiatry, 2020-02-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury
    Authors: FQ Kong, SJ Zhao, P Sun, H Liu, J Jie, T Xu, AD Xu, YQ Yang, Y Zhu, J Chen, Z Zhou, DF Qian, CJ Gu, Q Chen, GY Yin, HW Zhang, J Fan
    J Neuroinflammation, 2020-02-17;17(1):62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  262. Regulation of bone metabolism by megakaryocytes in a paracrine manner
    Authors: YS Lee, MK Kwak, SA Moon, YJ Choi, JE Baek, SY Park, BJ Kim, SH Lee, JM Koh
    Sci Rep, 2020-02-10;10(1):2277.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Environmental arginine controls multinuclear giant cell metabolism and formation
    Authors: JS Brunner, L Vulliard, M Hofmann, M Kieler, A Lercher, A Vogel, M Russier, JB Brüggenthi, M Kerndl, V Saferding, B Niederreit, A Junza, A Frauenstei, C Scholtysek, Y Mikami, K Klavins, G Krönke, A Bergthaler, JJ O'Shea, T Weichhart, F Meissner, JS Smolen, P Cheng, O Yanes, J Menche, PJ Murray, O Sharif, S Blüml, G Schabbauer
    Nat Commun, 2020-01-22;11(1):431.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  264. Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
    Authors: JR Plemel, JA Stratton, NJ Michaels, KS Rawji, E Zhang, S Sinha, CS Baaklini, Y Dong, M Ho, K Thorburn, TN Friedman, S Jawad, C Silva, AV Caprariell, V Hoghooghi, J Yue, A Jaffer, K Lee, BJ Kerr, R Midha, PK Stys, J Biernaskie, VW Yong
    Sci Adv, 2020-01-15;6(3):eaay6324.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Cell Culture
  265. Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation
    Authors: RK Arya, R Goswami, SO Rahaman
    The Journal of Biological Chemistry, 2020-01-01;296(0):100129.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL
    Authors: DHH Molstad, AM Mattson, DL Begun, JJ Westendorf, EW Bradley
    J Biol Chem, 2020-01-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Pharmacological Properties of JTE-952, an Orally Available and Selective Colony Stimulating Factor 1 Receptor Kinase Inhibitor
    Authors: N Uesato, N Miyagawa, K Inagaki, R Kakefuda, Y Kitagawa, Y Matsuo, T Yamaguchi, T Hata, K Ikegashira, M Matsushita
    Biol. Pharm. Bull., 2020-01-01;43(2):325-333.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  268. Inhibitory effects of dabigatran etexilate, a direct thrombin inhibitor, on osteoclasts and osteoblasts
    Authors: AL Rocha, RL Bighetti-T, LF Duffles, JAA de Arruda, TM Taira, BRD Assis, S Macari, IMA Diniz, MM Beloti, AL Rosa, SY Fukada, GAC Goulart, DD Ribeiro, LG Abreu, TA Silva
    Thromb. Res., 2019-12-23;186(0):45-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Gas6/MerTK signaling is negatively regulated by NF-&kappaB and supports lung carcinogenesis
    Authors: SV Novitskiy, R Zaynagetdi, G Vasiukov, S Gutor, W Han, A Serezani, A Matafonov, LA Gleaves, TP Sherrill, VV Polosukhin, TS Blackwell
    Oncotarget, 2019-12-17;10(66):7031-7042.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-kappaB and CD9/gp130/STAT3 signalling pathway
    Authors: J Hu, X Li, Y Chen, X Han, L Li, Z Yang, L Duan, H Lu, Q He
    J. Cell. Mol. Med., 2019-12-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Interleukin-27 Is Essential for Type 1 Diabetes Development and Sj�gren Syndrome-like Inflammation
    Authors: AE Ciecko, B Foda, JY Barr, S Ramanathan, MA Atkinson, DV Serreze, AM Geurts, SM Lieberman, YG Chen
    Cell Rep, 2019-12-03;29(10):3073-3086.e5.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Tissue Culture
  272. P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation
    Authors: J Nagai, B Balestrier, LB Fanning, T Kyin, H Cirka, J Lin, M Idzko, A Zech, EY Kim, PJ Brennan, JA Boyce
    J. Clin. Invest., 2019-12-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  273. A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption
    Authors: SK Pore, ER Hahm, SH Kim, KB Singh, L Nyiranshut, JD Latoche, CJ Anderson, J Adamik, DL Galson, KR Weiss, RJ Watters, B Lee, PN Kumta, SV Singh
    Mol. Cancer Ther., 2019-11-29;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Diterpenoids from the aerial parts of Flueggea acicularis and their activity against RANKL-induced osteoclastogenesis
    Authors: D Huang, X Luo, Z Yin, J Xu, Q Gu
    Bioorg. Chem., 2019-11-23;0(0):103453.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  275. Mitofusin 2-Deficiency Suppresses Mycobacterium tuberculosis Survival in Macrophages
    Authors: J Lee, JA Choi, SN Cho, SH Son, CH Song
    Cells, 2019-10-30;8(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  276. Phillyrin Attenuates Osteoclast Formation and Function and Prevents LPS-Induced Osteolysis in Mice
    Authors: J Wang, G Chen, Q Zhang, F Zhao, X Yu, X Ma, M Liu
    Front Pharmacol, 2019-10-17;10(0):1188.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. MicroRNA-29a Counteracts Glucocorticoid Induction of Bone Loss through Repressing TNFSF13b Modulation of Osteoclastogenesis
    Authors: RW Wu, WS Lian, YS Chen, CW Kuo, HC Ke, CK Hsieh, SY Wang, JY Ko, FS Wang
    Int J Mol Sci, 2019-10-17;20(20):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Cell Culture
  278. PRMT6 promotes lung tumor progression via the alternate activation of tumor-associated macrophages
    Authors: S Avasarala, PY Wu, SQ Khan, S Yanlin, M Van Scoyk, J Bao, A Di Lorenzo, O David, MT Bedford, V Gupta, RA Winn, RK Bikkavilli
    Mol. Cancer Res., 2019-10-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  279. The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation
    Authors: N Wu, XN Nguyen, L Wang, R Appourchau, C Zhang, B Panthu, H Gruffat, C Journo, S Alais, J Qin, N Zhang, K Tartour, F Catez, R Mahieux, T Ohlmann, M Liu, B Du, A Cimarelli
    PLoS Pathog., 2019-10-10;15(10):e1008093.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Lycorine Attenuates Autophagy in Osteoclasts via an Axis of mROS/TRPML1/TFEB to Reduce LPS-Induced Bone Loss
    Authors: HJ Park, M Gholam-Zad, JH Suh, HS Choi
    Oxid Med Cell Longev, 2019-10-08;2019(0):8982147.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  281. Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis
    Authors: Y Wang, J Xie, Z Ai, J Su
    Int J Nanomedicine, 2019-09-26;14(0):7839-7849.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  282. MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12
    Authors: WS Lian, JY Ko, YS Chen, HJ Ke, CK Hsieh, CW Kuo, SY Wang, BW Huang, JG Tseng, FS Wang
    Cell Death Dis, 2019-09-23;10(10):705.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Cathepsin L secretion by host and neoplastic cells potentiates invasion
    Authors: SS Dykes, HO Fasanya, DW Siemann
    Oncotarget, 2019-09-17;10(53):5560-5568.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Cleavage of RIPK1 by caspase-8�is crucial for limiting apoptosis and necroptosis
    Authors: K Newton, KE Wickliffe, DL Dugger, A Maltzman, M Roose-Girm, M Dohse, L K?m?ves, JD Webster, VM Dixit
    Nature, 2019-09-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Development of bone seeker-functionalised microspheres as a targeted local antibiotic delivery system for bone infections
    Authors: SG Rotman, K Thompson, DW Grijpma, RG Richards, TF Moriarty, D Eglin, O Guillaume
    J Orthop Translat, 2019-08-30;21(0):136-145.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-?b signaling
    Authors: X Sun, Z Xie, B Hu, B Zhang, Y Ma, X Pan, H Huang, J Wang, X Zhao, Z Jie, P Shi, Z Chen
    Redox Biol, 2019-08-27;28(0):101309.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
    Authors: A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies
    Br. J. Cancer, 2019-08-16;121(7):556-566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Stachydrine prevents LPS-induced bone loss by inhibiting osteoclastogenesis via NF-κB and Akt signalling
    Authors: J Meng, C Zhou, W Zhang, W Wang, B He, B Hu, G Jiang, Y Wang, J Hong, S Li, J He, S Yan, W Yan
    J. Cell. Mol. Med., 2019-07-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  289. Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome
    Authors: L Sun, W Ma, W Gao, Y Xing, L Chen, Z Xia, Z Zhang, Z Dai
    Cell Death Dis, 2019-07-17;10(8):542.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation
    Authors: D Xiong, L Song, S Geng, Y Jiao, X Zhou, H Song, X Kang, Y Zhou, X Xu, J Sun, Z Pan, X Jiao
    Cell Rep, 2019-07-16;28(3):804-818.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis
    Authors: YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim
    Nat Commun, 2019-07-04;10(1):2958.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  292. Adult stem cell deficits drive Slc29a3 disorders in mice
    Authors: S Nair, AM Strohecker, AK Persaud, B Bissa, S Muruganand, C McElroy, R Pathak, M Williams, R Raj, A Kaddoumi, A Sparreboom, AM Beedle, R Govindaraj
    Nat Commun, 2019-07-03;10(1):2943.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  293. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
    Authors: SS Welc, I Flores, M Wehling-He, J Ramos, Y Wang, C Bertoni, JG Tidball
    Nat Commun, 2019-06-26;10(1):2788.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Sfrp4 repression of the Ror2/Jnk cascade in osteoclasts protects cortical bone from excessive endosteal resorption
    Authors: K Chen, PY Ng, R Chen, D Hu, S Berry, R Baron, F Gori
    Proc. Natl. Acad. Sci. U.S.A., 2019-06-25;0(0):.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Dehydrocostus lactone attenuates osteoclastogenesis and osteoclast-induced bone loss by modulating NF-?B signalling pathway
    Authors: B Hu, F Wu, Z Shi, B He, X Zhao, H Wu, S Yan
    J. Cell. Mol. Med., 2019-06-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Rab32 GTPase, as a direct target of miR-30b/c, controls the intracellular survival of Burkholderia pseudomallei by regulating phagosome maturation
    Authors: ZQ Hu, CL Rao, ML Tang, Y Zhang, XX Lu, JG Chen, C Mao, L Deng, Q Li, XH Mao
    PLoS Pathog., 2019-06-14;15(6):e1007879.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice
    Authors: AM Mattson, DL Begun, DHH Molstad, MA Meyer, MJ Oursler, JJ Westendorf, EW Bradley
    J. Biol. Chem., 2019-06-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors
    Authors: J Gilmour, L O'Connor, CP Middleton, P Keane, N Gillemans, JB Cazier, S Philipsen, C Bonifer
    Epigenetics Chromatin, 2019-06-04;12(1):33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Nerve modulation therapy in gouty arthritis: targeting increased sFRP2 expression in dorsal root ganglion regulates macrophage polarization and alleviates endothelial damage
    Authors: J Mei, F Zhou, H Qiao, H Li, T Tang
    Theranostics, 2019-05-31;9(13):3707-3722.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  300. Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization
    Authors: CP Hans, N Sharma, S Sen, S Zeng, R Dev, Y Jiang, A Mahajan, T Joshi
    Sci Rep, 2019-05-29;9(1):7999.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice
    Authors: S Marino, D de Ridder, RT Bishop, N Renema, M Ponzetti, A Sophocleou, M Capulli, A Aljeffery, G Carrasco, MD Gens, A Khogeer, SH Ralston, J Gertsch, F Lamoureux, D Heymann, N Rucci, AI Idris
    EBioMedicine, 2019-05-29;44(0):452-466.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression
    Authors: S Lotinun, Y Ishihara, K Nagano, R Kiviranta, V Carpentier, L Neff, V Parkman, N Ide, D Hu, P Dann, D Brooks, ML Bouxsein, J Wysolmersk, F Gori, R Baron
    J. Clin. Invest., 2019-05-21;130(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  303. Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury
    Authors: LL Lv, Y Feng, M Wu, B Wang, ZL Li, X Zhong, WJ Wu, J Chen, HF Ni, TT Tang, RN Tang, HY Lan, BC Liu
    Cell Death Differ., 2019-05-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget's disease
    Authors: SW Wong, BW Huang, X Hu, E Ho Kim, JP Kolb, RJ Padilla, P Xue, L Wang, TH Oguin, PA Miguez, HC Tseng, CC Ko, J Martinez
    Cell Death Differ., 2019-05-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Caspase-1 initiates apoptosis in the absence of gasdermin D
    Authors: K Tsuchiya, S Nakajima, S Hosojima, D Thi Nguyen, T Hattori, T Manh Le, O Hori, MR Mahib, Y Yamaguchi, M Miura, T Kinoshita, H Kushiyama, M Sakurai, T Shiroishi, T Suda
    Nat Commun, 2019-05-07;10(1):2091.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  306. Tumor derived EDIL3 modulates the expansion and osteoclastogenesis of myeloid derived suppressor cells in murine breast cancer model
    Authors: Z Kun, G Xin, W Tao, Z Chenglong, W Dongsheng, T Liang, L Tielong, X Jianru
    J Bone Oncol, 2019-04-29;16(0):100238.
    Species: Mouse
    Sample Types: Tumor Cells
    Applications: Bioassay
  307. A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice
    Authors: HK Kwon, MC Patra, HJ Shin, X Gui, A Achek, S Panneersel, DJ Kim, SJ Song, R Hong, KS Kim, YG Kim, FY Lee, DH Hahm, SH Lee, S Choi
    Exp. Mol. Med., 2019-04-26;51(4):50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  308. MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis
    Authors: NE Putnam, LE Fulbright, JM Curry, CA Ford, JR Petronglo, AS Hendrix, JE Cassat
    PLoS Pathog., 2019-04-12;15(4):e1007744.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Discovery of new inhibitors against both NF-?B and osteoclastogenesis from in-house library with ?, ?-unsaturated-enone fragment
    Authors: C Zhao, D Huang, R Li, J Xu, Q Gu, J Xu
    Bioorg. Chem., 2019-03-28;87(0):638-646.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. PI3K activation increases SDF-1 production and number of osteoclast precursors, and enhances SDF-1-mediated osteoclast precursor migration
    Authors: NS Adapala, S Root, J Lorenzo, H Aguila, A Sanjay
    Bone Rep, 2019-03-22;10(0):100203.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  311. The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4
    Authors: N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup
    Sci Rep, 2019-03-14;9(1):4515.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  312. Rg6, a rare ginsenoside, inhibits systemic inflammation through the induction of interleukin-10 and microRNA-146a
    Authors: S Paik, JH Choe, GE Choi, JE Kim, JM Kim, GY Song, EK Jo
    Sci Rep, 2019-03-13;9(1):4342.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential
    Authors: HS Park, YW Back, KW Shin, HS Bae, KI Lee, HG Choi, S Choi, HH Lee, CH Choi, JK Park, HJ Kim
    Sci Rep, 2019-03-12;9(1):4246.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Characterisation of genes differentially expressed in macrophages by virulent and attenuated Mycobacterium tuberculosis through RNA-Seq analysis
    Authors: J Lee, SG Lee, KK Kim, YJ Lim, JA Choi, SN Cho, C Park, CH Song
    Sci Rep, 2019-03-11;9(1):4027.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis
    Authors: P Handa, S Thomas, V Morgan-Ste, BD Maliken, E Gochanour, S Boukhar, MM Yeh, KV Kowdley
    J. Leukoc. Biol., 2019-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
    Authors: J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen
    Nat. Med., 2019-03-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  317. SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions
    Authors: TS Kim, YB Jin, YS Kim, S Kim, JK Kim, HM Lee, HW Suh, JH Choe, YJ Kim, BS Koo, HN Kim, M Jung, SH Lee, DK Kim, C Chung, JW Son, JJ Min, JM Kim, CX Deng, HS Kim, SR Lee, EK Jo
    Autophagy, 2019-03-04;0(0):20-Jan.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
    Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
    Nat Microbiol, 2019-02-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury
    Authors: H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu
    JCI Insight, 2019-02-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Fasciola hepatica GST downregulates NF-?B pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model
    Authors: V Aguayo, BN Valdés Fer, M Rodríguez-, C Ruiz-Jimén, MJ Ramos-Bení, LB Méndez, AM Espino
    Sci Rep, 2019-02-19;9(1):2275.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways
    Authors: X Rao, S Zhao, Z Braunstein, H Mao, M Razavi, L Duan, Y Wei, AC Toomey, S Rajagopala, J Zhong
    EBioMedicine, 2019-02-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  322. CD200 Modulates S. aureus-Induced Innate Immune Responses Through Suppressing p38 Signaling
    Authors: B Zhu, Y Yu, X Liu, Q Han, Y Kang, L Shi
    Int J Mol Sci, 2019-02-03;20(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  323. A potential therapeutic target for regulating osteoporosis via suppression of osteoclast differentiation
    Authors: Q Sun, B Zhang, W Zhu, W Wei, J Ma, FR Tay
    J Dent, 2019-02-01;0(0):.
    Species: Mouse
    Sample Types:
    Applications: Bioassay
  324. Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82
    Authors: A Bergsma, SS Ganguly, ME Wiegand, D Dick, BO Williams, CK Miranti
    Bone Rep, 2019-01-30;10(0):100196.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  325. L-caldesmon alters cell spreading and adhesion force in RANKL-induced osteoclasts
    Authors: CL Chan, JY Chen, MC Shih, CA Wang, YM Liou
    J. Biomed. Sci., 2019-01-24;26(1):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  326. The neurosteroid, pregnenolone promotes degradation of key proteins in the innate immune signalling to suppress inflammation
    Authors: S Murugan, P Jakka, S Namani, V Mujumdar, G Radhakrish
    J. Biol. Chem., 2019-01-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
    Authors: R Singh, S Chandrashe, SR Bodduluri, BV Baby, B Hegde, NG Kotla, AA Hiwale, T Saiyed, P Patel, M Vijay-Kuma, MGI Langille, GM Douglas, X Cheng, EC Rouchka, SJ Waigel, GW Dryden, H Alatassi, HG Zhang, B Haribabu, PK Vemula, VR Jala
    Nat Commun, 2019-01-09;10(1):89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  328. ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes
    Authors: MB Uccellini, A García-Sas
    Cell Rep, 2018-12-04;25(10):2784-2796.e3.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Induction of Kr�ppel-like factor 2 reduces K/BxN serum-induced arthritis
    Authors: M Das, D Laha, S Kanji, M Joseph, R Aggarwal, OH Iwenofu, VJ Pompili, MK Jain, H Das
    J. Cell. Mol. Med., 2018-12-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Skeletal phenotype of the neuropeptide Y knockout mouse
    Authors: NKY Wee, BP Sinder, S Novak, X Wang, C Stoddard, BG Matthews, I Kalajzic
    Neuropeptides, 2018-11-30;73(0):78-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Protective effects of a traditional herbal extract from Stellaria dichotoma var. lanceolata against Mycobacterium abscessus infections
    Authors: SJ Bae, JW Choi, BJ Park, J Lee, EK Jo, YH Lee, SB Kim, JM Yuk
    PLoS ONE, 2018-11-19;13(11):e0207696.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice
    Authors: H Jin, L Yao, K Chen, Y Liu, Q Wang, Z Wang, Q Liu, Z Cao, J Kenny, J Tickner, X Wang, J Xu
    J. Cell. Mol. Med., 2018-11-19;23(1):522-534.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Inhibition of STAT5A promotes osteogenesis by DLX5 regulation
    Authors: KM Lee, KH Park, JS Hwang, M Lee, DS Yoon, HA Ryu, HS Jung, KW Park, J Kim, SW Park, SH Kim, YM Chun, WJ Choi, JW Lee
    Cell Death Dis, 2018-11-14;9(11):1136.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  334. HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
    Authors: AN Billin, SE Honeycutt, AV McDougal, JP Kerr, Z Chen, JM Freudenber, DK Rajpal, G Luo, HF Kramer, RS Geske, F Fang, B Yao, RV Clark, J Lepore, A Cobitz, R Miller, K Nosaka, AC Hinken, AJ Russell
    Skelet Muscle, 2018-11-13;8(1):35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival
    Authors: K Subramania, DR Neill, HA Malak, L Spelmink, S Khandaker, G Dalla Libe, E Dearing, A Kirby, M Yang, A Achour, J Nilvebrant, PÅ Nygren, L Plant, A Kadioglu, B Henriques-
    Nat Microbiol, 2018-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer
    Authors: J Zhou, X Li, X Wu, T Zhang, Q Zhu, X Wang, H Wang, K Wang, Y Lin, X Wang
    Cancer Immunol Res, 2018-11-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression
    Authors: MN Lee, HS Hwang, SH Oh, A Roshanzade, JW Kim, JH Song, ES Kim, JT Koh
    Exp. Mol. Med., 2018-11-05;50(11):142.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  338. An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages
    Authors: V Beneke, F Küster, AL Neehus, C Hesse, E Lopez-Rodr, K Haake, A Rafiei Has, JW Schott, D Walter, A Braun, WF Wolkers, M Ackermann, N Lachmann
    Sci Rep, 2018-11-02;8(1):16281.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  339. Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice
    Authors: T Hara, PT Phuong, D Fukuda, K Yamaguchi, C Murata, S Nishimoto, S Yagi, K Kusunose, H Yamada, T Soeki, T Wakatsuki, I Imoto, M Shimabukur, M Sata
    Circulation, 2018-10-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  340. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
    Authors: JK Kim, YS Kim, HM Lee, HS Jin, C Neupane, S Kim, SH Lee, JJ Min, M Sasai, JH Jeong, SK Choe, JM Kim, M Yamamoto, HE Choy, JB Park, EK Jo
    Nat Commun, 2018-10-10;9(1):4184.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Bone marrow mesenchymal stem cells tune the differentiation of myeloid-derived suppressor cells in bleomycin-induced lung injury
    Authors: X Su, L Yang, Y Yin, J Huang, F Qiao, Y Fang, L Yu, Y Wang, K Zhou, J Wang
    Stem Cell Res Ther, 2018-09-26;9(1):253.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  342. Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation
    Authors: J Meng, C Zhou, B Hu, M Luo, Y Yang, Y Wang, W Wang, G Jiang, J Hong, S Li, H Wu, S Yan, W Yan
    Front Pharmacol, 2018-09-26;9(0):1053.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
    Authors: E Mobarak, L Håversen, M Manna, M Rutberg, M Levin, R Perkins, T Rog, I Vattulaine, J Borén
    Sci Rep, 2018-09-11;8(1):13600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Artemisinin-Daumone Hybrid Inhibits Cancer Cell-Mediated Osteolysis by Targeting Cancer Cells and Osteoclasts
    Authors: GT Ma, SK Lee, KK Park, J Park, SH Son, M Jung, WY Chung
    Cell. Physiol. Biochem., 2018-09-11;49(4):1460-1475.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  345. The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans
    Authors: X Xiang, TM Piers, B Wefers, K Zhu, A Mallach, B Brunner, G Kleinberge, W Song, M Colonna, J Herms, W Wurst, JM Pocock, C Haass
    Mol Neurodegener, 2018-09-06;13(1):49.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Coupling of bone resorption and formation by RANKL reverse signalling
    Authors: Y Ikebuchi, S Aoki, M Honma, M Hayashi, Y Sugamori, M Khan, Y Kariya, G Kato, Y Tabata, JM Penninger, N Udagawa, K Aoki, H Suzuki
    Nature, 2018-09-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  347. Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of ?-amyloid
    Authors: A Rubio-Arai, OM Finucane, S Keogh, MA Lynch
    J Neuroinflammation, 2018-08-31;15(1):247.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPAR? and M2 polarization
    Authors: X Yi, J Zhang, R Zhuang, S Wang, S Cheng, D Zhang, J Xie, W Hu, X Liu, Y Zhang, Y Ding, Y Zhang
    Cytokine, 2018-08-31;111(0):194-205.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  349. A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and ?v?3 integrin for osteoporosis therapy
    Authors: Y Zur, L Rosenfeld, CA Keshelman, N Dalal, G Guterman-R, A Orenbuch, Y Einav, N Levaot, N Papo
    PLoS Biol., 2018-08-24;16(8):e2002979.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Effects of metal ions on caspase-1 activation and interleukin-1? release in murine bone marrow-derived macrophages
    Authors: MA Ferko, I Catelas
    PLoS ONE, 2018-08-23;13(8):e0199936.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model
    Authors: G Locatelli, D Theodorou, A Kendirli, MJC Jordão, O Staszewski, K Phulphagar, L Cantuti-Ca, A Dagkalis, A Bessis, M Simons, F Meissner, M Prinz, M Kerschenst
    Nat. Neurosci., 2018-08-20;21(9):1196-1208.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis
    Authors: C McCarthy, E Lee, JP Bridges, A Sallese, T Suzuki, JC Woods, BJ Bartholmai, T Wang, C Chalk, BC Carey, P Arumugam, K Shima, EJ Tarling, BC Trapnell
    Nat Commun, 2018-08-07;9(1):3127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  353. Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer
    Authors: JM Ubellacker, N Baryawno, N Severe, MJ DeCristo, J Sceneay, JN Hutchinson, MT Haider, CS Rhee, Y Qin, WM Gregory, AC Garrido-Ca, I Holen, JE Brown, RE Coleman, DT Scadden, SS McAllister
    Cancer Res., 2018-07-31;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  354. Inflammatory response of microglia to prions is controlled by sialylation of PrPSc
    Authors: S Srivastava, E Katorcha, N Makarava, JP Barrett, DJ Loane, IV Baskakov
    Sci Rep, 2018-07-27;8(1):11326.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  355. In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-?B Ligand (RANKL)
    Authors: G Melagraki, E Ntougkos, D Papadopoul, V Rinotas, G Leonis, E Douni, A Afantitis, G Kollias
    Front Pharmacol, 2018-07-25;9(0):800.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice
    Authors: Y Yin, H Hao, Y Cheng, L Zang, J Liu, J Gao, J Xue, Z Xie, Q Zhang, W Han, Y Mu
    Cell Death Dis, 2018-07-09;9(7):760.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation
    Authors: MGA Broeren, I Di Ceglie, MB Bennink, PLEM van Lent, WB van den Be, MI Koenders, EN Blaney Dav, PM van der Kr, FAJ van de Loo
    PeerJ, 2018-05-30;6(0):e4771.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  358. SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages
    Authors: Y Hu, F Song, H Jiang, G Nuñez, DE Smith
    J. Immunol., 2018-05-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  359. CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22
    Authors: HJ Koh, YR Kim, JS Kim, JS Yun, S Kim, SY Kim, K Jang, CS Yang
    Exp. Mol. Med., 2018-05-14;50(5):62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Fc? receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis
    Authors: I Di Ceglie, G Ascone, NAJ Cremers, AW Sloetjes, B Walgreen, T Vogl, J Roth, JS Verbeek, FAJ van de Loo, MI Koenders, PM van der Kr, AB Blom, MHJ van den Bo, PLEM van Lent
    Arthritis Res. Ther., 2018-05-02;20(1):80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  361. Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
    Authors: S Kinsella, M Fichtner, O Watters, HG König, JHM Prehn
    J Neuroinflammation, 2018-05-02;15(1):130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach
    Authors: R Berndt, L Hummitzsch, K He beta, M Albrecht, K Zitta, R Rusch, B Sarras, A Bayer, J Cremer, F Faendrich, J Gro beta
    Stem Cell Res Ther, 2018-04-27;9(1):117.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  363. Neogambogic Acid Suppresses Receptor Activator of Nuclear Factor ?B Ligand (RANKL)-Induced Osteoclastogenesis by Inhibiting the JNK and NF-?B Pathways in Mouse Bone Marrow-Derived Monocyte/Macrophages
    Authors: G Jin, FF Wang, T Li, DD Jia, Y Shen, HC Xu
    Med. Sci. Monit., 2018-04-26;24(0):2569-2577.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  364. Reduced oxidative capacity in macrophages results in systemic insulin resistance
    Authors: SB Jung, MJ Choi, D Ryu, HS Yi, SE Lee, JY Chang, HK Chung, YK Kim, SG Kang, JH Lee, KS Kim, HJ Kim, CS Kim, CH Lee, RW Williams, H Kim, HK Lee, J Auwerx, M Shong
    Nat Commun, 2018-04-19;9(1):1551.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  365. Poria cocos polysaccharide attenuates RANKL-induced osteoclastogenesis by suppressing NFATc1 activity and phosphorylation of ERK and STAT3
    Authors: D Song, Z Cao, J Tickner, H Qiu, C Wang, K Chen, Z Wang, C Guo, S Dong, J Xu
    Arch. Biochem. Biophys., 2018-04-17;647(0):76-83.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Cell Culture
  366. Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models
    Authors: CEJ Waterborg, S Beermann, MGA Broeren, MB Bennink, MI Koenders, PLEM van Lent, WB van den Be, PM van der Kr, FAJ van de Loo
    Front Immunol, 2018-04-13;9(0):742.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  367. LncRNA-AK131850 Sponges MiR-93-5p in Newborn and Mature Osteoclasts to Enhance the Secretion of Vascular Endothelial Growth Factor a Promoting Vasculogenesis of Endothelial Progenitor Cells
    Authors: H Quan, M Liang, N Li, C Dou, C Liu, Y Bai, W Luo, J Li, F Kang, Z Cao, X Yang, H Jiang, S Dong
    Cell. Physiol. Biochem., 2018-03-23;46(1):401-417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  368. IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages
    Authors: H Cui, S Banerjee, S Guo, N Xie, G Liu
    J. Immunol., 2018-03-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  369. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018-03-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo
    Authors: E Yoshida, T Suzuki, M Morita, K Taguchi, K Tsuchida, H Motohashi, M Doita, M Yamamoto
    Genes Cells, 2018-03-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
    Authors: M Datta, O Staszewski, E Raschi, M Frosch, N Hagemeyer, TL Tay, T Blank, M Kreutzfeld, D Merkler, S Ziegler-Wa, P Matthias, M Meyer-Lueh, M Prinz
    Immunity, 2018-03-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  372. Fraxinellone Attenuates Rheumatoid Inflammation in Mice
    Authors: SM Jung, J Lee, SY Baek, J Lee, SG Jang, SM Hong, JS Park, ML Cho, SH Park, SK Kwok
    Int J Mol Sci, 2018-03-13;19(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  373. OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9
    Authors: T Ishii, M Ruiz-Torru, A Ikeda, S Shindo, A Movila, H Mawardi, A Albassam, RA Kayal, AA Al-Dharrab, K Egashira, W Wisitrasam, K Yamamoto, AI Mira, K Sueishi, X Han, MA Taubman, T Miyamoto, T Kawai
    FASEB J., 2018-03-13;0(0):fj201701424R.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  374. PGC1? Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation
    Authors: Y Zhang, N Rohatgi, DJ Veis, J Schilling, SL Teitelbaum, W Zou
    J. Bone Miner. Res., 2018-03-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  375. RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
    Authors: C Sun, SY Chen
    J. Immunol., 2018-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  376. The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair
    Authors: D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi
    Front Immunol, 2018-03-05;9(0):417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  377. TNF-?-mediated ER stress causes elimination of Mycobacterium fortuitum reservoirs by macrophage apoptosis
    Authors: SM Oh, YJ Lim, JA Choi, J Lee, SN Cho, D Go, SH Kim, CH Song
    FASEB J., 2018-02-26;0(0):fj201701407R.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2
    Authors: M Langer, AW Girton, NI Popescu, T Burgett, JP Metcalf, KM Coggeshall
    PLoS ONE, 2018-02-23;13(2):e0193207.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia
    Authors: SA O'Sullivan, C O'Sullivan, LM Healy, KK Dev, GK Sheridan
    J. Neurochem., 2018-02-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Monomeric C-Reactive Protein Binds and Neutralizes Receptor Activator of NF-?B Ligand-Induced Osteoclast Differentiation
    Authors: ZK Jia, HY Li, YL Liang, LA Potempa, SR Ji, Y Wu
    Front Immunol, 2018-02-19;9(0):234.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  381. Adenosine Areceptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis
    Authors: A Mediero, T Wilder, L Shah, BN Cronstein
    FASEB J., 2018-02-02;0(0):fj201700217R.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  382. Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice
    Authors: Y Ito, N Schaefer, A Sanchez, D Francisco, R Alam, RJ Martin, JG Ledford, C Stevenson, D Jiang, L Li, M Kraft, HW Chu
    J Innate Immun, 2018-01-27;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  383. High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
    Authors: A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai
    Front Immunol, 2018-01-18;9(0):22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  384. Targeted disruption of adenosine kinase in myeloid monocyte cells increases osteoclastogenesis and bone resorption in mice
    Authors: Q Ye, G Li, S Liu, Y Guan, Y Li, J Li, H Jia, X Li, Q Li, R Huang, H Wang, Y Zhang
    Int. J. Mol. Med., 2018-01-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  385. Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
    Authors: S Lucas, Y Omata, J Hofmann, M Böttcher, A Iljazovic, K Sarter, O Albrecht, O Schulz, B Krishnacou, G Krönke, M Herrmann, D Mougiakako, T Strowig, G Schett, MM Zaiss
    Nat Commun, 2018-01-04;9(1):55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  386. A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects
    Authors: JE Draper, P Sroczynska, MZH Fadlullah, R Patel, G Newton, W Breitwiese, V Kouskoff, G Lacaud
    PLoS Genet., 2018-01-04;14(1):e1007127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  387. Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice
    Authors: D Quach, F Collins, N Parameswar, L McCabe, RA Britton
    mSphere, 2018-01-03;3(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  388. STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis
    Authors: J Ahn, S Son, SC Oliveira, GN Barber
    Cell Rep, 2017-12-26;21(13):3873-3884.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  389. The HIV co-receptor CCR5 regulates osteoclast function
    Authors: JW Lee, A Hoshino, K Inoue, T Saitou, S Uehara, Y Kobayashi, S Ueha, K Matsushima, A Yamaguchi, Y Imai, T Iimura
    Nat Commun, 2017-12-20;8(1):2226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis
    Authors: EM Grössinger, M Kang, L Bouchareyc, R Sarin, DR Haudenschi, LN Borodinsky, IE Adamopoulo
    J. Immunol., 2017-12-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Metformin Mediates Protection against Legionella Pneumonia through Activation of AMPK and Mitochondrial Reactive Oxygen Species
    Authors: C Kajiwara, Y Kusaka, S Kimura, T Yamaguchi, Y Nanjo, Y Ishii, H Udono, TJ Standiford, K Tateda
    J. Immunol., 2017-12-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  392. MiR-30a attenuates osteoclastogenesis via targeting DC-STAMP-c-Fos-NFATc1 signaling
    Authors: Y Yin, L Tang, J Chen, X Lu
    Am J Transl Res, 2017-12-15;9(12):5743-5753.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Systemic administration of ?-glucan of 200�kDa modulates melanoma microenvironment and suppresses metastatic cancer
    Authors: M Zhang, L Chun, V Sandoval, H Graor, J Myers, J Nthale, P Rauhe, Z Senders, K Choong, AY Huang, J Kim
    Oncoimmunology, 2017-10-30;7(2):e1387347.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  394. Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons
    Authors: L Parviainen, S Dihanich, GW Anderson, AM Wong, HR Brooks, R Abeti, P Rezaie, G Lalli, S Pope, SJ Heales, HM Mitchison, BP Williams, JD Cooper
    Acta Neuropathol Commun, 2017-10-17;5(1):74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  395. Pharmacological HIF-inhibition attenuates postoperative adhesion formation
    Authors: MJ Strowitzki, AS Ritter, P Radhakrish, JM Harnoss, VM Opitz, M Biller, J Wehrmann, U Keppler, J Scheer, M Wallwiener, T Schmidt, A Ulrich, M Schneider
    Sci Rep, 2017-10-13;7(1):13151.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  396. Small leucine rich proteoglycans, a novel link to osteoclastogenesis
    Authors: V Kram, TM Kilts, N Bhattachar, L Li, MF Young
    Sci Rep, 2017-10-03;7(1):12627.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  397. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response
    Authors: BF Westendorp, NVJA Büller, ON Karpus, WA van Dop, J Koster, R Versteeg, PJ Koelink, CY Snel, S Meisner, JJTH Roelofs, A Uhmann, E Ver Loren, J Heijmans, H Hahn, V Muncan, ME Wildenberg, GR van den Br
    Cell Mol Gastroenterol Hepatol, 2017-09-05;5(1):67-82.e1.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  398. ESRRA (estrogen related receptor, alpha) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense
    Authors: SY Kim, CS Yang, HM Lee, JK Kim, YS Kim, YR Kim, JS Kim, TS Kim, JM Yuk, CR Dufour, SH Lee, JM Kim, HS Choi, V Giguère, EK Jo
    Autophagy, 2017-09-01;0(0):0.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  399. CLEC5A is a critical receptor in innate immunity against Listeria infection
    Authors: ST Chen, FJ Li, TY Hsu, SM Liang, YC Yeh, WY Liao, TY Chou, NJ Chen, M Hsiao, WB Yang, SL Hsieh
    Nat Commun, 2017-08-21;8(1):299.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  400. Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation
    Authors: SB Mkaddem, A Murua, H Flament, D Titeca-Bea, C Bounaix, L Danelli, P Launay, M Benhamou, U Blank, E Daugas, N Charles, RC Monteiro
    Nat Commun, 2017-08-15;8(1):246.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Specific calpain inhibition protects kidney against inflammaging
    Authors: G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie
    Sci Rep, 2017-08-14;7(1):8016.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  402. Interleukin-13 reduces cardiac injury and prevents heart dysfunction in viral myocarditis via enhanced M2 macrophage polarization
    Authors: H Yang, Y Chen, C Gao
    Oncotarget, 2017-08-10;8(59):99495-99503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  403. The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages
    Authors: KM Schneider, NB Watson, SB Minchenber, PT Massa
    Cytokine, 2017-08-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  404. Extracellular MicroRNAs Induce Potent Innate Immune Responses via TLR7/MyD88-Dependent Mechanisms
    Authors: Y Feng, L Zou, D Yan, H Chen, G Xu, W Jian, P Cui, W Chao
    J. Immunol., 2017-08-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  405. Commensal Gut Microbiota Immunomodulatory Actions in Bone Marrow and Liver have Catabolic Effects on Skeletal Homeostasis in Health
    Authors: CM Novince, CR Whittow, JD Aartun, JD Hathaway, N Poulides, MB Chavez, HM Steinkamp, KA Kirkwood, E Huang, C Westwater, KL Kirkwood
    Sci Rep, 2017-07-18;7(1):5747.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  406. CCL11, a novel mediator of inflammatory bone resorption
    Authors: E Kindstedt, CK Holm, R Sulniute, I Martinez-C, R Lundmark, P Lundberg
    Sci Rep, 2017-07-13;7(1):5334.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  407. The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis
    Authors: X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang
    Sci Rep, 2017-07-11;7(1):5107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  408. Hypomorphic A20 expression confers susceptibility to psoriasis
    Authors: A Aki, M Nagasaki, BA Malynn, A Ma, T Kagari
    PLoS ONE, 2017-06-28;12(6):e0180481.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  409. Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats
    Authors: H Huang, J Liu, H Hao, D Chen, L Zhizhong, M Li, H Song, R Xiang, C Jiang, X Fu, W Han
    Stem Cells Int, 2017-06-14;2017(0):2896874.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  410. Activity-independent targeting of mTOR to lysosomes in primary osteoclasts
    Authors: A Wang, LR Carraro-La, C Owen, B Gao, PN Corey, P Tyrrell, JH Brumell, I Voronov
    Sci Rep, 2017-06-07;7(1):3005.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice
    Authors: G Colaianni, T Mongelli, C Cuscito, P Pignataro, L Lippo, G Spiro, A Notarnicol, I Severi, G Passeri, G Mori, G Brunetti, B Moretti, U Tarantino, SC Colucci, JE Reseland, R Vettor, S Cinti, M Grano
    Sci Rep, 2017-06-06;7(1):2811.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  412. Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma
    Authors: JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun
    Mol. Cancer Ther., 2017-06-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Up-Regulation of RANK Expression via ERK1/2 by Insulin Contributes to the Enhancement of Osteoclast Differentiation
    Authors: JH Oh, NK Lee
    Mol. Cells, 2017-05-22;40(5):371-377.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  414. Barley Seedling Extracts Inhibit RANKL-Induced Differentiation, Fusion, and Maturation of Osteoclasts in the Early-to-Late Stages of Osteoclastogenesis
    Authors: SW Choi, SH Kim, KS Lee, HJ Kang, MJ Lee, KI Park, JH Lee, KD Park, WD Seo
    Evid Based Complement Alternat Med, 2017-05-08;2017(0):6072573.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  415. Muramyl Dipeptide, a Shared Structural Motif of Peptidoglycans, Is a Novel Inducer of Bone Formation through Induction of Runx2
    Authors: OJ Park, J Kim, J Yang, CH Yun, SH Han
    J. Bone Miner. Res, 2017-04-27;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6
    Authors: E Kim, J Beon, S Lee, SJ Park, H Ahn, MG Kim, JE Park, W Kim, JM Yuk, SJ Kang, SH Lee, EK Jo, RH Seong, S Kim
    Sci Adv, 2017-04-21;3(4):e1602296.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  417. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
    Authors: DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh
    Nat Commun, 2017-04-04;8(0):14919.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
    Authors: OC Olson, H Kim, DF Quail, EA Foley, JA Joyce
    Cell Rep, 2017-04-04;19(1):101-113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  419. VISTA deficiency accelerates the development of fatal murine lupus nephritis
    Authors: Sabrina Ceeraz
    Arthritis & rheumatology (Hoboken, N.J.), 2017-04-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  420. PPAR-? Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism
    Authors: YS Kim, HM Lee, JK Kim, CS Yang, TS Kim, M Jung, HS Jin, S Kim, J Jang, GT Oh, JM Kim, EK Jo
    J. Immunol, 2017-03-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  421. The Cytokine Response to Lipopolysaccharide Does Not Predict the Host Response to Infection
    Authors: BA Fensterhei, Y Guo, ER Sherwood, JK Bohannon
    J. Immunol, 2017-03-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  422. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors
    Authors: A Itoh-Nakad, M Matsumoto, H Kato, J Sasaki, Y Uehara, Y Sato, R Ebina-Shib, M Morooka, R Funayama, K Nakayama, K Ochiai, A Muto, K Igarashi
    Cell Rep, 2017-03-07;18(10):2401-2414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice
    Authors: Erivan S Ramos-Juni
    J. Bone Miner. Res, 2017-03-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Metabolic origins of spatial organization in the tumor microenvironment
    Authors: C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier
    Proc. Natl. Acad. Sci. U.S.A, 2017-02-28;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  425. 25-hydroxycholesterol promotes RANKL-induced osteoclastogenesis through coordinating NFATc1 and Sp1 complex in the transcription of miR-139-5p
    Authors: L Zhang, Y Lv, G Xian, Y Lin
    Biochem. Biophys. Res. Commun, 2017-02-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  426. TRPV1 deletion impaired fracture healing and inhibited osteoclast and osteoblast differentiation
    Authors: LH He, M Liu, Y He, E Xiao, L Zhao, T Zhang, HQ Yang, Y Zhang
    Sci Rep, 2017-02-22;7(0):42385.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  427. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
    Authors: S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen
    Sci Rep, 2017-02-17;7(0):42846.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  428. Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase inhibitors
    Authors: F Strålberg, A Kassem, F Kasprzykow, M Abrahamson, A Grubb, C Lindholm, UH Lerner
    J. Leukoc. Biol, 2017-02-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury
    Authors: HH Chen, H Yuan, H Cho, Y Feng, S Ngoy, AT Kumar, R Liao, W Chao, L Josephson, DE Sosnovik
    Theranostics, 2017-02-08;7(4):814-825.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  430. Dynamics of the sealing zone in cultured osteoclasts
    Authors: Sarit Batsir
    Cytoskeleton (Hoboken), 2017-02-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  431. Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro
    Authors: F Zhou, Y Shen, B Liu, X Chen, L Wan, D Peng
    Biochem. Biophys. Res. Commun, 2017-02-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  432. Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKC�
    Authors: HJ Koh, YR Kim, JS Kim, JS Yun, K Jang, CS Yang
    PLoS Pathog, 2017-01-26;13(1):e1006126.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  433. OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo
    Authors: HJ Ihn, T Lee, JA Kim, D Lee, ND Kim, HI Shin, YC Bae, EK Park
    PLoS ONE, 2017-01-13;12(1):e0170159.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  434. NF-?B activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection
    Authors: J Liu, J Xiang, X Li, S Blankson, S Zhao, J Cai, Y Jiang, HP Redmond, JH Wang
    Sci Rep, 2017-01-12;7(0):40418.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  435. Scaling of titanium implants entrains inflammation-induced osteolysis
    Authors: M Eger, N Sterer, T Liron, D Kohavi, Y Gabet
    Sci Rep, 2017-01-06;7(0):39612.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  436. Mycobacterium avium MAV2054 protein induces macrophage apoptosis by targeting mitochondria and reduces intracellular bacterial growth
    Sci Rep, 2016-11-30;6(0):37804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  437. Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation
    Authors: Janko Kos
    Neuropharmacology, 2016-11-23;114(0):88-100.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  438. Treatment with cestode parasite antigens recruits CCR2+ myeloid cells, the adoptive transfer of which ameliorates colitis
    Infect Immun, 2016-11-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
    Sci Rep, 2016-11-15;6(0):37211.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  440. Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway
    Authors: Dechun Geng
    Acta Biomater, 2016-11-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  441. Docosahexaenoic acid signaling attenuates the proliferation and differentiation of bone marrow-derived osteoclast precursors and promotes apoptosis in mature osteoclasts
    Authors: Young-Ran Yoon
    Cell. Signal., 2016-11-09;29(0):226-232.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart
    Eur J Immunol, 2016-10-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  443. Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages
    Oncotarget, 2016-10-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  444. Mycobacterium abscessus ESX-3 plays an important role in host inflammatory and pathological responses during infection
    Microbes Infect, 2016-09-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  445. Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis
    Eur J Immunol, 2016-09-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  446. Defect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4(+) T-cell proliferation
    Int J Nanomedicine, 2016-09-02;11(0):4357-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  447. TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance
    EMBO Mol Med, 2016-09-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  448. The Role of Prostate Apoptosis Response-4 (Par-4) in Mycobacterium tuberculosis Infected Macrophages
    Sci Rep, 2016-08-24;6(0):32079.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  449. Negative regulation of NF-?B p65 activity by serine 536 phosphorylation.
    Authors: Jean-Philippe Pradère, Céline Hernandez, Christiane Koppe, Richard A Friedman, Tom Luedde, Robert F Schwabe
    Science Signaling, 2016-08-23;0(0):1937-9145.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  450. MicroRNAs: Potential Biomarkers and Therapeutic Targets for Alveolar Bone Loss in Periodontal Disease
    Int J Mol Sci, 2016-08-11;17(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  451. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    Cell, 2016-08-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  452. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
    Circ Res, 2016-07-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  453. TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus
    Authors: L Bossaller, A Christ, K Pelka, K Nündel, PI Chiang, C Pang, N Mishra, P Busto, RG Bonegio, RE Schmidt, E Latz, A Marshak-Ro
    J. Immunol., 2016-06-27;197(4):1044-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  454. The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes.
    Authors: Hernandez A, Bohannon J, Luan L, Fensterheim B, Guo Y, Patil N, McAdams C, Wang J, Sherwood E
    J Leukoc Biol, 2016-06-27;100(6):1311-1322.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  455. Negative regulation of bacterial killing and inflammation by two novel CD16 ligands
    Eur J Immunol, 2016-06-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  456. Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease
    Authors: J Fu, S Li, R Feng, H Ma, F Sabeh, GD Roodman, J Wang, S Robinson, XE Guo, T Lund, D Normolle, MY Mapara, SJ Weiss, S Lentzsch
    J Clin Invest, 2016-04-04;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  457. Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.
    Authors: Khor E, Fanshawe B, Qi Y, Zolotukhin S, Kulkarni R, Enriquez R, Purtell L, Lee N, Wee N, Croucher P, Campbell L, Herzog H, Baldock P
    PLoS ONE, 2016-01-29;11(1):e0148155.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  458. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta.
    Authors: McCarthy R, Lu D, Alkhateeb A, Gardeck A, Lee C, Wessling-Resnick M
    J Neuroinflammation, 2016-01-27;13(1):21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  459. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
    Authors: Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, Popovych N, Helgason E, Schoeffler A, Jeet S, Ramamoorthi N, Kategaya L, Newman R, Horikawa K, Dugger D, Sandoval W, Mukund S, Zindal A, Martin F, Quan C, Tom J, Fairbrother W, Townsend M, Warming S, DeVoss J, Liu J, Dueber E, Caplazi P, Lee W, Goodnow C, Balazs M, Yu K, Kolumam G, Dixit V
    Nature, 2015-12-09;528(7582):370-5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  460. Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fc? Receptor (Fc?R) Function
    Authors: L Ren, A Campbell, H Fang, S Gautam, S Elavazhaga, K Fatehchand, P Mehta, A Stiff, BF Reader, X Mo, JC Byrd, WE Carson, JP Butchar, S Tridandapa
    J. Biol. Chem, 2015-12-01;291(6):3043-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  461. Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer's Disease.
    Authors: Guo J, Pan J, Xiong L, Xia W, Cui S, Xiong W
    PLoS ONE, 2015-11-17;10(11):e0139395.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  462. Mouse Resistin (mRetn): cloning, expression and purification in Escherichia coli and the potential regulative effects on murine bone marrow hematopoiesis.
    Authors: Wang F, Gao J, Malisani A, Xi X, Han W, Wan X
    BMC Biotechnol, 2015-11-16;15(0):105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  463. Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway.
    Authors: Ihn H, Lee D, Lee T, Kim S, Shin H, Bae Y, Hong J, Park E
    PLoS ONE, 2015-11-04;10(11):e0142201.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  464. Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-kappaB Ligand and Tumor Necrosis Factor Alpha Secretion.
    Authors: Pesce Viglietti A, Arriola Benitez P, Gentilini M, Velasquez L, Fossati C, Giambartolomei G, Delpino M
    Infect Immun, 2015-10-12;84(1):11-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  465. Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease.
    Authors: Oberoi R, Bogalle E, Matthes L, Schuett H, Koch A, Grote K, Schieffer B, Schuett J, Luchtefeld M
    PLoS ONE, 2015-09-14;10(9):e0137924.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  466. Bone Cell-autonomous Contribution of Type 2 Cannabinoid Receptor to Breast Cancer-induced Osteolysis.
    Authors: Sophocleous A, Marino S, Logan J, Mollat P, Ralston S, Idris A
    J Biol Chem, 2015-07-20;290(36):22049-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  467. CHMP5 controls bone turnover rates by dampening NF-kappaB activity in osteoclasts.
    Authors: Greenblatt M, Park K, Oh H, Kim J, Shin D, Lee J, Lee J, Singh A, Lee K, Hu D, Xiao C, Charles J, Penninger J, Lotinun S, Baron R, Ghosh S, Shim J
    J Exp Med, 2015-07-20;212(8):1283-301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  468. FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans.
    Authors: Yu H, Herbert B, Valerio M, Yarborough L, Hsu L, Argraves K
    Lipids Health Dis, 2015-07-04;14(0):66.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  469. The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERalpha Signaling in Osteoblasts and Osteoclasts.
    Authors: Ucer S, Iyer S, Bartell S, Martin-Millan M, Han L, Kim H, Weinstein R, Jilka R, O'Brien C, Almeida M, Manolagas S
    J Bone Miner Res, 2015-07-01;30(7):1138-49.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  470. Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappaB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts.
    Authors: Kassem A, Henning P, Lundberg P, Souza P, Lindholm C, Lerner U
    J Biol Chem, 2015-06-17;290(33):20147-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  471. Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism.
    Authors: Tan Z, Xie N, Cui H, Moellering D, Abraham E, Thannickal V, Liu G
    J Immunol, 2015-05-11;194(12):6082-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  472. Sexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations.
    Authors: Herbert B, Valerio M, Gaestel M, Kirkwood K
    PLoS ONE, 2015-05-06;10(5):e0125387.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  473. Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation.
    Authors: Mediero A, Ramkhelawon B, Perez-Aso M, Moore K, Cronstein B
    J Bone Miner Res, 2015-05-01;30(5):837-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  474. MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during Mycobacterial Infection.
    Authors: Kim J, Yuk J, Kim S, Kim T, Jin H, Yang C, Jo E
    J Immunol, 2015-04-27;194(11):5355-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  475. Regulation of L-type Voltage Gated Calcium Channel CACNA1S in Macrophages upon Mycobacterium tuberculosis Infection.
    Authors: Antony C, Mehto S, Tiwari B, Singh Y, Natarajan K
    PLoS ONE, 2015-04-27;10(4):e0124263.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  476. ERK5 Activation Is Essential for Osteoclast Differentiation.
    Authors: Amano, Shigeru, Chang, Yu-Tzu, Fukui, Yasuhisa
    PLoS ONE, 2015-04-17;10(4):e0125054.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  477. WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling.
    Authors: Maeda A, Ono M, Holmbeck K, Li L, Kilts T, Kram V, Noonan M, Yoshioka Y, McNerny E, Tantillo M, Kohn D, Lyons K, Robey P, Young M
    J Biol Chem, 2015-04-11;290(22):14004-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  478. 15-deoxy-delta12,14-prostaglandin j2 inhibits osteolytic breast cancer bone metastasis and estrogen deficiency-induced bone loss.
    Authors: Kim K, Kim H, Lee S, Ma G, Park K, Chung W
    PLoS ONE, 2015-04-10;10(4):e0122764.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  479. Immune complexes regulate bone metabolism through FcRgamma signalling.
    Authors: Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H
    Nat Commun, 2015-03-31;6(0):6637.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  480. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
    Authors: Jha A, Huang S, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, Chmielewski K, Stewart K, Ashall J, Everts B, Pearce E, Driggers E, Artyomov M
    Immunity, 2015-03-17;42(3):419-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  481. Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo.
    Authors: Martin I, Caban-Hernandez K, Figueroa-Santiago O, Espino A
    J Immunol, 2015-03-16;194(8):3924-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  482. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.
    Authors: Li, Chang-Ju, Cheng, Peng, Liang, Meng-Ke, Chen, Yu-Si, Lu, Qiong, Wang, Jin-Yu, Xia, Zhu-Ying, Zhou, Hou-De, Cao, Xu, Xie, Hui, Liao, Er-Yuan, Luo, Xiang-Ha
    J Clin Invest, 2015-03-09;125(4):1509-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  483. IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages.
    Authors: Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y
    J Immunol, 2015-02-27;194(7):3156-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  484. The ketone metabolite beta-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Authors: Youm Y, Nguyen K, Grant R, Goldberg E, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti T, Kang S, Horvath T, Fahmy T, Crawford P, Biragyn A, Alnemri E, Dixit V
    Nat Med, 2015-02-16;21(3):263-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  485. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.
    Authors: Yang C, Kim J, Kim T, Lee P, Kim S, Lee H, Shin D, Nguyen L, Lee M, Jin H, Kim K, Lee C, Kim M, Park S, Kim J, Choi H, Jo E
    Nat Commun, 2015-02-06;6(0):6115.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  486. Anabolic bone formation via a site-specific bone-targeting delivery system by interfering with semaphorin 4D expression.
    Authors: Zhang Y, Wei L, Miron R, Shi B, Bian Z
    J Bone Miner Res, 2015-02-01;30(2):286-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  487. A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts.
    Authors: Matsushita M, Ozaki Y, Hasegawa Y, Terada F, Tabata N, Shiheido H, Yanagawa H, Oikawa T, Matsuo K, Du W, Yamada T, Hozumi M, Ichikawa D, Hattori Y
    PLoS ONE, 2015-01-24;10(1):e0116135.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  488. Sim1 inhibits bone formation by enhancing the sympathetic tone in male mice.
    Authors: Wang X, Wei W, Zinn A, Wan Y
    Endocrinology, 2015-01-21;156(4):1408-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  489. Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures.
    Authors: Fowler T, Kamalakar A, Akel N, Kurten R, Suva L, Gaddy D
    J Cell Sci, 2015-01-20;128(4):683-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  490. The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases.
    Authors: Ozanne J, Prescott A, Clark K
    Biochem J, 2015-01-15;465(2):271-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  491. GPCR-mediated PLCbetagamma/PKCbeta/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis.
    Authors: Xu X, Gera N, Li H, Yun M, Zhang L, Wang Y, Wang Q, Jin T
    Mol Biol Cell, 2015-01-07;26(5):874-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  492. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
    Authors: Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M
    Autophagy, 2015-01-01;11(2):271-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  493. Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate.
    Authors: Purdue, P Edward, Crotti, Tania N, Shen, Zhenxin, Swantek, Jennifer, Li, Jun, Hill, Jonathan, Hanidu, Adedayo, Dimock, Janice, Nabozny, Gerald, Goldring, Steven R, McHugh, Kevin P
    Sci Rep, 2014-12-23;4(0):7595.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  494. Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis.
    Authors: Alshbool F, Mohan S
    PLoS ONE, 2014-12-05;9(12):e114357.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  495. Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice.
    Authors: Behler F, Maus R, Bohling J, Knippenberg S, Kirchhof G, Nagata M, Jonigk D, Izykowski N, Magel L, Welte T, Yamasaki S, Maus U
    Infect Immun, 2014-10-20;83(1):184-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  496. Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice.
    Authors: Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, Cherkas A, Tang X, Qin X
    Mol Ther, 2014-10-20;23(2):339-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  497. GM-CSF treated F4/80+ BMCs improve murine hind limb ischemia similar to M-CSF differentiated macrophages.
    Authors: Kuwahara G, Nishinakamura H, Kojima D, Tashiro T, Kodama S
    PLoS ONE, 2014-09-09;9(9):e106987.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  498. Toll-like receptor 9 mediated responses in cardiac fibroblasts.
    Authors: Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger O, Dahl T, Aukrust P, Finsen A, Yndestad A, Vinge L
    PLoS ONE, 2014-08-15;9(8):e104398.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  499. Lipocalin 2 is a regulator of macrophage polarization and NF-kappaB/STAT3 pathway activation.
    Authors: Guo H, Jin D, Chen X
    Mol Endocrinol, 2014-08-15;28(10):1616-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  500. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase.
    Authors: Tang, Songqing, Chen, Taoyong, Yu, Zhou, Zhu, Xuhui, Yang, Mingjin, Xie, Bin, Li, Nan, Cao, Xuetao, Wang, Jianli
    Nat Commun, 2014-08-14;5(0):4657.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  501. Modulation of osteoclastogenesis with macrophage M1- and M2-inducing stimuli.
    Authors: Jeganathan S, Fiorino C, Naik U, Sun H, Harrison R
    PLoS ONE, 2014-08-07;9(8):e104498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  502. IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
    Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
    J Immunol, 2014-08-04;193(6):3036-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  503. An unexpected twist to the activation of IKKbeta: TAK1 primes IKKbeta for activation by autophosphorylation.
    Authors: Zhang J, Clark K, Lawrence T, Peggie M, Cohen P
    Biochem J, 2014-08-01;461(3):531-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  504. Identification of novel transcription factors in osteoclast differentiation using genome-wide analysis of open chromatin determined by DNase-seq.
    Authors: Inoue K, Imai Y
    J Bone Miner Res, 2014-08-01;29(8):1823-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  505. Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions.
    Authors: Zhao T, Ding X, Du H, Yan C
    J Immunol, 2014-07-07;193(4):1942-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  506. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.
    Authors: Krzeszinski J, Wei W, Huynh H, Jin Z, Wang X, Chang T, Xie X, He L, Mangala L, Lopez-Berestein G, Sood A, Mendell J, Wan Y
    Nature, 2014-06-25;512(7515):431-5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  507. Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8.
    Authors: Abe T, Shin J, Hosur K, Udey M, Chavakis T, Hajishengallis G
    J Immunol, 2014-06-23;193(3):1383-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  508. DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo.
    Authors: Isaac, J, Erthal, J, Gordon, J, Duverger, O, Sun, H-W, Lichtler, A C, Stein, G S, Lian, J B, Morasso, M I
    Cell Death Differ, 2014-06-20;21(9):1365-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  509. SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.
    Authors: Mercken E, Mitchell S, Martin-Montalvo A, Minor R, Almeida M, Gomes A, Scheibye-Knudsen M, Palacios H, Licata J, Zhang Y, Becker K, Khraiwesh H, Gonzalez-Reyes J, Villalba J, Baur J, Elliott P, Westphal C, Vlasuk G, Ellis J, Sinclair D, Bernier M, de Cabo R
    Aging Cell, 2014-06-16;13(5):787-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  510. Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.
    Authors: Wu L, Ong S, Talor M, Barin J, Baldeviano G, Kass D, Bedja D, Zhang H, Sheikh A, Margolick J, Iwakura Y, Rose N, Cihakova D
    J Exp Med, 2014-06-16;211(7):1449-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  511. Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1.
    Authors: Zhao C, Pavicic P, Datta S, Sun D, Novotny M, Hamilton T
    J Immunol, 2014-06-11;193(2):879-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  512. NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-kappaB.
    Authors: Zhang H, Hilton M, Anolik J, Welle S, Zhao C, Yao Z, Li X, Wang Z, Boyce B, Xing L
    J Clin Invest, 2014-06-02;124(7):3200-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  513. Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
    Authors: Ohba T, Cole H, Cates J, Slosky D, Haro H, Ando T, Schwartz H, Schoenecker J
    J Bone Miner Res, 2014-06-01;29(6):1431-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  514. A nonapoptotic role for CASP2/caspase 2: modulation of autophagy.
    Authors: Tiwari, Meenaksh, Sharma, Lokendra, Vanegas, Difernan, Callaway, Danielle, Bai, Yidong, Lechleiter, James D, Herman, Brian
    Autophagy, 2014-06-01;10(6):1054-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  515. Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
    Authors: Teramachi J, Zhou H, Subler M, Kitagawa Y, Galson D, Dempster D, Windle J, Kurihara N, Roodman G
    J Bone Miner Res, 2014-06-01;29(6):1456-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  516. A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.
    Authors: Gilmour J, Assi S, Jaegle U, Kulu D, van de Werken H, Clarke D, Westhead D, Philipsen S, Bonifer C
    Development, 2014-05-21;141(12):2391-401.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  517. miR-27a regulates inflammatory response of macrophages by targeting IL-10.
    Authors: Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal V, Liu G
    J Immunol, 2014-05-16;193(1):327-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  518. Reactive oxygen species induce the association of SHP-1 with c-Src and the oxidation of both to enhance osteoclast survival.
    Authors: Ke K, Sul O, Choi E, Safdar A, Kim E, Choi H
    Am J Physiol Endocrinol Metab, 2014-05-13;307(1):E61-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  519. Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment.
    Authors: Chaturvedi, Pallavi, Gilkes, Daniele, Takano, Naoharu, Semenza, Gregg L
    Proc Natl Acad Sci U S A, 2014-05-05;111(20):E2120-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  520. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation.
    Authors: Bartell, Shoshana, Kim, Ha-Neui, Ambrogini, Elena, Han, Li, Iyer, Srividhy, Serra Ucer, S, Rabinovitch, Peter, Jilka, Robert L, Weinstein, Robert S, Zhao, Haibo, O'Brien, Charles, Manolagas, Stavros, Almeida, Maria
    Nat Commun, 2014-04-30;5(0):3773.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  521. A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 induction.
    Authors: Chang Y, Chen T, Wu Y, Chen G, Weng T, Tseng P, Hsieh S, Fu S, Lin C, Chen C, Chu C, Chio I, Mak T, Chen N
    J Cell Mol Med, 2014-04-24;18(7):1344-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  522. The pro-inflammatory cytokine, interleukin-6, enhances the polarization of alternatively activated macrophages.
    Authors: Fernando M, Reyes J, Iannuzzi J, Leung G, McKay D
    PLoS ONE, 2014-04-15;9(4):e94188.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  523. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
    Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
    Nature, 2014-04-13;509(7499):235-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  524. Kruppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.
    Authors: Karpurapu M, Ranjan R, Deng J, Chung S, Lee Y, Xiao L, Nirujogi T, Jacobson J, Park G, Christman J
    PLoS ONE, 2014-04-02;9(4):e93362.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  525. Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts.
    Authors: Sharma, Ramaswam, Callaway, Danielle, Vanegas, Difernan, Bendele, Michelle, Lopez-Cruzan, Marisa, Horn, Diane, Guda, Teja, Fajardo, Roberto, Abboud-Werner, Sherry, Herman, Brian
    PLoS ONE, 2014-04-01;9(4):e93696.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  526. Distinct actions of akt1 on skeletal architecture and function.
    Authors: Mukherjee, Aditi, Larson, Emily A, Klein, Robert F, Rotwein, Peter
    PLoS ONE, 2014-03-24;9(3):e93040.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  527. C5L2 is required for C5a-triggered receptor internalization and ERK signaling.
    Authors: Hsu W, Yang F, Lin C, Hsieh S, Chen N
    Cell Signal, 2014-03-12;26(7):1409-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  528. Osteocytes produce interferon-beta as a negative regulator of osteoclastogenesis.
    Authors: Hayashida C, Ito J, Nakayachi M, Okayasu M, Ohyama Y, Hakeda Y, Sato T
    J Biol Chem, 2014-03-07;289(16):11545-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  529. Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI.
    Authors: Al Faraj, Achraf, Sultana Shaik, Asma, Pureza, Mary Ang, Alnafea, Mohammad, Halwani, Rabih
    PLoS ONE, 2014-03-05;9(3):e90829.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  530. Changes of microRNA profile and microRNA-mRNA regulatory network in bones of ovariectomized mice.
    Authors: An J, Ohn J, Song J, Yang J, Park H, Choi H, Kim S, Kim S, Park W, Shin C
    J Bone Miner Res, 2014-03-01;29(3):644-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  531. Anti-osteoclastogenic activity of praeruptorin A via inhibition of p38/Akt-c-Fos-NFATc1 signaling and PLCgamma-independent Ca2+ oscillation.
    Authors: Yeon J, Kim K, Choi S, Moon S, Park Y, Ryu B, Oh J, Kim M, Erkhembaatar M, Son Y, Kim S
    PLoS ONE, 2014-02-21;9(2):e88974.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  532. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014-02-20;4(0):4146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  533. EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1alpha with Th17/Treg control.
    Authors: Yang E, Lee J, Lee S, Kim E, Moon Y, Jung Y, Park S, Cho M
    PLoS ONE, 2014-02-18;9(2):e86062.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  534. Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes.
    Authors: Jego G, Lanneau D, de Thonel A, Berthenet K, Hazoume A, Droin N, Hamman A, Girodon F, Bellaye P, Wettstein G, Jacquel A, Duplomb L, Le Mouel A, Papanayotou C, Christians E, Bonniaud P, Lallemand-Mezger V, Solary E, Garrido C
    Leukemia, 2014-02-07;28(8):1676-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  535. A macrophage-specific synthetic promoter for therapeutic application of adiponectin.
    Authors: Kang, W S, Kwon, J S, Kim, H B, Jeong, H-Y, Kang, H J, Jeong, M H, Cho, J G, Park, J C, Kim, Y S, Ahn, Y
    Gene Ther, 2014-02-06;21(4):353-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  536. OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis.
    Authors: Gwyer Findlay, Emily, Danks, Lynett, Madden, Jodie, Cavanagh, Mary M, McNamee, Kay, McCann, Fiona, Snelgrove, Robert J, Shaw, Stevan, Feldmann, Marc, Taylor, Peter Ch, Horwood, Nicole J, Hussell, Tracy
    Proc Natl Acad Sci U S A, 2014-01-27;111(6):2289-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  537. The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
    Authors: McMichael B, Scherer K, Franklin N, Lee B
    PLoS ONE, 2014-01-23;9(1):e87402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  538. Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity.
    Authors: David M, Machuca-Gayet I, Kikuta J, Ottewell P, Mima F, LeBlanc R, Bonnelye E, Ribeiro J, Holen I, Lopez Vales R, Jurdic P, Chun J, Clezardin P, Ishii M, Peyruchaud O
    J Biol Chem, 2014-01-15;289(10):6551-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  539. The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis.
    Authors: Yao C, Yao G, Sun B, Zhang C, Tommasini S, Insogna K
    J Biol Chem, 2014-01-06;289(10):6775-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  540. Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization.
    Authors: Date D, Das R, Narla G, Simon D, Jain M, Mahabeleshwar G
    J Biol Chem, 2014-01-02;289(15):10318-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  541. MafB promotes atherosclerosis by inhibiting foam-cell apoptosis.
    Authors: Hamada, Michito, Nakamura, Megumi, Tran, Mai Thi, Moriguchi, Takashi, Hong, Cynthia, Ohsumi, Takayuki, Dinh, Tra Thi, Kusakabe, Manabu, Hattori, Motochik, Katsumata, Tokio, Arai, Satoko, Nakashima, Katsuhik, Kudo, Takashi, Kuroda, Etsushi, Wu, Chien-Hu, Kao, Pei-Han, Sakai, Masaharu, Shimano, Hitoshi, Miyazaki, Toru, Tontonoz, Peter, Takahashi, Satoru
    Nat Commun, 2014-01-01;5(0):3147.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  542. TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.
    Authors: Sun Q, Sammut B, Wang F, Kurihara N, Windle J, Roodman G, Galson D
    J Bone Miner Res, 2014-01-01;29(1):90-102.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  543. Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast.
    Authors: Hirose J, Masuda H, Tokuyama N, Omata Y, Matsumoto T, Yasui T, Kadono Y, Hennighausen L, Tanaka S
    J Exp Med, 2013-12-23;211(1):153-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  544. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
    Authors: Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh-hora M, Kodama T, Tanaka S, Bluestone J, Takayanagi H
    Nat Med, 2013-12-22;20(1):62-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  545. Aged mice are unable to mount an effective myeloid response to sepsis.
    Authors: Nacionales D, Gentile L, Vanzant E, Lopez M, Cuenca A, Cuenca A, Ungaro R, Li Y, Baslanti T, Bihorac A, Moore F, Baker H, Leeuwenburgh C, Moldawer L, Efron P
    J Immunol, 2013-12-13;192(2):612-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  546. The newly discovered cytokine IL-34 is expressed in gingival fibroblasts, shows enhanced expression by pro-inflammatory cytokines, and stimulates osteoclast differentiation.
    Authors: Bostrom E, Lundberg P
    PLoS ONE, 2013-12-10;8(12):e81665.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  547. Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation.
    Authors: Xiu Y, Xu H, Zhao C, Li J, Morita Y, Yao Z, Xing L, Boyce B
    J Clin Invest, 2013-12-09;124(1):297-310.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  548. Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-kappaB pathway and attenuating ROS production.
    Authors: Lee S, Lee K, Yi S, Kook S, Lee J
    PLoS ONE, 2013-12-04;8(12):e80873.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  549. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013-11-27;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  550. Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease.
    Authors: Stalvey M, Clines K, Havasi V, McKibbin C, Dunn L, Chung W, Clines G
    PLoS ONE, 2013-11-13;8(11):e80098.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  551. T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance.
    Authors: Zhong, Jixin, Rao, Xiaoquan, Braunstein, Zachary, Taylor, Anne, Narula, Vimal, Hazey, Jeffrey, Mikami, Dean, Needleman, Bradley, Rutsky, Jessica, Sun, Qinghua, Deiuliis, Jeffrey, Satoskar, Abhay R, Rajagopalan, Sanjay
    Diabetes, 2013-11-12;63(4):1289-302.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  552. Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma.
    Authors: Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, Ruan J, Xia L
    Cancer Res, 2013-10-24;73(24):7254-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  553. Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.
    Authors: Biosse Duplan, Martin, Zalli, Detina, Stephens, Sebastie, Zenger, Serhan, Neff, Lynn, Oelkers, J Margit, Lai, Frank P, Horne, William, Rottner, Klemens, Baron, Roland
    Mol Cell Biol, 2013-10-21;34(1):16-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  554. Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis.
    Authors: Muruganandan S, Dranse H, Rourke J, McMullen N, Sinal C
    Stem Cells, 2013-10-01;31(10):2172-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  555. Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.
    Authors: Xia W, Jung J, Shun C, Xiong S, Xiong L, Shi X, Mei L, Xiong W
    J Bone Miner Res, 2013-10-01;28(10):2122-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  556. Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-kappaB activity and c-Fos induction and prevents inflammatory bone loss in mice.
    Authors: Kim H, Yoon K, Yoon H, Hong J, Lee M, Lee I, Kim S
    J Leukoc Biol, 2013-05-08;94(1):99-107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  557. Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors.
    Authors: Hunter, K E, Palermo, C, Kester, J C, Simpson, K, Li, J-P, Tang, L H, Klimstra, D S, Vlodavsky, I, Joyce, J A
    Oncogene, 2013-05-06;33(14):1799-808.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  558. Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.
    Authors: Jacome-Galarza C, Lee S, Lorenzo J, Aguila H
    J Bone Miner Res, 2013-05-01;28(5):1203-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  559. Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover.
    Authors: Braun T, Lepper J, Ruiz Heiland G, Hofstetter W, Siegrist M, Lezuo P, Gaestel M, Rumpler M, Thaler R, Klaushofer K, Distler J, Schett G, Zwerina J
    J Bone Miner Res, 2013-04-01;28(4):936-47.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  560. RNA interference-mediated silencing of Atp6i prevents both periapical bone erosion and inflammation in the mouse model of endodontic disease.
    Authors: Ma, Junqing, Chen, Wei, Zhang, Lijie, Tucker, Byron, Zhu, Guochun, Sasaki, Hajime, Hao, Liang, Wang, Lin, Ci, Honglian, Jiang, Hongbing, Stashenko, Philip, Li, Yi-Ping
    Infect Immun, 2013-04-01;81(4):1021-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  561. Differential immune responses to Segniliparus rotundus and Segniliparus rugosus infection and analysis of their comparative virulence profiles.
    Authors: Kim J, Kim W, Lee K, Won C, Kim J, Eum S, Koh W, Shin S
    PLoS ONE, 2013-03-29;8(3):e59646.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  562. Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity.
    Authors: Yang Z, Grinchuk V, Urban J, Bohl J, Sun R, Notari L, Yan S, Ramalingam T, Keegan A, Wynn T, Shea-Donohue T, Zhao A
    2013-03-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  563. Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers.
    Authors: Elcombe S, Naqvi S, van den Bosch M, Mackenzie K, Cianfanelli F, Brown G, Arthur J
    PLoS ONE, 2013-03-22;8(3):e60086.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  564. Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling.
    Authors: Xia W, Tang F, Xiong L, Xiong S, Jung J, Lee D, Li X, Feng X, Mei L, Xiong W
    J Cell Biol, 2013-03-18;200(6):821-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  565. Fas-mediated inflammatory response in Listeria monocytogenes infection.
    Authors: Uchiyama R, Yonehara S, Tsutsui H
    J Immunol, 2013-03-15;190(8):4245-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  566. Toll-like receptor 2 ligands regulate monocyte Fcgamma receptor expression and function.
    Authors: Shah P, Fatehchand K, Patel H, Fang H, Justiniano S, Mo X, Jarjoura D, Tridandapani S, Butchar J
    J Biol Chem, 2013-03-15;288(17):12345-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  567. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
    Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
    Eur J Immunol, 2013-03-06;43(4):979-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  568. Caffeine enhances osteoclast differentiation and maturation through p38 MAP kinase/Mitf and DC-STAMP/CtsK and TRAP pathway.
    Authors: Choi J, Choi S, Lee S, Lee J, Kim H, Lee S, Lee N
    Cell Signal, 2013-02-19;25(5):1222-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  569. Overexpression of developmentally regulated GTP-binding protein-2 increases bone loss.
    Authors: Ke K, Sul O, Kim W, Lee M, Ko M, Suh J, Kim H, Kim S, Park J, Choi H
    Am J Physiol Endocrinol Metab, 2013-01-29;304(7):E703-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  570. Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13.
    Authors: Pau E, Loh C, Minty G, Chang N, Wither J
    Genes Immun, 2013-01-17;14(3):154-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  571. Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34).
    Cytokine, 2012-12-19;61(2):630-8.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  572. Talin1 and Rap1 are critical for osteoclast function.
    Authors: Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley S, Critchley D, Petrich B, Morozov A, Ginsberg M, Teitelbaum S
    Mol Cell Biol, 2012-12-10;33(4):830-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  573. TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.
    Authors: Lamothe B, Lai Y, Xie M, Schneider M, Darnay B
    Mol Cell Biol, 2012-11-19;33(3):582-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  574. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  575. Role of c-Jun N-terminal protein kinase 1/2 (JNK1/2) in macrophage-mediated MMP-9 production in response to Moraxella catarrhalis lipooligosaccharide (LOS).
    Authors: Hassan F, Ren D, Zhang W
    PLoS ONE, 2012-05-24;7(5):e37912.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  576. Osteoprotection by semaphorin 3A.
    Authors: Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H
    Nature, 2012-05-03;485(7396):69-74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  577. Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer.
    Authors: Zhao E, Wang L, Dai J, Kryczek I, Wei S, Vatan L, Altuwaijri S, Sparwasser T, Wang G, Keller E, Zou W
    Oncoimmunology, 2012-03-01;1(2):152-161.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  578. Macrophages participate in IL-17-mediated inflammation.
    Authors: Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Quader F, Chen P, Zheng D, Caturegli P, Rose NR, Cihakova D
    Eur. J. Immunol., 2012-01-23;42(3):726-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  579. Inactivation of glycogen synthase kinase-3beta is required for osteoclast differentiation.
    Authors: Jang HD, Shin JH, Park DR, Hong JH, Yoon K, Ko R, Ko CY, Kim HS, Jeong D, Kim N, Lee SY
    J. Biol. Chem., 2011-09-23;286(45):39043-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  580. Macrophage infiltration predicts a poor prognosis for human ewing sarcoma.
    Authors: Fujiwara T, Fukushi J, Yamamoto S, Matsumoto Y, Setsu N, Oda Y, Yamada H, Okada S, Watari K, Ono M, Kuwano M, Kamura S, Iida K, Okada Y, Koga M, Iwamoto Y
    Am. J. Pathol., 2011-07-21;179(3):1157-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  581. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
    Authors: Cook BD, Liu S, Evans T
    Blood, 2011-04-22;117(24):6489-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  582. Inhibition of osteoclastogenesis by mechanically loaded osteocytes: involvement of MEPE.
    Authors: Kulkarni RN, Bakker AD, Everts V, Klein-Nulend J
    Calcif. Tissue Int., 2010-08-20;87(5):461-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  583. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010-08-09;185(6):3677-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  584. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
    Authors: Scapini P, Hu Y, Chu CL
    J. Exp. Med., 2010-07-12;207(8):1757-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  585. Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation.
    Authors: Shanmugarajan S, Beeson CC, Reddy SV
    Endocrinology, 2010-07-07;151(9):4389-99.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  586. Transient overexpression of sonic hedgehog alters the architecture and mechanical properties of trabecular bone.
    Authors: Kiuru M, Solomon J, Ghali B, van der Meulen M, Crystal RG, Hidaka C
    J. Bone Miner. Res., 2009-09-01;24(9):1598-607.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  587. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro.
    Authors: Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS
    Bone, 2009-04-18;45(2):309-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  588. Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.
    Authors: Binder NB, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig TM, Mack M, Erben RG, Smolen JS, Redlich K
    Nat. Med., 2009-03-29;15(4):417-24.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  589. Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling.
    Authors: Walker EC, McGregor NE, Poulton IJ, Pompolo S, Allan EH, Quinn JM, Gillespie MT, Martin TJ, Sims NA
    J. Bone Miner. Res., 2008-12-01;23(12):2025-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  590. Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment.
    Authors: Jinushi M, Nakazaki Y, Carrasco DR, Draganov D, Souders N, Johnson M, Mihm MC, Dranoff G
    Cancer Res., 2008-11-01;68(21):8889-98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  591. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.
    Authors: Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M
    EMBO J., 2008-01-24;27(3):535-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  592. Imatinib promotes osteoblast differentiation by inhibiting PDGFR signaling and inhibits osteoclastogenesis by both direct and stromal cell-dependent mechanisms.
    Authors: O'Sullivan S, Naot D, Callon K, Porteous F, Horne A, Wattie D, Watson M, Cornish J, Browett P, Grey A
    J. Bone Miner. Res., 2007-11-01;22(11):1679-89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  593. Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
    Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N
    J. Immunol., 2007-07-01;179(1):639-46.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  594. Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells.
    Authors: Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T
    Biochem. Biophys. Res. Commun., 2007-06-12;360(2):346-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  595. The Fas/Fas ligand system inhibits differentiation of murine osteoblasts but has a limited role in osteoblast and osteoclast apoptosis.
    Authors: Kovacic N, Lukic IK, Grcevic D, Katavic V, Croucher P, Marusic A
    J. Immunol., 2007-03-15;178(6):3379-89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  596. Hematopoietic stem cell-targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice.
    Authors: Johansson MK, de Vries TJ, Schoenmaker T, Ehinger M, Brun AC, Fasth A, Karlsson S, Everts V, Richter J
    Blood, 2007-03-01;109(12):5178-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  597. Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells.
    Authors: Nakanishi M, Niidome T, Matsuda S, Akaike A, Kihara T, Sugimoto H
    Eur. J. Neurosci., 2007-02-01;25(3):649-58.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  598. Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel.
    Authors: Mohamedali KA, Poblenz AT, Sikes CR, Navone NM, Thorpe PE, Darnay BG, Rosenblum MG
    Cancer Res., 2006-11-15;66(22):10919-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  599. Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density.
    Authors: Jia D, O'Brien CA, Stewart SA, Manolagas SC, Weinstein RS
    Endocrinology, 2006-08-24;147(12):5592-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  600. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
    Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
    J. Biol. Chem., 2006-08-04;281(39):28794-801.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  601. Gingival fibroblasts are better at inhibiting osteoclast formation than periodontal ligament fibroblasts.
    Authors: de Vries TJ, Schoenmaker T, Wattanaroonwong N, van den Hoonaard M, Nieuwenhuijse A, Beertsen W, Everts V
    J. Cell. Biochem., 2006-05-15;98(2):370-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  602. Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
    Authors: Conway</LastName><ForeNam JG</Initia, Conway JG, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT
    Proc. Natl. Acad. Sci. U.S.A., 2005-10-25;102(44):16078-83.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  603. Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine).
    Authors: Gevrey JC, Isaac BM, Cox D
    J. Immunol., 2005-09-15;175(6):3737-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  604. Development of a culture system that supports adult microglial cell proliferation and maintenance in the resting state.
    Authors: Ponomarev ED, Novikova M, Maresz K, Shriver LP, Dittel BN
    J. Immunol. Methods, 2005-04-26;300(1):32-46.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  605. IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.
    Authors: Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB
    J. Immunol., 2004-05-15;172(10):6476-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  606. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells.
    Authors: Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL
    J. Biol. Chem., 2002-11-06;278(3):1561-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. How long will recombinant mouse M-CSF last in cell culture?

    • End-users will need to determine the appropriate concentration and timing when adding Recombinant Mouse M-CSF Proteins to cell culturing experiments. The addition of protein may be dependent on certain culture conditions, including the cell number, density, and media content. For techniques and methodologies, we recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.

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Reviews for Recombinant Mouse M-CSF Protein

Average Rating: 4.7 (Based on 18 Reviews)

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Recombinant Mouse M-CSF Protein
By Anonymous on 02/24/2022
Application: CellProlif
Reason for Rating: It works good in a 10ng/ml concentration.

We used macrophage in a media contain 10ng/ml recombinant mouse Recombinant Mouse M-CSF Protein.

Recombinant Mouse M-CSF Protein
By Anonymous on 06/09/2021
Application: Cell migration/motility
Recombinant Mouse M-CSF Protein
By Anonymous on 05/21/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse M-CSF Protein
By Anonymous on 03/24/2021
Application: CellProlif
Reason for Rating: We used this to induce the bone derived macrophage in mice. It worked good even in a low concentration.

We suspended macrophage in a media contain (10% FBS+1% antibiotic, 10ng/ml recombinant mouse Recombinant Mouse M-CSF Protein)

Cell Proliferation Recombinant Mouse M-CSF Protein 416-ML
Recombinant Mouse M-CSF Protein
By Anonymous on 04/17/2020
Application: CellProlif
Recombinant Mouse M-CSF Protein
By Yan Wang on 11/15/2019
Application: Stem/Immune cell maintenance or differentiation
Recombinant Mouse M-CSF Protein
By Joanna Plastira on 06/10/2019
Application: In vitro bioactivity in cell culture

Microglia were isolated from adult mice and kept in culture. Medium was supplemented with 10ng/ml M-CSF and it refreshed after 3 days.

In vitro bioactivity in cell culture Recombinant Mouse M-CSF Protein 416-ML
Recombinant Mouse M-CSF Protein
By Joseph Moore on 01/09/2019
Application: In vitro bioactivity in cell culture
Reason for Rating: We used this in bone marrow macrophages to induce osteoblast. It works great cells can easily been seen under a scope. We later ran TRAP staining

Plate cells 5X10^6 on 10cm dishes. After 3 hours change media to 60 ng/ml MSCF.

Recombinant Mouse M-CSF Protein
By Yan Wang on 11/20/2018
Application: Cell migration/motility
Reason for Rating: The cells migrated well attracted by the M-CSF
Cell migration/motility Recombinant Mouse M-CSF Protein 416-ML
Recombinant Mouse M-CSF Protein
By Anonymous on 11/02/2017

Reason for Rating: We use this to induce the bone derived macrophage from mouse. It worked well in a relatively low concentration.
Recombinant Mouse M-CSF Protein 416-ML
Recombinant Mouse M-CSF Protein
By Xiaoming Zhou on 10/20/2017
Application: Stimulate the monocyte in bone marrow of mice into macrophage.
Reason for Rating: Due to the tight budget plan, we used the M-CFS as a relatively low concentration as 10ng/ml. But it works well.

bone marrow was flushed from femurs, and tibias and resuspended in bone marrow C-BMDM(10% FBS+1% penicillin/streptomycin , 10ng/ml recombinant mouse M-CSF).

Other Recombinant Mouse M-CSF Protein 416-ML
Recombinant Mouse M-CSF Protein
By Sitara Sankar on 07/20/2017
Application: Media additive for protein or antibody production
Recombinant Mouse M-CSF Protein
By Anonymous on 02/01/2017
Application: In vivo study
Recombinant Mouse M-CSF Protein
By Anonymous on 07/21/2016
Application: Osteoclast differentiation assay
Recombinant Mouse M-CSF Protein
By jingbin wang on 05/24/2016
Application: SDS-PAGE Control
Recombinant Mouse M-CSF Protein
By Anonymous on 05/16/2016
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Worked as expected
Recombinant Mouse M-CSF Protein
By Beata Lecka-Czernik on 05/16/2016
Application: Media additive for protein or antibody production
Recombinant Mouse M-CSF Protein
By Beata Lecka-Czernik on 01/18/2016
Application: Stem/Immune cell maintenance or differentiation