Home / Group I mGluR Antagonists / (RS)-MCPG disodium salt

(RS)-MCPG disodium salt

Catalog #: 3696
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3696/10
3696/50
(RS)-MCPG disodium salt | Group I mGluR Antagonists
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Description: Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)

Chemical Name: (RS)-α-Methyl-4-carboxyphenylglycine disodium salt

Purity: ≥99%

Product Details
Citations (2)
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Biological Activity

(RS)-MCPG disodium salt is a sodium salt of (RS)-MCPG, a non-selective group I/group II metabotropic glutamate receptor antagonist.

S-enantiomer also available.

Technical Data

M.Wt:
253.16
Formula:
C10H9NNa2O4
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Phenylglycine derivatives as metabotropic glutamate receptor antagonists.
    Collingridge and Watkins
    TiPS, 1994;15:333
  2. Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor Type 5 splice variants: comparison with mGluR1.
    Joly et al.
    J.Neurosci., 1995;15:3970
  3. Competitive antagonist at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine (CPG) and (RS)-α-methyl-4-carboxyphenylglycine (MCPG).
    Eaton et al.
    Eur.J.Pharmacol.Mol.Pharmacol.Sect., 1993;244:195

Product Datasheets

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Citations for (RS)-MCPG disodium salt

The citations listed below are publications that use Tocris products. Selected citations for (RS)-MCPG disodium salt include:

2 Citations: Showing 1 - 2

  1. Activation of Glutamate Transport Increases Arteriole Diameter in v ivo: Implications for Neurovascular Coupling.
    Authors: Hajime Et al.
    Front Cell Neurosci  2022;16:831061
  2. Distinct Modes of Presynaptic Inhibition of Cutaneous Afferents and Their Functions in Behavior.
    Authors: David D Et al.
    Neuron  2019;102:420-434.e8

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