Simple Plex Human VEGFR1/Flt-1 Cartridge

Catalog #: SPCKB-PS-000384 Datasheet / COA / SDS

Discontinued - Please use SPCKB-PS-000540

Catalog #	Availability	Size / Price	Qty
SPCKB-PS-000384
SPCKA-PS-000384
SPCKC-PS-000384

Control Products Available

898108: Simple Plex Control for Human VEGFR1/Flt-1

Product Details

Supplemental Products

Reviews

Summary Recovery Linearity Product Datasheets Preparation and Storage Background Related Research Areas

Simple Plex Human VEGFR1/Flt-1 Cartridge Summary

Assay Type

Automated sandwich ELISA

Format

Microfluidic cartridge containing three Glass Nano Reactors (GNR)

Specificity

Natural and recombinant human VEGF R1.

Cross-reactivity

< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.

Interference

No significant interference observed with available related molecules.

*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.

Product Summary

Simple Plex assay for the detection of human VEGF R1 in serum and plasma (EDTA/Heparin)

Recovery

Recovery at three different spiked concentrations within the range of the assay was evaluated.

Linearity

Samples containing and/or spiked with high concentrations of human VEGF R1 were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay

Product Datasheets

Product Datasheet

COA

SDS

Preparation and Storage

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: VEGFR1/Flt-1

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Long Name:

Vascular Endothelial Growth Factor Receptor 1

Entrez Gene IDs:

2321 (Human); 14254 (Mouse)

Alternate Names:

EC 2.7.10; EC 2.7.10.1; FLT; FLT1; Flt-1; Fms-like tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor); FRT; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; Vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1