SC 236

Catalog # Availability Size / Price Qty
3919/10
3919/50
SC 236 | CAS No. 170569-86-5 | Cyclooxygenase Inhibitors
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Description: Selective cyclooxygenase-2 (COX-2) inhibitor
Alternative Names: SC 58236

Chemical Name: 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide

Purity: ≥99%

Product Details
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Biological Activity

SC 236 is a selective COX-2 inhibitor (IC50 values are 0.005 and 17.8 μM for COX-2 and COX-1 respectively). Displays anti-inflammatory properties and potent antimetastatic activity against both experimental metastases and spontaneous metastases arising following primary tumor excision.

Technical Data

M.Wt:
401.79
Formula:
C16H11ClF3N3O2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
170569-86-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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