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TCS 2002

Catalog #: 3869
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3869/10
3869/50
TCS 2002 | CAS No. 1005201-24-0 | GSK-3 Inhibitors
1 Image
Description: Potent GSK-3β inhibitor

Chemical Name: 2-Methyl-5-[3-[4-(methylsulfinyl)phenyl]-5-benzofuranyl]-1,3,4-oxadiazole

Purity: ≥99%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

TCS 2002 is a potent inhibitor of GSK-3β (IC50 = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in the mouse brain.

Technical Data

M.Wt:
338.38
Formula:
C18H14N2O3S
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1005201-24-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for TCS 2002

The citations listed below are publications that use Tocris products. Selected citations for TCS 2002 include:

1 Citation: Showing 1 - 1

  1. Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential.
    Authors: Bellio Et al.
    Sci Rep  2017;7:9702

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