Home / TNF-alpha / Recombinant Mouse TNF-alpha (aa 80-235) Protein

Recombinant Mouse TNF-alpha (aa 80-235) Protein

Catalog #: 410-MT
313 Citations 14 Reviews Datasheet / COA / SDS

Carrier Free

Catalog # Availability Size / Price Qty
410-MT-010/CF
410-MT-050/CF
410-MT-025/CF
410-MT-100/CF
410-MT-01M/CF

With Carrier

Catalog # Availability Size / Price Qty
410-MT-010
410-MT-050
410-MT-025
410-MT-100
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Graph showing dose-dependent bioactivity of mouse TNF-alpha protein
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Product Details
Citations (313)
FAQs
Reviews (14)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse TNF-alpha (aa 80-235) Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED50 for this effect is 8-50 pg/mL.
Source
E. coli-derived mouse TNF-alpha protein
Leu80-Leu235, with an N-terminal Met
Accession #
P06804
N-terminal Sequence
Analysis
Met & Ser84
Structure / Form
A small amount of recombinant protein lacking the N-terminal methionine and four additional amino acid residues may be also present.
Predicted Molecular Mass
17 kDa

Product Datasheets

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410-MT (with carrier)

Product Datasheet
COA
SDS

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410-MT/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

410-MT

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

410-MT/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

Bioactivity Graph showing dose-dependent bioactivity of mouse TNF-alpha protein View Larger

Recombinant mouse TNF-alpha (410-MT) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 8-50 pg/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TNF-alpha

Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (1, 2). Mouse TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 179 aa extracellular domain (ECD) (3). Within the ECD, mouse TNF-alpha shares 94% aa sequence identity with rat and 70%-77% with bovine, canine, cotton rat, equine, feline, human, porcine, rat, and rhesus TNF-alpha. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells (1, 2). TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (4). Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I (2, 5). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (6-8). TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (9, 10) and the hematopoietic cell-restricted 80 kDa TNF RII (11, 12), both of which are also expressed as homotrimers (1, 2, 13). Both type I and type II receptors bind TNF-alpha with comparable affinity (14), although only TNF RI contains a cytoplasmic death domain which triggers the activation of apoptosis. Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha (15).

References
  1. Zelova, H. and J. Hosek (2013) Inflamm. Res. 62:641.
  2. Juhasz, K. et al. (2013) Expert Rev. Clin. Immunol. 9:335.
  3. Fransen, L. et al. (1985) Nucleic Acids Res. 13:4417.
  4. Tang, P. et al. (1996) Biochemistry 35:8216.
  5. Perez, C. et al. (1990) Cell 63:251.
  6. Black, R.A. et al. (1997) Nature 385:729.
  7. Moss, M.L. et al. (1997) Nature 385:733.
  8. Gearing, A.J.H. et al. (1994) Nature 370:555.
  9. Schall, T.J. et al. (1990) Cell 61:361.
  10. Loetscher, H. et al. (1990) Cell 61:351.
  11. Dembic, Z. et al. (1990) Cytokine 2:231.
  12. Smith, C.A. et al. (1990) Science 248:1019.
  13. Loetscher, H. et al. (1991) J. Biol. Chem. 266:18324.
  14. Pinckard, J.K. et al. (1997) J. Biol. Chem. 272:10784.
  15. Engelmann, H. et al. (1990) J. Biol. Chem. 265:1531.
Long Name
Tumor Necrosis Factor alpha
Entrez Gene IDs
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 102139631 (Cynomolgus Monkey); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Citations for Recombinant Mouse TNF-alpha (aa 80-235) Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

313 Citations: Showing 1 - 10
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  1. Eupatolide, isolated from Liriodendron tulipifera, sensitizes TNF-mediated dual modes of apoptosis and necroptosis by disrupting RIPK1 ubiquitination
    Authors: Park, KA;Jung, CS;Sohn, KC;Ju, E;Shin, S;Park, I;Na, M;Hur, GM;
    Heliyon
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection
    Authors: Yang, F;Beltran-Lobo, P;Sung, K;Goldrick, C;Croft, CL;Nishimura, A;Hedges, E;Mahiddine, F;Troakes, C;Golde, TE;Perez-Nievas, BG;Hanger, DP;Noble, W;Jimenez-Sanchez, M;
    Science advances
    Species: Murine polyomavirus strain A3
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Embryo-derive TNF promotes decidualization via fibroblast activation
    Authors: Chen, ST;Shi, WW;Lin, YQ;Yang, ZS;Wang, Y;Li, MY;Li, Y;Liu, AX;Hu, Y;Yang, ZM;
    eLife
    Species: Mouse
    Sample Types: In Vivo
    Applications: In vivo assay
  4. Mechanoregulation of Osteoclastogenesis-Inducing Potentials of Fibrosarcoma Cell Line by Substrate Stiffness
    Authors: Tiskratok, W;Yamada, M;Watanabe, J;Pengyu, Q;Kimura, T;Egusa, H;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche
    Authors: Haensel, D;Daniel, B;Gaddam, S;Pan, C;Fabo, T;Bjelajac, J;Jussila, AR;Gonzalez, F;Li, NY;Chen, Y;Hou, J;Patel, T;Aasi, S;Satpathy, AT;Oro, AE;
    Nature communications
    Species: Mouse
    Sample Types: Organoids
    Applications: Cell Culture
  6. Mycophenolic acid directly protects podocytes by preserving the actin cytoskeleton and increasing cell survival
    Authors: SED Abo Zed, A Hackl, K Bohl, L Ebert, E Kieckhöfer, C Müller, K Becker, G Fink, KD Nüsken, E Nüsken, RU Müller, B Schermer, LT Weber
    Scientific Reports, 2023-03-15;13(1):4281.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. BAFF induces CXCR5 expression during B cell differentiation in bone marrow
    Authors: H Koizumi, W Fujii, C Sanjoba, Y Goto
    Biochemistry and Biophysics Reports, 2023-03-07;34(0):101451.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Disruption to tRNA modification by queuine contributes to inflammatory bowel disease
    Authors: J Zhang, Y Zhang, CJ McGrenagha, VP Kelly, Y Xia, J Sun
    Cellular and Molecular Gastroenterology and Hepatology, 2023-02-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge
    Authors: CM Schafer, S Martin-Alm, K Kurylowicz, N Dufton, L Osuna-Alma, ML Wu, CF Johnson, AV Shah, DO Haskard, A Buxton, E Willis, K Wheeler, S Turner, M Chlebicz, RP Scott, S Kovats, A Cleuren, GM Birdsey, AM Randi, CT Griffin
    bioRxiv : the preprint server for biology, 2023-02-11;0(0):.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay
  10. RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1alpha
    Authors: PA Dumesic, SE Wilensky, S Bose, JG Van Vranke, SP Gygi, BM Spiegelman
    bioRxiv : the preprint server for biology, 2023-01-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Identification of astrocyte regulators by nucleic acid cytometry
    Authors: IC Clark, MA Wheeler, HG Lee, Z Li, LM Sanmarco, S Thaploo, CM Polonio, SW Shin, G Scalisi, AR Henry, JM Rone, F Giovannoni, M Charabati, CF Akl, DM Aleman, SEJ Zandee, A Prat, DC Douek, EA Boritz, FJ Quintana, AR Abate
    Nature, 2023-01-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Interleukin-38 suppresses abdominal aortic aneurysm formation in mice by regulating macrophages in an IL1RL2-p38 pathway-dependent manner
    Authors: S Kurose, Y Matsubara, S Yoshino, K Yoshiya, K Morisaki, T Furuyama, T Hoshino, T Yoshizumi
    Physiological Reports, 2023-01-01;11(2):e15581.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Improved beta-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes
    Authors: H Memetimin, B Zhu, S Lee, WS Katz, PA Kern, BS Finlin
    Scientific Reports, 2022-12-24;12(1):22291.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  14. Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance
    Authors: S Zia, BP Hammond, M Zirngibl, A Sizov, CS Baaklini, SP Panda, MFS Ho, KV Lee, A Mainali, MK Burr, S Williams, AV Caprariell, C Power, T Simmen, BJ Kerr, JR Plemel
    Molecular Neurodegeneration, 2022-12-13;17(1):82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. RAGE activation in macrophages and development of experimental diabetic polyneuropathy
    Authors: S Osonoi, H Mizukami, Y Takeuchi, H Sugawa, S Ogasawara, S Takaku, T Sasaki, K Kudoh, K Ito, K Sango, R Nagai, Y Yamamoto, M Daimon, H Yamamoto, S Yagihashi
    JCI Insight, 2022-12-08;7(23):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Double knockin mice show NF-kappaB trajectories in immune signaling and aging
    Authors: SMT Rahman, M Aqdas, EW Martin, F Tomassoni, P Songkiatis, KS Oh, S Uderhardt, S Yun, QC Claybourne, RA McDevitt, V Greco, RN Germain, L Tessarollo, MH Sung
    Cell Reports, 2022-11-22;41(8):111682.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Zinc Transporter 8 Haploinsufficiency Protects Against Beta Cell Dysfunction in Type 1 Diabetes by Increasing Mitochondrial Respiration
    Authors: YK Kim, JA Walters, ND Moss, KL Wells, R Sheridan, JG Miranda, RKP Benninger, LL Pyle, RM O'Brien, L Sussel, HW Davidson
    Molecular Metabolism, 2022-11-05;66(0):101632.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  18. Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis
    Authors: J Tong, XT Lan, Z Zhang, Y Liu, DY Sun, XJ Wang, SX Ou-Yang, CL Zhuang, FM Shen, P Wang, DJ Li
    Acta pharmacologica Sinica, 2022-11-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Desmoglein-2 is important for islet function and beta-cell survival
    Authors: KK Myo Min, D Rojas-Cana, D Penko, M DeNichilo, MP Cockshell, CB Ffrench, EJ Thompson, O Asplund, CJ Drogemulle, RB Prasad, L Groop, ST Grey, HE Thomas, T Loudovaris, TW Kay, MG Mahoney, CF Jessup, PT Coates, CS Bonder
    Cell Death & Disease, 2022-10-29;13(10):911.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
    Authors: A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandr, S Bhattachar, S Affo, N Fujiwara, H Su, Q Sun, TM Savage, JR Wilson-Kan, JM Caviglia, L Chin, D Chen, X Wang, S Caruso, JK Kang, AD Amin, S Wallace, R Dobie, D Yin, OM Rodriguez-, C Yin, A Mehal, B Izar, RA Friedman, RG Wells, UB Pajvani, Y Hoshida, HE Remotti, N Arpaia, J Zucman-Ros, M Karin, NC Henderson, I Tabas, RF Schwabe
    Nature, 2022-10-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms
    Authors: T Huu Hoang, M Sato-Matsu, H Yuasa, T Matsubara, LTT Thuy, H Ikenaga, DM Phuong, NV Hanh, VN Hieu, DV Hoang, H Hai, Y Okina, M Enomoto, A Tamori, A Daikoku, H Urushima, K Ikeda, NQ Dat, Y Yasui, H Shinkawa, S Kubo, R Yamagishi, N Ohtani, K Yoshizato, J Gracia-San, N Kawada
    Science Advances, 2022-09-28;8(39):eabo5525.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria
    Authors: SM Bader, SP Preston, K Saliba, A Lipszyc, ZL Grant, L Mackiewicz, A Baldi, A Hempel, MP Clark, T Peiris, W Clow, J Bjelic, MD Stutz, P Arandjelov, J Teale, F Du, L Coultas, JM Murphy, CC Allison, M Pellegrini, AL Samson
    Oncogene, 2022-07-23;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  23. Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement
    Authors: H Kamei, T Ishii, Y Nishii
    Oncogene, 2022-06-02;12(1):9243.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Humanized beta2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation
    Authors: T Bromberger, S Klapproth, M Sperandio, M Moser
    Cells, 2022-05-03;11(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy
    Authors: FA Graca, M Rai, LC Hunt, A Stephan, YD Wang, B Gordon, R Wang, G Quarato, B Xu, Y Fan, M Labelle, F Demontis
    Nature Communications, 2022-05-02;13(1):2370.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  26. IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis
    Authors: H Fujita, T Fujita, H Fujii
    Cells, 2022-04-25;11(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
    Authors: W Piao, L Li, V Saxena, J Iyyathurai, R Lakhan, Y Zhang, IT Lape, C Paluskievi, KL Hippen, Y Lee, E Silverman, MW Shirkey, LV Riella, BR Blazar, JS Bromberg
    Nature Communications, 2022-04-21;13(1):2176.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
    Authors: B Czaya, K Heitman, I Campos, C Yanucil, D Kentrup, D Westbrook, O Gutierrez, JL Babitt, G Jung, IB Salusky, M Hanudel, C Faul
    Elife, 2022-03-18;11(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  29. Ferroptosis as a Novel Determinant of beta-Cell Death in Diabetic Conditions
    Authors: A Stancic, T Saksida, M Markelic, M Vucetic, I Grigorov, V Martinovic, D Gajic, A Ivanovic, K Velickovic, N Savic, V Otasevic
    Oxidative Medicine and Cellular Longevity, 2022-03-14;2022(0):3873420.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  30. Paeoniflorin Ameliorates Skeletal Muscle Atrophy in Chronic Kidney Disease via AMPK/SIRT1/PGC-1alpha-Mediated Oxidative Stress and Mitochondrial Dysfunction
    Authors: Q Li, J Wu, J Huang, R Hu, H You, L Liu, D Wang, L Wei
    Frontiers in Pharmacology, 2022-03-08;13(0):859723.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  31. ADAM8 signaling drives neutrophil migration and ARDS severity
    Authors: C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch
    JCI Insight, 2022-02-08;7(3):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  32. Spinal microglia-derived TNF promotes the astrocytic JNK/CXCL1 pathway activation in a mouse model of burn pain
    Authors: R Zhang, B Xu, N Zhang, J Niu, M Zhang, Q Zhang, D Chen, Y Shi, D Chen, K Liu, X Zhang, N Li, Q Fang
    Brain, Behavior, and Immunity, 2022-02-07;102(0):23-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Interferon-gamma Preferentially Promotes Necroptosis of Lung Epithelial Cells by Upregulating MLKL
    Authors: Q Hao, S Shetty, TA Tucker, S Idell, H Tang
    Cells, 2022-02-06;11(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. TREM-1 is required for enhanced OpZ-induced superoxide generation following priming
    Authors: S Murthy, S Baruah, JL Bowen, K Keck, BA Wagner, GR Buettner, DB Sykes, J Klesney-Ta
    Journal of leukocyte biology, 2022-01-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Comparative Phosphoproteomics of Neuro-2a Cells under Insulin Resistance Reveals New Molecular Signatures of Alzheimer's Disease
    Authors: D Kim, YS Jo, HS Jo, S Bae, YW Kwon, YS Oh, JH Yoon
    International Journal of Molecular Sciences, 2022-01-17;23(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Behavioural immune landscapes of inflammation
    Authors: G Crainiciuc, M Palomino-S, M Molina-Mor, J Sicilia, DG Aragones, JLY Li, R Madurga, JM Adrover, A Aroca-Crev, S Martin-Sal, AS Del Valle, SD Castillo, HCE Welch, O Soehnlein, M Graupera, F Sánchez-Ca, A Zarbock, TE Smithgall, M Di Pilato, TR Mempel, PL Tharaux, SF González, A Ayuso-Saci, LG Ng, GF Calvo, I González-D, F Díaz-de-Ma, A Hidalgo
    Nature, 2022-01-05;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  37. Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease
    Authors: Y Cheng, TR Hall, X Xu, I Yung, D Souza, J Zheng, F Schiele, M Hoffmann, ML Mbow, JP Garnett, J Li
    EBioMedicine, 2021-12-18;75(0):103758.
    Species: Mouse, Transgenic Mouse
    Sample Types: Organoid
    Applications: Bioassay
  38. ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-kappaB
    Authors: M Won, KA Park, S Kim, E Ju, Y Ko, H Yoo, H Ro, J Lee, J Oh, EG Lee, SY Kim, SW Nam, HM Shen, MK Yeo, JM Kim, GM Hur
    Cell Death and Differentiation, 2021-11-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
    Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
    Cell Reports, 2021-11-23;37(8):110037.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  40. Dose and Dose Rate-Dependent Effects of Low-Dose Irradiation on Inflammatory Parameters in ApoE-Deficient and Wild Type Mice
    Authors: A Glasow, I Patties, ND Priest, REJ Mitchel, G Hildebrand, K Manda
    Cells, 2021-11-20;10(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma
    Authors: N Miyashita, T Enokido, M Horie, K Fukuda, H Urushiyama, C Strell, H Brunnström, P Micke, A Saito, T Nagase
    Scientific Reports, 2021-11-17;11(1):22380.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Gasdermin D deficiency attenuates arthritis induced by traumatic injury but not autoantibody-assembled immune complexes
    Authors: T Yang, K Sun, C Wang, G Swarnkar, S Quan, D Kress, J Xiao, Y Alippe, H Zheng, RH Brophy, D Hao, A McAlinden, Y Abu-Amer, J Shen, G Mbalaviele
    Arthritis Research & Therapy, 2021-11-16;23(1):286.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Differential Cytokine-Induced Responses of Polarized Microglia
    Authors: P Chauhan, WS Sheng, S Hu, S Prasad, JR Lokensgard
    Brain sciences, 2021-11-10;11(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons
    Authors: Y Shi, S Li, H Zhang, J Zhu, T Che, B Yan, J Li, C Liu
    Journal of Neuroinflammation, 2021-11-08;18(1):261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
    Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
    The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair
    Authors: Y Zhang, Y Zheng, F Shu, R Zhou, B Bao, S Xiao, K Li, Q Lin, L Zhu, Z Xia
    Carbohydrate polymers, 2021-10-16;276(0):118752.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan
    Authors: E Håland, IN Moen, E Veidal, H Hella, K Misund, TS Slørdahl, KK Starheim
    Oncotarget, 2021-10-12;12(21):2158-2168.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  48. Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKbeta promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
    Authors: I Papazian, E Tsoukala, A Boutou, M Karamita, K Kambas, L Iliopoulou, R Fischer, RE Kontermann, MC Denis, G Kollias, H Lassmann, L Probert
    Journal of Neuroinflammation, 2021-09-26;18(1):222.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Tumor Necrosis Factor-alpha utilizes MAPK/NFkappaB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway
    Authors: SM Pokharel, K Chiok, NK Shil, I Mohanty, S Bose
    PLoS ONE, 2021-09-22;16(9):e0257576.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis
    Authors: T Zhou, E DeRoo, H Yang, A Stranz, Q Wang, R Ginnan, HA Singer, B Liu
    Cells, 2021-09-12;10(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways
    Authors: A Gluschko, A Farid, M Herb, D Grumme, M Krönke, M Schramm
    Autophagy, 2021-09-05;0(0):1-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. PI3K/ NF-kappaB-dependent TNF-alpha and HDAC activities facilitate LPS-induced RGS10 suppression in pulmonary macrophages
    Authors: F Almutairi, SL Tucker, D Sarr, B Rada
    Cellular Signalling, 2021-07-31;86(0):110099.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis
    Authors: X Guo, J Bai, G Ge, Z Wang, Q Wang, K Zheng, H Tao, L Zhang, H Zhang, D Wang, X Zhang, H Li, G Pan, D Geng
    Journal of colloid and interface science, 2021-07-24;605(0):410-424.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. alpha-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFalpha/IFNgamma Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube
    Authors: K Sumi, M Sakuda, K Munakata, K Nakamura, K Ashida
    Nutrients, 2021-07-13;13(7):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects
    Authors: J Sadek, DT Hall, B Colalillo, A Omer, AK Tremblay, V Sanguin-Ge, W Muller, S Di Marco, ME Bianchi, IE Gallouzi
    Embo Molecular Medicine, 2021-06-07;0(0):e13591.
    Species: Mouse
    Sample Types: Organoid
    Applications: Bioassay
  56. Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice
    Authors: MB Preda, CA Neculachi, IM Fenyo, AM Vacaru, MA Publik, M Simionescu, A Burlacu
    Cell Death & Disease, 2021-06-02;12(6):566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
    Authors: V Farré-Alin, A Palomino-A, P Narros-Fer, AB Lopez-Rodr, C Decouty-Pe, A Muñoz-Mont, J Zamorano-F, B Mansilla-F, J Giner-Garc, P García-Fei, M Sáez-Alegr, AJ Palpán-Flo, JM Roda-Frade, CS Carabias, JM Rosa, B Civantos-M, S Yus-Teruel, L Gandía, A Lagares, BJ Hernández-, J Egea
    Biomedicines, 2021-05-25;9(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1
    Authors: J Zhao, B Cai, Z Shao, L Zhang, Y Zheng, C Ma, F Yi, B Liu, C Gao
    Cell Death and Differentiation, 2021-05-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Effect of NIR Laser Therapy by MLS-MiS Source on Fibroblast Activation by Inflammatory Cytokines in Relation to Wound Healing
    Authors: S Genah, F Cialdai, V Ciccone, E Sereni, L Morbidelli, M Monici
    Biomedicines, 2021-03-16;9(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Tumor necrosis factor &alpha negatively regulates the retrieval and reconsolidation of hippocampus-dependent memory
    Authors: S Takahashi, H Fukushima, Z Yu, H Tomita, S Kida
    Brain, Behavior, and Immunity, 2021-03-05;94(0):79-88.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  61. Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation
    Authors: M Jafari, AM Schumacher, N Snaidero, EM Ullrich Ga, T Neziraj, V Kocsis-Jut, D Engels, T Jürgens, I Wagner, JDF Weidinger, SS Schmidt, E Beltrán, N Hagan, L Woodworth, D Ofengeim, J Gans, F Wolf, M Kreutzfeld, R Portugues, D Merkler, T Misgeld, M Kerschenst
    Nature Neuroscience, 2021-01-25;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  62. Gut-licensed IFN&gamma+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
    Authors: LM Sanmarco, MA Wheeler, C Gutiérrez-, CM Polonio, M Linnerbaue, FA Pinho-Ribe, Z Li, F Giovannoni, KV Batterman, G Scalisi, SEJ Zandee, ES Heck, M Alsuwailm, DL Rosene, B Becher, IM Chiu, A Prat, FJ Quintana
    Nature, 2021-01-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells
    Authors: SA Rajput, MR Mirza, MI Choudhary
    PLoS ONE, 2020-12-21;15(12):e0241349.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice
    Authors: L Todd, C Finkbeiner, CK Wong, MJ Hooper, TA Reh
    Cell Reports, 2020-12-15;33(11):108507.
    Species: Transgenic Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  65. Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
    Authors: C Zhong, P Li, S Argade, L Liu, A Chilla', W Liang, H Xin, B Eliceiri, B Choudhury, N Ferrara
    Nature Communications, 2020-12-10;11(1):6330.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  66. The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
    Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
    J Neuroinflammation, 2020-10-14;17(1):299.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
    Authors: L Boytard, T Hadi, M Silvestro, H Qu, A Kumpfbeck, R Sleiman, KH Fils, D Alebrahim, F Boccalatte, M Kugler, A Corsica, BE Gelb, G Jacobowitz, G Miller, C Bellini, J Oakes, JS Silvestre, L Zangi, B Ramkhelawo
    Nat Commun, 2020-08-27;11(1):4311.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  68. Collagen VIalpha2 chain deficiency causes trabecular bone loss by potentially promoting osteoclast differentiation through enhanced TNFalpha signaling
    Authors: HT Pham, V Kram, QA Dar, T Komori, Y Ji, P Mohassel, J Rooney, L Li, TM Kilts, C Bonnemann, S Lamande, MF Young
    Sci Rep, 2020-08-13;10(1):13749.
    Species: Mouse
    Sample Types: Recombinant Proteins
    Applications: Bioassay
  69. Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
    Authors: M Liu, M Yan, H Lv, B Wang, X Lv, H Zhang, S Xiang, J Du, T Liu, Y Tian, X Zhang, F Zhou, T Cheng, Y Zhu, H Jiang, Y Cao, D Ai
    Cell Rep, 2020-08-04;32(5):107990.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Serum-borne lipids amplify TLR-activated inflammatory responses
    Authors: N Sharma, AS Akhade, S Ismaeel, A Qadri
    J. Leukoc. Biol., 2020-07-27;0(0):.
    Species: Mouse
    Sample Types: Primary Cells
    Applications: Cell Culture
  71. Isoform- and Cell Type-Specific Roles of Glycogen Synthase Kinase 3 N-Terminal Serine Phosphorylation in Liver Ischemia Reperfusion Injury
    Authors: M Ni, H Zhou, J Zhang, D Jin, T Lu, RW Busuttil, JW Kupiec-Weg, X Wang, Y Zhai
    J. Immunol., 2020-07-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  72. Paracrine regulation and improvement of &beta-cell function by thioredoxin
    Authors: EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn
    Redox Biol, 2020-05-16;34(0):101570.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  73. Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice
    Authors: MB Uccellini, SV Bardina, MT Sánchez-Ap, KM White, YJ Hou, JK Lim, A García-Sas
    Cell Rep, 2020-04-07;31(1):107498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Dissecting the Regulatory Strategies of NF-&kappaB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics
    Authors: KA Ngo, K Kishimoto, J Davis-Tura, A Pimplaskar, Z Cheng, R Spreafico, EY Chen, A Tam, G Ghosh, S Mitchell, A Hoffmann
    Cell Rep, 2020-02-25;30(8):2758-2775.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages
    Authors: A Ariana, NA Alturki, S Hajjar, DJ Stumpo, C Tiedje, ES Alnemri, M Gaestel, PJ Blackshear, S Sad
    J. Biol. Chem., 2020-02-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. MAFG-driven astrocytes promote CNS inflammation
    Authors: MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, BR Watson, G Scalisi, S Alkwai, V Rothhammer, A Rotem, JA Heyman, S Thaploo, LM Sanmarco, J Ragoussis, DA Weitz, K Petrecca, JR Moffitt, B Becher, JP Antel, A Prat, FJ Quintana
    Nature, 2020-02-12;0(0):.
    Species: Mouse
    Sample Types: Cells
    Applications: Cell Culture
  77. Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
    Authors: FC Simões, TJ Cahill, A Kenyon, D Gavriouchk, JM Vieira, X Sun, D Pezzolla, C Ravaud, E Masmanian, M Weinberger, S Mayes, ME Lemieux, DN Barnette, M Gunadasa-R, RM Williams, DR Greaves, LA Trinh, SE Fraser, SL Dallas, RP Choudhury, T Sauka-Spen, PR Riley
    Nat Commun, 2020-01-30;11(1):600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria
    Authors: TK Darling, PN Mimche, C Bray, B Umaru, LM Brady, C Stone, CE Eboumbou M, TE Lane, LS Ayong, TJ Lamb
    PLoS Pathog., 2020-01-30;16(1):e1008261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
    Authors: HQ Tran, RE Ley, AT Gewirtz, B Chassaing
    Nat Commun, 2019-12-11;10(1):5650.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  80. Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
    Authors: J Pennig, P Scherrer, MC Gissler, N Anto-Miche, N Hoppe, L Füner, C Härdtner, P Stachon, D Wolf, I Hilgendorf, A Mullick, C Bode, A Zirlik, IJ Goldberg, F Willecke
    Sci Rep, 2019-11-29;9(1):17937.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  81. Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy
    Authors: L Shi, J Wang, N Ding, Y Zhang, Y Zhu, S Dong, X Wang, C Peng, C Zhou, L Zhou, X Li, H Shi, W Wu, X Long, C Wu, W Liao
    Nat Commun, 2019-11-28;10(1):5421.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  82. O-GlcNAc transferase suppresses necroptosis and liver fibrosis
    Authors: B Zhang, MD Li, R Yin, Y Liu, Y Yang, KA Mitchell-R, JH Nam, R Li, L Wang, Y Iwakiri, D Chung, ME Robert, BE Ehrlich, AM Bennett, J Yu, MH Nathanson, X Yang
    JCI Insight, 2019-11-01;4(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
    Authors: S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, R Srinivasan, X Li, K Devarajan, L Prélot, CE Ang, Y Shibuya, BA Benayoun, ALS Chang, M Wernig, J Wysocka, MT Longaker, MP Snyder, A Brunet
    Nature, 2019-10-23;574(7779):553-558.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  84. Proteomic Analysis of 3T3-L1 Adipocytes Treated with Insulin and TNF-alpha
    Authors: H Chan, KP Bhide, A Vaidyam, V Hedrick, TJP Sobreira, TG Sors, RW Grant, UK Aryal
    Proteomes, 2019-10-20;7(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Serum amyloid A-mediated inflammasome activation of microglial cells in cerebral ischemia
    Authors: J Yu, H Zhu, S Taheri, W Mondy, L Bonilha, GS Magwood, D Lackland, RJ Adams, MS Kindy
    J. Neurosci., 2019-10-14;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Standard
  86. RIPK1 mediates TNF-induced intestinal crypt apoptosis during chronic NF-kappaB activation
    Authors: J Wong, R Garcia-Car, M Zelic, SB Ho, BS Boland, SJ Yao, SA Desai, S Das, N Planell, PA Harris, J Font-Burga, K Taniguchi, J Bertin, A Salas, M Pasparakis, PJ Gough, M Kelliher, M Karin, M Guma
    Cell Mol Gastroenterol Hepatol, 2019-10-10;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  87. The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin treatment
    Authors: T Kumrungsee, T Kariya, K Hashimoto, T Koyano, N Yazawa, T Hashimoto, Y Sanada, M Matsuyama, Y Sotomaru, H Sakurai, FAJ van de Loo, N Yanaka
    Sci Rep, 2019-10-01;9(1):14101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Stimulation
  88. Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice
    Authors: T Ondee, J Gillen, P Visitchana, P Somparn, J Issara-Amp, C Dang Phi, W Chancharoe, D Gurusamy, A Nita-Lazar, A Leelahavan
    Cells, 2019-09-11;8(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Phlda3 regulates beta cell survival during stress
    Authors: M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt
    Sci Rep, 2019-09-06;9(1):12827.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells
    Authors: HY Chiang, PH Chu, TH Lee
    J. Biomed. Sci., 2019-08-30;26(1):61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
    Authors: S Darkwah, N Nago, MG Appiah, PK Myint, E Kawamoto, M Shimaoka, EJ Park
    Biomedicines, 2019-07-18;7(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. TGFbeta-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis
    Authors: J Li, A Ayoub, Y Xiu, X Yin, JO Sanders, A Mesfin, L Xing, Z Yao, BF Boyce
    Nat Commun, 2019-06-26;10(1):2795.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Effect of TNF-α-Induced Sclerostin on Osteocytes during Orthodontic Tooth Movement
    Authors: F Ohori, H Kitaura, A Marahleh, A Kishikawa, S Ogawa, J Qi, WR Shen, T Noguchi, Y Nara, I Mizoguchi
    J Immunol Res, 2019-06-24;2019(0):9716758.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Transcriptional suppression of CPI-17 gene expression in vascular smooth muscle cells by TNF, KLF4, and Sp1 is associated with LPS-induced vascular hypocontractility, hypotension, and mortality
    Authors: G Zhao, Y Zhong, W Su, S Liu, X Song, T Hou, X Mu, MC Gong, Z Guo
    Mol. Cell. Biol., 2019-05-14;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  95. Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models
    Authors: N Zhang, DP Heruth, W Wu, LQ Zhang, MN Nsumu, K Shortt, K Li, X Jiang, B Wang, C Friesen, DY Li, SQ Ye
    Cell Biosci, 2019-05-14;9(0):40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  96. TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment
    Authors: P Zizza, R Dinami, M Porru, C Cingolani, E Salvati, A Rizzo, C D'Angelo, E Petti, CA Amoreo, M Mottolese, I Sperduti, A Chambery, R Russo, P Ostano, G Chiorino, G Blandino, A Sacconi, J Cherfils-V, C Leonetti, E Gilson, A Biroccio
    Nucleic Acids Res., 2019-04-23;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  97. DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
    Authors: A Arredouani, A Diane, N Khattab, I Bensmail, I Aoude, M Chikri, R Mohammad, AB Abou-Samra, M Dehbi
    Sci Rep, 2019-03-18;9(1):4772.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis
    Authors: M Qiu, K Huang, Y Liu, Y Yang, H Tang, X Liu, C Wang, H Chen, Y Xiong, J Zhang, J Yang
    Mucosal Immunol, 2019-02-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
    Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
    J. Immunol., 2019-01-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
    Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
    Mol Brain, 2018-12-18;11(1):75.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  101. NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis
    Authors: AE Vendrov, A Sumida, C Canugovi, A Lozhkin, T Hayami, NR Madamanchi, MS Runge
    Redox Biol, 2018-11-29;21(0):101063.
    Species: Mouse
    Sample Types:
    Applications: Bioassay
  102. The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting
    Authors: DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi
    EMBO Mol Med, 2018-07-01;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  103. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E
    Authors: A Aguilar-Va, N Haji, D De Gregori, E Matta-Cama, MJ Eslamizade, J Popic, V Sharma, R Cao, C Rummel, A Tanti, S Wiebe, N Nuñez, S Comai, R Nadon, G Luheshi, N Mechawar, G Turecki, JC Lacaille, G Gobbi, N Sonenberg
    Nat Commun, 2018-06-25;9(1):2459.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death
    Authors: I Martins, SQ Raza, L Voisin, H Dakhli, A Allouch, F Law, D Sabino, D De Jong, M Thoreau, E Mintet, D Dugué, M Piacentini, ML Gougeon, F Jaulin, P Bertrand, C Brenner, DM Ojcius, G Kroemer, N Modjtahedi, E Deutsch, JL Perfettini
    Cell Death Dis, 2018-06-18;9(7):716.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1
    Authors: D Rijal, A Ariana, A Wight, K Kim, NA Alturki, Z Aamir, E Ametepe, RG Korneluk, C Tiedje, MB Menon, M Gaestel, S McComb, S Sad
    J. Biol. Chem., 2018-06-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Physiological culture conditions alter myotube morphology and responses to atrophy treatments: implications for in�vitro research on muscle wasting
    Authors: E Archer-Lah, C Lan, RT Jagoe
    Physiol Rep, 2018-06-01;6(12):e13726.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
    Authors: Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi
    Sci Rep, 2018-05-30;8(1):8414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Chemokines cooperate with TNF to provide protective anti-viral immunity and to enhance inflammation
    Authors: A Alejo, MB Ruiz-Argüe, SM Pontejo, MDM Fernández, M Saraiva, B Hernáez, A Alcamí
    Nat Commun, 2018-05-03;9(1):1790.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice
    Authors: M Yassin, H Kissow, B Vainer, PD Joseph, A Hay-Schmid, J Olsen, AE Pedersen
    Sci Rep, 2018-05-02;8(1):6905.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  110. Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
    Authors: R Drolia, S Tenguria, AC Durkes, JR Turner, AK Bhunia
    Cell Host Microbe, 2018-04-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. ATF3 mediates the inhibitory action of TNF-α on osteoblast differentiation through the JNK signaling pathway
    Authors: BC Jeong
    Biochem. Biophys. Res. Commun., 2018-04-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
    Authors: G Meyer Zu H, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, R Sobel, A Regev, VK Kuchroo
    Immunity, 2018-03-20;48(3):556-569.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis
    Authors: T Kobori, S Hamasaki, A Kitaura, Y Yamazaki, T Nishinaka, A Niwa, S Nakao, H Wake, S Mori, T Yoshino, M Nishibori, H Takahashi
    Front Immunol, 2018-03-06;9(0):334.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome
    Authors: JE Kanter, F Kramer, S Barnhart, JM Duggan, M Shimizu-Al, V Kothari, A Chait, SD Bouman, JA Hamerman, BF Hansen, GS Olsen, KE Bornfeldt
    Diabetes, 2018-02-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  115. GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
    Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
    Mol Metab, 2018-02-23;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
    Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
    Elife, 2018-02-22;7(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  117. A real-time monitoring platform of myogenesis regulators using double fluorescent labeling
    Authors: E Sapoznik, G Niu, Y Zhou, PM Prim, TL Criswell, S Soker
    PLoS ONE, 2018-02-14;13(2):e0192654.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. An insight into the role of magnesium in the immunomodulatory properties of mesenchymal stem cells
    Authors: F da Silva L, AB da Rocha R, A Hastreiter, A Nogueira-P, E Makiyama, C Colli, RA Fock
    J. Nutr. Biochem., 2018-02-13;55(0):200-208.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
    Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
    Neurobiol. Dis., 2018-02-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  120. Corticosterone Preexposure Increases NF-?B Translocation and Sensitizes IL-1? Responses in BV2 Microglia-Like Cells
    Authors: J Liu, S Mustafa, DT Barratt, MR Hutchinson
    Front Immunol, 2018-01-22;9(0):3.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
    Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
    Neurobiol. Dis., 2018-01-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  122. Pharmacological Effect ofCaulophyllum robustumon Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-?B, and Proinflammatory Cytokines In Vivo and In Vitro
    Authors: QH Wang, SW Lv, YY Guo, JX Duan, SY Dong, QS Wang, FM Yu, H Su, HX Kuang
    Evid Based Complement Alternat Med, 2017-12-31;2017(0):8134321.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis
    Authors: EM Grössinger, M Kang, L Bouchareyc, R Sarin, DR Haudenschi, LN Borodinsky, IE Adamopoulo
    J. Immunol., 2017-12-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Possible involvement of NETosis in inflammatory processes in the eye: Evidence from a small cohort of patients
    Authors: T Barliya, R Dardik, Y Nisgav, M Dachbash, D Gaton, G Kenet, R Ehrlich, D Weinberger, T Livnat
    Mol. Vis., 2017-12-13;23(0):922-932.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  125. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
    Authors: H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita
    EBioMedicine, 2017-12-07;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  126. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition
    Authors: P Nancy, J Siewiera, G Rizzuto, E Tagliani, I Osokine, P Manandhar, I Dolgalev, C Clementi, A Tsirigos, A Erlebacher
    J. Clin. Invest., 2017-11-27;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question
    Authors: M Winther, A Holdfeldt, M Sundqvist, Z Rajabkhani, M Gabl, J Bylund, C Dahlgren, H Forsman
    PLoS ONE, 2017-09-21;12(9):e0185132.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017-09-07;2(17):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. TNF? drives mitochondrial stress in POMC neurons in obesity
    Authors: CX Yi, M Walter, Y Gao, S Pitra, B Legutko, S Kälin, C Layritz, C García-Các, M Bielohuby, M Bidlingmai, SC Woods, A Ghanem, KK Conzelmann, JE Stern, M Jastroch, MH Tschöp
    Nat Commun, 2017-05-10;8(0):15143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
    Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
    Mol Metab, 2017-05-06;6(7):725-736.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  131. Fibroblast reticular cells engineer a blastema extracellular network during digit tip regeneration in mice
    Authors: L Marrero, J Simkin, M Sammarco, K Muneoka
    Regeneration (Oxf), 2017-05-03;4(2):69-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia
    Authors: M Karamita, C Barnum, W Möbius, MG Tansey, DE Szymkowski, H Lassmann, L Probert
    JCI Insight, 2017-04-20;2(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
    Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
    Nat. Immunol., 2017-04-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Endogenous TNF? orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation
    Authors: S Arokiasamy, C Zakian, J Dilliway, W Wang, S Nourshargh, MB Voisin
    Sci Rep, 2017-03-13;7(0):44189.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  135. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
    Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
    J. Nutr. Biochem, 2017-03-06;44(0):11-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
    Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
    J. Allergy Clin. Immunol, 2017-03-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
    Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
    Cell Death Discov, 2017-02-27;3(0):16097.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Extracellular Vesicles from Bone Marrow-Derived Mesenchymal Stem Cells Improve Survival from Lethal Hepatic Failure in Mice
    Authors: H Haga, IK Yan, K Takahashi, A Matsuda, T Patel
    Stem Cells Transl Med, 2017-02-18;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  139. Increased mitochondrial ROS generation mediates the loss of PVAT anticontractile effect in HFD-treated obese mice
    Authors: Rafael Menezes da Costa
    Br. J. Pharmacol, 2017-01-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  140. Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia
    Authors: T Tsunekawa, R Banno, A Mizoguchi, M Sugiyama, T Tominaga, T Onoue, D Hagiwara, Y Ito, S Iwama, M Goto, H Suga, Y Sugimura, H Arima
    EBioMedicine, 2017-01-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  141. Disruption of Lipid Raft Function Increases Expression and Secretion of Monocyte Chemoattractant Protein-1 in 3T3-L1 Adipocytes
    PLoS ONE, 2016-12-28;11(12):e0169005.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice
    J Immunol, 2016-08-26;0(0):.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, Neutralization
  143. RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
    Cell Death Differ, 2016-05-13;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  144. Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
    Authors: P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi
    Oncogene, 2016-04-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
    Authors: Shweta Pasi
    J Biol Chem, 2016-03-28;291(23):12358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice.
    Authors: Liu Z, Zhang N, Shao B, Panicker S, Fu J, McEver R
    J Biol Chem, 2015-12-02;291(3):1441-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  147. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
    Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
    J Immunol, 2015-09-21;195(9):4415-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension.
    Authors: Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, Davies M, Stoop A
    PLoS ONE, 2015-09-09;10(9):e0137065.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  149. Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
    Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
    J Immunol, 2015-09-09;195(8):3531-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death.
    Authors: Carlson N, Bellamkonda S, Schmidt L, Redd J, Huecksteadt T, Weber L, Davis E, Wood B, Maruyama T, Rose J
    J Neuroinflammation, 2015-05-23;12(0):101.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion.
    Authors: Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, Sun K, Sun H, Wang H, Zhang Z, Zhang B, Sheng C, Wang H, Hu P
    Cell Res, 2015-05-15;25(6):655-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells.
    Authors: Guay C, Menoud V, Rome S, Regazzi R
    Cell Commun Signal, 2015-03-19;13(0):17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
    Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
    Nat Med, 2015-03-16;21(4):363-72.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  154. Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression.
    Authors: Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell R, Spilianakis C
    Proc Natl Acad Sci U S A, 2015-03-13;112(13):E1577-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Mitochondria and NADPH oxidases are the major sources of TNF-alpha/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells.
    Authors: Babu D, Leclercq G, Goossens V, Vanden Berghe T, Van Hamme E, Vandenabeele P, Lefebvre R
    Cell Signal, 2015-02-26;27(6):1141-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
    Authors: Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, Fung H, Albrecht S, Alexandropoulos K, McCauley D, Chook Y, Kuhlmann T, Kidd G, Shacham S, Casaccia P
    Nat Neurosci, 2015-02-23;18(4):511-20.
    Species: Mouse
    Sample Types: Whole Organism
    Applications: In Vivo
  157. ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.
    Authors: Hennigar S, Seo Y, Sharma S, Soybel D, Kelleher S
    Sci Rep, 2015-01-26;5(0):8033.
    Species: Mouse
    Sample Types: Whole Organism
    Applications: In Vivo
  158. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
    Authors: Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, West J, Hansen K, Horan K, Jakobsen M, O'Hare P, Adler H, Sun R, Ploegh H, Damania B, Upton J, Fitzgerald K, Paludan S
    J Immunol, 2015-01-16;194(4):1819-31.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  159. The generation of neutrophils in the bone marrow is controlled by autophagy.
    Authors: Rozman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H
    Cell Death Differ, 2014-10-17;22(3):445-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Transforming growth factor beta-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling.
    Authors: Li L, Chen Y, Doan J, Murray J, Molkentin J, Liu Q
    Circulation, 2014-10-02;130(24):2162-72.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
    Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
    Elife, 2014-09-16;3(0):e02809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Inhibition of Ca2+-independent phospholipase A2beta (iPLA2beta) ameliorates islet infiltration and incidence of diabetes in NOD mice.
    Authors: Bone R, Gai Y, Magrioti V, Kokotou M, Ali T, Lei X, Tse H, Kokotos G, Ramanadham S
    Diabetes, 2014-09-11;64(2):541-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
    Authors: Kowalewska P, Patrick A, Fox-Robichaud A
    PLoS ONE, 2014-09-03;9(9):e104537.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  164. HDAC inhibitor-mediated beta-cell protection against cytokine-induced toxicity is STAT1 Tyr701 phosphorylation independent.
    Authors: Dahllof M, Christensen D, Harving M, Wagner B, Mandrup-Poulsen T, Lundh M
    J Interferon Cytokine Res, 2014-07-25;35(1):63-70.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.
    Authors: McComb S, Cessford E, Alturki N, Joseph J, Shutinoski B, Startek J, Gamero A, Mossman K, Sad S
    Proc Natl Acad Sci U S A, 2014-07-21;111(31):E3206-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Free fatty acids and IL-6 induce adipocyte galectin-3 which is increased in white and brown adipose tissues of obese mice.
    Authors: Krautbauer S, Eisinger K, Hader Y, Buechler C
    Cytokine, 2014-07-17;69(2):263-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014-07-14;5(0):4436.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014-07-10;9(7):e101937.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  169. beta-Arrestin 2 negatively regulates Toll-like receptor 4 (TLR4)-triggered inflammatory signaling via targeting p38 MAPK and interleukin 10.
    Authors: Li H, Hu D, Fan H, Zhang Y, LeSage G, Caudle Y, Stuart C, Liu Z, Yin D
    J Biol Chem, 2014-07-10;289(33):23075-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2alpha.
    Authors: Grabiner M, Fu Z, Wu T, Barry K, Schwarzer C, Machen T
    J Immunol, 2014-07-02;193(3):1459-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
    Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
    Autophagy, 2014-05-14;10(7):1301-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts.
    Authors: Le Goff B, Singbrant S, Tonkin B, Martin T, Romas E, Sims N, Walsh N
    Cytokine, 2014-04-22;68(2):101-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-alpha and interleukin-1beta but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain.
    Authors: Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, Hoshino M, Imamura T, Akiyama C, Yasuhara R, Mishima K, Maruyama T, Kohda C, Tanaka K, Potempa J, Yasuda H, Baba K, Kamijo R
    J Biol Chem, 2014-04-22;289(22):15621-30.
    Species: Bacteria - Porphyromonas gingivalis, Mouse
    Sample Types: Protein, Whole Cells
    Applications: Bioassay, Degradation
  174. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
    Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
    Nature, 2014-04-13;509(7499):235-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Matrix metalloproteinase-9 deficiency attenuates diabetic nephropathy by modulation of podocyte functions and dedifferentiation.
    Authors: Li S, Huang P, Yang A, Tarng D, Yang W, Lin C, Chen J, Schmid-Schonbein G, Lin S
    Kidney Int, 2014-03-26;86(2):358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
    Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
    J Biol Chem, 2014-03-19;289(18):12578-92.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions.
    Authors: Duong S, Condotta S, Rai D, Martin M, Griffith T, Badovinac V
    J Immunol, 2014-03-19;192(8):3618-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. IFN-gamma or IFN-alpha ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.
    Authors: Tamiya H, Terao M, Takiuchi T, Nakahara M, Sasaki Y, Katayama I, Yoshikawa H, Iwai K
    J Immunol, 2014-03-14;192(8):3793-804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
    Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
    Nat Med, 2014-03-02;20(4):377-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Is SIRT2 required for necroptosis?
    Authors: Newton K, Hildebrand J, Shen Z, Rodriguez D, Alvarez-Diaz S, Petersen S, Shah S, Dugger D, Huang C, Auwerx J, Vandenabeele P, Green D, Ashkenazi A, Dixit V, Kaiser W, Strasser A, Degterev A, Silke J
    Nature, 2014-02-27;506(7489):E4-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  181. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014-02-20;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-alpha secretion.
    Authors: Berta T, Park C, Xu Z, Xie R, Liu T, Lu N, Liu Y, Ji R
    J Clin Invest, 2014-02-17;124(3):1173-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis.
    Authors: Holzscheiter M, Layland L, Loffredo-Verde E, Mair K, Vogelmann R, Langer R, Wagner H, Prazeres da Costa C
    Clin Exp Immunol, 2014-02-01;175(2):246-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Endothelial cell-derived chemerin promotes dendritic cell transmigration.
    Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
    J Immunol, 2014-01-27;192(5):2366-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via beta2 integrins (CD11/CD18).
    Authors: Weckbach L, Gola A, Winkelmann M, Jakob S, Groesser L, Borgolte J, Pogoda F, Pick R, Pruenster M, Muller-Hocker J, Deindl E, Sperandio M, Walzog B
    Blood, 2014-01-23;123(12):1887-96.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  186. The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
    Authors: McMichael B, Scherer K, Franklin N, Lee B
    PLoS ONE, 2014-01-23;9(1):e87402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Unbiased expression mapping identifies a link between the complement and cholinergic systems in the rat central nervous system.
    Authors: Lindblom R, Strom M, Heinig M, Al Nimer F, Aeinehband S, Berg A, Dominguez C, Vijayaraghavan S, Zhang X, Harnesk K, Zelano J, Hubner N, Cullheim S, Darreh-Shori T, Diez M, Piehl F
    J Immunol, 2013-12-18;192(3):1138-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
    Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
    PLoS ONE, 2013-12-16;8(12):e84107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  189. Technical advance: monitoring the trafficking of neutrophil granulocytes and monocytes during the course of tissue inflammation by noninvasive 19F MRI.
    Authors: Temme S, Jacoby C, Ding Z, Bonner F, Borg N, Schrader J, Flogel U
    J Leukoc Biol, 2013-12-06;95(4):689-97.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  190. TGF-beta promotes immune responses in the presence of mesenchymal stem cells.
    Authors: Xu C, Yu P, Han X, DU L, Gan J, Wang Y, Shi Y
    J Immunol, 2013-11-29;192(1):103-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Optineurin insufficiency impairs IRF3 but not NF-kappaB activation in immune cells.
    Authors: Munitic I, Giardino Torchia M, Meena N, Zhu G, Li C, Ashwell J
    J Immunol, 2013-11-15;191(12):6231-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  192. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
    Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
    Mucosal Immunol, 2013-11-13;7(4):818-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation.
    Authors: Leslie K, Song G, Barrick S, Wehbi V, Vilardaga J, Bauer P, Bisello A
    J Biol Chem, 2013-11-06;288(51):36426-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
    Authors: Kook, S, Zhan, X, Cleghorn, W M, Benovic, J L, Gurevich, V V, Gurevich, E V
    Cell Death Differ, 2013-10-18;21(1):172-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  195. TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis.
    Authors: Xu C, Chang A, Hack B, Eadon M, Alper S, Cunningham P
    Kidney Int, 2013-07-31;85(1):72-81.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  196. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
    Authors: Steelman A, Smith R, Welsh C, Li J
    J Biol Chem, 2013-07-08;288(33):23776-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Enhancement of inflammatory protein expression and nuclear factor Kappab (NF-Kappab) activity by trichostatin A (TSA) in OP9 preadipocytes.
    Authors: Sato T, Kotake D, Hiratsuka M, Hirasawa N
    PLoS ONE, 2013-03-26;8(3):e59702.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-delta.
    Authors: Do-Umehara H, Chen C, Urich D, Zhou L, Qiu J, Jang S, Zander A, Baker M, Eilers M, Sporn P, Ridge K, Sznajder J, Budinger G, Mutlu G, Lin A, Liu J
    Nat Immunol, 2013-03-24;14(5):461-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.
    Authors: Yoshimura T, Howard O, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim J, Wang J
    PLoS ONE, 2013-03-18;8(3):e58791.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013-03-13;190(8):4196-204.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response.
    Authors: Dearth C, Goh Q, Marino J, Cicinelli P, Torres-Palsa M, Pierre P, Worth R, Pizza F
    PLoS ONE, 2013-03-11;8(3):e58486.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  202. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
    Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
    Eur J Immunol, 2013-03-06;43(4):979-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
    Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
    J Biol Chem, 2013-03-04;288(18):12699-711.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli.
    Authors: Sheng Y, Triyana S, Wang R, Das I, Gerloff K, Florin T, Sutton P, McGuckin M
    Mucosal Immunol, 2012-11-14;6(3):557-68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  205. Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion.
    Authors: Shrestha N, Bahnan W, Wiley D, Barber G, Fields K, Schesser K
    J Biol Chem, 2012-07-02;287(34):28738-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
    Authors: Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S
    J. Exp. Med., 2012-05-21;209(6):1219-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  208. Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced toll-like receptor signaling.
    Authors: Bradley LM, Douglass MF, Chatterjee D, Akira S, Baaten BJ
    PLoS Pathog., 2012-04-05;8(4):e1002641.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice.
    Authors: Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algul H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP
    J. Clin. Invest., 2012-04-02;122(5):1758-63.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  210. Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression.
    Authors: Liu N, Meng Z, Lou G, Zhou W, Wang X, Zhang Y, Zhang L, Liu X, Yen Y, Lai L, Forman BM, Xu Z, Xu R, Huang W
    Mol. Endocrinol., 2012-04-02;26(5):775-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
    Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
    PLoS ONE, 2012-02-29;7(2):e32125.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
    Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    Am. J. Pathol., 2011-10-26;180(1):365-74.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  213. IL-22 Is Produced by Innate Lymphoid Cells and Limits Inflammation in Allergic Airway Disease.
    Authors: Taube C, Tertilt C, Gyulveszi G, Dehzad N, Kreymborg K, Schneeweiss K, Michel E, Reuter S, Renauld JC, Arnold-Schild D, Schild H, Buhl R, Becher B
    PLoS ONE, 2011-07-18;6(7):e21799.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011-04-24;12(6):568-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. IL-17A and TNF-alpha Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro.
    Authors: Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
    J. Immunol., 2011-01-31;186(5):3197-205.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  216. TNFR2 interposes the proliferative and NF-kappaB-mediated inflammatory response by podocytes to TNF-alpha.
    Authors: Bruggeman LA, Drawz PE, Kahoud N, Lin K, Barisoni L, Nelson PJ
    Lab. Invest., 2011-01-10;91(3):413-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo.
    Authors: Petri B, Kaur J, Long EM, Li H, Parsons SA, Butz S, Phillipson M, Vestweber D, Patel KD, Robbins SM, Kubes P
    Blood, 2010-10-28;117(3):942-52.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  218. ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
    Authors: Le Gall SM, Maretzky T, Issuree PD, Niu XD, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP
    J. Cell. Sci., 2010-10-27;123(0):3913-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay, ELISA (Standard)
  219. Tumor necrosis factor-alpha regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells.
    Authors: Bhatnagar S, Panguluri SK, Gupta SK, Dahiya S, Lundy RF, Kumar A
    PLoS ONE, 2010-10-12;5(10):e13262.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
    Authors: Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE
    J. Immunol., 2010-09-10;185(7):4354-62.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  221. Vitamin D3 upregulated protein 1 suppresses TNF-alpha-induced NF-kappaB activation in hepatocarcinogenesis.
    Authors: Kwon HJ, Won YS, Suh HW, Jeon JH, Shao Y, Yoon SR, Chung JW, Kim TD, Kim HM, Nam KH, Yoon WK, Kim DG, Kim JH, Kim YS, Kim DY, Kim HC, Choi I
    J. Immunol., 2010-09-08;185(7):3980-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  222. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis.
    Authors: Chou RC, Kim ND, Sadik CD
    Immunity, 2010-08-27;33(2):266-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  223. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
    Authors: Suzuki K, Maruya M, Kawamoto S
    Immunity, 2010-07-23;33(1):71-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.
    Authors: Murthy A, Defamie V, Smookler DS
    J. Clin. Invest., 2010-07-12;120(8):2731-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.
    Authors: Tiller G, Laumen H, Fischer-Posovszky P, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H
    Int J Obes (Lond), 2010-06-15;35(2):208-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis.
    Authors: Bixel MG, Li H, Petri B, Khandoga AG, Khandoga A, Zarbock A, Wolburg-Buchholz K, Wolburg H, Sorokin L, Zeuschner D, Maerz S, Butz S, Krombach F, Vestweber D
    Blood, 2010-05-17;116(7):1172-84.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  227. RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo.
    Authors: Frommhold D, Kamphues A, Hepper I, Pruenster M, Lukic IK, Socher I, Zablotskaya V, Buschmann K, Lange-Sperandio B, Schymeinsky J, Ryschich E, Poeschl J, Kupatt C, Nawroth PP, Moser M, Walzog B, Bierhaus A, Sperandio M
    Blood, 2010-04-20;116(5):841-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  228. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010-03-24;184(0):5263-70.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  229. Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.
    Authors: Mueller H, Stadtmann A, Van Aken H, Hirsch E, Wang D, Ley K, Zarbock A
    Blood, 2010-02-18;115(15):3118-27.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  230. ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway.
    Authors: Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, Di Polo A, Barker PA
    Proc. Natl. Acad. Sci. U.S.A., 2010-02-03;107(8):3817-22.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  231. Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability.
    Authors: Blanchet MR, Gold M, Maltby S, Bennett J, Petri B, Kubes P, Lee DM, McNagny KM
    J. Immunol., 2009-12-28;184(3):1292-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  232. Epifluorescence intravital microscopy of murine corneal dendritic cells.
    Authors: Lee EJ, Rosenbaum JT, Planck SR
    Invest. Ophthalmol. Vis. Sci., 2009-12-10;51(4):2101-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  233. Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
    Authors: Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K
    J. Bone Miner. Res., 2009-12-01;24(12):2056-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
    Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
    J. Immunol., 2009-10-19;183(10):6135-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  235. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2009-10-07;3(1):40-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. A lymphotoxin-driven pathway to hepatocellular carcinoma.
    Authors: Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M
    Cancer Cell, 2009-10-06;16(4):295-308.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  237. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
    Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
    Nat. Med., 2009-09-20;15(10):1170-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice.
    Authors: Wahl EC, Aronson J, Liu L, Skinner RA, Miller MJ, Cockrell GE, Fowlkes JL, Thrailkill KM, Bunn RC, Ronis MJ, Lumpkin CK
    Bone, 2009-09-17;46(2):410-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  239. A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice.
    Authors: Page K, Ledford JR, Zhou P, Wills-Karp M
    J. Immunol., 2009-08-10;183(5):3400-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Primed CD8(+) T-cell responses to allogeneic endothelial cells are controlled by local complement activation.
    Authors: Raedler H, Yang M, Lalli PN
    Am. J. Transplant., 2009-06-26;9(8):1784-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  241. TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant.
    Authors: Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Hiroi T, Itoh N, Kawai Y, Mayumi T, Kamada H, Tsunoda S, Tsutsumi Y
    Biochem. Biophys. Res. Commun., 2009-05-04;384(3):296-300.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  242. Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury.
    Authors: Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY, Frenette PS
    Nat. Med., 2009-03-22;15(4):384-91.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  243. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009-03-13;11(4):524-30.
    Applications: ELISA (Standard)
  244. Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells.
    Authors: Moser M, Bauer M, Schmid S, Ruppert R, Schmidt S, Sixt M, Wang HV, Sperandio M, Fassler R
    Nat. Med., 2009-02-22;15(3):300-5.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  245. Induction of hepatitis by JNK-mediated expression of TNF-alpha.
    Authors: Das M, Sabio G, Jiang F, Rincon M, Flavell RA, Davis RJ
    Cell, 2009-01-23;136(2):249-60.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  246. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
    Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
    J. Exp. Med., 2009-01-12;206(1):69-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  247. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
    Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
    Arthritis Rheum., 2008-11-01;58(11):3510-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2.
    Authors: Audoy-Remus J, Richard JF, Soulet D, Zhou H, Kubes P, Vallieres L
    J. Neurosci., 2008-10-08;28(41):10187-99.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  249. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
    Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
    J. Invest. Dermatol., 2008-10-02;129(3):650-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  250. An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation.
    Authors: Shigeta A, Matsumoto M, Tedder TF, Lowe JB, Miyasaka M, Hirata T
    Blood, 2008-09-25;112(13):4915-23.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  251. PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.
    Authors: Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K
    J. Exp. Med., 2008-09-15;205(10):2339-47.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  252. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
    Authors: Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, LaCasse EC, Waring J, Korneluk RG
    Proc. Natl. Acad. Sci. U.S.A., 2008-08-12;105(33):11778-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. XIAP regulates intracellular ROS by enhancing antioxidant gene expression.
    Authors: Resch U, Schichl YM, Sattler S, de Martin R
    Biochem. Biophys. Res. Commun., 2008-08-08;375(1):156-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc.
    Authors: Yakubenia S, Frommhold D, Scholch D, Hellbusch CC, Korner C, Petri B, Jones C, Ipe U, Bixel MG, Krempien R, Sperandio M, Wild MK
    Blood, 2008-06-09;112(4):1472-81.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  255. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
    Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
    Exp. Hematol., 2008-05-01;36(5):545-558.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  256. Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
    Authors: Norman MU, Zbytnuik L, Kubes P
    Eur. J. Immunol., 2008-05-01;38(5):1368-80.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  257. Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance.
    Authors: Ashare A, Nymon AB, Doerschug KC, Morrison JM, Monick MM, Hunninghake GW
    Am. J. Respir. Crit. Care Med., 2008-04-24;178(2):149-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo.
    Authors: Kerfoot SM, Andonegui G, Bonder CS, Liu L
    Am. J. Physiol. Heart Circ. Physiol., 2008-04-18;294(6):H2524-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  259. TNF receptor independent activation of the cytomegalovirus major immediate early enhancer in response to transplantation.
    Authors: Zhang Z, Kim SJ, Varghese T, Thomas G, Hummel M, Abecassis M
    Transplantation, 2008-04-15;85(7):1039-45.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  260. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008-04-03;125(2):272-9.
    Applications: ELISA (Standard)
  261. A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI.
    Authors: von Zur Muhlen C, Sibson NR, Peter K, Campbell SJ, Wilainam P, Grau GE, Bode C, Choudhury RP, Anthony DC
    J. Clin. Invest., 2008-03-01;118(3):1198-207.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  262. The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages.
    Authors: Zhang J, Wu Y, Zhang Y, LeRoith D, Bernlohr DA, Chen X
    Mol. Endocrinol., 2008-02-21;22(6):1416-26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007-12-21;111(8):4096-105.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  264. Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
    Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
    Nature, 2007-12-06;450(7171):825-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells.
    Authors: Kaminski A, Ma N, Donndorf P, Lindenblatt N, Feldmeier G, Ong LL, Furlani D, Skrabal CA, Liebold A, Vollmar B, Steinhoff G
    Lab. Invest., 2007-11-26;88(1):58-69.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  266. Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice.
    Authors: Narita M, Shimamura M, Imai S, Kubota C, Yajima Y, Takagi T, Shiokawa M, Inoue T, Suzuki M, Suzuki T
    Neuroscience, 2007-11-12;152(2):477-86.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  267. IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis.
    Authors: Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, Liew FY, Kimber I, Groves RW
    J. Leukoc. Biol., 2007-11-05;83(2):361-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  268. Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate.
    Authors: Zetterstrom CK, Jiang W, Wahamaa H, Ostberg T, Aveberger AC, Schierbeck H, Lotze MT, Andersson U, Pisetsky DS, Erlandsson Harris H
    J. Leukoc. Biol., 2007-10-03;83(1):31-8.
    Applications: ELISA (Standard)
  269. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
    Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
    J. Immunol., 2007-08-01;179(3):1872-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo.
    Authors: Liu L, Puri KD, Penninger JM, Kubes P
    Blood, 2007-05-08;110(4):1191-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  271. Interferon-gamma synergises with tumour necrosis factor and lymphotoxin-alpha to enhance the mRNA and protein expression of adhesion molecules in mouse brain endothelial cells.
    Authors: Weiser S, Miu J, Ball HJ, Hunt NH
    Cytokine, 2007-04-06;37(1):84-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  272. TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine.
    Authors: Dogra C, Changotra H, Wedhas N, Qin X, Wergedal JE, Kumar A
    FASEB J., 2007-02-21;21(8):1857-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Dickkopf-1 is a master regulator of joint remodeling.
    Authors: Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G
    Nat. Med., 2007-01-21;13(2):156-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.
    Authors: Robertson SA, Care AS, Skinner RJ
    Biol. Reprod., 2007-01-10;76(5):738-48.
    Applications: ELISA (Standard)
  275. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
    Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
    J. Immunol., 2006-12-15;177(12):8650-7.
    Applications: ELISA (Standard)
  276. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006-12-01;177(11):7665-72.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  277. TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
    Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
    J. Immunol., 2006-12-01;177(11):7980-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  278. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006-11-20;203(12):2763-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
    Authors: Penido C, Conte FP, Chagas MS, Rodrigues CA, Pereira JF, Henriques MG
    Inflamm. Res., 2006-11-01;55(11):457-64.
    Applications: ELISA (Standard)
  280. Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
    Authors: Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R
    Circulation, 2006-09-25;114(14):1504-11.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  281. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors.
    Authors: Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, Forsman M, Bystrom M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK
    Infect. Immun., 2006-09-18;74(12):6730-8.
    Applications: ELISA (Standard)
  282. Suppressive effect of simvastatin on interferon-beta-induced expression of CC chemokine ligand 5 in microglia.
    Authors: Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takayama-Ito M, Kurane I
    Neurosci. Lett., 2006-09-15;407(3):205-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1246-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4).
    Authors: Ramos CD, Fernandes KS, Canetti C, Teixeira MM, Silva JS, Cunha FQ
    Eur. J. Immunol., 2006-08-01;36(8):2025-34.
    Applications: ELISA (Standard)
  285. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
    Authors: Osuchowski MF, Welch K, Siddiqui J, Remick DG
    J. Immunol., 2006-08-01;177(3):1967-74.
    Applications: ELISA (Standard)
  286. Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.
    Authors: Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M
    Proc. Natl. Acad. Sci. U.S.A., 2006-07-24;103(31):11784-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury.
    Authors: Gao H, Hoesel LM, Guo RF, Rancilio NJ, Sarma JV, Ward PA
    J. Immunol., 2006-07-01;177(1):612-20.
    Applications: ELISA (Standard)
  288. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
    Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
    J Ethnopharmacol, 2006-03-10;106(3):418-24.
    Applications: ELISA (Standard)
  289. TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
    Authors: Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A
    Arthritis Res. Ther., 2006-01-01;8(5):R146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury.
    Authors: Mendez MP, Morris SB, Wilcoxen S, Greeson E, Moore B, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L962-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
    Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
    Mol. Cell. Neurosci., 2005-11-16;31(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
    Authors: Costa SK, Yshii LM, Poston RN, Muscara MN, Brain SD
    J. Neuroimmunol., 2005-11-02;171(1):99-109.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  293. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
    Authors: Niederkofler V, Salie R, Arber S
    J. Clin. Invest., 2005-08-01;115(8):2180-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  294. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005-07-01;302(1):172-81.
    Applications: ELISA (Standard)
  295. Antibody-bound beta-amyloid precursor protein stimulates the production of tumor necrosis factor-alpha and monocyte chemoattractant protein-1 by cortical neurons.
    Authors: Gonzalez de Aguilar JL, Dupuis L, Larmet Y
    Neurobiol. Dis., 2005-06-01;19(1):129-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system.
    Authors: Ching S, He L, Lai W, Quan N
    Brain Behav. Immun., 2005-03-01;19(2):127-37.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  297. Selective macrophage suppression during sepsis.
    Authors: Ellaban E, Bolgos G, Remick D
    Cell. Immunol., 2005-02-26;231(1):103-11.
    Applications: ELISA (Standard)
  298. MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
    Authors: Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K
    J. Clin. Invest., 2005-02-01;115(2):459-67.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  299. IL-1 mediates TNF-induced osteoclastogenesis.
    Authors: Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL
    J. Clin. Invest., 2005-02-01;115(2):282-90.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  300. Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs.
    Authors: Simon CO, Seckert CK, Dreis D, Reddehase MJ, Grzimek NK
    J. Virol., 2005-01-01;79(1):326-40.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  301. Transcriptional profiling of lipopolysaccharide-induced acute lung injury.
    Authors: Jeyaseelan S, Chu HW, Young SK, Worthen GS
    Infect. Immun., 2004-12-01;72(12):7247-56.
    Applications: ELISA (Standard)
  302. HIV-1 Tat increases the adhesion of monocytes and T-cells to the endothelium in vitro and in vivo: implications for AIDS-associated vasculopathy.
    Authors: Matzen K, Dirkx AE, oude Egbrink MG, Speth C, Gotte M, Ascherl G, Grimm T, Griffioen AW, Sturzl M
    Virus Res., 2004-09-01;104(2):145-55.
    Species: Mouse
    Sample Types: Interstitial Fluid
    Applications: Bioassay
  303. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004-06-15;172(12):7408-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Thyrocytes isolated from autoimmune-diseased thyroids secrete soluble tumor necrosis factor-R1 that is related to their elevated protein kinase C activity.
    Authors: LaBue M, Colburn KK, Green LM
    Thyroid, 2004-04-01;14(4):249-62.
    Applications: Western Blot
  305. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node.
    Authors: Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I
    Proc. Natl. Acad. Sci. U.S.A., 2004-01-13;101(4):998-1003.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  306. Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation.
    Authors: Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K
    J. Immunol., 2003-12-01;171(11):6105-11.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  307. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation.
    Authors: Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN
    J. Biol. Chem., 2003-02-17;278(17):14677-87.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  308. Elevated levels of tumor necrosis factor alpha (TNF-alpha) in human immunodeficiency virus type 1-transgenic mice: prevention of death by antibody to TNF-alpha.
    Authors: De SK, Devadas K, Notkins AL
    J. Virol., 2002-11-01;76(22):11710-4.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  309. CD40 regulates the processing of NF-kappaB2 p100 to p52.
    Authors: Coope HJ, Atkinson PG, Huhse B, Belich M, Janzen J, Holman MJ, Klaus GG, Johnston LH, Ley SC
    EMBO J., 2002-10-15;21(20):5375-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
    Authors: Miller G, 107331, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
    Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1alpha and the NAMPT-NAD+ pathway, 2002-09-15;169(6):2875-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  311. Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy.
    Authors: Chaisson ML, Brooling JT, Ladiges W, Tsai S, Fausto N
    J. Clin. Invest., 2002-07-01;110(2):193-202.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  312. Modulation of marrow proliferation and chemosensitivity by tumor-produced cytokines from syngeneic pancreatic tumor lines.
    Authors: Blumenthal RD, Reising A, Leon E
    Clin. Cancer Res., 2002-05-01;8(5):1301-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
    Authors: Medvedev AE, Kopydlowski KM, Vogel SN
    J. Immunol., 2000-06-01;164(11):5564-74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. What is the difference between Recombinant Mouse TNF-alpha (aa 80-235) Protein (Catalog # 410-MT) & Recombinant Mouse TNF-alpha (aa 84-235) Protein (Catalog # 410-TRNC)?

    • The mature Recombinant Mouse TNF-alpha (aa 80-235) Protein (Catalog # 410-MT) begins at amino acid 80, whereas our truncated Recombinant Mouse TNF-alpha (aa 84-235) Protein (Catalog # 410-TRNC) begins at amino acid 84. The truncated protein (Catalog # 410-TRNC) has a higher degree of bioactivity in our in-house bioassay.

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Reviews for Recombinant Mouse TNF-alpha (aa 80-235) Protein

Average Rating: 4.8 (Based on 14 Reviews)

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By Anonymous on 06/18/2021
Application: Immunoassay Standard
Immunoassay Standard 410-MT
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 02/24/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Amruta Narayanappa on 11/27/2020
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Wuyi Wang on 10/28/2020
Application: Media additive for protein or antibody production
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Supriya Sen on 10/05/2020
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Zhenping Wang on 09/30/2020
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 03/06/2020
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 11/21/2019
Application: Media additive for protein or antibody production
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 02/20/2019
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By jayeeta giri on 01/28/2019
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 05/23/2016
Application: Binding assay/Protein-protein interaction
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 05/17/2016
Application: In vitro bioactivity in cell culture
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 05/12/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: Worked as expected.

Mouse (C57BL/6) naïve, SPF, stimulated with recombinant mouse TNF-alpha protein.

In vitro bioactivity in cell culture Recombinant Mouse TNF-alpha (aa 80-235) Protein 410-MT
Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 01/19/2016
Application: Immunoassay Standard