SU 3327

Catalog # Availability Size / Price Qty
3607/10
3607/50
SU 3327 | CAS No. 40045-50-9 | JNK/c-jun Inhibitors
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Description: Selective JNK inhibitor
Alternative Names: Halicin

Chemical Name: 5-[(5-Nitro-2-thiazolyl)thio]-1,3,4thiadiazol-2-amine

Purity: ≥99%

Product Details
Citations (4)
Reviews

Biological Activity

SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM). Inhibits the protein-protein interaction between JNK and JIP (IC50 = 239 nM). Displays selectivity over p38 MAPK and Akt. Restores insulin sensitivity in a mouse model of type-2 diabetes. Displays antibiotic activity against a range of bacteria including S.aureus, A.baumanni, C.difficile and M.tuberculosis.

Technical Data

M.Wt:
261.3
Formula:
C5H3N5O2S3
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
40045-50-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for SU 3327

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4 Citations: Showing 1 - 4

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