Thrombin Receptor Agonist Peptide

Catalog #: 1185
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
1185/1

1 Image

Description: Causes platelet aggregation and secretion

Alternative Names: TRAP

Purity: ≥95%

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Product Details

Citations (2)

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Thrombin Receptor Agonist Peptide is an agonist at the thrombin receptor; causes platelet aggregation (EC₅₀ = 4 μM) and secretion.

Technical Data

M.Wt:

1739

Formula:

C₈₁H₁₁₈N₂₀O₂₃

Sequence:

SFLLRNPNDKYEPF

Solubility:

Soluble to 0.90 mg/ml in water

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

137339-65-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides.
Huang et al.
J.Biol.Chem., 1991;266:18435
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.
Vu et al.
Cell, 1991;64:1057
Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides.
Vassallo et al.
J.Biol.Chem., 1992;267:6081

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Citations for Thrombin Receptor Agonist Peptide

The citations listed below are publications that use Tocris products. Selected citations for Thrombin Receptor Agonist Peptide include:

2 Citations: Showing 1 - 2

A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p.
Authors: White Et al.
J Endocrinol 2015;194:142
Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.
Authors: Tripathi Et al.
Invest Ophthalmol Vis Sci 2014;55:3912

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