Recombinant Human IL-1 beta/IL-1F2 Protein

GMP Version Available: 201-GMP
GMP

Carrier Free

Catalog # Availability Size / Price Qty
201-LB-005/CF
201-LB-025/CF
201-LB-500/CF
201-LB-100/CF
201-LB-010/CF
201-LB-01M/CF

With Carrier

Catalog # Availability Size / Price Qty
201-LB-005
201-LB-025
201-LB-010
201-LB-100
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Recombinant Human IL-1 beta/IL-1F2 Protein Bioactivity
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Product Details
Citations (549)
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Recombinant Human IL-1 beta/IL-1F2 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED50 for this effect is <12 pg/mL.
Source
E. coli-derived human IL-1 beta/IL-1F2 protein
Ala117-Ser269
Accession #
N-terminal Sequence
Analysis
Ala117 & Pro118
Predicted Molecular Mass
17 kDa
SDS-PAGE
17 kDa, reducing conditions

Product Datasheets

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201-LB (with carrier)

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201-LB/CF (carrier free)

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

201-LB

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 50-200 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. *The 1 mg pack size (01M) is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
*The 1 mg pack size (01M) can be stored for 1 month at 2 to 8 °C under sterile conditions after opening.

201-LB/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Reconstitution Reconstitute at 50-200 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:


Scientific Data

Bioactivity Recombinant Human IL-1 beta/IL-1F2 Protein Bioactivity View Larger

Recombinant Human IL-1 beta /IL-1F2 (Catalog # 201-LB) stimulates cell proliferation of the D10.G4.1 mouse helper T cell line. The ED50 for this effect is <12 pg/mL.

SDS-PAGE Recombinant Human IL-1 beta/IL-1F2 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Human IL-1 beta /IL-1F2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-1 beta/IL-1F2

IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL-1 alpha and IL-1 beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1 RI binds directly to IL-1 alpha or IL-1 beta and then associates with IL-1 R accessory protein (IL-1 R3/IL-1 R AcP) to form a high-affinity receptor complex that is competent for signal transduction. IL-1 RII has high affinity for IL-1 beta but functions as a decoy receptor and negative regulator of IL-1 beta activity. IL-1ra functions as a competitive antagonist by preventing IL-1 alpha and IL-1 beta from interacting with IL-1 RI (1-4). The human IL-1 beta cDNA encodes a 269 aa precursor. A 116 aa propeptide is cleaved intracellularly by the cysteine protease IL-1 beta -converting enzyme (Caspase-1/ICE) to generate the active cytokine (5-7). The 17 kDa mature human IL-1 beta shares 96% aa sequence identity with rhesus and 67%-78% with canine, cotton rat, equine, feline, mouse, porcine, and rat IL-1 beta.

References
  1. Allan, S.M. et al. (2005) Nat. Rev. Immunol. 5:629.
  2. Boraschi, D. and A. Tagliabue (2006) Vitam. Horm. 74:229.
  3. Kornman, K.S. (2006) Am. J. Clin. Nutr. 83:475S.
  4. Isoda, K. and F. Ohsuzu (2006) J. Atheroscler. Thromb. 13:21.
  5. March, C.J. et al. (1985) Nature 315:641.
  6. Auron, P.E. et al. (1984) Proc. Natl. Acad. Sci. 81:7907.
  7. Martinon, F. and J. Tschopp (2007) Cell Death Differ. 14:10.
Long Name
Interleukin 1 beta
Entrez Gene IDs
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Product Specific Notices

This product is covered by U.S. patent: 5,681,933.

Citations for Recombinant Human IL-1 beta/IL-1F2 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

549 Citations: Showing 1 - 10
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  1. Geniposidic acid alleviates osteoarthritis progression through inhibiting inflammation and chondrocytes ferroptosis
    Authors: Sun, J;Song, X;Wang, C;Ruan, Q;
    Journal of cellular and molecular medicine
    Species: Murine polyomavirus strain A3
    Sample Types: Whole Cells
    Applications: Bioassay
  2. IRF1 Mediates Growth Arrest and the Induction of a Secretory Phenotype in Alveolar Epithelial Cells in Response to Inflammatory Cytokines IFN?/TNF?
    Authors: Recchia Luciani, G;Barilli, A;Visigalli, R;Sala, R;Dall'Asta, V;Rotoli, BM;
    International journal of molecular sciences
    Species: Human hepegivirus
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade
    Authors: Chen, S;McMiller, TL;Soni, A;Succaria, F;Sidhom, JW;Cappelli, LC;Casciola-Rosen, LA;Morales, IR;Sankaran, P;Berger, AE;Deutsch, JS;Zhu, QC;Anders, RA;Hooper, JE;Pardoll, DM;Lipson, EJ;Taube, JM;Topalian, SL;
    Journal of translational medicine
    Species: Human hepegivirus
    Sample Types: Whole Cells
    Applications: Bioassay
  4. RGS4 controls airway hyperresponsiveness through GAP-independent mechanisms
    Authors: Joshi, IV;Chan, EC;Lack, JB;Liu, C;Druey, KM;
    The Journal of biological chemistry
    Species: Human hepegivirus
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Quercetin-3-O-?-D-glucuronide attenuates osteoarthritis by inhibiting cartilage extracellular matrix degradation and inflammation
    Authors: Mao, H;Feng, Y;Feng, J;Yusufu, Y;Sun, M;Yang, L;Jiang, Q;
    Journal of orthopaedic translation
    Species: Human hepegivirus
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Dysregulation of the mRNA Expression of Human Renal Drug Transporters by Proinflammatory Cytokines in Primary Human Proximal Tubular Epithelial Cells
    Authors: Tsang, YP;Hao, T;Mao, Q;Kelly, EJ;Unadkat, JD;
    Pharmaceutics
    Species: Human hepegivirus
    Sample Types: Whole Cells
    Applications: Bioassay
  7. TAp63, a methotrexate target in CD4+ T cells, suppresses Foxp3 expression and exacerbates autoimmune arthritis
    Authors: Suga, K;Suto, A;Tanaka, S;Sugawara, Y;Kageyama, T;Ishikawa, J;Sanayama, Y;Ikeda, K;Furuta, S;Kagami, SI;Iwata, A;Hirose, K;Suzuki, K;Ohara, O;Nakajima, H;
    JCI insight
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Serelaxin Alleviates Fibrosis in Thyroid-Associated Ophthalmopathy via the Notch Pathway
    Authors: Sun, A;Ye, H;Xu, Z;Chen, J;Xiao, W;Zhang, T;Sha, X;Bi, S;Zhou, T;Yang, H;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction
    Authors: HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo
    PLoS ONE, 2023-04-20;18(4):e0281834.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Capture
  10. Regulatory mechanisms of kaempferol on iNOS expression in RINm5F beta-cells under exposure to interleukin-1beta
    Authors: SY Chang, Y Ko, MJ Kim
    Heliyon, 2023-03-23;9(4):e14818.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  11. BCL-XL Overexpression Protects Pancreatic beta-Cells against Cytokine- and Palmitate-Induced Apoptosis
    Authors: AA Perez-Sern, RS Dos Santos, C Ripoll, A Nadal, DL Eizirik, L Marroqui
    International Journal of Molecular Sciences, 2023-03-16;24(6):.
    Species: Human, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Simultaneous quantitative analysis and in vitro anti-arthritic effects of five polyphenols from Terminalia chebula
    Authors: F Liu, S Zhan, P Zhang, C Jia, Q Zhu, Q Dai, M Yu, L Cheng, L Xiong, F Sun, P Xia, X Zhang, J Hu
    Frontiers in Physiology, 2023-03-08;14(0):1138947.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  13. Role of pulmonary epithelial arginase-II in activation of fibroblasts and lung inflammaging
    Authors: C Zhu, DM Potenza, Y Yang, G Ajalbert, KD Mertz, S von Gunten, XF Ming, Z Yang
    Aging Cell, 2023-02-15;0(0):e13790.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells
    Authors: F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber
    bioRxiv : the preprint server for biology, 2023-02-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Selective Transcription Factor Blockade Reduces Human Retinal Endothelial Cell Expression of Intercellular Adhesion Molecule-1 and Leukocyte Binding
    Authors: Y Ma, LM Ashander, B Appukuttan, FJ Ryan, ACR Tan, JM Matthews, MZ Michael, DJ Lynn, JR Smith
    International Journal of Molecular Sciences, 2023-02-07;24(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Salmonella Typhimurium Infection Reduces the Ascorbic Acid Uptake in the Intestine
    Authors: T Teafatille, SB Subramanya, N Lambrecht, VS Subramania
    Mediators of Inflammation, 2023-01-17;2023(0):2629262.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells
    Authors: S Sim, DH Lee, KS Kim, HJ Park, YK Kim, Y Choi, HS Park
    Experimental & Molecular Medicine, 2023-01-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Silencing miR-146a-5p Protects against Injury-Induced Osteoarthritis in Mice
    Authors: H Qin, C Wang, Y He, A Lu, T Li, B Zhang, J Shen
    Biomolecules, 2023-01-07;13(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  19. CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response
    Authors: L Cao, X Ma, J Zhang, M Yang, Z He, C Yang, S Li, P Rong, W Wang
    Cell Transplantation, 2023-01-01;32(0):9636897221149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes
    Authors: DS Yoon, EJ Kim, S Cho, S Jung, KM Lee, KH Park, JW Lee, SH Kim
    International journal of biological sciences, 2023-01-01;19(1):13-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Regulatory mechanisms of kaempferol on iNOS expression in RINm5F beta-cells under exposure to interleukin-1beta
    Authors: SY Chang, Y Ko, MJ Kim
    Heliyon, 2023;9(4):e14818.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  22. Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction
    Authors: HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo
    PLoS ONE, 2023;18(4):e0281834.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Capture
  23. Gene Expression Linked to Reepithelialization of Human Skin Wounds
    Authors: MS Ågren, T Litman, JO Eriksen, P Schjerling, M Bzorek, LMR Gjerdrum
    International Journal of Molecular Sciences, 2022-12-12;23(24):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial
    Authors: N Gerwin, C Scotti, C Halleux, M Fornaro, J Elliott, Y Zhang, K Johnson, J Shi, S Walter, Y Li, C Jacobi, N Laplanche, M Belaud, J Paul, G Glowacki, T Peters, KA Wharton, I Vostiar, F Polus, I Kramer, S Guth, A Seroutou, S Choudhury, D Laurent, J Gimbel, J Goldhahn, M Schieker, S Brachat, R Roubenoff, M Kneissel
    Nature Medicine, 2022-12-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Dienogest May Reduce Estradiol- and Inflammatory Cytokine-Induced Cell Viability and Proliferation and Inhibit the Pathogenesis of Endometriosis: A Cell Culture- and Mouse Model-Based Study
    Authors: HJ Kim, SH Kim, YS Oh, SR Lee, HD Chae
    Biomedicines, 2022-11-21;10(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  26. ST3GAL3 Promotes the Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Activating the TLR9/MyD88 Pathway
    Authors: L Xu, X Niu, Y Liu, L Liu
    Mediators of Inflammation, 2022-11-10;2022(0):4258742.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic beta Cells
    Authors: S Kaur, C Frørup, AH Mirza, T Fløyel, R Yarani, ML Colli, J Johannesen, J Størling, DL Eizirik, F Pociot
    Non-coding RNA, 2022-10-12;8(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism
    Authors: R Chandrasek, C Mathieu, R Sheth, AP Cheng, D Fong, R McCormack, H El-Gabalaw, S Alishetty, M Paige, CD Hoemann
    PLoS ONE, 2022-09-15;17(9):e0274420.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Knockdown of LMX1B Suppressed Cell Apoptosis and Inflammatory Response in IL-1beta-Induced Human Osteoarthritis Chondrocytes through NF-kappaB and NLRP3 Signal Pathway
    Authors: Y Mu, L Wang, L Fu, Q Li
    Mediators of Inflammation, 2022-09-12;2022(0):1870579.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Inflammation and Oxidative Stress Induce NGF Secretion by Pulmonary Arterial Cells through a TGF-beta1-Dependent Mechanism
    Authors: C Bouchet, G Cardouat, M Douard, F Coste, P Robillard, F Delcambre, T Ducret, JF Quignard, P Vacher, I Baudrimont, R Marthan, P Berger, C Guibert, V Freund-Mic
    Cells, 2022-09-07;11(18):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes
    Authors: F Lemaître, N Farzam-Kia, A Carmena Mo, Y Carpentier, ML Clenet, O Tastet, A Cleret-Buh, JV Guimond, E Haddad, P Duquette, JM Girard, A Prat, C Larochelle, N Arbour
    Journal of Neuroinflammation, 2022-09-01;19(1):212.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-kappaB-Dependent Inflammatory/Catabolic Environment of Osteoarthritis
    Authors: C Cavallo, G Merli, N Zini, S D'Adamo, L Cattini, M Guescini, B Grigolo, A Di Martino, S Santi, RM Borzì, G Filardo
    Stem Cells International, 2022-07-18;2022(0):9376338.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Meniscus surface texture is associated with degenerative changes in biological and biomechanical properties
    Authors: S Otani, T Kanamoto, S Oyama, S Yamakawa, W Shi, R Miyazaki, M Aihara, S Oka, S Kuroda, T Nakai, K Takenaka, Y Sato, M Tsukamoto, A Tsujii, K Ebina, S Okada, K Nakata
    Scientific Reports, 2022-07-13;12(1):11977.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Articular surface integrity assessed by ultrasound is associated with biological characteristics of articular cartilage in early-stage degeneration
    Authors: W Shi, T Kanamoto, M Aihara, S Oka, S Kuroda, T Nakai, T Mazuka, K Takenaka, Y Sato, M Tsukamoto, K Ebina, K Nakata
    Scientific Reports, 2022-07-13;12(1):11970.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-beta1 Expression in the Corneal Epithelium
    Authors: J Xu, P Chen, X Luan, X Yuan, S Wei, Y Li, C Guo, X Wu, G Di
    Investigative Ophthalmology & Visual Science, 2022-07-08;63(8):15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity by targeting Nrf2 and NEK7-NLRP3 signaling pathway
    Authors: Y Yao, R Li, D Liu, L Long, N He
    Ecotoxicology and environmental safety, 2022-06-24;241(0):113773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Identification of a distal enhancer that determines the expression pattern of acute phase marker C-reactive protein
    Authors: MY Wang, CM Zhang, HH Zhou, ZB Ge, CC Su, ZH Lou, XY Zhang, TT Xu, SY Li, L Zhu, YL Zhou, Y Wu, SR Ji
    Oncogene, 2022-06-17;0(0):102160.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Clusterin exacerbates interleukin-1beta-induced inflammation via suppressing PI3K/Akt pathway in human fibroblast-like synoviocytes of knee osteoarthritis
    Authors: T Ungsudecha, S Honsawek, J Jittikoon, W Udomsinpra
    Oncogene, 2022-06-15;12(1):9963.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation
    Authors: A Shetty, SK Tripathi, S Junttila, T Buchacher, R Biradar, SD Bhosale, T Envall, A Laiho, R Moulder, O Rasool, S Galande, LL Elo, R Lahesmaa
    Nucleic Acids Research, 2022-05-20;50(9):4938-4958.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Bead Number Effect in a Magnetic-Beads-Based Digital Microfluidic Immunoassay
    Authors: W Hsu, YT Shih, MS Lee, HY Huang, WN Wu
    Biosensors, 2022-05-16;12(5):.
    Species: Human
    Sample Types: Recombinant Proteins
    Applications: ELISA Capture
  41. Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions
    Authors: R Boi, K Ebefors, M Henricsson, J Borén, J Nyström
    Scientific Reports, 2022-05-05;12(1):7322.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  42. Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
    Authors: Y Huang, E Motta, C Nanvuma, LD Kuhrt, Y Yuan, P Xia, M Lubas, S Zhu, M Schnauss, N Qazi, F Hu, H Zhang, T Lei, M Synowitz, C Flüh, H Kettenmann
    Cell Reports, 2022-04-12;39(2):110670.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation
    Authors: R Giri, EC Hoedt, S Khushi, AA Salim, AS Bergot, V Schreiber, R Thomas, MA McGuckin, TH Florin, M Morrison, RJ Capon, P Ó Cuív, J Begun
    Cell Reports, 2022-04-12;39(2):110646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Citrullination of glucokinase is linked to autoimmune diabetes
    Authors: ML Yang, S Horstman, R Gee, P Guyer, TT Lam, J Kanyo, AL Perdigoto, C Speake, CJ Greenbaum, A Callebaut, L Overbergh, RG Kibbey, KC Herold, EA James, MJ Mamula
    Nature Communications, 2022-04-06;13(1):1870.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1
    Authors: T Lehtola, E Nummenmaa, L Tuure, M Hämäläinen, RM Nieminen, T Moilanen, A Pemmari, E Moilanen
    International Journal of Molecular Sciences, 2022-03-31;23(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-kappaB pathways
    Authors: M Yu, X Wu, J Wang, M He, H Han, S Hu, J Xu, M Yang, Q Tan, Y Wang, H Wang, W Xie, H Kong
    International Journal of Medical Sciences, 2022-03-28;19(4):681-694.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. RORgammat phosphorylation protects against T�cell-mediated inflammation
    Authors: S Ma, SA Patel, Y Abe, N Chen, PR Patel, BS Cho, N Abbasi, S Zeng, B Schnabl, JT Chang, WJM Huang
    Cell Reports, 2022-03-15;38(11):110520.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  48. The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells
    Authors: P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes
    Cancers, 2022-03-11;14(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  49. Human C1q Regulates Influenza A Virus Infection and Inflammatory Response via Its Globular Domain
    Authors: PM Varghese, U Kishore, R Rajkumari
    International Journal of Molecular Sciences, 2022-03-11;23(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Pro-Inflammatory Cytokines Trigger the Overexpression of Tumour-Related Splice Variant RAC1B in Polarized Colorectal Cells
    Authors: JFS Pereira, C Bessa, P Matos, P Jordan
    Cancers, 2022-03-09;14(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  51. Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling
    Authors: C Ge, J Tan, D Lou, L Zhu, Z Zhong, X Dai, Y Sun, Q Kuang, J Zhao, L Wang, J Liu, B Wang, M Xu
    Redox Biology, 2022-02-24;51(0):102274.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. IL?1beta?induced pentraxin 3 inhibits the proliferation, invasion and cell cycle of trophoblasts in preeclampsia and is suppressed by IL?1beta antagonists
    Authors: X Wang, J Zhang, J Ji
    Molecular Medicine Reports, 2022-02-09;25(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. The IGFBP3/TMEM219 pathway regulates beta cell homeostasis
    Authors: F D'Addio, A Maestroni, E Assi, M Ben Nasr, G Amabile, V Usuelli, C Loretelli, F Bertuzzi, B Antonioli, F Cardarelli, B El Essawy, A Solini, IC Gerling, C Bianchi, G Becchi, S Mazzucchel, D Corradi, GP Fadini, D Foschi, JF Markmann, E Orsi, J Škrha, MG Camboni, R Abdi, AM James Shap, F Folli, J Ludvigsson, S Del Prato, G Zuccotti, P Fiorina
    Nature Communications, 2022-02-03;13(1):684.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization
    Authors: N Rana, S Suliman, N Al-Sharabi, K Mustafa
    Cells, 2022-01-29;11(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. miR-29b inhibits TGF-beta1-induced cell proliferation in articular chondrocytes
    Authors: M Horita, SN Hsu, A Raper, C Farquharso, LA Stephen
    Biochemistry and Biophysics Reports, 2022-01-24;29(0):101216.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial
    Authors: N Gerwin, C Scotti, C Halleux, M Fornaro, J Elliott, Y Zhang, K Johnson, J Shi, S Walter, Y Li, C Jacobi, N Laplanche, M Belaud, J Paul, G Glowacki, T Peters, KA Wharton, I Vostiar, F Polus, I Kramer, S Guth, A Seroutou, S Choudhury, D Laurent, J Gimbel, J Goldhahn, M Schieker, S Brachat, R Roubenoff, M Kneissel
    Nature Medicine, 2022;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Dynamic changes in beta-cell [Ca2+] regulates NFAT activation, gene transcription and islet gap junction communication
    Authors: JG Miranda, WE Schleicher, KL Wells, DG Ramirez, SP Landgrave, RK Benninger
    Oncogene, 2021-12-31;0(0):101430.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma
    Authors: A Tosi, L Nardinocch, ML Carbone, L Capriotti, E Pagani, S Mastroeni, C Fortes, F Scopelliti, C Cattani, F Passarelli, A Rosato, S D'Atri, CM Failla, A Cavani
    Biomedicines, 2021-12-16;9(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
    Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
    Cell Reports, 2021-11-23;37(8):110037.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  60. Takinib Inhibits Inflammation in Human Rheumatoid Arthritis Synovial Fibroblasts by Targeting the Janus Kinase-Signal Transducer and Activator of Transcription 3 (JAK/STAT3) Pathway
    Authors: PM Panipinto, AK Singh, FS Shaikh, RJ Siegel, M Chourasia, S Ahmed
    International Journal of Molecular Sciences, 2021-11-22;22(22):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Small molecule allosteric inhibitors of RORgammat block Th17-dependent inflammation and associated gene expression in vivo
    Authors: SA Saenz, A Local, T Carr, A Shakya, S Koul, H Hu, L Chourb, J Stedman, J Malley, LA D'Agostino, V Shanmugasu, J Malona, CE Schwartz, L Beebe, M Clements, G Rajaraman, J Cho, L Jiang, A Dubrovskiy, M Kreilein, R Shimanovic, LG Hamann, L Escoubet, JM Ellis
    PLoS ONE, 2021-11-09;16(11):e0248034.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
    Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
    The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. HSPA13 facilitates NF-kappaB-mediated transcription and attenuates cell death responses in TNFalpha signaling
    Authors: C Gao, J Deng, H Zhang, X Li, S Gu, M Zheng, M Tang, Y Zhu, X Lin, J Jin, L Zhang, J Huang, J Zou, ZP Xia, PL Xu, L Shen, B Zhao, XH Feng
    Science Advances, 2021-10-06;7(41):eabh1756.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
    Authors: P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonn, L Liu, E Ruppin, L Wakefield, KW Wucherpfen
    Nature methods, 2021-09-30;18(10):1181-1191.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Endolysosomal ion channel MCOLN2 (Mucolipin-2) promotes prostate cancer progression via IL-1beta/NF-kappaB pathway
    Authors: H Yu, M Xie, Z Meng, CY Lo, FL Chan, L Jiang, X Meng, X Yao
    British Journal of Cancer, 2021-09-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis
    Authors: HK Min, S Kim, JY Lee, KW Kim, SH Lee, HR Kim
    Journal of Translational Medicine, 2021-09-16;19(1):392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation
    Authors: JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng
    Frontiers in Cellular Neuroscience, 2021-09-07;15(0):683687.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Pro-inflammatory beta cell small extracellular vesicles induce beta cell failure through activation of the CXCL10/CXCR3 axis in diabetes
    Authors: N Javeed, TK Her, MR Brown, P Vanderboom, K Rakshit, AM Egan, A Vella, I Lanza, AV Matveyenko
    Cell Reports, 2021-08-24;36(8):109613.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  69. Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96?Transwell air-liquid interface model
    Authors: T Bluhmki, S Traub, AK Müller, S Bitzer, E Schruf, MT Bammert, M Leist, F Gantner, JP Garnett, R Heilker
    Scientific Reports, 2021-08-23;11(1):17028.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function
    Authors: H Gassmann, K Schneider, V Evdokimova, P Ruzanov, SJ Schober, B Xue, K von Heykin, M Thiede, GHS Richter, MW Pfaffl, E Noessner, LD Stein, PH Sorensen, SEG Burdach, U Thiel
    Cells, 2021-08-13;10(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-beta1
    Authors: EL Woods, IV Grigorieva, AC Midgley, CVM Brown, YA Lu, AO Phillips, T Bowen, S Meran, R Steadman
    The Journal of Biological Chemistry, 2021-08-06;0(0):100987.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Inhibition of PHLPP1/2 phosphatases rescues pancreatic beta-cells in diabetes
    Authors: B Lupse, K Annamalai, H Ibrahim, S Kaur, S Geravandi, B Sarma, A Pal, S Awal, A Joshi, S Rafizadeh, MK Madduri, M Khazaei, H Liu, T Yuan, W He, KDD Gorrepati, Z Azizi, Q Qi, K Ye, J Oberholzer, K Maedler, A Ardestani
    Cell Reports, 2021-08-03;36(5):109490.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis
    Authors: R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, D Cesana, P Gallina, M Norelli, L Basso-Ricc, A Bondanza, G Cavalli, M Ponzoni, L Dagna, C Doglioni, A Aiuti, I Merelli, R Di Micco, E Montini
    Nature Communications, 2021-07-27;12(1):4559.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells
    Authors: S Luostarine, M Hämäläinen, N Hatano, K Muraki, E Moilanen
    Pulmonary pharmacology & therapeutics, 2021-07-21;70(0):102059.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis
    Authors: JK Park, S Shon, HJ Yoo, DH Suh, D Bae, J Shin, JH Jun, N Ha, H Song, YI Choi, T Pap, YW Song
    Arthritis Research & Therapy, 2021-07-05;23(1):177.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Protective effects of the knockdown of lncRNA AK139328 against oxygen glucose deprivation/reoxygenation-induced injury in PC12 cells
    Authors: L Liu, B Zheng, Z Wang
    Molecular Medicine Reports, 2021-07-02;24(3):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  77. Post-myocardial infarction heart failure dysregulates the bone vascular niche
    Authors: J Hoffmann, G Luxán, WT Abplanalp, SF Glaser, T Rasper, A Fischer, M Muhly-Rein, M Potente, B Assmus, D John, AM Zeiher, S Dimmeler
    Nature Communications, 2021-06-25;12(1):3964.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1beta-induced inflammation
    Authors: Y Takashima, S Hayashi, K Fukuda, T Maeda, M Tsubosaka, T Kamenaga, K Kikuchi, M Fujita, Y Kuroda, S Hashimoto, N Nakano, T Matsumoto, R Kuroda
    Scientific Reports, 2021-06-15;11(1):12516.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Food Contaminants Effects on an In Vitro Model of Human Intestinal Epithelium
    Authors: M Guibourden, J Haug, N Chevalier, M Spatz, N Barbezier, J Gay-Quéhei, PM Anton
    Toxics, 2021-06-09;9(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  80. In vitro responses to platelet-rich-plasma are associated with variable clinical outcomes in patients with knee osteoarthritis
    Authors: H Zahir, B Dehghani, X Yuan, Y Chinenov, C Kim, A Burge, R Bandhari, D Nemirov, P Fava, P Moley, H Potter, J Nguyen, B Halpern, L Donlin, L Ivashkiv, S Rodeo, M Otero
    Scientific Reports, 2021-06-01;11(1):11493.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. The discriminatory power of the T cell receptor
    Authors: J Pettmann, A Huhn, E Abu Shah, MA Kutuzov, DB Wilson, ML Dustin, SJ Davis, PA van der Me, O Dushek
    Elife, 2021-05-25;10(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation
    Authors: P Cheung, S Schaffert, SE Chang, M Dvorak, M Donato, C Macaubas, MH Foecke, TM Li, L Zhang, JP Coan, GS Schulert, AA Grom, LA Henderson, PA Nigrovic, JE Elias, O Gozani, ED Mellins, P Khatri, PJ Utz, AJ Kuo
    Nature Immunology, 2021-05-20;22(6):711-722.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Multi-Omics Analysis of Anti-Inflammatory Action of Alkaline Extract of the Leaves of Sasa sp
    Authors: H Sakagami, S Nakatani, A Enomoto, S Ota, M Kaneko, M Sugimoto, M Horiuchi, K Toeda, T Oizumi
    Journal of Clinical Medicine, 2021-05-13;10(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Empagliflozin Inhibits IL-1&beta-Mediated Inflammatory Response in Human Proximal Tubular Cells
    Authors: M Pirklbauer, S Sallaberge, P Staudinger, U Corazza, J Leierer, G Mayer, H Schramek
    International Journal of Molecular Sciences, 2021-05-11;22(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Oral Administration of Lactobacillus rhamnosus Ameliorates the Progression of Osteoarthritis by Inhibiting Joint Pain and Inflammation
    Authors: J Jhun, KH Cho, DH Lee, JY Kwon, JS Woo, J Kim, HS Na, SH Park, SJ Kim, ML Cho
    Cells, 2021-04-29;10(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Anti-inflammatory Effects of Alcohol Are Associated with JNK-STAT3 Downregulation in an In Vitro Inflammation Model in HepG2 Cells
    Authors: K Mörs, R Sturm, JA Hörauf, S Kany, P Cavalli, J Omari, M Powerski, A Surov, I Marzi, AJ Nowak, B Relja
    Disease Markers, 2021-03-18;2021(0):6622701.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Effect of NIR Laser Therapy by MLS-MiS Source on Fibroblast Activation by Inflammatory Cytokines in Relation to Wound Healing
    Authors: S Genah, F Cialdai, V Ciccone, E Sereni, L Morbidelli, M Monici
    Biomedicines, 2021-03-16;9(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
    Authors: P Rueda, J Merlin, S Chimenti, M Feletou, J Paysant, PJ White, A Christopou, PM Sexton, RJ Summers, WN Charman, LT May, CJ Langmead
    Frontiers in Pharmacology, 2021-03-11;12(0):628060.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  89. N4BP1 negatively regulates NF-&kappaB by binding and inhibiting NEMO oligomerization
    Authors: H Shi, L Sun, Y Wang, A Liu, X Zhan, X Li, M Tang, P Anderton, S Hildebrand, J Quan, S Ludwig, EMY Moresco, B Beutler
    Nature Communications, 2021-03-02;12(1):1379.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Interleukin-1&alpha Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation
    Authors: K Bernau, JP Leet, H Floerke, EM Bruhn, AL Noll, IS McDermott, S Esnault, NN Jarjour, N Sandbo
    Cells, 2021-03-02;10(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm
    Authors: P Gao, P Gao, J Zhao, S Shan, W Luo, OJ Slivano, W Zhang, A Tabuchi, SA LeMaire, L Maegdefess, YH Shen, JM Miano, HA Singer, X Long
    Redox Biology, 2021-02-20;41(0):101903.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
    Authors: P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski
    Arthritis Research & Therapy, 2021-02-15;23(1):56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. MicroRNA?186?5p downregulation inhibits osteoarthritis development by targeting MAPK1
    Authors: Q Li, M Wu, G Fang, K Li, W Cui, L Li, X Li, J Wang, Y Cang
    Molecular Medicine Reports, 2021-02-04;23(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Small Extracellular Vesicles from adipose derived stromal cells significantly attenuate in vitro the NF-&kappaB dependent inflammatory/catabolic environment of osteoarthritis
    Authors: C Cavallo, G Merli, RM Borzì, N Zini, S D'Adamo, M Guescini, B Grigolo, A Di Martino, S Santi, G Filardo
    Scientific Reports, 2021-01-13;11(1):1053.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes
    Authors: TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV
    EBioMedicine, 2021-01-12;63(0):103175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Novel role of circRSU1 in the progression of osteoarthritis by adjusting oxidative stress
    Authors: Y Yang, P Shen, T Yao, J Ma, Z Chen, J Zhu, Z Gong, S Shen, X Fang
    Theranostics, 2021-01-01;11(4):1877-1900.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Benefit of Belatacept in Cord Blood-Derived Regulatory T Cell-Mediated Suppression of Alloimmune Response
    Authors: X He, S Li, J Zhang, L Cao, C Yang, P Rong, S Yi, K Ghimire, X Ma, W Wang
    Cell Transplantation, 2021-01-01;30(0):9636897211046.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Transient Receptor Potential Ankyrin 1 (TRPA1) Is Involved in Upregulating Interleukin-6 Expression in Osteoarthritic Chondrocyte Models
    Authors: E Nummenmaa, M Hämäläinen, A Pemmari, LJ Moilanen, L Tuure, RM Nieminen, T Moilanen, K Vuolteenah, E Moilanen
    International Journal of Molecular Sciences, 2020-12-23;22(1):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  99. CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci
    Authors: J Martinez-F, L Wang, E Pohler, A Cozzani, S Wilmes, M Kazemian, S Mitra, I Moraga
    Cell Reports, 2020-12-22;33(12):108545.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer Progression
    Authors: YC Fan, KD Lee, YC Tsai
    Biomedicines, 2020-12-13;8(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  101. Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease
    Authors: N Gatto, C Dos Santos, AC Shaw, SM Bell, MA Myszczynsk, S Powers, K Meyer, LM Castelli, E Karyka, H Mortiboys, M Azzouz, GM Hautbergue, NM Márkus, PJ Shaw, L Ferraiuolo
    Aging Cell, 2020-12-13;0(0):e13281.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors.
    Authors: Roudko V, Bozkus C, Orfanelli T, McClain C, Carr C, O'Donnell T, Chakraborty L, Samstein R, Huang K, Blank S, Greenbaum B, Bhardwaj N
    Cell, 2020-11-30;183(6):1634-1649.e17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. In vitro model of distinct catabolic and inflammatory response patterns of endothelial cells to intervertebral disc cell degeneration
    Authors: MH Hwang, HG Son, J Kim, H Choi
    Sci Rep, 2020-11-26;10(1):20596.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  104. Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells
    Authors: MM Mostafa, A Bansal, AN Michi, SK Sasse, D Proud, AN Gerber, R Newton
    J Biol Chem, 2020-11-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  105. In vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts
    Authors: D Hortobagyi, T Grossmann, M Tschernitz, M Grill, A Kirsch, C Gerstenber, M Gugatschka
    PLoS ONE, 2020-11-19;15(11):e0241901.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  106. Endogenous antisense RNA curbs CD39 expression in Crohn's disease
    Authors: RP Harshe, A Xie, M Vuerich, LA Frank, B Gromova, H Zhang, RJ Robles, S Mukherjee, E Csizmadia, E Kokkotou, AS Cheifetz, AC Moss, SK Kota, SC Robson, MS Longhi
    Nat Commun, 2020-11-18;11(1):5894.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. In Vitro Anti-Inflammatory Activity in Arthritic Synoviocytes of A. brachypoda Root Extracts and Its Unusual Dimeric Flavonoids
    Authors: C Salgado, H Morin, N Coriolano, L Neff, C Quintino d, W Vilegas, L Marcourt, JL Wolfender, O Jordan, E Ferreira Q, E Allémann
    Molecules, 2020-11-09;25(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  108. &beta-Catenin Regulates Wound Healing and IL-6 Expression in Activated Human Astrocytes
    Authors: VV Edara, S Nooka, J Proulx, S Stacy, A Ghorpade, K Borgmann
    Biomedicines, 2020-11-06;8(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  109. Inflammation-associated senescence promotes Helicobacter pylori-induced atrophic gastritis
    Authors: Q Cai, P Shi, Y Yuan, J Peng, X Ou, W Zhou, J Li, T Su, L Lin, S Cai, Y He, J Xu
    Cell Mol Gastroenterol Hepatol, 2020-11-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations
    Authors: D He, D Wang, P Lu, N Yang, Z Xue, X Zhu, P Zhang, G Fan
    Oncogene, 2020-11-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  111. Boosting NAD Level Suppresses Inflammatory Activation of PBMC in Heart Failure
    Authors: B Zhou, DD Wang, Y Qiu, S Airhart, Y Liu, A Stempien-O, KD O'Brien, R Tian
    J. Clin. Invest., 2020-11-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Luteolin Attenuates IL-1&beta-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-&kappaB and MAPK Pathways
    Authors: WC Huang, CJ Liou, SC Shen, S Hu, CY Hsiao, SJ Wu
    Mediators Inflamm, 2020-10-16;2020(0):9421340.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Binding Mode Exploration of B1 Receptor Antagonists' by the Use of Molecular Dynamics and Docking Simulation-How Different Target Engagement Can Determine Different Biological Effects
    Authors: M Gemei, C Talarico, L Brandolini, C Manelfi, L Za, S Bovolenta, C Liberati, LD Vecchio, R Russo, C Cerchia, M Allegretti, AR Beccari
    Int J Mol Sci, 2020-10-16;21(20):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  114. Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation
    Authors: EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay
    PLoS ONE, 2020-10-06;15(10):e0240319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  115. An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression
    Authors: CM Schafer, JM Gurley, K Kurylowicz, PK Lin, W Chen, MH Elliott, GE Davis, F Bhatti, CT Griffin
    Proc Natl Acad Sci U S A, 2020-10-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Oleanolic Acid Decreases IL-1&beta-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-&kappaB Axis in Osteoarthritis
    Authors: J Bao, W Yan, K Xu, M Chen, Z Chen, J Ran, Y Xiong, L Wu
    Oxid Med Cell Longev, 2020-09-28;2020(0):7517219.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/I&kappaB&alpha pathway
    Authors: HK Min, JY Won, BM Kim, KA Lee, SJ Lee, SH Lee, HR Kim, KW Kim
    Arthritis Research & Therapy, 2020-09-23;22(1):222.
    Species: Human
    Sample Types: Reference Standard
  118. The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta
    Authors: J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, AJ O'Donoghue, V Nizet, CN LaRock
    EBioMedicine, 2020-09-23;60(0):102984.
    Species: Mouse
    Sample Types: Reference Standard, Whole Cells
    Applications: Inhibition
  119. Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes
    Authors: C Wang, Y Xiao, M Lao, J Wang, S Xu, R Li, X Xu, Y Kuang, M Shi, Y Zou, Q Wang, L Liang, SG Zheng, H Xu
    JCI Insight, 2020-09-17;5(18):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. The innate immunity protein IFITM3 modulates &gamma-secretase in Alzheimer's disease
    Authors: JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, Y Zhai, JC Wang, J Tcw, L Guo, A McKenzie, C Ming, X Zhou, M Wang, Y Sagi, AE Renton, BT Esposito, Y Kim, KR Sadleir, I Trinh, RA Rissman, R Vassar, B Zhang, DS Johnson, E Masliah, P Greengard, A Goate, YM Li
    Nature, 2020-09-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells
    Authors: M Fellermann, C Huchler, L Fechter, T Kolb, F Wondany, D Mayer, J Michaelis, S Stenger, K Mellert, P Möller, TFE Barth, S Fischer, H Barth
    Toxins (Basel), 2020-09-01;12(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia
    Authors: S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim
    Cells, 2020-08-31;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Peucedanum ostruthium Inhibits E-Selectin and VCAM-1 Expression in Endothelial Cells through Interference with NF-&kappaB Signaling
    Authors: C Lammel, J Zwirchmayr, J Seigner, JM Rollinger, R de Martin
    Biomolecules, 2020-08-21;10(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Nano wet milled celecoxib extended release microparticles for local management of chronic inflammation
    Authors: C Salgado, L Guénée, R ?erný, E Allémann, O Jordan
    Int J Pharm, 2020-08-19;589(0):119783.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses
    Authors: E Abu-Shah, N Trendel, P Kruger, J Nguyen, J Pettmann, M Kutuzov, O Dushek
    J. Immunol., 2020-08-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Protein tyrosine phosphatase 1B as a therapeutic target for Graves' orbitopathy in an in vitro model
    Authors: HJ Byeon, JY Kim, J Ko, EJ Lee, K Don, JS Yoon
    PLoS ONE, 2020-08-06;15(8):e0237015.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  127. Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles
    Authors: JF Marchini, A Manica, P Crestani, J Dutzmann, EJ Folco, H Weber, P Libby, K Croce
    J Am Heart Assoc, 2020-07-31;9(15):e015878.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1&beta-CX3CL1-TGF&beta1 signal axis
    Authors: YT Hsu, CH Wu, CY Chao, YS Wei, YC Chang, YT Chen, SL Lin, SY Tsai, YJ Lee, PS Tsai
    Sci Rep, 2020-07-13;10(1):11496.
    Species: Porcine
    Sample Types: Serum
  129. Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells
    Authors: H El-Kehdy, M Najar, J De Kock, DM Agha, V Rogiers, M Merimi, L Lagneaux, EM Sokal, M Najimi
    Cells, 2020-07-08;9(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  130. LC-ESI-FT-MSn Metabolite Profiling of Symphytum officinale L. Roots Leads to Isolation of Comfreyn A, an Unusual Arylnaphthalene Lignan
    Authors: G D'Urso, M Masullo, J Seigner, YM Holper-Sch, R de Martin, A Plaza, S Piacente
    Int J Mol Sci, 2020-06-30;21(13):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  131. The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation
    Authors: Q Wang, K Notay, GP Downey, CA McCulloch
    Cell Rep, 2020-06-30;31(13):107781.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Agonism of GPR120 prevented IL-1&beta-induced reduction of extracellular matrix through SOX-9
    Authors: Z Xu, T Ke, Y Zhang, C Fu, W He
    Aging (Albany NY), 2020-06-24;12(12):12074-12085.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  133. Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms
    Authors: MP Wandel, BH Kim, ES Park, KB Boyle, K Nayak, B Lagrange, A Herod, T Henry, M Zilbauer, J Rohde, JD MacMicking, F Randow
    Nat. Immunol., 2020-06-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone
    Authors: F Nishimura, H Mogami, K Moriuchi, Y Chigusa, M Mandai, E Kondoh
    PLoS ONE, 2020-05-04;15(5):e0231944.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs
    Authors: A Rao, O Strauss, E Kokkinou, M Bruchard, KP Tripathi, H Schlums, A Carrasco, L Mazzurana, V Konya, EJ Villablanc, NK Björkström, U Lindforss, H Spits, J Mjösberg
    Nat Commun, 2020-04-27;11(1):2049.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells
    Authors: W Cho, J Choe
    BMC Immunol., 2020-04-17;21(1):20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  137. Effect of Chemically Induced Hypoxia on Osteogenic and Angiogenic Differentiation of Bone Marrow Mesenchymal Stem Cells and Human Umbilical Vein Endothelial Cells in Direct Coculture
    Authors: VT Nguyen, B Canciani, F Cirillo, L Anastasia, GM Peretti, L Mangiavini
    Cells, 2020-03-19;9(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  138. Therapeutic Effect of Guggulsterone in Primary Cultured Orbital Fibroblasts Obtained From Patients with Graves' Orbitopathy
    Authors: BR Kim, J Kim, JE Lee, EJ Lee, JS Yoon
    Invest. Ophthalmol. Vis. Sci., 2020-03-09;61(3):39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  139. Anti?inflammatory and anti?catabolic effect of non?animal stabilized hyaluronic acid and mesenchymal stem cell?conditioned medium in an osteoarthritis coculture model
    Authors: M Simental-M, SA Lozano-Sep, V Pérez-Silo, L Fuentes-Me, HG Martínez-R, CA Acosta-Oli, VM Peña-Martí, F Vilchez-Ca
    Mol Med Rep, 2020-02-26;21(5):2243-2250.
    Species: Human
    Sample Types: Tissue Explant
    Applications: Bioassay
  140. Galectin 3 Deficiency Alters Chondrocyte Primary Cilium Formation and Exacerbates Cartilage Destruction via Mitochondrial Apoptosis
    Authors: N Hafsia, M Forien, F Renaudin, D Delacour, P Reboul, P Van Lent, M Cohen-Sola, F Lioté, F Poirier, HK Ea
    Int J Mol Sci, 2020-02-22;21(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  141. Anti-fibrotic effect of decorin in peritoneal dialysis and PD-associated peritonitis
    Authors: N Jiang, Q Zhang, MK Chau, MS Yip, SL Lui, S Liu, KM Chu, HY Ngan, TM Chan, S Yung
    EBioMedicine, 2020-02-12;52(0):102661.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Pulsed electromagnetic fields potentiate the paracrine function of mesenchymal stem cells for cartilage regeneration
    Authors: D Parate, ND Kadir, C Celik, EH Lee, JHP Hui, A Franco-Obr, Z Yang
    Stem Cell Res Ther, 2020-02-03;11(1):46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  143. Breast Cancer Cell-Derived Soluble CD44 Promotes Tumor Progression by Triggering Macrophage IL1&beta Production
    Authors: JH Jang, DH Kim, JM Lim, JW Lee, SJ Jeong, KP Kim, YJ Surh
    Cancer Res, 2020-01-22;80(6):1342-1356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Interleukin 1&beta/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy
    Authors: Y Chen, Z Yang, B Deng, D Wu, Y Quan, Z Min
    Oncol. Rep., 2020-01-22;43(3):908-918.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  145. Anti-oxidative and anti-adipogenic effects of caffeine in an in vitro model of Graves' orbitopathy
    Authors: J Ko, JY Kim, JW Kim, JS Yoon
    Endocr. J., 2020-01-16;0(0):.
    Species: Human
    Sample Types:
    Applications: Cell Culture
  146. Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
    Authors: S Demine, AA Schiavo, S Marín-Caña, P Marchetti, M Cnop, DL Eizirik
    Stem Cell Res Ther, 2020-01-03;11(1):7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. IL-35 is critical in suppressing superantigenic Staphylococcus aureus-driven inflammatory Th17 responses in human nasopharynx-associated lymphoid tissue
    Authors: R Xu, RK Shears, R Sharma, M Krishna, C Webb, R Ali, X Wei, A Kadioglu, Q Zhang
    Mucosal Immunol, 2020-01-02;13(3):460-470.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  148. Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells
    Authors: MM Mostafa, A Bansal, AN Michi, SK Sasse, D Proud, AN Gerber, R Newton
    The Journal of Biological Chemistry, 2020-01-01;296(0):100065.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo
    Authors: X Gao, S Jiang, Z Du, A Ke, Q Liang, X Li
    Oxid Med Cell Longev, 2019-11-19;2019(0):8564681.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. MicroRNA-29a Mitigates Subacromial Bursa Fibrosis in Rotator Cuff Lesion with Shoulder Stiffness
    Authors: JY Ko, WS Lian, TC Tsai, YS Chen, CK Hsieh, CW Kuo, FS Wang
    Int J Mol Sci, 2019-11-15;20(22):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  151. Neratinib protects pancreatic beta cells in diabetes
    Authors: A Ardestani, S Li, K Annamalai, B Lupse, S Geravandi, A Dobrowolsk, S Yu, S Zhu, TD Baguley, M Surakattul, J Oetjen, L Hauberg-Lo, R Herranz, S Awal, D Altenhofen, V Nguyen-Tra, S Joseph, PG Schultz, AK Chatterjee, N Rogers, MS Tremblay, W Shen, K Maedler
    Nat Commun, 2019-11-01;10(1):5015.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Microenvironmental IL1beta promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
    Authors: R Eyre, DG Alférez, A Santiago-G, K Spence, JC McConnell, C Hart, BM Simões, D Lefley, C Tulotta, J Storer, A Gurney, N Clarke, M Brown, SJ Howell, AH Sims, G Farnie, PD Ottewell, RB Clarke
    Nat Commun, 2019-11-01;10(1):5016.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  153. Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism
    Authors: K Terabe, Y Ohashi, S Tsuchiya, S Ishizuka, CB Knudson, W Knudson
    J. Biol. Chem., 2019-10-16;0(0):.
    Species: Bovine, Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
    Authors: C Merriman, D Fu
    J. Biol. Chem., 2019-10-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Therapeutic Effect of Curcumin, a Plant Polyphenol Extracted From Curcuma longae, in Fibroblasts From Patients With Graves' Orbitopathy
    Authors: JS Lee, J Kim, EJ Lee, JS Yoon
    Invest. Ophthalmol. Vis. Sci., 2019-10-01;60(13):4129-4140.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Ex vivo physiological compression of human osteoarthritis cartilage modulates cellular and matrix components
    Authors: P Dolzani, E Assirelli, L Pulsatelli, R Meliconi, E Mariani, S Neri
    PLoS ONE, 2019-09-24;14(9):e0222947.
    Species: Human
    Sample Types: Tissue Explant
    Applications: Bioassay
  157. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression
    Authors: J Ren, M Smid, J Iaria, DCF Salvatori, H van Dam, HJ Zhu, JWM Martens, P Ten Dijke
    Breast Cancer Res., 2019-09-18;21(1):109.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
    Authors: JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten
    Cell Rep, 2019-09-03;28(10):2659-2672.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Cancer-associated fibroblast stimulates cancer cell invasion in an interleukin-1 receptor (IL-1R)-dependent manner
    Authors: X Zhang, YS Hwang
    Oncol Lett, 2019-08-27;18(5):4645-4650.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  160. Glucocorticoid receptor inhibits M�ller glial galectin-1 expression via DUSP1-dependent and -independent deactivation of AP-1 signalling
    Authors: I Hirose, A Kanda, K Noda, S Ishida
    J. Cell. Mol. Med., 2019-07-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  161. c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies
    Authors: JH Bernink, Y Ohne, MBM Teunissen, J Wang, J Wu, L Krabbendam, C Guntermann, R Volckmann, J Koster, S van Tol, I Ramirez, Y Shrestha, MA de Rie, H Spits, X Romero Ros, AA Humbles
    Nat. Immunol., 2019-07-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  162. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation
    Authors: L Messerschm, S Fischer, P Wiedemann, A Bringmann, M Hollborn
    Mol. Vis., 2019-06-30;25(0):329-344.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Juvenile idiopathic arthritis associated with a mutation in GATA3
    Authors: AE Patrick, W Wang, E Brokamp, TB Graham, TM Aune, JB Duis
    Arthritis Res. Ther., 2019-06-25;21(1):156.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Metformin Augments Anti-Inflammatory and Chondroprotective Properties of Mesenchymal Stem Cells in Experimental Osteoarthritis
    Authors: MJ Park, SJ Moon, JA Baek, EJ Lee, KA Jung, EK Kim, DS Kim, JH Lee, SK Kwok, JK Min, SJ Kim, SH Park, ML Cho
    J. Immunol., 2019-05-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52
    Authors: K Hacker, S Benke, B Agerer, S Scinicarie, V Budroni, GA Versteeg
    Sci Rep, 2019-05-27;9(1):7901.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Characterization of the non-glandular gastric region microbiota in Helicobacter suis-infected versus non-infected pigs identifies a potential role for Fusobacterium gastrosuis in gastric ulceration
    Authors: C De Witte, K Demeyere, S De Bruycke, B Taminiau, G Daube, R Ducatelle, E Meyer, F Haesebrouc
    Vet. Res., 2019-05-24;50(1):39.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Western Blot Control
  167. Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
    Authors: T Sano, K Akeda, J Yamada, N Takegami, T Sudo, A Sudo
    BMC Musculoskelet Disord, 2019-05-17;20(1):225.
    Species: Human
    Sample Types: Primary Cells
    Applications: Cell Culture
  168. Effect of diclofenac etalhyaluronate (SI-613) on the production of high molecular weight sodium hyaluronate in human synoviocytes
    Authors: T Kisukeda, J Onaya, K Yoshioka
    BMC Musculoskelet Disord, 2019-05-10;20(1):201.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  169. A Symphytum officinale Root Extract Exerts Anti-inflammatory Properties by Affecting Two Distinct Steps of NF-?B Signaling
    Authors: J Seigner, M Junker-Sam, A Plaza, G D'Urso, M Masullo, S Piacente, YM Holper-Sch, R de Martin
    Front Pharmacol, 2019-04-26;10(0):289.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells
    Authors: S Vig, M Buitinga, D Rondas, I Crèvecoeur, M van Zandvo, E Waelkens, DL Eizirik, C Gysemans, P Baatsen, C Mathieu, L Overbergh
    Cell Death Dis, 2019-04-05;10(4):309.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells
    Authors: T Hochdörfer, C Winkler, K Pardali, J Mjösberg
    Eur. J. Immunol., 2019-03-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Determination of two fluoroquinolones and their combinations with hyaluronan effect in in vitro canine cartilage explants
    Authors: P Siengdee, W Pradit, S Chomdej, K Nganvongpa
    PeerJ, 2019-03-12;7(0):e6553.
    Species: Canine
    Sample Types: Tissue Explants
    Applications: Bioassay
  173. A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
    Authors: A Castellano, I Santin, A Olazagoiti, I Romero-Gar, A Jauregi-Mi, M Legarda, JR Bilbao
    Sci Rep, 2019-03-12;9(1):4220.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppression
    Authors: KC Doh, BM Kim, KW Kim, BH Chung, CW Yang
    BMC Complement Altern Med, 2019-03-04;19(1):54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. The role of IL-36? and its regulation in eosinophilic inflammation in allergic rhinitis
    Authors: X Qin, M Liu, S Zhang, C Wang, T Zhang
    Cytokine, 2019-03-01;117(0):84-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis
    Authors: A Kizilyer, MV Singh, VB Singh, S Suwunnakor, J Palis, SB Maggirwar
    Sci Rep, 2019-02-26;9(1):2781.
    Species: Human
    Sample Types:
    Applications: Bioassay
  177. hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye
    Authors: K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller
    Int J Mol Sci, 2019-02-16;20(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1? Protein during Virion-Mediated Activation of the AIM2 Inflammasome
    Authors: S Botto, J Abraham, N Mizuno, K Pryke, B Gall, I Landais, DN Streblow, KJ Fruh, VR DeFilippis
    MBio, 2019-02-12;10(1):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis
    Authors: HG Lee, JU Lee, DH Kim, S Lim, I Kang, JM Choi
    Nat Commun, 2019-02-12;10(1):709.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis
    Authors: BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla
    Sci Rep, 2019-02-04;9(1):1149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
    Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
    Cancer Res., 2019-02-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes
    Authors: B Crifo, B Schaible, E Brown, DN Halligan, CC Scholz, SF Fitzpatric, A Kirwan, HM Roche, M Criscuoli, A Naldini, H Giffney, D Crean, A Blanco, MA Cavadas, EP Cummins, Z Fabian, CT Taylor
    J. Immunol., 2019-01-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Rifamycin SV exhibits strong anti-inflammatory in�vitro activity through pregnane X receptor stimulation and NF?B inhibition
    Authors: C Rosette, FJ Agan, N Rosette, L Moro, A Mazzetti, C Hassan, M Gerloni
    Drug Metab. Pharmacokinet., 2019-01-17;34(3):172-180.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis
    Authors: MR Tanner, MW Pennington, SS Chauhan, T Laragione, PS Gulko, C Beeton
    Arthritis Res. Ther., 2019-01-07;21(1):6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. In�Vitro Expansion of Anti-viral T Cells from Cord Blood by Accelerated Co-cultured Dendritic Cells
    Authors: K Kuranda, S Caillat-Zu, S You, R Mallone
    Mol Ther Methods Clin Dev, 2018-12-31;13(0):112-120.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Intravascular heavy chain-modification of hyaluronan during endotoxic shock
    Authors: K Ni, A Gill, D Cao, K Koike, KS Schweitzer, S Garantziot, I Petrache
    Biochem Biophys Rep, 2018-12-26;17(0):114-121.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Tumor necrosis factor-like weak inducer of apoptosis induces inflammation in Graves' orbital fibroblasts
    Authors: SJ Lee, J Kim, J Ko, EJ Lee, HJ Koh, JS Yoon
    PLoS ONE, 2018-12-21;13(12):e0209583.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4
    Authors: R Kolb, P Kluz, ZW Tan, N Borcherdin, N Bormann, A Vishwakarm, L Balcziak, P Zhu, BS Davies, F Gourronc, LZ Liu, X Ge, BH Jiang, K Gibson-Cor, A Klingelhut, NS Tan, Y Zhu, FS Sutterwala, X Shen, W Zhang
    Oncogene, 2018-12-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Varicella zoster virus differentially alters morphology and suppresses proinflammatory cytokines in primary human spinal cord and hippocampal astrocytes
    Authors: AN Bubak, CN Como, AM Blackmon, D Jones, MA Nagel
    J Neuroinflammation, 2018-11-15;15(1):318.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Phosphorylation and inhibition of ceramide kinase by protein kinase C-?: Their changes by serine residue mutations
    Authors: H Takahashi, H Ashikawa, H Nakamura, T Murayama
    Cell. Signal., 2018-11-15;0(0):.
    Species: Human
    Sample Types:
    Applications: Cell Culture
  191. ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells
    Authors: W Chen, MS Nyuydzefe, JM Weiss, J Zhang, SD Waksal, A Zanin-Zhor
    Sci Rep, 2018-11-09;8(1):16636.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  192. The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
    Authors: L Kasper, A König, PA Koenig, MS Gresnigt, J Westman, RA Drummond, MS Lionakis, O Gro beta, J Ruland, JR Naglik, B Hube
    Nat Commun, 2018-10-15;9(1):4260.
  193. Effect of Polydeoxyribonucleotide on Angiogenesis and Wound Healing in an In Vitro Model of Osteoarthritis
    Authors: A Baek, Y Kim, JW Lee, SC Lee, SR Cho
    Cell Transplant, 2018-10-12;0(0):9636897188041.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma
    Authors: U Painuly, V Ramakrishn, T Kimlinger, L Wellik, J Haug, W Gonsalves, L Bi, Z Huang, SV Rajkumar, S Kumar
    Oncotarget, 2018-10-02;9(77):34582-34594.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Plasminogen-Dependent Collagenolytic Properties of Staphylococcus aureus in Collagen Gel Cultures of Human Corneal Fibroblasts
    Authors: K Sugioka, A Kodama-Tak, T Sato, K Okada, J Murakami, AM Park, H Mishima, Y Shimomura, S Kusaka, T Nishida
    Invest. Ophthalmol. Vis. Sci., 2018-10-01;59(12):5098-5107.
    Species: Human
    Sample Types: Whole Cells
  196. Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model
    Authors: GH Yang, C Zhang, N Wang, Y Meng, YS Wang
    Cytokine, 2018-09-28;111(0):350-356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. NCOA3 Loss Disrupts Molecular Signature of Chondrocytes and Promotes Posttraumatic Osteoarthritis Progression
    Authors: B Zhang, Z Li, W Wang, J Guo, S Kang, S Liu, H Li, D Wang, X Qi
    Cell. Physiol. Biochem., 2018-09-27;49(6):2396-2413.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells
    Authors: KA Cavassani, RJ Meza, DM Habiel, JF Chen, A Montes, M Tripathi, GA Martins, TR Crother, S You, CM Hogaboam, N Bhowmick, EM Posadas
    Cancer Med, 2018-08-09;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  199. ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
    Sci Rep, 2018-08-06;8(1):11720.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
    Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
    Physiol Rep, 2018-08-01;6(16):e13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation
    Authors: C Angiolilli, PA Kabala, AM Grabiec, M Rossato, WS Lai, G Fossati, P Mascagni, C Steinkühle, PJ Blackshear, KA Reedquist, DL Baeten, TRDJ Radstake
    Arthritis Res. Ther., 2018-07-20;20(1):148.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Targeting TRAF6 E3 ligase activity with a small molecule inhibitor combats autoimmunity
    Authors: JK Brenke, GM Popowicz, K Schorpp, I Rothenaign, M Roesner, I Meininger, C Kalinski, L Ringelstet, O R'kyek, G Jürjens, M Vincendeau, O Plettenbur, M Sattler, D Krappmann, K Hadian
    J. Biol. Chem., 2018-06-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
    Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
    Cell Death Dis, 2018-06-04;9(6):665.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth
    Authors: A Kock, K Larsson, F Bergqvist, N Eissler, LHM Elfman, J Raouf, M Korotkova, JI Johnsen, PJ Jakobsson, P Kogner
    EBioMedicine, 2018-05-24;32(0):84-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Anisakis pegreffii impacts differentiation and function of human dendritic cells
    Authors: C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti
    Parasite Immunol., 2018-05-01;0(0):e12527.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes
    Authors: MW Tang, B Malvar Fer, SP Newsom, JD van Buul, TRDJ Radstake, DL Baeten, PP Tak, KA Reedquist, S García
    Rheumatology (Oxford), 2018-05-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Stimulation
  207. Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
    Authors: E Vorkapic, A Kunath, D Wågsäter
    Mol Med Rep, 2018-04-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. RIPK1 downregulation in keratinocyte enhances TRAIL signaling in psoriasis
    Authors: N Saito, M Honma, T Shibuya, S Iinuma, S Igawa, M Kishibe, A Ishida-Yam
    J. Dermatol. Sci., 2018-04-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Prolactin protects against cytokine-induced beta cell death by NFkB and JNK inhibition
    Authors: TR Nardelli, EC Vanzela, KC Benedicto, F Brozzi, A Fujita, AK Cardozo, D Eizirik, AC Boschero, F Ortis
    J. Mol. Endocrinol., 2018-04-09;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Canagliflozin inhibits interleukin-1?-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms
    Authors: SJ Mancini, D Boyd, OJ Katwan, A Strembitsk, TA Almabrouk, S Kennedy, TM Palmer, IP Salt
    Sci Rep, 2018-03-27;8(1):5276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
    Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
    Sci Rep, 2018-03-23;8(1):5126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Methotrexate inhibits effects of platelet-derived growth factor and interleukin-1? on rheumatoid arthritis fibroblast-like synoviocytes
    Authors: B Bergström, H Carlsten, AH Ekwall
    Arthritis Res. Ther., 2018-03-20;20(1):49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Expression and regulation of alarmin cytokine IL-1? in human retinal pigment epithelial cells
    Authors: ZM Bian, MG Field, SG Elner, VM Elner
    Exp. Eye Res., 2018-03-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Sulforaphane rescues amyloid-? peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
    Authors: KA Jhang, JS Park, HS Kim, YH Chong
    J Neuroinflammation, 2018-03-12;15(1):75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. The Vasoreparative Function of Myeloid Angiogenic Cells Is Impaired in Diabetes Through the Induction of IL1?
    Authors: SEJ Chambers, CL O'Neill, J Guduric-Fu, KJ McLoughlin, A Liew, AM Egan, T O'Brien, AW Stitt, RJ Medina
    Stem Cells, 2018-03-09;36(6):834-843.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Interactome analysis of transforming growth factor-?-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
    Authors: O Sokolova, T Kähne, K Bryan, M Naumann
    Oncotarget, 2018-02-21;9(18):14366-14381.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Distinct CD40L receptors mediate inflammasome activation and secretion of IL-1? and MCP-1 in cultured human retinal pigment epithelial cells
    Authors: ZM Bian, MG Field, SG Elner, JM Kahlenberg, VM Elner
    Exp. Eye Res., 2018-02-16;170(0):29-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  218. Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models
    Authors: A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, M Ding, J Synnergren, H Zetterberg, G Brolén, R Hicks, A Herland, A Falk
    Stem Cell Reports, 2018-02-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Galectin-3 is an amplifier of the interleukin-1?-mediated inflammatory response in corneal keratinocytes
    Authors: Y Uchino, AM Woodward, J Mauris, K Peterson, P Verma, UJ Nilsson, J Rajaiya, P Argüeso
    Immunology, 2018-02-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
    Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
    Diabetologia, 2018-02-14;0(0):.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  221. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
    Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
    Neurobiol. Dis., 2018-02-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  222. Virus-like infection induces human ? cell dedifferentiation
    Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
    JCI Insight, 2018-02-08;3(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Depletion of aquaporin 1 decreased ADAMTS?4 expression in human chondrocytes
    Authors: M Haneda, S Hayashi, T Matsumoto, S Hashimoto, K Takayama, N Chinzei, S Kihara, K Takeuchi, K Nishida, R Kuroda
    Mol Med Rep, 2018-02-02;17(4):4874-4882.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials
    Authors: H Fraser, N Safinia, N Grageda, S Thirkell, K Lowe, LJ Fry, C Scottá, A Hope, C Fisher, R Hilton, D Game, P Harden, A Bushell, K Wood, RI Lechler, G Lombardi
    Mol Ther Methods Clin Dev, 2018-01-31;8(0):198-209.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway
    Authors: F Zhang, G Liu, D Li, C Wei, J Hao
    J. Immunol., 2018-01-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
    Authors: WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson
    Front Immunol, 2018-01-29;9(0):80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  227. Regulation of IL-1 signaling through control of focal adhesion assembly
    Authors: Q Wang, J Delcorde, T Tang, GP Downey, CA McCulloch
    FASEB J., 2018-01-22;0(0):fj201700966R.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
    Authors: TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley
    J Innate Immun, 2018-01-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro
    Authors: M Medelin, V Giacco, A Aldinucci, G Castronovo, E Bonechi, A Sibilla, M Tanturli, M Torcia, L Ballerini, F Cozzolino, C Ballerini
    Mol Brain, 2018-01-15;11(1):3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  230. BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity
    Authors: RJW Arts, SJCFM Moorlag, B Novakovic, Y Li, SY Wang, M Oosting, V Kumar, RJ Xavier, C Wijmenga, LAB Joosten, CBEM Reusken, CS Benn, P Aaby, MP Koopmans, HG Stunnenber, R van Crevel, MG Netea
    Cell Host Microbe, 2018-01-10;23(1):89-100.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  231. EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells
    Authors: YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo
    PLoS ONE, 2018-01-03;13(1):e0190638.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
    Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
    J Cancer, 2018-01-01;9(2):367-374.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Nitric Oxide Mediates Crosstalk between Interleukin 1? and WNT Signaling in Primary Human Chondrocytes by Reducing DKK1 and FRZB Expression
    Authors: L Zhong, S Schivo, X Huang, J Leijten, M Karperien, JN Post
    Int J Mol Sci, 2017-11-22;18(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Proinflammatory cytokine interferon-? increases the expression of BANCR, a long non-coding RNA, in retinal pigment epithelial cells
    Authors: RK Kutty, W Samuel, T Duncan, O Postnikova, C Jaworski, CN Nagineni, TM Redmond
    Cytokine, 2017-10-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Healing of Preterm Ruptured Fetal Membranes
    Authors: H Mogami, A Hari Kisho, Y Akgul, RA Word
    Sci Rep, 2017-10-13;7(1):13139.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017-09-07;2(17):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models
    Authors: A Steinert, I Linas, B Kaya, M Ibrahim, A Schlitzer, P Hruz, K Radulovic, L Terraccian, AJ Macpherson, JH Niess
    J. Immunol., 2017-09-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. The Role of Inflammation in ?-cell Dedifferentiation
    Authors: TM Nordmann, E Dror, F Schulze, S Traub, E Berishvili, C Barbieux, M Böni-Schne, MY Donath
    Sci Rep, 2017-07-24;7(1):6285.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting Alone
    Authors: L Ding, JA Buckwalter, JA Martin
    Mediators Inflamm., 2017-07-18;2017(0):2642549.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  240. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3496-3505.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection
    Authors: R Connor, LD Jones, X Qiu, J Thakar, SB Maggirwar
    J. Leukoc. Biol., 2017-06-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
    Authors: L Šenolt, K Prajzlerov, H Hulejová, B Šumová, M Filková, D Veigl, K Pavelka, J Vencovský
    Cytokine, 2017-06-26;97(0):187-192.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy
    Authors: J Ye, Y Wang, X Liu, L Li, A Opejin, EC Hsueh, H Luo, T Wang, D Hawiger, G Peng
    J. Immunol., 2017-06-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition
    Authors: E Forcade, K Paz, R Flynn, B Griesenaue, T Amet, W Li, L Liu, G Bakoyannis, D Jiang, HW Chu, M Lobera, J Yang, DS Wilkes, J Du, K Gartlan, GR Hill, KP MacDonald, EL Espada, P Blanco, JS Serody, J Koreth, CS Cutler, JH Antin, RJ Soiffer, J Ritz, S Paczesny, BR Blazar
    JCI Insight, 2017-06-15;2(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism
    Authors: J Shen, C Wang, D Li, T Xu, J Myers, JM Ashton, T Wang, MJ Zuscik, A McAlinden, RJ O'Keefe
    JCI Insight, 2017-06-15;2(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
    Authors: NT Hogan, MB Whalen, LK Stolze, NK Hadeli, MT Lam, JR Springstea, CK Glass, CE Romanoski
    Elife, 2017-06-06;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
    Authors: R Santos, KC Vadodaria, BN Jaeger, A Mei, S Lefcochilo, APD Mendes, G Erikson, M Shokhirev, L Randolph-M, C Fredlender, S Dave, R Oefner, C Fitzpatric, M Pena, JJ Barron, M Ku, AM Denli, BE Kerman, P Charnay, JR Kelsoe, MC Marchetto, FH Gage
    Stem Cell Reports, 2017-06-06;8(6):1757-1769.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. RANK/RANKL/OPG system in the intervertebral disc
    Authors: N Takegami, K Akeda, J Yamada, T Sano, K Murata, J Huang, K Masuda, A Sudo
    Arthritis Res. Ther., 2017-06-02;19(1):121.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis
    Authors: F Pan, H Xiang, J Yan, L Hong, L Zhang, Y Liu, X Feng, C Cai
    Scand. J. Immunol., 2017-06-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes
    Authors: D Moulin, V Salone, M Koufany, T Clément, I Behm-Ansma, C Branlant, B Charpentie, JY Jouzeau
    Biomed Res Int, 2017-05-22;2017(0):9792512.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells
    Authors: J Geng, S Yu, H Zhao, X Sun, X Li, P Wang, X Xiong, L Hong, C Xie, J Gao, Y Shi, J Peng, RL Johnson, N Xiao, L Lu, J Han, D Zhou, L Chen
    Nat. Immunol., 2017-05-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
    Authors: A Alquraini, M Jamal, L Zhang, T Schmidt, GD Jay, KA Elsaid
    Arthritis Res. Ther., 2017-05-08;19(1):89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy
    Authors: J Ko, MK Chae, JH Lee, EJ Lee, JS Yoon
    Invest. Ophthalmol. Vis. Sci., 2017-05-01;58(5):2544-2553.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Microglia-derived IL-1? promotes chemokine expression by M�ller cells and RPE in focal retinal degeneration
    Authors: R Natoli, N Fernando, M Madigan, JA Chu-Tan, K Valter, J Provis, M Rutar
    Mol Neurodegener, 2017-04-24;12(1):31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017-04-17;8(1):79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  256. A functional DC cross talk promotes human ILC homeostasis in humanized mice
    Authors: S Lopez-Last, G Masse-Rans, O Fiquet, S Darche, N Serafini, Y Li, M Dusséaux, H Strick-Mar, JP Di Santo
    Blood Adv, 2017-04-06;1(10):601-614.
    Species: Human
    Sample Types: Whole Cells
  257. Siglec-7 restores ?-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes
    Authors: G Dharmadhik, K Stolz, M Hauke, NG Morgan, A Varki, E de Koning, S Kelm, K Maedler
    Sci Rep, 2017-04-05;7(0):45319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer
    Authors: A Rynne-Vida, CL Au-Yeung, JA Jiménez-He, ML Pérez-Loza, L Cremades-J, C Bárcena, I Cristóbal-, C Fernández-, TL Yeung, SC Mok, P Sandoval, M López-Cabr
    J. Pathol, 2017-04-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific
    Authors: N Nishijima, T Hirai, K Misato, M Aoyama, E Kuroda, KJ Ishii, K Higashisak, Y Yoshioka, Y Tsutsumi
    Front Immunol, 2017-04-03;8(0):379.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells
    Authors: A Camelo, G Rosignoli, Y Ohne, RA Stewart, C Overed-Say, MA Sleeman, RD May
    Blood Adv, 2017-03-30;1(10):577-589.
    Species: Human
    Sample Types: Whole Cells
  261. Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo
    Authors: D Li, N Liu, HH Zhao, X Zhang, H Kawano, L Liu, L Zhao, HP Li
    J Neuroinflammation, 2017-03-29;14(1):67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  262. IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas
    Authors: BX Ross, N Gao, X Cui, TJ Standiford, J Xu, FX Yu
    J. Immunol, 2017-03-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients
    Authors: V Ruiz-Carpi, P Sandoval, A Aguilera, P Albar-Vizc, ML Perez-Loza, GT González-M, A Acuña-Ruiz, J García-Can, P Botías, MA Bajo, R Selgas, JA Sánchez-To, J Passlick-D, D Piecha, J Büchel, S Steppan, M López-Cabr
    Sci Rep, 2017-03-22;7(0):44941.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  264. In�vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells
    Authors: Y Kokubu, T Yamaguchi, K Kawabata
    Biochem. Biophys. Res. Commun, 2017-03-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Comparison of the effects of cefazolin and ceftriaxone on canine chondrocyte culture
    Authors: P Siengdee, W Pradit, T Euppayo, S Chomdej, K Nganvongpa
    J. Vet. Pharmacol. Ther, 2017-03-19;0(0):.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  266. ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells
    Authors: HJ Lee, SN Kim, MS Jeon, T Yi, SU Song
    Sci Rep, 2017-03-14;7(0):44486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation
    Authors: WC Chu, S Zhang, TJ Sng, YJ Ong, WL Tan, VY Ang, CB Foldager, WS Toh
    Int J Oral Sci, 2017-03-10;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Chondroprotective�Effects�of�Ginsenoside�Rg1�in� Human�Osteoarthritis�Chondrocytes�and�a�Rat�Model� of�Anterior�Cruciate�Ligament�Transection
    Authors: W Cheng, J Jing, Z Wang, D Wu, Y Huang
    Nutrients, 2017-03-10;9(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  269. The symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis inhibits IL-1?-induced inflammation in human fetal enterocytes via toll receptors 2 and 4
    Authors: F Jiang, D Meng, M Weng, W Zhu, W Wu, D Kasper, WA Walker
    PLoS ONE, 2017-03-09;12(3):e0172738.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations
    Authors: C Guntermann, A Piaia, ML Hamel, D Theil, T Rubic-Schn, A Del Rio-Es, L Dong, A Billich, K Kaupmann, J Dawson, K Hoegenauer, D Orain, S Hintermann, R Stringer, DD Patel, A Doelemeyer, M Deurinck, J Schümann
    JCI Insight, 2017-03-09;2(5):e91127.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-?B-Activating Factors through Direct Downregulation of IKK? and IKK?
    Authors: MH Hancock, LM Hook, J Mitchell, JA Nelson
    MBio, 2017-03-07;8(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption
    Authors: CY Chiu, SC Su, WL Fan, SH Lai, MH Tsai, SH Chen, KS Wong, WH Chung
    Sci Rep, 2017-02-24;7(0):43469.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity
    Authors: L Israel, Y Wang, K Bulek, E Della Mina, Z Zhang, V Pedergnana, M Chrabieh, NA Lemmens, V Sancho-Shi, M Descatoire, T Lasseau, E Israelsson, L Lorenzo, L Yun, A Belkadi, A Moran, LE Weisman, F Vandenesch, F Batteux, S Weller, M Levin, J Herberg, A Abhyankar, C Prando, Y Itan, WJB van Wamel, C Picard, L Abel, D Chaussabel, X Li, B Beutler, PD Arkwright, JL Casanova, A Puel
    Cell, 2017-02-23;168(5):789-800.e10.
    Species: Human
    Sample Types: Whole Blood, Whole Cells
    Applications: Bioassay, Cell Culture
  274. Soya-cerebroside, an extract of Cordyceps militaris, suppresses monocyte migration and prevents cartilage degradation in inflammatory animal models
    Authors: SC Liu, CP Chiu, CH Tsai, CY Hung, TM Li, YC Wu, CH Tang
    Sci Rep, 2017-02-22;7(0):43205.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  275. Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results
    Authors: A Riba, M Emmenlauer, A Chen, F Sigoillot, F Cong, C Dehio, J Jenkins, M Zavolan
    Cell Syst, 2017-02-15;4(2):182-193.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes
    Authors: Z Zhang, Q He, Y Tao, J Guo, F Xu, LY Wu, YS Zhao, D Wu, LY Zhou, JY Su, LX Song, C Xiao, X Li, CK Chang
    Am J Transl Res, 2017-02-15;9(2):454-465.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates
    Authors: MM Shikhagaie, ÅK Björklund, J Mjösberg, JS Erjefält, AS Cornelisse, XR Ros, SM Bal, JJ Koning, RE Mebius, M Mori, M Bruchard, B Blom, H Spits
    Cell Rep, 2017-02-14;18(7):1761-1773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells
    Authors: M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney
    Clin. Cancer Res, 2017-02-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation
    Authors: A Smole, D Lain??ek, U Bezeljak, S Horvat, R Jerala
    Mol. Ther, 2017-01-04;25(1):102-119.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  280. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017-01-01;0(0):0.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner.
    Authors: Elias S, Schmidt A, Kannan V, Andersson J, Tegner J
    Front Immunol, 2016-12-23;7(0):603.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  282. Analysis of CXCR5(+)Th17 cells in relation to disease activity and TNF inhibitor therapy in Rheumatoid Arthritis
    Sci Rep, 2016-12-22;6(0):39474.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
    Authors: Shailesh Dudhgaonka
    J. Immunol, 2016-12-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016-12-01;7(1):175.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
    Sci Rep, 2016-12-01;6(0):37977.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation
    Authors: Andrea Todisco
    Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population
    Authors: Derek N J Hart
    J. Immunol., 2016-11-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
  288. Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models
    Authors: Nathalie Castex-Riz
    Clin Cosmet Investig Dermatol, 2016-11-10;9(0):421-434.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations
    Authors: Robert Sabat
    Mediators Inflamm., 2016-10-23;2016(0):4097574.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
    Aging Cell, 2016-09-22;0(0):.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
    J Biol Chem, 2016-09-20;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue
    J Immunol, 2016-09-19;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  293. Negative regulation of NF-?B p65 activity by serine 536 phosphorylation.
    Authors: Jean-Philippe Pradère, Céline Hernandez, Christiane Koppe, Richard A Friedman, Tom Luedde, Robert F Schwabe
    Science Signaling, 2016-08-23;0(0):1937-9145.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  294. DUSP1 maintains IRF1 and leads to increased expression of IRF1-dependent genes: A mechanism promoting glucocorticoid-insensitivity
    J Biol Chem, 2016-08-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Identification of microRNA-181a-5p and microRNA-4454 as mediators of facet cartilage degeneration
    JCI Insight, 2016-08-04;1(12):e86820.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Innate lymphoid cells are expanded and functionally altered in chronic lymphocytic leukemia
    Authors: I de Weerdt, V van Hoeven, JM Munneke, S Endstra, T Hofland, MD Hazenberg, AP Kater
    Haematologica, 2016-08-04;101(11):e461-e464.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Human Mesenchymal Stem Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-Dependent Mechanism
    Stem Cells Transl Med, 2016-07-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Fibroblasts profiling in scarring trachoma identifies IL-6 as a functional component of a fibroblast-macrophage pro-fibrotic and pro-inflammatory feedback loop
    Authors: Jenny Z Kechagia
    Sci Rep, 2016-06-20;6(0):28261.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
    Authors: Chan-Mi Lee
    Cell Biosci, 2016-06-16;6(0):43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  300. Structural and functional attributes of the Interleukin-36 receptor
    Authors: Guanghui Yi
    J Biol Chem, 2016-06-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Expression of human gene coding ROR?T receptor depends on the Sp2 transcription factor
    Authors: Marcin Ratajewski
    J Leukoc Biol, 2016-06-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  302. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
    J Immunol, 2016-05-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Silk-based blood stabilization for diagnostics
    Proc Natl Acad Sci USA, 2016-05-09;113(21):5892-7.
    Species: Human
    Sample Types: Urine
    Applications: Bioassay
  304. Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation
    Sci Rep, 2016-05-04;6(0):25171.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7
    Authors: MM Halpert, V Konduri, D Liang, Y Chen, JB Wing, S Paust, JM Levitt, WK Decker
    Stem Cells Dev., 2016-05-02;25(10):774-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis
    PLoS ONE, 2016-04-28;11(4):e0154107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  307. 4-methylumbelliferone diminishes catabolically-activated articular chondrocytes and cartilage explants via a mechanism independent of hyaluronan inhibition
    J Biol Chem, 2016-04-25;0(0):.
    Species: Bovine, Human
    Sample Types: Whole Cells
    Applications: Bioassay
  308. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs
    Authors: SM Bal, JH Bernink, M Nagasawa, J Groot, MM Shikhagaie, K Golebski, CM van Drunen, R Lutter, RE Jonkers, P Hombrink, M Bruchard, J Villaudy, JM Munneke, W Fokkens, JS Erjefält, H Spits, XR Ros
    Nat Immunol, 2016-04-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis
    Authors: M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu, D Ren, B Yu, L Zheng, X Hu, W Shi, J Xu
    Stem Cell Res Ther, 2016-04-23;7(1):63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Ubiquitin D regulates IRE1?/JNK-dependent apoptosis in pancreatic beta cells
    Authors: F Brozzi, S Gerlo, FA Grieco, M Juusola, A Balhuizen, S Lievens, C Gysemans, M Bugliani, C Mathieu, P Marchetti, J Tavernier, DL Eizirik
    J Biol Chem, 2016-04-04;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  311. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
    Authors: R Flynn, K Paz, J Du, DK Reichenbac, PA Taylor, A Panoskalts, A Vulic, L Luznik, KK MacDonald, GR Hill, MS Nyuydzefe, JM Weiss, W Chen, A Trzeciak, JS Serody, EG Aguilar, WJ Murphy, I Maillard, D Munn, J Koreth, CS Cutler, JH Antin, J Ritz, SD Waksal, A Zanin-Zhor, BR Blazar
    Blood, 2016-03-16;127(17):2144-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. NF-?B Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors
    Authors: Gwendolyn Sowa
    Phys Ther, 2016-02-18;96(5):704-11.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
    Authors: Guo Z, Zheng L, Liao X, Geller D
    PLoS ONE, 2016-01-11;11(1):e0146640.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis
    Authors: BR Yoon, YH Chung, SJ Yoo, K Kawara, J Kim, IS Yoo, CG Park, SW Kang, WW Lee
    J. Biol. Chem, 2015-12-23;291(8):4048-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Ultraviolet light converts propranolol, a nonselective beta-blocker and potential lupus-inducing drug, into a proinflammatory AhR ligand.
    Authors: Dorgham K, Amoura Z, Parizot C, Arnaud L, Frances C, Pionneau C, Devilliers H, Pinto S, Zoorob R, Miyara M, Larsen M, Yssel H, Gorochov G, Mathian A
    Eur J Immunol, 2015-10-16;45(11):3174-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways.
    Authors: Mattiola I, Pesant M, Tentorio P, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D
    J Immunol, 2015-08-14;195(6):2818-28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor.
    Authors: Saha S, Singh D, Raymond E, Ganesan R, Caviness G, Grimaldi C, Woska J, Mennerich D, Brown S, Mbow M, Kao C
    J Biol Chem, 2015-08-12;290(39):23997-4006.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Pro-Inflammatory Cytokine IL-1beta Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma.
    Authors: Sun Y, Zhu D, Wang G, Wang D, Zhou H, Liu X, Jiang M, Liao L, Zhou Z, Hu J
    PLoS ONE, 2015-07-15;10(7):e0132677.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  319. IL-4 Downregulates IL-1beta and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine.
    Authors: Onderdijk A, Baerveldt E, Kurek D, Kant M, Florencia E, Debets R, Prens E
    J Immunol, 2015-07-13;195(4):1744-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation.
    Authors: Ahn Y, Weeres M, Neulen M, Choi J, Kang S, Heo D, Bergerson R, Blazar B, Miller J, Verneris M
    Eur J Immunol, 2015-06-22;45(8):2335-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
    Authors: Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D
    J Transl Med, 2015-06-20;13(0):197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Eupatilin Exerts Antinociceptive and Chondroprotective Properties in a Rat Model of Osteoarthritis by Downregulating Oxidative Damage and Catabolic Activity in Chondrocytes.
    Authors: Jeong J, Moon S, Jhun J, Yang E, Cho M, Min J
    PLoS ONE, 2015-06-17;10(6):e0130882.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
    Authors: Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov H, Hopkins G, DU L, Belkadi A, Chrabieh M, Itan Y, Picard C, Fournet J, Eibel H, Tsitsikov E, Pai S, Abel L, Al-Herz W, Casanova J, Israel A, Notarangelo L
    J Exp Med, 2015-05-25;212(6):939-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Generation of articular chondrocytes from human pluripotent stem cells.
    Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
    Nat Biotechnol, 2015-05-11;33(6):638-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  325. Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.
    Authors: Brand O, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson A, Hill A, Jablons D, Wolters P, Lou J, Marks J, Baron J, Nishimura S
    J Biol Chem, 2015-04-27;290(23):14717-28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis.
    Authors: Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, Ikinciogullari A, Dogu F, Belkadi A, Levy R, Migaud M, Boisson B, Bolze A, Itan Y, Goudin N, Cottineau J, Picard C, Abel L, Bustamante J, Casanova J, Puel A
    J Exp Med, 2015-04-27;212(5):619-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer.
    Authors: Comblain F, Sanchez C, Lesponne I, Balligand M, Serisier S, Henrotin Y
    PLoS ONE, 2015-03-23;10(3):e0121654.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
    Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
    Nat Med, 2015-03-16;21(4):363-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Adrenal steroids modulate the immune response during Brucella abortus infection by a mechanism that depends on the regulation of cytokine production.
    Authors: Gentilini M, Velasquez L, Barrionuevo P, Arriola Benitez P, Giambartolomei G, Delpino M
    Infect Immun, 2015-03-02;83(5):1973-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  330. The expression and regulation of chemerin in the epidermis.
    Authors: Banas M, Zegar A, Kwitniewski M, Zabieglo K, Marczynska J, Kapinska-Mrowiecka M, LaJevic M, Zabel B, Cichy J
    PLoS ONE, 2015-02-06;10(2):e0117830.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  331. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
    Authors: Herova M, Schmid M, Gemperle C, Hersberger M
    J Immunol, 2015-01-30;194(5):2330-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting beta(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.
    Authors: Rider C, Shah S, Miller-Larsson A, Giembycz M, Newton R
    PLoS ONE, 2015-01-27;10(1):e0116773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Differential expression of the immunosuppressive enzyme IL4I1 in human induced Aiolos+, but not natural Helios+, FOXP3+ Treg cells.
    Authors: Scarlata C, Celse C, Pignon P, Ayyoub M, Valmori D
    Eur J Immunol, 2015-01-16;45(2):474-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Short term exposure of beta cells to low concentrations of interleukin-1beta improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.
    Authors: Arous C, Ferreira P, Dermitzakis E, Halban P
    J Biol Chem, 2015-01-13;290(10):6653-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta.
    Authors: Yan X, Jiang E, Weng H
    J Neuroinflammation, 2015-01-09;12(0):222.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  336. Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.
    Authors: Li H, Richert-Spuhler L, Evans T, Gillis J, Connole M, Estes J, Keele B, Klatt N, Reeves R
    PLoS Pathog, 2014-12-11;10(12):e1004551.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Interleukin-1 beta enhances human multipotent mesenchymal stromal cell proliferative potential and their ability to maintain hematopoietic precursor cells.
    Authors: Bigildeev A, Zezina E, Shipounova I, Drize N
    Cytokine, 2014-11-24;71(2):246-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  338. Anti-apoptotic NF-kappaB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production.
    Authors: Muller I, Beissert S, Kulms D
    J Invest Dermatol, 2014-11-07;135(3):851-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  339. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
    Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
    Mol Ther, 2014-11-04;23(2):387-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. 1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.
    Authors: Van Belle T, Vanherwegen A, Feyaerts D, De Clercq P, Verstuyf A, Korf H, Gysemans C, Mathieu C
    PLoS ONE, 2014-10-03;9(10):e109194.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  341. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets.
    Authors: Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, Wei Y, Ouyang F, Chen D, Wu Y, Lao X, Deng H, Zheng L
    J Clin Invest, 2014-09-17;124(10):4657-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  342. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
    Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
    PLoS ONE, 2014-09-03;9(9):e106673.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Cyclic phosphatidic acid relieves osteoarthritis symptoms.
    Authors: Gotoh M, Nagano A, Tsukahara R, Murofushi H, Morohoshi T, Otsuka K, Murakami-Murofushi K
    Mol Pain, 2014-08-14;10(0):52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Nitric oxide enhances Th9 cell differentiation and airway inflammation.
    Authors: Niedbala W, Besnard A, Nascimento D, Donate P, Sonego F, Yip E, Guabiraba R, Chang H, Fukada S, Salmond R, Schmitt E, Bopp T, Ryffel B, Liew F
    Nat Commun, 2014-08-07;5(0):4575.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
    Authors: Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K
    J Immunol, 2014-07-30;193(5):2297-305.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor gammat (RORgammat) in Th17 cells.
    Authors: Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, Zhang J, Xing Y, Chen Z, Tsun A, Li D, Piccioni M, Zhang Y, Guo Q, Jiang L, Bao L, Lv L, Li B
    J Biol Chem, 2014-07-28;289(37):25546-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
    Authors: Brozzi F, Gerlo S, Grieco F, Nardelli T, Lievens S, Gysemans C, Marselli L, Marchetti P, Mathieu C, Tavernier J, Eizirik D
    J Biol Chem, 2014-07-25;289(30):20677-93.
    Species: Human, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample.
    Authors: Altara, Raffaele, Manca, Marco, Hessel, Marleen, Janssen, Ben J, Struijker-Boudier, Harry H, Hermans, Rob J J, Blankesteijn, W Matthi
    BMC Biotechnol, 2014-07-15;14(0):63.
    Applications: ELISA (Standard)
  349. A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
    Authors: Lewis, Nuruddee, Patnaude, Lori A, Pelletier, Josephin, Souza, Donald J, Lukas, Susan M, King, F James, Hill, Jonathan, Stefanopoulos, Dimitria, Ryan, Kelli, Desai, Sudha, Skow, Donna, Kauschke, Stefan G, Broermann, Andre, Kuzmich, Daniel, Harcken, Christia, Hickey, Eugene R, Modis, Louise K
    PLoS ONE, 2014-06-26;9(6):e100883.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors.
    Authors: Mercer F, Khaitan A, Kozhaya L, Aberg J, Unutmaz D
    J Immunol, 2014-06-23;193(3):1047-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  351. PHLDA1 expression is controlled by an estrogen receptor-NFkappaB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres.
    Authors: Kastrati I, Canestrari E, Frasor J
    Oncogene, 2014-06-23;34(18):2309-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma.
    Authors: Pomianowska E, Sandnes D, Grzyb K, Schjolberg A, Aasrum M, Tveteraas I, Tjomsland V, Christoffersen T, Gladhaug I
    BMC Cancer, 2014-06-09;14(0):413.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  353. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis.
    Authors: Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M, Bogiatzi S, Fernandez M, Touzot M, Bichet J, Reyal F, Paronetto M, Chiricozzi A, Chimenti S, Nasorri F, Cavani A, Kislat A, Homey B, Soumelis V
    J Allergy Clin Immunol, 2014-06-06;134(2):373-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  354. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta.
    Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y
    Am J Physiol Endocrinol Metab, 2014-06-03;307(2):E186-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  355. IL-1beta promotes the differentiation of polyfunctional human CCR6+CXCR3+ Th1/17 cells that are specific for pathogenic and commensal microbes.
    Authors: Duhen T, Campbell D
    J Immunol, 2014-06-02;193(1):120-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Interleukin-33 induces urokinase in human endothelial cells--possible impact on angiogenesis.
    Authors: Stojkovic S, Kaun C, Heinz M, Krychtiuk K, Rauscher S, Lemberger C, de Martin R, Groger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S
    J Thromb Haemost, 2014-06-01;12(6):948-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Glucocorticoid-induced reversal of interleukin-1beta-stimulated inflammatory gene expression in human oviductal cells.
    Authors: Backman S, Kollara A, Haw R, Stein L, Brown T
    PLoS ONE, 2014-05-21;9(5):e97997.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1beta-stimulated production of chemokines and matrix-degrading enzymes in vitro.
    Authors: Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borzi R, Meliconi R
    PLoS ONE, 2014-05-12;9(5):e96925.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  359. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.
    Authors: Kofler D, Marson A, Dominguez-Villar M, Xiao S, Kuchroo V, Hafler D
    J Clin Invest, 2014-05-08;124(6):2513-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
    Authors: Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, Woetmann A, Odum N, Bonefeld C, Geisler C
    PLoS ONE, 2014-05-02;9(5):e96695.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  361. Additive effects of EGF and IL-1beta regulate tumor cell migration and invasion in gastric adenocarcinoma via activation of ERK1/2.
    Authors: Han J, Xie Y, Lan F, Yu Y, Liu W, Chen J, Zheng F, Ouyang X, Lin X, Lin Y, Huang Q, Wang L, Tan J
    Int J Oncol, 2014-04-28;45(1):291-301.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Independent adipogenic and contractile properties of fibroblasts in Graves' orbitopathy: an in vitro model for the evaluation of treatments.
    Authors: Li H, Fitchett C, Kozdon K, Jayaram H, Rose G, Bailly M, Ezra D
    PLoS ONE, 2014-04-21;9(4):e95586.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  363. Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice.
    Authors: Liu J, Ren Y, Kang L, Zhang L
    PLoS ONE, 2014-04-10;9(4):e94912.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  364. Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors.
    Authors: Reed, Daniel M, Foldes, Gabor, Gatheral, Timothy, Paschalaki, Koralia, Lendvai, Zsuzsann, Bagyura, Zsolt, Nemeth, Tamas, Skopal, Judit, Merkely, Bela, Telcian, Aurica G, Gogsadze, Leila, Edwards, Michael, Gough, Peter J, Bertin, John, Johnston, Sebastia, Harding, Sian E, Mitchell, Jane A
    PLoS ONE, 2014-04-01;9(4):e91119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  365. Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.
    Authors: Shah S, King E, Chandrasekhar A, Newton R
    J Biol Chem, 2014-04-01;289(19):13667-79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Composition of innate lymphoid cell subsets in the human skin: enrichment of NCR(+) ILC3 in lesional skin and blood of psoriasis patients.
    Authors: Teunissen M, Munneke J, Bernink J, Spuls P, Res P, Te Velde A, Cheuk S, Brouwer M, Menting S, Eidsmo L, Spits H, Hazenberg M, Mjosberg J
    J Invest Dermatol, 2014-03-21;134(9):2351-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  367. A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.
    Authors: Coward W, Feghali-Bostwick C, Jenkins G, Knox A, Pang L
    FASEB J, 2014-03-20;28(7):3183-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.
    Authors: Ardestani, Amin, Paroni, Federico, Azizi, Zahra, Kaur, Supreet, Khobragade, Vrushali, Yuan, Ting, Frogne, Thomas, Tao, Wufan, Oberholzer, Jose, Pattou, Francois, Kerr Conte, Julie, Maedler, Kathrin
    Nat Med, 2014-03-16;20(4):385-97.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  369. BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic beta-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2.
    Authors: Marroqui L, Santin I, Dos Santos R, Marselli L, Marchetti P, Eizirik D
    Diabetes, 2014-03-07;63(7):2516-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  370. A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist.
    Authors: Gresnigt M, Bozza S, Becker K, Joosten L, Abdollahi-Roodsaz S, van der Berg W, Dinarello C, Netea M, Fontaine T, De Luca A, Moretti S, Romani L, Latge J, van de Veerdonk F
    PLoS Pathog, 2014-03-06;10(3):e1003936.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner.
    Authors: Cushing L, Stochaj W, Siegel M, Czerwinski R, Dower K, Wright Q, Hirschfield M, Casanova J, Picard C, Puel A, Lin L, Rao V
    J Biol Chem, 2014-02-24;289(15):10865-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  372. The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation.
    Authors: Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, Fardel O, Sparfel L
    Eur J Immunol, 2014-02-18;44(5):1330-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
    Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
    PLoS ONE, 2014-02-14;9(2):e88714.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  374. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
    Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
    Mol Ther, 2014-02-05;22(5):999-1007.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  375. CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
    Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
    J Immunol, 2014-02-05;192(5):2449-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  376. IL-1beta-induced activation of p38 promotes metastasis in gastric adenocarcinoma via upregulation of AP-1/c-fos, MMP2 and MMP9.
    Authors: Huang Q, Lan F, Wang X, Yu Y, Ouyang X, Zheng F, Han J, Lin Y, Xie Y, Xie F, Liu W, Yang X, Wang H, Dong L, Wang L, Tan J
    Mol Cancer, 2014-01-31;13(0):18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA.
    Authors: Chiliveru S, Rahbek S, Jensen S, Jorgensen S, Nissen S, Christiansen S, Mogensen T, Jakobsen M, Iversen L, Johansen C, Paludan S
    J Immunol, 2014-01-31;192(5):2395-404.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
    Authors: Haseeb A, Makki M, Haqqi T
    J Biol Chem, 2014-01-27;289(10):6877-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014-01-23;23(6):605-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Pigment epithelium-derived factor (PEDF) suppresses IL-1beta-mediated c-Jun N-terminal kinase (JNK) activation to improve hepatocyte insulin signaling.
    Authors: Gattu A, Birkenfeld A, Iwakiri Y, Jay S, Saltzman M, Doll J, Protiva P, Samuel V, Crawford S, Chung C
    Endocrinology, 2014-01-23;155(4):1373-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  381. TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
    Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
    Proc Natl Acad Sci U S A, 2014-01-13;111(4):1509-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. Interleukin-6 signaling drives fibrosis in unresolved inflammation.
    Authors: Fielding C, Jones G, McLoughlin R, McLeod L, Hammond V, Uceda J, Williams A, Lambie M, Foster T, Liao C, Rice C, Greenhill C, Colmont C, Hams E, Coles B, Kift-Morgan A, Newton Z, Craig K, Williams J, Williams G, Davies S, Humphreys I, O'Donnell V, Taylor P, Jenkins B, Topley N, Jones S
    Immunity, 2014-01-09;40(1):40-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
    Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
    Nat Commun, 2014-01-01;5(0):3199.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  384. High activities of BACE1 in brains with mild cognitive impairment.
    Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
    Am J Pathol, 2014-01-01;184(1):141-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  385. Ginkgo biloba extract individually inhibits JNK activation and induces c-Jun degradation in human chondrocytes: potential therapeutics for osteoarthritis.
    Authors: Ho L, Hung L, Liu F, Hou T, Lin L, Huang C, Lai J
    PLoS ONE, 2013-12-11;8(12):e82033.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  386. IL-32 promotes angiogenesis.
    Authors: Nold-Petry C, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho S, Zepp J, Azam T, Dinkel H, Palmer B, Boisvert W, Cool C, Taraseviciene-Stewart L, Heinhuis B, Joosten L, Dinarello C, Voelkel N, Nold M
    J Immunol, 2013-12-11;192(2):589-602.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  387. Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2.
    Authors: Konradi S, Yasmin N, Haslwanter D, Weber M, Gesslbauer B, Sixt M, Strobl H
    Eur J Immunol, 2013-12-02;44(2):553-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  388. p38-Mediated phosphorylation of Eps15 endocytic adaptor protein.
    Authors: Zhou Y, Tanaka T, Sugiyama N, Yokoyama S, Kawasaki Y, Sakuma T, Ishihama Y, Saiki I, Sakurai H
    FEBS Lett, 2013-11-21;588(1):131-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. Role of Ca2+/calmodulin-dependent kinase II-IRAK1 interaction in LMP1-induced NF-kappaB activation.
    Authors: Kim J, Kim S, Lim S, Kieff E, Song Y
    Mol Cell Biol, 2013-11-18;34(3):325-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.
    Authors: Cucchiarini M, Madry H, Terwilliger E
    J Cell Mol Med, 2013-11-17;18(1):115-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1beta antibody with differential receptor-modulating properties.
    Authors: Issafras H, Corbin J, Goldfine I, Roell M
    J Pharmacol Exp Ther, 2013-11-05;348(1):202-15.
    Applications: Binding Assay, Surface Plasmon Resonance
  392. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes.
    Authors: Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson R, Moritz R, Cunningham A
    PLoS Pathog, 2013-10-17;9(10):e1003700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.
    Authors: Zheng Y, McFarland B, Drygin D, Yu H, Bellis S, Kim H, Bredel M, Benveniste E
    Clin Cancer Res, 2013-09-13;19(23):6484-94.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Cell Culture
  394. Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.
    Authors: Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Muller I
    Eur J Immunol, 2013-07-23;43(10):2741-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  395. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics.
    Authors: Rapicavoli N, Qu K, Zhang J, Mikhail M, Laberge R, Chang H
    Elife, 2013-07-23;2(0):e00762.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  396. CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.
    Authors: Afzali B, Mitchell P, Edozie F, Povoleri G, Dowson S, Demandt L, Walter G, Canavan J, Scotta C, Menon B, Chana P, Khamri W, Kordasti S, Heck S, Grimbacher B, Tree T, Cope A, Taams L, Lechler R, John S, Lombardi G
    Eur J Immunol, 2013-07-03;43(8):2043-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  397. Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands.
    Authors: Stephens G, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M
    Eur J Immunol, 2013-05-08;43(7):1727-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  398. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.
    Authors: Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, Byun J, Kim E, Hwang S, Ju J, Kwok S, Kim H
    Arthritis Rheum, 2013-04-01;65(4):949-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013-03-13;190(8):4196-204.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
    Authors: El-Zaatari M, Kao J, Tessier A, Bai L, Hayes M, Fontaine C, Eaton K, Merchant J
    PLoS ONE, 2013-03-08;8(3):e58935.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Independent and interdependent immunoregulatory effects of IL-27, IFN-beta, and IL-10 in the suppression of human Th17 cells and murine experimental autoimmune encephalomyelitis.
    Authors: Fitzgerald D, Fonseca-Kelly Z, Cullimore M, Safabakhsh P, Saris C, Zhang G, Rostami A
    J Immunol, 2013-03-01;190(7):3225-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.
    Authors: Tang, Xin-Zi, Jo, Juandy, Tan, Anthony, Sandalova, Elena, Chia, Adeline, Tan, Kai Chah, Lee, Kang Hoe, Gehring, Adam J, De Libero, Gennaro, Bertoletti, Antonio
    J Immunol, 2013-02-27;190(7):3142-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  403. Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients.
    Authors: Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, Lopez-Albaitero A, Gibson S, Gooding W, Ferrone S, Ferris R
    Clin Cancer Res, 2013-02-26;19(7):1858-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target.
    Authors: Verjee L, Verhoekx J, Chan J, Krausgruber T, Nicolaidou V, Izadi D, Davidson D, Feldmann M, Midwood K, Nanchahal J
    Proc Natl Acad Sci U S A, 2013-02-19;110(10):E928-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  405. EpCAM modulates NF-kappaB signaling and interleukin-8 expression in breast cancer.
    Authors: Sankpal N, Fleming T, Gillanders W
    Mol Cancer Res, 2013-02-01;11(4):418-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  406. Self double-stranded (ds)DNA induces IL-1beta production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies.
    Authors: Shin M, Kang Y, Lee N, Wahl E, Kim S, Kang K, Lazova R, Kang I
    J Immunol, 2013-01-11;190(4):1407-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  407. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
    Authors: Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israel L, Trevejo-Nunez G, Bogunovic D, Cepika A, MacDuff D, Chrabieh M, Hubeau M, Bajolle F, Debre M, Mazzolari E, Vairo D, Agou F, Virgin H, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet J, Pascual V, Chaussabel D, Notarangelo L, Puel A, Israel A, Casanova J, Picard C
    Nat Immunol, 2012-10-28;13(12):1178-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  408. Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis.
    J. Exp. Med., 2012-10-15;209(11):2033-47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. Mycobacterium tuberculosis infection and tissue factor expression in macrophages.
    Authors: Kothari H, Rao L, Vankayalapati R, Pendurthi U
    PLoS ONE, 2012-09-24;7(9):e45700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  410. Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients.
    Authors: Li J, Mo H, Xiong G, Zhang L, He J, Huang Z, Liu Z, Chen Q, Du Z, Zheng L, Qian C, Zeng Y
    J Biol Chem, 2012-08-14;287(42):35484-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.
    Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K
    Infect Immun, 2012-08-13;80(11):3795-803.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  412. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
    Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
    Nature, 2012-07-26;487(7408):505-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
    J. Exp. Med., 2012-07-16;209(8):1505-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  414. Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS.
    Authors: Flanagan K, Fitzgerald K, Baker J
    PLoS ONE, 2012-07-06;7(7):e40443.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  415. The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells.
    Authors: Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC
    PLoS ONE, 2012-06-22;7(6):e38721.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure.
    Authors: Sikkeland LI, Dahl CP, Ueland T, Andreassen AK, Gude E, Edvardsen T, Holm T, Yndestad A, Gullestad L, Kongerud J, Aukrust P, ØIe E
    PLoS ONE, 2012-05-15;7(5):e36815.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  417. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012-04-18;7(4):e34965.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
    Authors: Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M
    Eur. J. Immunol., 2012-04-01;42(4):936-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  419. Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure.
    Authors: Wilde S, Geiger C, Milosevic S, Mosetter B, Eichenlaub S, Schendel D
    Oncoimmunology, 2012-03-01;1(2):129-140.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  420. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency.
    Authors: Sancho-Shimizu V, Perez de Diego R, Lorenzo L, Halwani R, Alangari A, Israelsson E, Fabrega S, Cardon A, Maluenda J, Tatematsu M, Mahvelati F, Herman M, Ciancanelli M, Guo Y, AlSum Z, Alkhamis N, Al-Makadma AS, Ghadiri A, Boucherit S, Plancoulaine S, Picard C, Rozenberg F, Tardieu M, Lebon P, Jouanguy E, Rezaei N, Seya T, Matsumoto M, Chaussabel D, Puel A, Zhang SY, Abel L, Al-Muhsen S, Casanova JL
    J. Clin. Invest., 2011-11-21;121(12):4889-902.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  421. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2011-11-10;19(10):1035-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  422. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
    Authors: Ramirez-Carrozzi V, Sambandam A, Luis E
    Nat. Immunol., 2011-10-12;12(12):1159-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
    Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
    J Transl Med, 2011-09-13;9(0):151.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis.
    Authors: Hong YS, Moon SJ, Moon S, Joo YB, Joo Y, Jeon CH, Jeon C, Cho ML, Ju JH, Oh HJ, Heo YJ, Heo Y, Park SH, Kim HY, Min JK
    J Korean Med Sci, 2011-09-01;26(9):1132-9.
    Applications: ELISA (Standard)
  425. Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli.
    Authors: Von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T
    J. Immunol., 2011-05-04;186(12):6701-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  426. Cadherin-11 regulates fibroblast inflammation.
    Authors: Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB
    Proc. Natl. Acad. Sci. U.S.A., 2011-05-02;108(20):8402-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  427. B cells as a therapeutic target for IFN-beta in relapsing-remitting multiple sclerosis.
    Authors: Ramgolam VS, Sha Y, Marcus KL, Choudhary N, Troiani L, Chopra M, Markovic-Plese S
    J. Immunol., 2011-03-02;186(0):4518.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  428. IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression.
    Authors: Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE
    J. Immunol., 2011-01-17;186(4):2613-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Cortisol Synthesis in Epidermis Is Induced by IL-1 and Tissue Injury.
    Authors: Vukelic S, Stojadinovic O, Pastar I, Rabach M, Krzyzanowska A, Lebrun E, Davis SC, Resnik S, Brem H, Tomic-Canic M
    J. Biol. Chem., 2011-01-14;286(12):10265-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1beta-mediated diseases.
    Authors: Owyang AM, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, Handa M, Horwitz AH, Roell MK, Haak-Frendscho M, Masat L
    MAbs, 2011-01-01;3(1):49-60.
    Species: Human
    Sample Types: Buffer
    Applications: Binding Assay
  431. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.
    Authors: Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K
    J. Immunol., 2010-12-17;186(2):1119-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  432. Focal increases of fetal macrophages in placentas from pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1.
    Authors: Toti P, Arcuri F, Tang Z, Schatz F, Zambrano E, Mor G, Niven-Fairchild T, Abrahams VM, Krikun G, Lockwood CJ, Guller S
    Am. J. Reprod. Immunol., 2010-11-19;65(5):470-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  433. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.
    Authors: Xu H, Wang X, Pahar B
    J. Immunol., 2010-11-08;185(12):7340-8.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  434. Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
    Authors: Kalliolias GD, Gordon RA, Ivashkiv LB
    J. Immunol., 2010-10-22;185(11):7047-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  435. Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta.
    Authors: Lee B, Kim TH, Jun JB, Yoo DH, Woo JH, Choi SJ, Lee YH, Song GG, Sohn J, Park-Min KH, Ivashkiv LB, Ji JD
    J. Immunol., 2010-10-08;185(10):5926-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  436. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
    Authors: Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA
    FASEB J., 2010-09-08;25(1):409-19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  437. Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
    Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
    J. Immunol., 2010-07-16;185(0):2516-24.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  438. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection.
    Authors: Mengshol JA, Golden-Mason L, Arikawa T
    PLoS ONE, 2010-03-04;5(3):e9504.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.
    Authors: Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ
    Nat. Med., 2010-01-10;16(2):191-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  440. Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts.
    Authors: Nishida A, Andoh A, Imaeda H, Inatomi O, Shiomi H, Fujiyama Y
    Gut, 2009-12-08;59(4):531-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  441. Regulating human Th17 cells via differential expression of IL-1 receptor.
    Authors: Lee WW, Kang SW, Choi J
    Blood, 2009-11-12;115(3):530-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 2009-07-15;284(36):24035-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  443. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
    Authors: Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F
    Nat. Immunol., 2009-07-05;10(8):857-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  444. Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone.
    Authors: Brunton PJ, McKay AJ, Ochedalski T, Piastowska A, Rebas E, Lachowicz A, Russell JA
    J. Neurosci., 2009-05-20;29(20):6449-60.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  445. Interleukin-32 expression in the pancreas.
    Authors: Nishida A, Andoh A, Inatomi O, Fujiyama Y
    J. Biol. Chem., 2009-04-21;284(26):17868-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  446. CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy.
    Authors: Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C
    FASEB J., 2009-04-20;23(9):2928-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  447. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.
    Authors: Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R
    J. Exp. Med., 2009-03-09;206(3):535-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  448. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
    Authors: Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C
    Bone, 2009-03-02;44(6):1143-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  449. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009-03-02;119(10):1424-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  450. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes.
    Authors: Yammani RR, Long D, Loeser RF
    Arthritis Rheum., 2009-03-01;60(3):792-800.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  451. Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.
    Authors: Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ
    Invest. Ophthalmol. Vis. Sci., 2009-01-17;50(6):2702-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  452. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
    Authors: Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Allergy Clin. Immunol., 2008-12-03;123(1):59-66.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  453. Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.
    Authors: Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K
    Clin. Exp. Immunol., 2008-12-01;154(3):384-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  454. Ectopic expression of interleukin-1 receptor type II enhances cell migration through activation of the pre-interleukin 1alpha pathway.
    Authors: Chang SY, Su PF, Lee TC
    Cytokine, 2008-11-20;45(1):32-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  455. Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.
    Authors: Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE
    Proc. Natl. Acad. Sci. U.S.A., 2008-09-16;105(38):14692-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  456. A novel method to establish microglia-free astrocyte cultures: comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia.
    Authors: Crocker SJ, Frausto RF, Whitton JL, Milner R
    Glia, 2008-08-15;56(0):1187-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  457. Endogenous IL-32 controls cytokine and HIV-1 production.
    Authors: Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA
    J. Immunol., 2008-07-01;181(1):557-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  458. Cytokine mRNA induction by interleukin-1beta or tumor necrosis factor alpha in vitro and in vivo.
    Authors: Taishi P, Churchill L, De A, Obal F, Krueger JM
    Brain Res., 2008-06-05;1226(0):89-98.
    Species: Rat
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  459. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils.
    Authors: Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H
    J. Allergy Clin. Immunol., 2008-06-01;121(6):1484-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  460. IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation.
    Authors: Jasny E, Eisenblatter M, Matz-Rensing K, Tenner-Racz K, Tenbusch M, Schrod A, Stahl-Hennig C, Moos V, Schneider T, Racz P, Uberla K, Kaup FJ, Ignatius R
    J. Immunol., 2008-05-15;180(10):6629-39.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  461. Guggulsterone blocks IL-1beta-mediated inflammatory responses by suppressing NF-kappaB activation in fibroblast-like synoviocytes.
    Authors: Lee YR, Lee JH, Noh EM, Kim EK, Song MY, Jung WS, Park SJ, Kim JS, Park JW, Kwon KB, Park BH
    Life Sci., 2008-04-20;82(23):1203-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  462. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
    Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
    J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  463. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.
    Authors: Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S, Kyburz D
    Arthritis Rheum., 2008-04-01;58(4):1001-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  464. Japanese Encephalitis Virus infection induces IL-18 and IL-1beta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death.
    Authors: Das S, Mishra MK, Ghosh J, Basu A
    J. Neuroimmunol., 2008-03-28;195(1):60-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  465. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
    Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
    AIDS Res. Hum. Retroviruses, 2008-03-01;24(3):453-62.
    Applications: ELISA (Standard)
  466. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
    Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
    J. Leukoc. Biol., 2008-02-15;83(5):1181-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  467. Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua.
    Authors: Huang SJ, Chen CP, Schatz F, Rahman M, Abrahams VM, Lockwood CJ
    J. Pathol., 2008-02-01;214(3):328-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  468. Regulation of hepatocyte growth factor secretion by fibroblasts in patients with acute lung injury.
    Authors: Quesnel C, Marchand-Adam S, Fabre A, Marchal-Somme J, Philip I, Lasocki S, Lecon V, Crestani B, Dehoux M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-12-07;294(2):L334-43.
    Species: Human
    Sample Types: BALF
    Applications: Bioassay
  469. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
    Authors: Pfleger C, Schloot N, ter Veld F
    J. Immunol. Methods, 2007-10-22;329(1):214-8.
    Applications: ELISA (Standard)
  470. Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells.
    Authors: Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC
    Clin. Exp. Immunol., 2007-10-09;150(3):567-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  471. Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms.
    Authors: Thiel MJ, Schaefer CJ, Lesch ME, Mobley JL, Dudley DT, Tecle H, Barrett SD, Schrier DJ, Flory CM
    Arthritis Rheum., 2007-10-01;56(10):3347-57.
    Species: Rabbit
    Sample Types: In Vivo
    Applications: In Vivo
  472. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007-09-21;53(11):1990-5.
    Applications: ELISA (Standard)
  473. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques.
    Authors: Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW
    Transplantation, 2007-07-27;84(2):196-206.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  474. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates.
    Authors: Luty WH, Rodeberg D, Parness J, Vyas YM
    J. Immunol., 2007-07-15;179(2):819-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  475. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
    Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
    J. Clin. Invest., 2007-07-01;117(7):1951-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  476. Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease.
    Authors: Shioya M, Nishida A, Yagi Y, Ogawa A, Tsujikawa T, Kim-Mitsuyama S, Takayanagi A, Shimizu N, Fujiyama Y, Andoh A
    Clin. Exp. Immunol., 2007-06-22;149(3):480-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  477. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork.
    Authors: Kelley MJ, Rose AY, Song K, Chen Y, Bradley JM, Rookhuizen D, Acott TS
    Invest. Ophthalmol. Vis. Sci., 2007-06-01;48(6):2634-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  478. Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease.
    Authors: Zhang K, Shan L, Rahman MS, Unruh H, Halayko AJ, Gounni AS
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-05-18;293(2):L375-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  479. Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect.
    Authors: Gesser B, Johansen C, Rasmussen MK, Funding AT, Otkjaer K, Kjellerup RB, Kragballe K, Iversen L
    J. Invest. Dermatol., 2007-05-10;127(9):2129-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  480. IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.
    Authors: Wolk K, Witte E, Hoffmann U, Doecke WD, Endesfelder S, Asadullah K, Sterry W, Volk HD, Wittig BM, Sabat R
    J. Immunol., 2007-05-01;178(9):5973-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  481. Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
    Authors: Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S
    Gut, 2007-04-20;56(9):1257-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  482. Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis.
    Authors: Funding AT, Johansen C, Kragballe K, Iversen L
    J. Invest. Dermatol., 2007-04-12;127(8):2012-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  483. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells.
    Authors: Tacke F, Gabele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Scholmerich J, Schnabl B
    Dig. Dis. Sci., 2007-04-06;52(12):3404-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  484. Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling.
    Authors: Muselet-Charlier C, Roque T, Boncoeur E, Chadelat K, Clement A, Jacquot J, Tabary O
    Biochem. Biophys. Res. Commun., 2007-04-02;357(2):402-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  485. LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes.
    Authors: Kang YM, Kim SY, Kang JH
    Arthritis Rheum., 2007-04-01;56(4):1106-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  486. Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation.
    Authors: Coupel S, Moreau A, Hamidou M, Horejsi V, Soulillou JP, Charreau B
    Blood, 2007-04-01;109(7):2806-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  487. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression.
    Authors: Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H
    Int. J. Oncol., 2007-04-01;30(4):977-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  488. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers.
    Authors: van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH
    Dig. Dis. Sci., 2007-03-30;52(10):2775-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  489. Regulation of neuronal pituitary adenylate cyclase-activating polypeptide expression during culture of guinea-pig cardiac ganglia.
    Authors: Girard BM, Young BA, Buttolph TR, White SL, Parsons RL
    Neuroscience, 2007-03-23;146(2):584-93.
    Species: Guinea Pig
    Sample Types: Whole Cells
    Applications: Bioassay
  490. P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells.
    Authors: Wilson HL, Varcoe RW, Stokes L, Holland KL, Francis SE, Dower SK, Surprenant A, Crossman DC
    Br. J. Pharmacol., 2007-03-12;151(1):115-27.
    Species: Human
    Sample Types: N/A, Whole Cells
    Applications: Bioassay, Western Blot
  491. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.
    Authors: Brechter AB, Lerner UH
    Arthritis Rheum., 2007-03-01;56(3):910-23.
    Species: Human, Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Bioassay
  492. Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production.
    Authors: Emsley HC, Smith CJ, Gavin CM
    BMC Neurol, 2007-02-28;7(0):5.
    Applications: ELISA (Standard)
  493. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007-02-15;178(4):2229-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  494. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
    Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
    Blood, 2007-02-08;109(10):4272-9.
    Applications: ELISA (Standard)
  495. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
    Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
    Life Sci., 2007-02-03;80(20):1821-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  496. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
    Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
    J. Immunol., 2007-01-15;178(2):1172-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  497. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
    Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2007-01-01;210(1):192-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  498. Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.
    Authors: Pietila TE, Veckman V, Lehtonen A, Lin R, Hiscott J, Julkunen I
    J. Immunol., 2007-01-01;178(1):253-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  499. Preterm labor is induced by intraamniotic infusions of interleukin-1beta and tumor necrosis factor-alpha but not by interleukin-6 or interleukin-8 in a nonhuman primate model.
    Authors: Sadowsky DW, Adams KM, Gravett MG, Witkin SS, Novy MJ
    Am. J. Obstet. Gynecol., 2006-12-01;195(6):1578-89.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: In Vivo
    Applications: In Vivo
  500. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006-12-01;177(11):7665-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  501. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
    Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
    Glia, 2006-11-01;54(6):619-29.
    Species: Human
    Sample Types: N/A, Whole Cells
    Applications: Bioassay, ELISA (Standard)
  502. Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures.
    Authors: Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole AR, FitzGerald O, Bresnihan B, Veale DJ
    Arthritis Rheum., 2006-10-01;54(10):3152-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  503. Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
    Authors: Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
    J. Endocrinol., 2006-10-01;191(1):65-81.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Bioassay
  504. Changes in periodontal and rheumatological conditions after 2 years in patients with juvenile idiopathic arthritis.
    Authors: Miranda LA, Braga F, Fischer RG, Sztajnbok FR, Figueredo CM, Gustafsson A
    J. Periodontol., 2006-10-01;77(10):1695-700.
    Applications: ELISA (Standard)
  505. Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets.
    Authors: Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY
    Diabetes, 2006-10-01;55(10):2713-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  506. Kinin receptor expression during Staphylococcus aureus infection.
    Authors: Bengtson SH, Phagoo SB, Norrby-Teglund A, Pahlman L, Morgelin M, Zuraw BL, Leeb-Lundberg LM, Herwald H
    Blood, 2006-05-30;108(6):2055-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  507. A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression.
    Authors: Macagno A, Molteni M, Rinaldi A
    J. Exp. Med., 2006-05-22;203(6):1481-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  508. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis.
    Authors: Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2006-05-01;36(5):1309-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  509. The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.
    Authors: Magne D, Palmer G, Barton JL, Mezin F, Talabot-Ayer D, Bas S, Duffy T, Noger M, Guerne PA, Nicklin MJ, Gabay C
    Arthritis Res. Ther., 2006-04-28;8(3):R80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  510. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
    Authors: Nguyen AN, Stebbins EG, Henson M, O&amp;apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS
    Exp. Cell Res., 2006-04-04;312(10):1909-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  511. Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli.
    Authors: Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC
    Am. J. Respir. Cell Mol. Biol., 2006-03-16;35(2):165-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  512. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006-03-15;176(6):3742-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  513. Th2 cytokine response in Major Depressive Disorder patients before treatment.
    Authors: Kiryushko D, Pavon L, Novitskaya V, Sandoval-Lopez G, Soroka V, Eugenia Hernandez M, Klingelhofer J, Loria F, Lukanidin E, Estrada I, Berezin V, Perez M, Bock E, Moreno J, Avila U, Leff P, Anton B, Heinze G
    J. Neuroimmunol., 2006-02-02;172(1):156-65.
    Applications: ELISA (Standard)
  514. Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells.
    Authors: Edwards MR, Johnson MW, Johnston SL
    Am. J. Respir. Cell Mol. Biol., 2006-01-19;34(5):616-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  515. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2005-12-05;38(4):497-508.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  516. Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes.
    Authors: Mortara L, Ploquin MJ, Faye A, Scott-Algara D, Vaslin B, Butor C, Hosmalin A, Barre-Sinoussi F, Diop OM, Muller-Trutwin MC
    J. Immunol. Methods, 2005-11-21;308(1):138-55.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Whole Cells
  517. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
    Authors: Vergne-Salle</LastName><F P</Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
    Cytokine, 2005-09-07;31(5):335-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  518. Pre-interleukin-1alpha expression reduces cell growth and increases interleukin-6 production in SaOS-2 osteosarcoma cells: Differential inhibitory effect of interleukin-1 receptor antagonist (icIL-1Ra1).
    Authors: Palmer G, Trolliet S, Talabot-Ayer D, Mezin F, Magne D, Gabay C
    Cytokine, 2005-07-21;31(2):153-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  519. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
    Authors: Ameredes BT, Calhoun WJ
    J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  520. Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.
    Authors: Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B
    Arthritis Rheum., 2005-05-01;52(5):1504-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  521. Interleukin-1beta induces CREB-binding protein (CBP) mRNA in brain and the sequencing of rat CBP.
    Authors: Tang C, Sula MJ, Bohnet S, Rehman A, Taishi P, Krueger JM
    Brain Res. Mol. Brain Res., 2005-04-25;137(1):213-22.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  522. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta.
    Authors: Nagineni CN, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2005-04-01;203(1):35-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  523. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K.
    Authors: Mandelin J, Li TF, Hukkanen M, Liljestrom M, Salo J, Santavirta S, Konttinen YT
    J. Rheumatol., 2005-04-01;32(4):713-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  524. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.
    Authors: Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM
    Arthritis Rheum., 2005-03-01;52(3):770-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  525. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1.
    Authors: Yamamoto H, Nagata M, Sakamoto Y
    Ann. Allergy Asthma Immunol., 2005-02-01;94(2):292-300.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  526. TNFalpha increases the inflammatory response to vascular balloon injury without accelerating neointimal formation.
    Authors: Miller AM, McPhaden AR, Preston A, Wadsworth RM, Wainwright CL
    Atherosclerosis, 2004-12-23;179(1):51-9.
    Species: Rabbit
    Sample Types: Whole Tissue
    Applications: Bioassay
  527. trans fatty acids and systemic inflammation in heart failure.
    Authors: Mozaffarian D, Rimm EB, King IB, Lawler RL, McDonald GB, Levy WC
    Am. J. Clin. Nutr., 2004-12-01;80(6):1521-5.
    Applications: ELISA (Standard)
  528. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004-11-22;200(11):1419-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  529. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs.
    Authors: Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, Bougras G, Muller WA, Moretta L, Munz C
    Proc. Natl. Acad. Sci. U.S.A., 2004-11-09;101(47):16606-11.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  530. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure.
    Authors: Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A
    J. Immunol., 2004-11-01;173(9):5810-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  531. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
    Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
    J. Immunol., 2004-09-01;173(5):3482-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  532. Expression of Fas but not Fas ligand on fetal pig beta cells.
    Authors: Bai L, Maedler K, Donath M, Tuch BE
    Xenotransplantation, 2004-09-01;11(5):426-35.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  533. Interleukin-1 inhibits voltage-dependent P/Q-type Ca2+ channel associated with the inhibition of the rise of intracellular free Ca2+ concentration and catecholamine release in adrenal chromaffin cells.
    Authors: Morita K, Miyasako T, Kitayama S, Dohi T
    Biochim. Biophys. Acta, 2004-08-04;1673(3):160-9.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  534. Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
    Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N
    J. Virol., 2004-06-01;78(12):6151-61.
    Species: Primate - Pan troglodytes (Chimpanzee)
    Sample Types: Whole Cells
    Applications: Bioassay
  535. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
    Authors: Phillips TM
    Electrophoresis, 2004-06-01;25(10):1652-9.
  536. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
    Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
    Biochem. J., 2004-06-01;380(0):425-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  537. CD14 is an acute-phase protein.
    Authors: Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C
    J. Immunol., 2004-04-01;172(7):4470-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  538. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004-03-25;104(2):314-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  539. Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads.
    Authors: Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI
    Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  540. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
    Authors: Copeland S, Siddiqui J, Remick D
    J. Immunol. Methods, 2004-01-01;284(1):99-106.
    Applications: ELISA (Standard)
  541. Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes.
    Authors: Liu R, Liote F, Rose DM, Merz D, Terkeltaub R
    Arthritis Rheum., 2004-01-01;50(1):247-58.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  542. Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition.
    Authors: Studer RK, Bergman R, Stubbs T, Decker K
    Arthritis Res. Ther., 2003-11-07;6(1):R56-R64.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  543. ING-1(heMAb), a monoclonal antibody to epithelial cell adhesion molecule, inhibits tumor metastases in a murine cancer model.
    Authors: Ruan HH, Scott KR, Bautista E, Ammons WS
    Neoplasia, 2003-11-01;5(6):489-94.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  544. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
    Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
    J. Clin. Invest., 2003-08-01;112(4):598-607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  545. Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
    Authors: Park JS, 107290, Kim YS, Jee YK, Myong NH, Lee KY
    Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 2003-05-01;57(5):463-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  546. Alteration of locus coeruleus neuronal activity by interleukin-1 and the involvement of endogenous corticotropin-releasing hormone.
    Authors: Borsody MK, Weiss JM
    Neuroimmunomodulation, 2003-01-01;10(2):101-21.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  547. The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action.
    Authors: Smith DE, Hanna R, Della Friend, Moore H, Chen H, Farese AM, MacVittie TJ, Virca GD, Sims JE
    Immunity, 2003-01-01;18(1):87-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  548. Tumour necrosis factor-alpha- and interleukin-1beta-stimulated cell proliferation through activation of mitogen-activated protein kinase in canine tracheal smooth muscle cells.
    Authors: Yang CM, Luo SF, Wang CC, Chiu CT, Chien CS, Lin CC, Hsiao LD
    Br. J. Pharmacol., 2000-06-01;130(4):891-9.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  549. Gingival crevicular fluid from patients with periodontitis contains bone resorbing activity.
    Authors: Lerner UH, Modeer T, Krekmanova L, Claesson R, Rasmussen L
    Eur. J. Oral Sci., 1998-06-01;106(3):778-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Does IL-1 beta induce NO in smooth muscle?

    • Yes it does, based on the literature.

  2. Does Recombinant Human IL-1 beta/IL-1F2 Protein (catalog 201-LB) contain the propeptide?

    • The sequence of this protein is Ala117-Ser269 from Accession # NP_000567. This is the mature form and does not include the propeptide.

  3. Can I reconstitute Recombinant Human IL-1 beta/IL-1F2 Protein (catalog # 201-LB) at a different concentration than recommended?

    • We cannot guarantee the performance if the protein is reconstituted at a different concentration than recommended in the product datasheet. Please contact Technical Service if you have any questions or concerns about reconstitution.

View all Proteins and Enzyme FAQs
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Reviews for Recombinant Human IL-1 beta/IL-1F2 Protein

Average Rating: 4.7 (Based on 18 Reviews)

5 Star
63.16%
4 Star
31.58%
3 Star
0%
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Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 05/21/2021
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 11/09/2020
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 05/23/2020
Application: CellProlif

Recombinant Human IL-1 beta/IL-1F2 Protein
By Shengyun Ma on 05/23/2020
Application: CellProlif

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 01/10/2020
Application: Immunoassay Standard

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 01/07/2020
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By deng guo on 03/22/2019
Application: Enzymatic activity in vitro
Reason for Rating: Works as expected.

We used recombinant human IL-1 beta with different concentration (0.5 to 5 ng/ml) to stimulate mouse aorta ring (C57/B6) for 24 hrs, then ROS activity was measured with DHE. It showed dose dependent activation of ROS in smooth muscle cells.


Recombinant Human IL-1 beta/IL-1F2 Protein
By Jennifer Taggart on 11/07/2018
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 11/05/2018
Application: Media additive for protein or antibody production

Recombinant Human IL-1 beta/IL-1F2 Protein
By shelley Cutrone on 11/05/2018
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 11/05/2018
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 08/06/2018
Application: In vitro bioactivity in cell culture

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 03/02/2018
Application: Binding assay/Protein-protein interaction

Recombinant Human IL-1 beta/IL-1F2 Protein
By Jim Hsiao on 12/15/2017
Application: As an inflammation activator.
Reason for Rating: Primary human airway epithelial cells were treated with IL-1b (1ng/ml) for 24 hours. The supernatant was collected and analyzed for IL-8.

Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 06/07/2017
Application: In vitro bioactivity in cell culture
Reason for Rating: Worked well

qPCR


Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 04/24/2017

Reason for Rating: The ELISA protocol is easy to follow and to use. It does not require to much time to perform. My samples did not express it and I confirmed it twice.

Human Serum used in a dilution of 1/5.


Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 12/15/2016
Application: Stem/Immune cell maintenance or differentiation

Recombination Human IL-1 beta was used to insult iPSc derived Astrocyte to induce cytokine secretion.


Recombinant Human IL-1 beta/IL-1F2 Protein
By Anonymous on 07/29/2016
Application: In vitro bioactivity in cell culture

HUVEC cells were treated with a variety of pro-inflammatory stimuli. IL-1B treatment (right-hand column of each graph) resulted in increased IL-6 and ICAM1 expression, decreased eNOS expression, and massive self-upregulation.