Home / Bradykinin Receptor Antagonists / WIN 64338 hydrochloride

WIN 64338 hydrochloride

Catalog #: 1057
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1057/10
1057/50
WIN 64338 hydrochloride | CAS No. 163727-74-0 | Bradykinin Receptor Antagonists
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Description: Bradykinin B2 antagonist

Chemical Name: (S)-4-[2-[Bis(cyclohexylamino)methyleneamino]-3-(2-naphthalenyl)-1-oxopropylamino]benzyl tributyl phosphonium chloride hydrochloride

Product Details
Citations (1)
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Biological Activity

WIN 64338 hydrochloride is a the first potent, non-peptide, competitive bradykinin B2 receptor antagonist. In organ bath studies, WIN 64338 inhibits [3H]-bradykinin binding on guinea pig trachea with nanomolar affinity but is not active in the rabbit aorta (the classical bradykinin B1 preparation).

Technical Data

M.Wt:
783.95
Formula:
C45H68ClN4OP.HCl
Solubility:
Soluble to 75 mM in DMSO
Storage:
Desiccate at +4°C
CAS No:
163727-74-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for WIN 64338 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for WIN 64338 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction.
    Authors: Gross Et al.
    J Cardiovasc Pharmacol Ther  2013;18:38

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