Home / Two-P Potassium Channels Activators / Terbinafine hydrochloride

Terbinafine hydrochloride

Catalog #: 6484
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6484/250
6484/50
Terbinafine hydrochloride | CAS No. 78628-80-5 | Two-P Potassium Channels Activators
1 Image
Description: Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase

Chemical Name: N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Terbinafine hydrochloride is a selective TASK3 activator (pEC50 = 6.2). Exhibits >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 (pIC50 = 5.69). Also antifungal; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.

Technical Data

M.Wt:
327.89
Formula:
C21H25N.HCl
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
78628-80-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Terbinafine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Terbinafine hydrochloride include:

1 Citation: Showing 1 - 1

  1. Modulation of TASK-1/3 channels at the hypoglossal motoneuron pool and effects on tongue motor output and responses to excitatory inputs in vivo: implications for strategies for obstructive sleep apnea pharmacotherapy.
    Authors: Richard L Et al.
    Sleep  2021;44

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Terbinafine hydrochloride

There are currently no reviews for this product. Be the first to review Terbinafine hydrochloride and earn rewards!

Have you used Terbinafine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.