Additional Reduction/Oxidation (Redox) Enzymes
Due to the nature of redox reactions, all enzymes that catalyze redox reactions can theoretically modulate oxidative stress. While numerous redox enzymes have been shown in the literature to directly promote or inhibit oxidative stress, additional redox enzymes may also contribute to oxidative stress, particularly under pathological conditions.
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Dehydrogenases/Reductases
- 11 beta-HSD1
- 11 beta-HSD2
- 15-PGDH/HPGD
- 17 beta-HSD1/HSD17B1
- 17 beta-HSD14/HSD17B14
- Aldehyde Dehydrogenase 1-A1/ALDH1A1
- Aldehyde Dehydrogenase 3-A1/ALDH3A1
- ALDH1A2
- ALDH2
- Aldo-keto Reductase 1B10/AKR1B10
- Aldo-keto Reductase 1C1/AKR1C1
- Aldo-keto Reductase 1C3/AKR1C3
- Aldo-keto Reductase 1C4/AKR1C4
- Biliverdin Reductase A/BLVRA
- Biliverdin Reductase B/BLVRB
- DECR1
- Dehydrogenase Activators
- Dehydrogenase Inhibitors
- DHODH
- DHODH Inhibitors
- Dihydrofolate Reductase/DHFR
- Dihydrolipoamide Dehydrogenase/DLD
- ERO1L alpha
- G6PD
- GAPDH
- GAPDH-2
- GILT/IFI30
- GLUD1/GLUD2
- Glutamate Dehydrogenase 1/GLUD1
- Glutamate Dehydrogenase 2/GLUD2
- Glutathione Reductase
- GPD1
- GPD1L
- HHIPL1
- HMG-CoA Reductase/HMGCR
- IMP Dehydrogenase 1/IMPDH1
- IMP Dehydrogenase 2/IMPDH2
- Isocitrate Dehydrogenase 1/IDH1
- Isocitrate Dehydrogenase 2/IDH2
- Lactate Dehydrogenase A/LDHA
- Lactate Dehydrogenase A/LDHA Inhibitors
- Lactate Dehydrogenase B/LDHB
- NQO-1
- NQO-2
- OGDH
- PDHX
- 6-Phosphogluconate Dehydrogenase/PGD
- PHGDH
- POR/Cytochrome P450 Reductase
- QDPR
- SCD-1
- SCD5
- STEAP1
- STEAP2
- STEAP3/TSAP6
- Thioredoxin Reductase 1/TRXR1
- Thioredoxin Reductase 2/TRXR2
- WWOX
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Oxygenases/Hydroxylases
- ABP1/AOC1
- Aldehyde Oxidase 1/AOX1
- AOC2
- COX-1
- COX-2
- COX4
- COX4-I1
- COX4-I2
- Cyclooxygenase Inhibitors
- Dopamine beta-Hydroxylase
- EGLN2/PHD1
- EGLN3/PHD3
- EGLN1/PHD2
- Epoxide Hydrolase 1/EPHX1
- Epoxide Hydrolase 2/EPHX2
- GCHFR
- GFER/ALR
- Hematopoietic Prostaglandin D Synthase/HPGDS
- Hydroxyacid Oxidase-1/HAO-1
- Hydroxylase Inhibitors
- IDO2
- Indoleamine 2,3-dioxygenase/IDO
- JMJD6/PSR
- Kynurenine 3-Monooxygenase/KMO
- Lipoxygenase Inhibitors
- 5-Lipoxygenase
- LOXL1
- LOXL4
- Lysine Hydroxylase 2/PLOD2
- Lysyl Oxidase Homolog 2/LOXL2
- Lysyl Oxidase Homolog 3/LOXL3
- MAO-A
- Monoamine Oxidase (MAO) Inhibitors
- NADPH Oxidase Inhibitors
- Nox4
- NOX1
- Other Oxidase/Oxygenase Compounds
- PAM
- Protein Disulfide Isomerase/P4HB
- QSOX1/Quiescin Q6
- TDO2
- Tryptophan Hydroxylase
- Tryptophan Hydroxylase 1/TPH-1
- Tryptophan Hydroxylase 2
- Tyrosine Hydroxylase
- VAP-1/AOC3