VasoTACS In Situ Apoptosis Detection Kit

TUNEL-based Apoptosis Detection Assay
Catalog # Availability Size / Price Qty
4826-30-K
VasoTACS In Situ Apoptosis Detection Kit_Rat Artery Tissue
1 Image
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Citations (5)
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VasoTACS In Situ Apoptosis Detection Kit Summary

VasoTACS® in situ

VasoTACS in situ (Catalog # 4826-30-K)
Visualization of Apoptotic Cells in Vascular Tissue
TIssue from the small artery of rat was formalin-fixed and paraffin-embedded following the initiation of drug-induced apoptosis. The tissue was processed according to the protocol in the VasoTACS Kit (Catalog # 4826-30-K) and visualized by light microscopy. Brown stained nuclei following counterstaining with Red Counterstain C indicated apoptotic cells. Data was provided courtesy of Dr. Jun Zhang, FDA.

Complete kits contain TACS BlueLabel, Red Counterstain C, and reagents necessary for generating positive controls. Kits are optimized for detection of apoptosis in vascular tissues.

Label: Biotin/Streptavidin-HRP/TACS Blue Label
Testing Format: Light Microscopy
Sample Type: Fixed cells, Embedded tissues, Frozen tissues
Size: 30 Tests


VasoTACS is a trademark of Trevigen, Inc.

Specifications

Shipping Conditions
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Storage
The product  requires storage at -20 to -70 °C, 2 - 8 °C, and room temperature.  Consult the product insert for specific storage temperatures. Do not use past expiration date.

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Scientific Data

Visualization of Apoptotic Cells in Vascular Tissue using the VasoTACS In Situ Apoptosis Detection Kit. TIssue from the small artery of rat was formalin-fixed and paraffin-embedded following the initiation of drug-induced apoptosis. The tissue was processed according to the protocol in the VasoTACS Kit (Catalog # 4826-30-K) and visualized by light microscopy. Brown stained nuclei following counterstaining with Red Counterstain C indicated apoptotic cells. Data was provided courtesy of Dr. Jun Zhang, FDA.

Citations for VasoTACS In Situ Apoptosis Detection Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis
    Authors: SM Krishna, J Li, Y Wang, CS Moran, A Trollope, P Huynh, R Jose, E Biros, J Ma, J Golledge
    Scientific Reports, 2021-08-31;11(1):17451.  2021-08-31
  2. Endothelial lipid phosphate phosphatase-3 deficiency that disrupts the endothelial barrier function is a modifier of cardiovascular development.
    Authors: Chatterjee I, Baruah J, Lurie E, Wary K
    Cardiovasc Res, 2016-04-28;111(1):105-18.  2016-04-28
  3. Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
    Authors: Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock I, Wort S
    Respir Res, 2015-09-18;16(0):114.  2015-09-18
  4. Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
    Authors: Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T
    J. Biol. Chem., 2009-08-12;284(42):29109-24.  2009-08-12
  5. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
    Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
    J. Clin. Invest., 2009-07-13;119(8):2257-70.  2009-07-13

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