TAPI 2

Catalog # Availability Size / Price Qty
6013/1
TAPI 2
1 Image
Description: ADAM-17 (TACE) and MMP inhibitor

Chemical Name: N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide

Purity: ≥95%

Product Details
Citations (2)
Reviews

Biological Activity

TAPI 2 is an ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.

This product is typically reconstituted in water.

Technical Data

M.Wt:
415.54
Formula:
C19H37N5O5
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
689284-12-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for TAPI 2

The citations listed below are publications that use Tocris products. Selected citations for TAPI 2 include:

2 Citations: Showing 1 - 2

FAQs

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