TCS 2314

Catalog #: 3900 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
3900/10
3900/50

TCS 2314 | CAS No. 317353-73-4 | Integrin Receptor Inhibitors

1 Image

Description: α4β1 (VLA-4) antagonist

Chemical Name: 1-[[(3S)-4-[2-[4-[[[(2-Methylphenyl)amino]carbonyl]amino]phenyl]acety]l-3-morpholinyl]carbonyl]-4-piperidinediacetic acid

Purity: ≥98%

View All Products for Integrin Receptor Inhibitors

Product Details

Supplemental Products

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

TCS 2314 is an integrin very late antigen-4 (VLA-4; α₄β₁) antagonist (IC₅₀ = 4.4 nM). Blocks the activation of inflammatory cells.

Technical Data

M.Wt:

522.59

Formula:

C₂₈H₃₄N₄O₆

Solubility:

Soluble to 100 mM in DMSO and to 50 mM in ethanol

Purity:

≥98%

Storage:

Store at RT

CAS No:

317353-73-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist.
Muro et al.
J.Med.Chem., 2009;52:7974

Product Datasheets

COA view current batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for TCS 2314

There are currently no reviews for this product. Be the first to review TCS 2314 and earn rewards!

Have you used TCS 2314?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.