Transcription Factors and Regulators
Signal transduction often culminates in the activation of transcription factors, a specialized subset of proteins capable of interacting with DNA and either up- or down-regulating the transcription of genes. They are highly regulated with respect to location (cytoplasmic vs. nuclear), stabilization, and post-translational modification.
- Basic Helix-Loop-Helix (bHLH) Transcription Factors
- Basic Leucine Zipper (bZIP) Transcription Factors
- ETS Family Transcription Factors
- Forkhead Domain Transcription Factors
- GATA Transcription Factors
- HIF Transcription Factors
- High Mobility Group (HMG) Transcription Factors
- Homeodomain (Hox) Transcription Factors
- Immunoglobulin-Like Domain Transcription Factors
- Interferon-Regulatory Factor Transcription Factors
- Kruppel-Like Transcription Factors
- Paired Box Transcription Factors
- Smad Transcription Factors
- Other Transcription Factors
- Transcriptional Chromatin Remodeling
- Transcriptional Co-Activators
- Transcriptional Co-Repressors
- Other Transcriptional Regulators
- Other Zinc Finger Transcription Factors