Zolantidine dimaleate

Catalog #: 1070
1 Citation Datasheet / COA / SDS

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Zolantidine dimaleate | CAS No. 104076-39-3 | Histamine H2 Receptor Antagonists

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Description: Potent, centrally active H2 antagonist

Chemical Name: N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2-benzothiazolamine dimaleate

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Product Details

Citations (1)

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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Zolantidine dimaleate is a a potent, selective and brain penetrating H₂ receptor antagonist.

Technical Data

M.Wt:

613.68

Formula:

C₂₂H₂₇N₃OS.2C₄H₄O₄

Solubility:

Soluble to 100 mM in water

Storage:

Desiccate at +4°C

CAS No:

104076-39-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:

Sold with the permission of GlaxoSmithKline

Background References

Zolantidine (SK&F 95282) is a potent selective brain penetrating histamine H₂-receptor antagonist.
Calcutt et al.
Br.J.Pharmacol., 1988;93:69
Activity of the new histamine H₂-receptor antagonist zolantidine at cardiac and gastric H₂ receptors.
Coruzzi et al.
Pharmacology, 1994;48:69
Cardiac and gastric effects of histamine H₂ receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity.
Coruzzi et al.
Br.J.Pharmacol., 1996;118:1813

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Citation for Zolantidine dimaleate

The citations listed below are publications that use Tocris products. Selected citations for Zolantidine dimaleate include:

1 Citation: Showing 1 - 1

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.
Authors: Porter Et al.
J Pharmacol Exp Ther 2005;315:711

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