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Taxol Janelia Fluor® 646

Catalog #: 6266
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6266/1
Taxol Janelia Fluor® 646 | Microtubule Probes
2 Images
Description: Red fluorescent taxol derivative; probe for microtubule staining; protocol available

Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate

Purity: ≥95%

Product Details
Citations (1)
Reviews
Biological Activity Scientific Data Technical Data Additional Information Product Datasheets Calculators

Biological Activity

Taxol Janelia Fluor® 646 is a red fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Taxol Janelia Fluor® 646 is fluorogenic: fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Excitation maximum = 655 nm; emission maximum = 671 nm.

For more information on how Taxol-Janelia Fluor® 646 may be used, see our protocol.

Scientific Data

Confocal Microscopy COS7 cells dye-labeled with Taxol Janelia Fluor 646 View Larger

Application of Taxol Janelia Fluor® 646, dye on COS7 cells. COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope. All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.

Optical Data for Taxol Janelia Fluor® 646

Taxol Janelia Fluor<sup>®</sup> 646 Dye Spectra
λabs 655 nm
λem 671 nm

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

Technical Data

M.Wt:
1403.62
Formula:
C79H82N4O18Si
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Product Datasheets

Reconstitution Calculator
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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Taxol Janelia Fluor® 646

The citations listed below are publications that use Tocris products. Selected citations for Taxol Janelia Fluor® 646 include:

1 Citation: Showing 1 - 1

  1. Capturing T lymphocytes' dynamic interactions with human neural cells using time-lapse microscopy.
    Authors: Lema&#238;tre Et al.
    Front.Immunol.  2021;12

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