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Y-27632 dihydrochloride

Catalog #: TB1254-GMP
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
TB1254-GMP/10
Y-27632 dihydrochloride | CAS No. 129830-38-2 | Rho-kinase Inhibitors
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Description: Y-27632 synthesized to cGMP guidelines

Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

Purity: ≥99%

Product Details
Citations (4)
Reviews
Biological Activity Technical Data Product Datasheets Calculators

Biological Activity

Y-27632 dihydrochloride is a Y-27632 synthesized to cGMP guidelines. Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

For more information about how Y-27632 may be used, please see our protocols: Transdifferentiating Fibroblasts into Neurons, Converting Fibroblasts into Cardiomyocytes (9C Cocktail), Accelerated Induction of Cortical Neurons from hiPSCs, Human iPSC-derived Myoblasts.

Research use only Y-27632 also available.

Current Good Manufacturing Practice (cGMP) is a harmonized set of guidelines that when implemented will ensure safe, reliable, consistent and quality-assured products. The Tocris range of cGMP small molecules is manufactured following relevant sections of ICH Q7 guidelines. Our highly skilled team has full control over the cGMP process, meaning we can ensure: a quality-assured manufacturing system, batch-to-batch consistency, consistent supply, traceability from starting material to final product, and animal-free production. Find out more about the Tocris range of cGMP compounds.

Technical Data

M.Wt:
320.26
Formula:
C14H21N3O.2HCl
Purity:
≥99%
Storage:
Store at RT
CAS No:
129830-38-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
This product is intended for research use or further manufacturing only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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Citations for Y-27632 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Y-27632 dihydrochloride include:

4 Citations: Showing 1 - 4

  1. Generation of an iPSC line (SMCPGi001-A) from a patient with Bain type X-linked mental retardation syndrome carrying HNRNPH2 gene mutation.
    Authors: Ma Et al.
    Stem Cell Res.  2021;57:102571
  2. Establishment of an induced pluripotent stem cell line (ZJSHi001-A) from a patient with epileptic encephalopathy carrying KCNB1 Glu330Asp mutation.
    Authors: Guo Et al.
    Stem Cell Res.  2021;52:102224
  3. An optimized protocol for the generation of midbrain dopamine neurons under defined conditions.
    Authors: Gantner Et al.
    STAR Protoc.  2020;1:100065
  4. The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest.
    Authors: Duman Et al.
    Elife  2019;8

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