Recombinant Human BDNF Protein

Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
Authors: Z Álvarez, JA Ortega, K Sato, IR Sasselli, AN Kolberg-Ed, R Qiu, KA Marshall, TP Nguyen, CS Smith, KA Quinlan, V Papakis, Z Syrgiannis, NA Sather, C Musumeci, E Engel, SI Stupp, E Kiskinis
Cell Stem Cell, 2023-01-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons
Authors: O Pietiläine, A Trehan, D Meyer, J Mitchell, M Tegtmeyer, V Valakh, H Gebre, T Chen, E Vartiainen, SL Farhi, K Eggan, SA McCarroll, R Nehme
Cell Reports, 2023-01-12;42(1):111988.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
Authors: Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer
Cell Stem Cell, 2023;30(3):264-282.e9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease
Authors: JR Herdy, L Traxler, RK Agarwal, L Karbacher, JCM Schlachetz, L Boehnke, D Zangwill, D Galasko, CK Glass, J Mertens, FH Gage
Cell Stem Cell, 2022-12-01;29(12):1637-1652.e6.
Species: Human
Sample Types: Transduced Whole Cells
Applications: Bioassay

A reference human induced pluripotent stem cell line for large-scale collaborative studies
Authors: CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendra, L Peng, H Oguro, J Kanaujiya, J Zou, D Sebesta, G Pratt, E Cross, J Blockwick, P Buxton, L Kinner-Bib, C Medura, C Tompkins, S Hughes, M Santiana, F Faghri, MA Nalls, D Vitale, S Ballard, YA Qi, DM Ramos, KM Anderson, J Stadler, P Narayan, J Papademetr, L Reilly, MP Nelson, S Aggarwal, LU Rosen, P Kirwan, V Pisupati, SL Coon, SW Scholz, T Priebe, M Öttl, J Dong, M Meijer, LJM Janssen, VS Lourenco, R van der Ka, D Crusius, D Paquet, AC Raulin, G Bu, A Held, BJ Wainger, RMC Gabriele, JM Casey, S Wray, D Abu-Bonsra, CL Parish, MS Beccari, DW Cleveland, E Li, IVL Rose, M Kampmann, C Calatayud, P Verstreken, L Heinrich, MY Chen, B Schüle, D Dou, ELF Holzbaur, MC Zanellati, R Basundra, M Deshmukh, S Cohen, R Khanna, M Raman, ZS Nevin, M Matia, J Van Lent, V Timmerman, BR Conklin, K Johnson Ch, K Zhang, S Funes, DA Bosco, L Erlebach, M Welzer, D Kronenberg, G Lyu, E Arenas, E Coccia, L Sarrafha, T Ahfeldt, JC Marioni, WC Skarnes, MR Cookson, ME Ward, FT Merkle
Cell Stem Cell, 2022-12-01;29(12):1685-1702.e22.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models
Authors: HF Wu, W Yu, K Saito-Diaz, CW Huang, J Carey, F Lefcort, GW Hart, HX Liu, N Zeltner
Nature Communications, 2022-11-17;13(1):7032.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2
Authors: G Kim, L Nakayama, JA Blum, T Akiyama, S Boeynaems, M Chakrabort, J Couthouis, E Tassoni-Ts, CM Rodriguez, MC Bassik, AD Gitler
Cell Reports, 2022-10-25;41(4):111508.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling gene � environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
Authors: C Seah, MS Breen, T Rusielewic, HN Bader, C Xu, CJ Hunter, B McCarthy, PJM Deans, M Chattopadh, J Goldberg, F Desarnaud, I Makotkine, JD Flory, LM Bierer, M Staniskyte, NYSCF Glob, SA Noggle, LM Huckins, D Paull, KJ Brennand, R Yehuda
Nature Neuroscience, 2022-10-20;25(11):1434-1445.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G2019S LRRK2 Mutation Enhances MPP+-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic Neurons
Authors: Y Chen, Q Yin, XY Cheng, JR Zhang, H Jin, K Li, CJ Mao, F Wang, HZ Bei, CF Liu
Frontiers in Neuroscience, 2022-07-06;16(0):947927.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1
Authors: MK Eltahir, M Nakamori, S Hattori, T Kimura, H Mochizuki, S Nagano
PLoS ONE, 2022-07-01;17(7):e0269683.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Neurons Form Axon-Mediated Functional Connections with Human Cardiomyocytes in Compartmentalized Microfluidic Chip
Authors: M Häkli, S Jäntti, T Joki, L Sukki, K Tornberg, K Aalto-Setä, P Kallio, M Pekkanen-M, S Narkilahti
International Journal of Molecular Sciences, 2022-03-15;23(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells
Authors: MA Hossain, M Hasegawa-O, Y Manome, M Igarashi, C Wu, K Suzuki, J Igarashi, T Iwamoto, HJ Okano, Y Eto
Oncogene, 2022-02-21;31(0):100852.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells
Authors: N Moriarty, CW Gantner, CPJ Hunt, CM Ermine, S Frausin, S Viventi, DA Ovchinniko, D Kirik, CL Parish, LH Thompson
Cell Stem Cell, 2022-02-17;29(3):434-448.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds
Authors: MC Bufalo, MES Almeida, JR Jensen, C DeOcesano-, F Lichtenste, G Picolo, AM Chudzinski, SC Sampaio, Y Cury, VO Zambelli
Cells, 2022-01-12;11(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T alpha-synuclein levels and aggregation
Authors: C Vajhøj, B Schmid, A Alik, R Melki, K Fog, B Holst, TC Stummann
PLoS ONE, 2021-12-21;16(12):e0261536.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optimised techniques for high-throughput screening of differentiated SH-SY5Y cells and application for neurite outgrowth assays
Authors: A Dravid, B Raos, D Svirskis, SJ O'Carroll
Scientific Reports, 2021-12-14;11(1):23935.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons
Authors: AM Earley, LF Burbulla, D Krainc, R Awatramani
Scientific Reports, 2021-11-15;11(1):22257.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Phoenix auditory neurons as 3R cell model for high throughput screening of neurogenic compounds
Authors: F Rousset, D Schmidbaue, S Fink, Y Adel, B Obexer, M Müller, R Glueckert, H Löwenheim, P Senn
Hearing research, 2021-11-14;414(0):108391.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
Authors: P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, M Nordenskjö, P Micke, D Maltseva, AG Tonevitsky, V Millischer, J Carlos Vil, S Kadekar, M Gaetani, K Altynbekov, A Kel, PO Berggren, O Simonson, KH Grinnemo, R Holmdahl, S Rodin, RA Zubarev
Nature Communications, 2021-11-12;12(1):6558.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks
Authors: A Gonzalez-R, E Waloschkov, A Mikroulis, Z Kokaia, J Bengzon, M Ledri, M Andersson, M Kokaia
Scientific Reports, 2021-11-11;11(1):22050.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells
Authors: GP Sharma, AC Frei, J Narayanan, T Gasperetti, D Veley, A Amjad, K Albano, BL Fish, HA Himburg
PLoS ONE, 2021-10-25;16(10):e0259042.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation
Authors: Y Sonobe, J Aburas, G Krishnan, AC Fleming, G Ghadge, P Islam, EC Warren, Y Gu, MW Kankel, AEX Brown, E Kiskinis, TF Gendron, FB Gao, RP Roos, P Kratsios
Nature Communications, 2021-10-15;12(1):6025.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched
Authors: X Reed, MM Cobb, G Skinbinski, D Roosen, A Kaganovich, J Ding, S Finkbeiner, MR Cookson
Stem Cell Research, 2021-10-03;56(0):102558.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Neuroligin-1 mediates presynaptic maturation through brain-derived neurotrophic factor signaling
Authors: A Petkova-Tu, N Gödecke, J Viotti, M Korte, T Dresbach
Bmc Biology, 2021-09-27;19(1):215.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A microfluidic approach to rescue ALS motor neuron degeneration using rapamycin
Authors: P Chennampal, A Sayed-Zahi, P Soundarara, J Sharp, GA Cox, SD Collins, RL Smith
Scientific Reports, 2021-09-13;11(1):18168.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts
Authors: J Sun, DY Shin, M Eiseman, AR Yallowitz, N Li, S Lalani, Z Li, M Cung, S Bok, S Debnath, SJ Marquez, TE White, AG Khan, IC Lorenz, JH Shim, FS Lee, R Xu, MB Greenblatt
Nature Communications, 2021-07-29;12(1):4611.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human stem cells harboring a suicide gene improve the�safety and standardisation of neural transplants in Parkinsonian rats
Authors: IR de Luzy, KCL Law, N Moriarty, CPJ Hunt, JC Durnall, LH Thompson, A Nagy, CL Parish
Nature Communications, 2021-05-27;12(1):3275.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids
Authors: ZT Olmsted, JL Paluh
Nature Communications, 2021-05-21;12(1):3020.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

VEGF Mediates Retinal M�ller Cell Viability and Neuroprotection through BDNF in Diabetes
Authors: YZ Le, B Xu, AJ Chucair-El, H Zhang, M Zhu
Biomolecules, 2021-05-10;11(5):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3
Authors: V Padmanabha, H Liu, G Ciceri, J Jungverdor, G Frishman, J Tchieu, GY Cederquist, I Rothenaign, K Schorpp, L Klepper, RM Walsh, TW Kim, D Cornacchia, A Ruepp, J Mayer, K Hadian, D Frishman, L Studer, M Vincendeau
Cell Stem Cell, 2021-05-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients
Authors: J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetz, L Böhnke, DA Reid, H Lee, D Zangwill, DP Fernandes, RK Agarwal, R Lucciola, L Zhou-Yang, L Karbacher, F Edenhofer, S Stern, S Horvath, ACM Paquola, CK Glass, SH Yuan, M Ku, A Szücs, LSB Goldstein, D Galasko, FH Gage
Cell Stem Cell, 2021-04-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury
Authors: CV Latchouman, MI Betancur, GA Simchick, MK Sun, R Forghani, CE Lenear, A Ahmed, R Mohankumar, N Balaji, HD Mason, SA Archer-Har, P Azadi, PV Holmes, Q Zhao, RV Bellamkond, L Karumbaiah
Science Advances, 2021-03-05;7(10):.
Species: Rat
Sample Types: In Vivo
Applications: Bioassay

Brain-Derived Neurotrophic Factor Expression and Signaling in Different Perivascular Adipose Tissue Depots of Patients With Coronary Artery Disease
Authors: S Zierold, K Buschmann, S Gachkar, ML Bochenek, D Velmeden, L Hobohm, CF Vahl, K Schäfer
Journal of the American Heart Association, 2021-03-05;10(6):e018322.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect
Authors: GLM Arruda, H Vigerelli, MC Bufalo, GB Longato, RV Veloso, VO Zambelli, G Picolo, Y Cury, AC Morandini, AC Marques, JM Sciani
BioMed Research International, 2021-03-04;2021(0):8855248.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment
Authors: X Dong, L Yang, K Liu, X Ji, C Tang, W Li, L Ma, Y Mei, T Peng, B Feng, Z Wu, Q Tang, Y Gao, K Yan, W Zhou, M Xiong
Cell Reports, 2021-03-02;34(9):108802.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation
Authors: E Solomon, K Davis-Ande, B Hovde, S Micheva-Vi, JF Harris, S Twary, R Iyer
BMC molecular and cell biology, 2021-02-18;22(1):13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use
Authors: TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel, ND Socci, SJ Choi, S Zabierowsk, BN Dubose, EJ Hill, EV Mosharov, S Irion, MJ Tomishima, V Tabar, L Studer
Cell Stem Cell, 2021-02-04;28(2):343-355.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay
Authors: T Kurosaki, N Imamachi, C Pröschel, S Mitsutomi, R Nagao, N Akimitsu, LE Maquat
Nature Cell Biology, 2021-01-08;23(1):40-48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel method to produce a layered 3D scaffold for human pluripotent stem cell-derived neuronal cells
Authors: L Honkamäki, T Joki, NA Grigoryev, K Levon, L Ylä-Outine, S Narkilahti
Journal of neuroscience methods, 2020-12-17;350(0):109043.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis
Authors: D Jutzi, S Campagne, R Schmidt, S Reber, J Mechtershe, F Gypas, C Schweingru, M Colombo, C von Schroe, FE Loughlin, A Devoy, E Hedlund, M Zavolan, FH Allain, MD Ruepp
Nature Communications, 2020-12-11;11(1):6341.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors
Authors: S Lito, A Sidibe, S Ilmjarv, P Burda, M Baumgartne, B Wehrle-Hal, KH Krause, A Marteyn
Cells, 2020-12-03;9(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3
Authors: N Ramesh, EL Daley, AM Gleixner, JR Mann, S Kour, D Mawrie, EN Anderson, J Kofler, CJ Donnelly, E Kiskinis, UB Pandey
Acta Neuropathol Commun, 2020-10-31;8(1):177.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
Authors: KC Allan, LR Hu, MA Scavuzzo, AR Morton, AS Gevorgyan, EF Cohn, BLL Clayton, IR Bederman, S Hung, CF Bartels, M Madhavan, PJ Tesar
Cell Stem Cell, 2020-10-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis
Authors: JW Kim, X Yin, A Jhaldiyal, MR Khan, I Martin, Z Xie, T Perez-Rose, M Kumar, L Abalde-Atr, J Xu, L Chen, SM Eacker, DJ Surmeier, NT Ingolia, TM Dawson, VL Dawson
Cell Stem Cell, 2020-08-25;27(4):633-645.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Age-Dependency of Neurite Outgrowth in Postnatal Mouse Cochlear Spiral Ganglion Explants
Authors: C Frick, S Fink, D Schmidbaue, F Rousset, H Eickhoff, A Tropitzsch, B Kramer, P Senn, R Glueckert, H Rask-Ander, KH Wiesmüller, H Löwenheim, M Müller
Brain Sci, 2020-08-21;10(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modulation of Human Adipose Stem Cells' Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro
Authors: KM Prautsch, A Schmidt, V Paradiso, DJ Schaefer, R Guzman, DF Kalbermatt, S Madduri
Cells, 2020-08-21;9(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates
Authors: K Hirata, T Nambara, K Kawatani, N Nawa, H Yoshimatsu, H Kusakabe, K Banno, K Nishimura, M Ohtaka, M Nakanishi, H Taniguchi, H Arahori, K Wada, K Ozono, Y Kitabatake
Sci Rep, 2020-08-20;10(1):14047.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Consecutive Treatment with Brain-Derived Neurotrophic Factor and Electrical Stimulation Has a Protective Effect on Primary Auditory Neurons
Authors: V Scheper, I Seidel-Eff, T Lenarz, T Stöver, G Paasche
Brain sciences, 2020-08-15;10(8):.
Species: Guinea Pig
Sample Types: In Vivo
Applications: Bioassay

Developmental changes in the accessible chromatin, transcriptome and Ascl1-binding correlate with the loss in M�ller Glial regenerative potential
Authors: LS VandenBosc, SG Wohl, MS Wilken, M Hooper, C Finkbeiner, K Cox, L Chipman, TA Reh
Sci Rep, 2020-08-12;10(1):13615.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells
Authors: CA Tristan, P Ormanoglu, J Slamecka, C Malley, PH Chu, VM Jovanovic, Y Gedik, C Bonney, E Barnaeva, J Braisted, SK Mallanna, D Dorjsuren, MJ Iannotti, TC Voss, S Michael, A Simeonov, I Singeç
bioRxiv, 2020-08-03;0(0):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells
Authors: M Chen, M Maimaitili, M Habekost, KP Gill, N Mermet-Jor, S Nabavi, F Febbraro, M Denham
Stem Cell Res, 2020-08-03;48(0):101945.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction
Authors: N Michel, P Narayanan, O Shomroni, M Schmidt
Cell Rep, 2020-07-21;32(3):107912.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020-06-19;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns
Authors: S Das Sharma, R Pal, BK Reddy, BT Selvaraj, N Raj, KK Samaga, DJ Srinivasan, L Ornelas, D Sareen, MR Livesey, GJ Bassell, CN Svendsen, PC Kind, S Chandran, S Chattarji, DJA Wyllie
Mol Autism, 2020-06-19;11(1):52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities
Authors: T Sonoyama, LKJ Stadler, M Zhu, JM Keogh, E Henning, F Hisama, P Kirwan, M Jura, BK Blaszczyk, DC DeWitt, B Brouwers, M Hyvönen, I Barroso, FT Merkle, SM Appleyard, GA Wayman, IS Farooqi
Sci Rep, 2020-06-03;10(1):9028.
Species: Transgenic Rat
Sample Types: Whole Cells
Applications: Bioassay

Neurons from human mesenchymal stem cells display both spontaneous and stimuli responsive activity
Authors: N Karaka?, S Bay, N Türkel, N Öztunç, M Öncül, H Bilgen, K Shah, F ?ahin, G Öztürk
PLoS ONE, 2020-05-14;15(5):e0228510.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
Cell Rep, 2020-05-05;31(5):107599.
Species: Mouse
Sample Types:
Applications: Cell Culture

Fingolimod Modulates Dendritic Architecture in a BDNF-Dependent Manner
Authors: A Patnaik, E Spiombi, A Frasca, N Landsberge, M Zagrebelsk, M Korte
Int J Mol Sci, 2020-04-27;21(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Capsosiphon fulvescens Glycoproteins Enhance Probiotics-Induced Cognitive Improvement in Aged Rats
Authors: JH Oh, TJ Nam, YH Choi
Nutrients, 2020-03-20;12(3):.
Species: Rat
Sample Types:
Applications: In Vivo

Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping
Authors: P Gee, MSY Lung, Y Okuzaki, N Sasakawa, T Iguchi, Y Makita, H Hozumi, Y Miura, LF Yang, M Iwasaki, XH Wang, MA Waller, N Shirai, YO Abe, Y Fujita, K Watanabe, A Kagita, KA Iwabuchi, M Yasuda, H Xu, T Noda, J Komano, H Sakurai, N Inukai, A Hotta
Nat Commun, 2020-03-13;11(1):1334.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes
Authors: K Matsumura, K Seiriki, S Okada, M Nagase, S Ayabe, I Yamada, T Furuse, H Shibuya, Y Yasuda, H Yamamori, M Fujimoto, K Nagayasu, K Yamamoto, K Kitagawa, H Miura, N Gotoda-Nis, H Igarashi, M Hayashida, M Baba, M Kondo, S Hasebe, K Ueshima, A Kasai, Y Ago, A Hayata-Tak, N Shintani, T Iguchi, M Sato, S Yamaguchi, M Tamura, S Wakana, A Yoshiki, AM Watabe, H Okano, K Takuma, R Hashimoto, H Hashimoto, T Nakazawa
Nat Commun, 2020-02-26;11(1):859.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optogenetic control of mRNA localization and translation in live cells
Authors: NY Kim, S Lee, J Yu, N Kim, SS Won, H Park, WD Heo
Nat. Cell Biol., 2020-02-17;0(0):.
Species: Transgenic Rat
Sample Types: Whole Cells
Applications: Bioassay

Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease
Authors: CW Gantner, IR de Luzy, JA Kauhausen, N Moriarty, JC Niclis, CR Bye, V Penna, CPJ Hunt, CM Ermine, CW Pouton, D Kirik, LH Thompson, CL Parish
Cell Stem Cell, 2020-02-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FICD activity and AMPylation remodelling modulate human neurogenesis
Authors: P Kielkowski, IY Buchsbaum, VC Kirsch, NC Bach, M Drukker, S Cappello, SA Sieber
Nat Commun, 2020-01-24;11(1):517.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
Authors: EE Burke, JG Chenoweth, JH Shin, L Collado-To, SK Kim, N Micali, Y Wang, C Colantuoni, RE Straub, DJ Hoeppner, HY Chen, A Sellers, K Shibbani, GR Hamersky, M Diaz Busta, BN Phan, WS Ulrich, C Valencia, A Jaishankar, AJ Price, A Rajpurohit, SA Semick, RW Bürli, JC Barrow, DJ Hiler, SC Page, K Martinowic, TM Hyde, JE Kleinman, KF Berman, JA Apud, AJ Cross, NJ Brandon, DR Weinberger, BJ Maher, RDG McKay, AE Jaffe
Nat Commun, 2020-01-23;11(1):462.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells
Authors: AR Nickolls, MM Lee, DF Espinoza, M Szczot, RM Lam, Q Wang, J Beers, J Zou, MQ Nguyen, HJ Solinski, AA AlJanahi, KR Johnson, ME Ward, AT Chesler, CG Bönnemann
Cell Rep, 2020-01-21;30(3):932-946.e7.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis
Authors: H Ding, J Chen, M Su, Z Lin, H Zhan, F Yang, W Li, J Xie, Y Huang, X Liu, B Liu, X Zhou
J Neuroinflammation, 2020-01-13;17(1):19.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain
Authors: P Bhattarai, MI Cosacak, V Mashkaryan, S Demir, SD Popova, N Govindaraj, K Brandt, Y Zhang, W Chang, K Ampatzis, C Kizil
PLoS Biol., 2020-01-06;18(1):e3000585.
Species: Mouse, Zebrafish
Sample Types: In Vivo
Applications: In Vivo

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Roles of Collagen XXV and Its Putative Receptors PTPsigma/delta in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder
Authors: H Munezane, H Oizumi, T Wakabayash, S Nishio, T Hirasawa, T Sato, A Harada, T Yoshida, T Eguchi, Y Yamanashi, T Hashimoto, T Iwatsubo
Cell Rep, 2019-12-24;29(13):4362-4376.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
Authors: M Chumarina, K Russ, C Azevedo, A Heuer, M Pihl, A Collin, EÅ Frostner, E Elmer, P Hyttel, G Cappellett, M Zini, S Goldwurm, L Roybon
Acta Neuropathol Commun, 2019-12-16;7(1):208.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a neurogenic niche
Authors: Y Zheng, X Xue, AM Resto-Iriz, Z Li, Y Shao, Y Zheng, G Zhao, J Fu
Sci Adv, 2019-12-11;5(12):eaax5933.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells
Authors: AL Gill, MZ Wang, B Levine, A Premasiri, FG Vieira
Int J Mol Sci, 2019-12-11;20(24):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors
Authors: S Mahajani, A Raina, C Fokken, S Kügler, M Bähr
Cell Death Dis, 2019-11-27;10(12):898.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures
Authors: T Hyvärinen, A Hyysalo, FE Kapucu, L Aarnos, A Vinogradov, SJ Eglen, L Ylä-Outine, S Narkilahti
Sci Rep, 2019-11-20;9(1):17125.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches
Authors: A Brosig, J Fuchs, F Ipek, C Kroon, S Schrötter, M Vadhvani, A Polyzou, J Ledderose, M van Diepen, HG Holzhütter, T Trimbuch, N Gimber, J Schmoranze, I Lieberam, C Rosenmund, C Spahn, P Scheerer, M Szczepek, G Leondariti, BJ Eickholt
Cell Rep, 2019-11-12;29(7):2028-2040.e8.
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture

Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons
Authors: HM Larsen, SK Hansen, JD Mikkelsen, P Hyttel, TC Stummann
Stem Cell Res, 2019-10-31;41(0):101642.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation
Authors: D Leitner, M Ramamoorth, M Dejosez, TP Zwaka
Stem Cell Res, 2019-10-24;41(0):101617.
Species: Human, Mouse
Sample Types: In Vitro, Whole Cells
Applications: Cell Culture, In vitro

Isolation of LMX1a ventral midbrain progenitors improves the safety and predictability of human pluripotent stem cell-derived neural transplants in Parkinsonian Disease
Authors: IR de Luzy, JC Niclis, CW Gantner, JA Kauhausen, CPJ Hunt, C Ermine, CW Pouton, LH Thompson, CL Parish
J. Neurosci., 2019-10-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V2a interneuron differentiation from mouse and human pluripotent stem cells
Authors: JC Butts, N Iyer, N White, R Thompson, S Sakiyama-E, TC McDevitt
Nat Protoc, 2019-10-18;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Relevance of Neurotrophin Receptors CD271 and TrkC for Prognosis, Migration, and Proliferation in Head and Neck Squamous Cell Carcinoma
Authors: Y Foerster, T Stöver, J Wagenblast, M Diensthube, S Balster, J Gabrielpil, H Petzold, C Geissler
Cells, 2019-09-28;8(10):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates
Authors: R Aron Badin, A Bugi, S Williams, M Vadori, M Michael, C Jan, A Nassi, S Lecourtois, A Blancher, E Cozzi, P Hantraye, AL Perrier
Nat Commun, 2019-09-25;10(1):4357.
Species: Primate (Macaca fascicularis)
Sample Types: Whole Cells
Applications: Cell Culture

Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons
Authors: M Riessland, B Kolisnyk, TW Kim, J Cheng, J Ni, JA Pearson, EJ Park, K Dam, D Acehan, LS Ramos-Espi, W Wang, J Zhang, JW Shim, G Ciceri, L Brichta, L Studer, P Greengard
Cell Stem Cell, 2019-09-19;25(4):514-530.e8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

iPSC-derived functional human neuromuscular junctions model the pathophysiology of neuromuscular diseases
Authors: CY Lin, M Yoshida, LT Li, A Ikenaka, S Oshima, K Nakagawa, H Sakurai, E Matsui, T Nakahata, MK Saito
JCI Insight, 2019-09-19;4(18):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
Authors: KN Babos, KE Galloway, K Kisler, M Zitting, Y Li, Y Shi, B Quintino, RH Chow, BV Zlokovic, JK Ichida
Cell Stem Cell, 2019-09-12;25(4):486-500.e9.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain
Authors: LJ Zhou, J Peng, YN Xu, WJ Zeng, J Zhang, X Wei, CL Mai, ZJ Lin, Y Liu, M Murugan, UB Eyo, AD Umpierre, WJ Xin, T Chen, M Li, H Wang, JR Richardson, Z Tan, XG Liu, LJ Wu
Cell Rep, 2019-06-25;27(13):3844-3859.e6.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

Differentiation of Motor Neuron-Like Cells from Tonsil-Derived Mesenchymal Stem Cells and Their Possible Application to Neuromuscular Junction Formation
Authors: S Park, JY Kim, S Myung, N Jung, Y Choi, SC Jung
Int J Mol Sci, 2019-06-01;20(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Microelectrode Array With Transparent ALD TiN Electrodes
Authors: T Ryynänen, A Pelkonen, K Grigoras, OME Ylivaara, T Hyvärinen, J Ahopelto, M Prunnila, S Narkilahti, J Lekkala
Front Neurosci, 2019-03-22;13(0):226.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gadd45b mediates depressive-like role through DNA demethylation
Authors: B Labonté, YH Jeong, E Parise, O Issler, M Fatma, O Engmann, KA Cho, R Neve, EJ Nestler, JW Koo
Sci Rep, 2019-03-15;9(1):4615.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4
Authors: N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup
Sci Rep, 2019-03-14;9(1):4515.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
Authors: J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, YL Tay, A Ziaei, R Zeng, D Low, F Aminkeng, RM Sobota, F Ginhoux, E Petretto, MA Pouladi
Cell Rep, 2019-02-26;26(9):2494-2508.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson's Disease Patients
Authors: M Elkouris, G Kouroupi, A Vourvoukel, N Papagianna, V Kaltezioti, R Matsas, L Stefanis, M Xilouri, PK Politis
Front Cell Neurosci, 2019-02-22;13(0):58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development
Authors: L Wang, AJ De Solis, Y Goffer, KE Birkenbach, SE Engle, R Tanis, JM Levenson, X Li, R Rausch, M Purohit, JY Lee, J Tan, MC De Rosa, CA Doege, HL Aaron, GJ Martins, JC Brüning, D Egli, R Costa, N Berbari, RL Leibel, G Stratigopo
JCI Insight, 2019-02-07;4(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
Authors: R Hamnett, P Crosby, JE Chesham, MH Hastings
Nat Commun, 2019-02-01;10(1):542.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

MAP4K4 Activation Mediates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis
Authors: C Wu, ME Watts, LL Rubin
Cell Rep, 2019-01-29;26(5):1143-1156.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations
Authors: C Iwasawa, N Kuzumaki, Y Suda, R Kagawa, Y Oka, N Hattori, H Okano, M Narita
Mol Brain, 2019-01-18;12(1):5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
Authors: JR Klim, LA Williams, F Limone, I Guerra San, BN Davis-Duse, DA Mordes, A Burberry, MJ Steinbaugh, KK Gamage, R Kirchner, R Moccia, SH Cassel, K Chen, BJ Wainger, CJ Woolf, K Eggan
Nat. Neurosci., 2019-01-14;22(2):167-179.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
Authors: Z Melamed, J López-Erau, MW Baughn, O Zhang, K Drenner, Y Sun, F Freyermuth, MA McMahon, MS Beccari, JW Artates, T Ohkubo, M Rodriguez, N Lin, D Wu, CF Bennett, F Rigo, S Da Cruz, J Ravits, C Lagier-Tou, DW Cleveland
Nat. Neurosci., 2019-01-14;22(2):180-190.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Polybenzyl Glutamate Biocompatible Scaffold Promotes the Efficiency of Retinal Differentiation toward Retinal Ganglion Cell Lineage from Human-Induced Pluripotent Stem Cells
Authors: TC Chen, PY She, DF Chen, JH Lu, CH Yang, DS Huang, PY Chen, CY Lu, KS Cho, HF Chen, WF Su
Int J Mol Sci, 2019-01-05;20(1):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau
Authors: MB Huynh, MO Ouidja, S Chantepie, G Carpentier, A Maïza, G Zhang, J Vilares, R Raisman-Vo, D Papy-Garci
PLoS ONE, 2019-01-04;14(1):e0209573.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Probing the mechanism of inhibition of amyloid-?(1-42)-induced neurotoxicity by the chaperonin GroEL
Authors: MA Wälti, J Steiner, F Meng, HS Chung, JM Louis, R Ghirlando, V Tugarinov, A Nath, GM Clore
Proc. Natl. Acad. Sci. U.S.A., 2018-12-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem�-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke
Authors: K Ravina, DI Briggs, S Kislal, Z Warraich, T Nguyen, RK Lam, TI Zarembinsk, M Shamloo
Int J Mol Sci, 2018-11-28;19(12):.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones
Authors: NV Vysokov, JP Silva, VG Lelianova, J Suckling, J Cassidy, JK Blackburn, N Yankova, MB Djamgoz, SV Kozlov, AG Tonevitsky, YA Ushkaryov
Elife, 2018-11-20;7(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Divergent Prelimbic Cortical Pathways Interact with BDNF to Regulate Cocaine Seeking
Authors: G Giannotti, SM Barry, BM Siemsen, J Peters, JF McGinty
J. Neurosci., 2018-09-05;0(0):.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition
Authors: K Kirino, T Nakahata, T Taguchi, MK Saito
Sci Rep, 2018-08-27;8(1):12865.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent
Authors: K Fujimori, M Ishikawa, A Otomo, N Atsuta, R Nakamura, T Akiyama, S Hadano, M Aoki, H Saya, G Sobue, H Okano
Nat. Med., 2018-08-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients
Authors: S Koyuncu, I Saez, HJ Lee, R Gutierrez-, W Pokrzywa, A Fatima, T Hoppe, D Vilchez
Nat Commun, 2018-07-23;9(1):2886.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model
Authors: N Tsuburaya, K Homma, T Higuchi, A Balia, H Yamakoshi, N Shibata, S Nakamura, H Nakagawa, SI Ikeda, N Umezawa, N Kato, S Yokoshima, M Shibuya, M Shimonishi, H Kojima, T Okabe, T Nagano, I Naguro, K Imamura, H Inoue, T Fujisawa, H Ichijo
Nat Commun, 2018-07-10;9(1):2668.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate
Authors: MZ Ozair, C Kirst, BL van den Be, A Ruzo, T Rito, AH Brivanlou
Cell Stem Cell, 2018-06-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons
Authors: G Collo, L Cavalleri, M Zoli, U Maskos, E Ratti, E Merlo Pich
Front Pharmacol, 2018-06-01;9(0):572.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS
Authors: KL Gibbs, B Kalmar, ER Rhymes, AD Fellows, M Ahmed, P Whiting, CH Davies, L Greensmith, G Schiavo
Cell Death Dis, 2018-05-22;9(6):596.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In�Vitro
Authors: A Sarkar, A Mei, ACM Paquola, S Stern, C Bardy, JR Klug, S Kim, N Neshat, HJ Kim, M Ku, MN Shokhirev, DH Adamowicz, MC Marchetto, R Jappelli, JA Erwin, K Padmanabha, M Shtrahman, X Jin, FH Gage
Cell Stem Cell, 2018-05-03;22(5):684-697.e9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin
Authors: L Galvan, L Francelle, MC Gaillard, L de Longpre, MA Carrillo-d, G Liot, K Cambon, L Stimmer, S Luccantoni, J Flament, J Valette, M de Chaldée, G Auregan, M Guillermie, C Joséphine, F Petit, C Jan, M Jarrige, N Dufour, G Bonvento, S Humbert, F Saudou, P Hantraye, K Merienne, AP Bemelmans, AL Perrier, N Déglon, E Brouillet
Brain, 2018-05-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cerebellar BDNF promotes exploration and seeking for novelty
Authors: D Laricchiut, D Andolina, F Angelucci, F Gelfo, E Berretta, S Puglisi-Al, L Petrosini
Int. J. Neuropsychopharmacol., 2018-05-01;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

DNA topoisomerase II? stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression
Authors: M Zaim, S Isik
Stem Cell Res Ther, 2018-04-25;9(1):114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images
Authors: EM Christians, SJ Yang, DM Ando, A Javaherian, G Skibinski, S Lipnick, E Mount, A O'Neil, K Shah, AK Lee, P Goyal, W Fedus, R Poplin, A Esteva, M Berndl, LL Rubin, P Nelson, S Finkbeiner
Cell, 2018-04-12;173(3):792-803.e19.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Subcellular localisation modulates ubiquitylation and degradation of Ascl1
Authors: S Gillotin, JD Davies, A Philpott
Sci Rep, 2018-03-15;8(1):4625.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology
Authors: MJ Ziller, JA Ortega, KA Quinlan, DP Santos, H Gu, EJ Martin, C Galonska, R Pop, S Maidl, A Di Pardo, M Huang, HY Meltzer, A Gnirke, CJ Heckman, A Meissner, E Kiskinis
Cell Stem Cell, 2018-03-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells
Authors: G Inana, C Murat, W An, X Yao, IR Harris, J Cao
J Transl Med, 2018-03-13;16(1):63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SORCS1 and SORCS3 control energy balance and orexigenic peptide production
Authors: A Subkhangul, AR Malik, G Hermey, O Popp, G Dittmar, T Rathjen, MN Poy, A Stumpf, PS Beed, D Schmitz, T Breiderhof, TE Willnow
EMBO Rep., 2018-02-12;19(4):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer
Authors: DR Gomez, LA Byers, M Nilsson, L Diao, J Wang, L Li, P Tong, M Hofstad, B Saigal, I Wistuba, N Kalhor, S Swisher, Y Fan, WK Hong, M Suraokar, C Behrens, C Moran, JV Heymach
Oncotarget, 2018-01-30;9(18):14268-14284.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chromosomal instability during neurogenesis in Huntington's disease
Authors: A Ruzo, GF Croft, JJ Metzger, S Galgoczi, LJ Gerber, C Pellegrini, H Wang, M Fenner, S Tse, A Marks, C Nchako, AH Brivanlou
Development, 2018-01-29;145(2):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Whole genome microarray analysis of neural progenitor C17.2 cells during differentiation and validation of 30 neural mRNA biomarkers for estimation of developmental neurotoxicity
Authors: K Attoff, A Gliga, J Lundqvist, U Norinder, A Forsby
PLoS ONE, 2017-12-20;12(12):e0190066.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation
Authors: EA Newman, S Chukkapall, D Bashllari, TT Thomas, RA Van Noord, ER Lawlor, MJ Hoenerhoff, AW Opipari, VP Opipari
Cell Death Dis, 2017-12-13;8(12):3208.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of neuroactive agents on axonal growth and pathfinding of retinal ganglion cells generated from human stem cells
Authors: T Yokoi, T Tanaka, E Matsuzaka, F Tamalu, SI Watanabe, S Nishina, N Azuma
Sci Rep, 2017-12-01;7(1):16757.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Altered Differentiation Potential of Gaucher's Disease iPSC Neuronal Progenitors due to Wnt/?-Catenin Downregulation
Authors: O Awad, LM Panicker, RM Deranieh, MP Srikanth, RA Brown, A Voit, T Peesay, TS Park, ET Zambidis, RA Feldman
Stem Cell Reports, 2017-11-30;9(6):1853-1867.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
Authors: KY Tseng, JE Anttila, K Khodosevic, RK Tuominen, M Lindahl, A Domanskyi, M Airavaara
Mol. Ther., 2017-09-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons
Authors: K Burk, JD Murdoch, S Freytag, M Koenig, V Bharat, R Markworth, S Burkhardt, A Fischer, C Dean
Sci Rep, 2017-05-19;7(1):2149.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differentiation of nestin?negative human hair follicle outer root sheath cells into neurons in�vitro
Authors: W Wu, XL Wu, YQ Ji, Z Gao
Mol Med Rep, 2017-05-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Common genetic variation drives molecular heterogeneity in human iPSCs
Authors: H Kilpinen, A Goncalves, A Leha, V Afzal, K Alasoo, S Ashford, S Bala, D Bensaddek, FP Casale, OJ Culley, P Danecek, A Faulconbri, PW Harrison, A Kathuria, D McCarthy, SA McCarthy, R Meleckyte, Y Memari, N Moens, F Soares, A Mann, I Streeter, CA Agu, A Alderton, R Nelson, S Harper, M Patel, A White, SR Patel, L Clarke, R Halai, CM Kirton, A Kolb-Kokoc, P Beales, E Birney, D Danovi, AI Lamond, WH Ouwehand, L Vallier, FM Watt, R Durbin, O Stegle, DJ Gaffney
Nature, 2017-05-10;546(7658):370-375.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model
Authors: X Yuan, Z Li, AC Baines, E Gavriilaki, Z Ye, Z Wen, EM Braunstein, LG Biesecker, L Cheng, X Dong, RA Brodsky
PLoS ONE, 2017-04-25;12(4):e0174074.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses
Authors: L Guillaud, D Dimitrov, T Takahashi
Elife, 2017-04-22;6(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's disease
Authors: A Kaminari, N Giannakas, A Tzinia, EC Tsilibary
Sci Rep, 2017-04-06;7(1):683.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila
Authors: I Foldi, N Anthoney, N Harrison, M Gangloff, B Verstak, MP Nallasivan, S AlAhmed, B Zhu, M Phizacklea, M Losada-Per, M Moreira, NJ Gay, A Hidalgo
J. Cell Biol., 2017-04-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons
Authors: S Schaller, D Buttigieg, A Alory, A Jacquier, M Barad, M Merchant, D Gentien, P de la Gran, G Haase
Proc. Natl. Acad. Sci. U.S.A, 2017-03-07;114(12):E2486-E2493.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome
Authors: MJ Boland, KL Nazor, HT Tran, A Szücs, CL Lynch, R Paredes, F Tassone, PP Sanna, RJ Hagerman, JF Loring
Brain, 2017-03-01;140(3):582-598.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections
Authors: C Zhong, W Akmentin, C Du, LW Role, DA Talmage
eNeuro, 2017-02-27;4(1):.
Species: Mouse
Sample Types: Complex Sample Type
Applications: Bioassay

Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins
Authors: SP Jenkinson, D Grandgirar, M Heidemann, A Tscherter, MA Avondet, SL Leib
Front Pharmacol, 2017-02-23;8(0):73.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells
Authors: Y Qi, XJ Zhang, N Renier, Z Wu, T Atkin, Z Sun, MZ Ozair, J Tchieu, B Zimmer, F Fattahi, Y Ganat, R Azevedo, N Zeltner, AH Brivanlou, M Karayiorgo, J Gogos, M Tomishima, M Tessier-La, SH Shi, L Studer
Nat. Biotechnol, 2017-01-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neurotoxic reactive astrocytes are induced by activated microglia
Authors: SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE Mnch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres
Nature, 2017-01-18;541(7638):481-487.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased susceptibility to a? toxicity in neuronal cultures derived from familial Azheimer's disease (PSEN1-A246E) induced pluripotent stem cells
Authors: Enrique Armijo
Neurosci. Lett, 2016-12-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson's disease
Authors: M Chumarina, C Azevedo, J Bigarreau, C Vignon, KS Kim, JY Li, L Roybon
Stem Cell Res, 2016-12-22;19(0):17-20.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effects of Feeder Cells on Dopaminergic Differentiation of Human Embryonic Stem Cells
Authors: Z Zhao, Y Ma, Z Chen, Q Liu, Q Li, D Kong, K Yuan, L Hu, T Wang, X Chen, Y Peng, W Jiang, Y Yu, X Liu
Front Cell Neurosci, 2016-12-20;10(0):291.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Time-Course Statistical Evaluation of Intercellular Adhesion Maturation by Femtosecond Laser Impulse
Authors: Yoichiroh Hosokawa
Biophys. J., 2016-11-15;111(10):2255-2262.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016-11-14;22(12):1421-1427.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BDNF Effects on Functional Recovery across Motor Behaviors after Cervical Spinal Cord Injury
Authors: Gary C Sieck
J. Neurophysiol., 2016-11-09;0(0):jn.00654.2016.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Sustained synchronized neuronal network activity in a human astrocyte co-culture system
Sci Rep, 2016-11-07;6(0):36529.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analysis of induced pluripotent stem cells carrying 22q11.2 deletion.
Authors: T Yoshikawa, Hisano Y, Iwayama Y, Toyota T, Itasaka N, Dean B
Transl Psychiatry, 2016-11-01;6(11):e934.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine
Authors: T Nakazawa, M Kikuchi, M Ishikawa, H Yamamori, K Nagayasu, T Matsumoto, M Fujimoto, Y Yasuda, M Fujiwara, S Okada, K Matsumura, A Kasai, A Hayata-Tak, N Shintani, S Numata, K Takuma, W Akamatsu, H Okano, A Nakaya, H Hashimoto, R Hashimoto
Schizophr. Res., 2016-10-27;181(0):75-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs)
Authors: Divya Varun
Acta Biomater, 2016-10-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells
Sci Rep, 2016-09-09;6(0):32532.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS
Stem Cell Res, 2016-08-16;17(3):526-530.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
Sci Rep, 2016-08-10;6(0):31063.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors
Authors: Eva Hedlund
Sci Rep, 2016-06-01;6(0):26448.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Neurotrophin-3 Regulates Synapse Development by Modulating TrkC-PTP? Synaptic Adhesion and Intracellular Signaling Pathways
J Neurosci, 2016-04-27;36(17):4816-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hypomorphism of Fto and Rpgrip1l causes obesity in mice
Authors: G Stratigopo, LC Burnett, R Rausch, R Gill, DB Penn, AA Skowronski, CA LeDuc, AJ Lanzano, P Zhang, DR Storm, D Egli, RL Leibel
J Clin Invest, 2016-04-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Isolation, expansion and neural differentiation of stem cells from human plucked hair: a further step towards autologous nerve recovery
Authors: Margriet A Huisman
Cytotechnology, 2015-12-24;68(5):1849-58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Noggin Over-Expressing Mouse Embryonic Fibroblasts and MS5 Stromal Cells Enhance Directed Differentiation of Dopaminergic Neurons from Human Embryonic Stem Cells.
Authors: Lim M, Shin M, Lee S, Minn Y, Hoh J, Cho Y, Kim D, Lee S, Kim C, Park C
PLoS ONE, 2015-09-18;10(9):e0138460.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Role of Hypoxia-Induced Brain Derived Neurotrophic Factor in Human Pulmonary Artery Smooth Muscle.
Authors: Hartman W, Helan M, Smelter D, Sathish V, Thompson M, Pabelick C, Johnson B, Prakash Y
PLoS ONE, 2015-07-20;10(7):e0129489.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Generation of Dopamine Neurons from Rodent Fibroblasts through the Expandable Neural Precursor Cell Stage.
Authors: Lim M, Chang M, Kim S, Yi S, Suh-Kim H, Jung S, Kim M, Kim J, Lee Y, Lee S, Kim D, Lee S, Park C
J Biol Chem, 2015-05-28;290(28):17401-14.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Authors: Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen J, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T
Nat Neurosci, 2015-04-27;18(6):826-35.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs.
Authors: Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito M
Stem Cell Reports, 2015-03-19;4(4):561-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neuroprotective effects of oligodendrocyte progenitor cell transplantation in premature rat brain following hypoxic-ischemic injury.
Authors: Chen, Long-Xia, Ma, Si-Min, Zhang, Peng, Fan, Zi-Chuan, Xiong, Man, Cheng, Guo-Qian, Yang, Yi, Qiu, Zi-Long, Zhou, Wen-Hao, Li, Jin
PLoS ONE, 2015-03-19;10(3):e0115997.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells.
Authors: Merkle F, Maroof A, Wataya T, Sasai Y, Studer L, Eggan K, Schier A
Development, 2015-02-15;142(4):633-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells.
Authors: Tanaka, Taku, Yokoi, Tadashi, Tamalu, Fuminobu, Watanabe, Shu-Ichi, Nishina, Sachiko, Azuma, Noriyuki
Sci Rep, 2015-02-10;5(0):8344.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability.
Authors: Devlin, Anna-Cla, Burr, Karen, Borooah, Shyamang, Foster, Joshua D, Cleary, Elaine M, Geti, Imbisaat, Vallier, Ludovic, Shaw, Christop, Chandran, Siddhart, Miles, Gareth B
Nat Commun, 2015-01-12;6(0):5999.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
PLoS ONE, 2014-12-26;9(12):e116114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Authors: Wainger B, Buttermore E, Oliveira J, Mellin C, Lee S, Saber W, Wang A, Ichida J, Chiu I, Barrett L, Huebner E, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin L, Eggan K, Woolf C
Nat Neurosci, 2014-11-24;18(1):17-24.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.
Authors: Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Sci Rep, 2014-09-11;4(0):6330.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neuropeptide Y receptor Y5 as an inducible pro-survival factor in neuroblastoma: implications for tumor chemoresistance.
Authors: Czarnecka M, Trinh E, Lu C, Kuan-Celarier A, Galli S, Hong S, Tilan J, Talisman N, Izycka-Swieszewska E, Tsuei J, Yang C, Martin S, Horton M, Christian D, Everhart L, Maheswaran I, Kitlinska J
Oncogene, 2014-08-18;34(24):3131-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs).
Authors: Pre D, Nestor M, Sproul A, Jacob S, Koppensteiner P, Chinchalongporn V, Zimmer M, Yamamoto A, Noggle S, Arancio O
PLoS ONE, 2014-07-29;9(7):e103418.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long-term culture of rat hippocampal neurons at low density in serum-free medium: combination of the sandwich culture technique with the three-dimensional nanofibrous hydrogel PuraMatrix.
Authors: Kaneko A, Sankai Y
PLoS ONE, 2014-07-17;9(7):e102703.
Species: Rat
Sample Types: Whole Tissue
Applications: Bioassay

Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity.
Authors: Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, Dussor G, Price T
Mol Pain, 2014-07-04;10(0):45.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors.
Authors: Terenzio M, Golding M, Russell M, Wicher K, Rosewell I, Spencer-Dene B, Ish-Horowicz D, Schiavo G
EMBO J, 2014-06-11;33(14):1582-98.
Applications: Western Blot

Hybrid multiphoton volumetric functional imaging of large-scale bioengineered neuronal networks.
Authors: Dana, Hod, Marom, Anat, Paluch, Shir, Dvorkin, Roman, Brosh, Inbar, Shoham, Shy
Nat Commun, 2014-06-05;5(0):3997.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling.
Authors: Chang, Ki-Young, Woo, Doyeon, Jung, Hyunjin, Lee, Sangkyu, Kim, Sungsoo, Won, Joungha, Kyung, Taeyoon, Park, Hyerim, Kim, Nury, Yang, Hee Won, Park, Jae-Yong, Hwang, Eun Mi, Kim, Daesoo, Heo, Won Do
Nat Commun, 2014-06-04;5(0):4057.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.
Authors: Ali F, Cheng K, Kirwan P, Metcalfe S, Livesey F, Barker R, Philpott A
Development, 2014-05-12;141(11):2216-24.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Infralimbic BDNF/TrkB enhancement of GluN2B currents facilitates extinction of a cocaine-conditioned place preference.
Authors: Otis J, Fitzgerald M, Mueller D
J Neurosci, 2014-04-23;34(17):6057-64.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors.
Authors: Zhou, Zhi, Kohda, Kazuhisa, Ibata, Keiji, Kohyama, Jun, Akamatsu, Wado, Yuzaki, Michisuk, Okano, Hirotaka, Sasaki, Erika, Okano, Hideyuki
Mol Brain, 2014-04-03;7(0):24.
Species: Primate - Callitrix jacchus (Common Marmoset)
Sample Types: Whole Cells
Applications: Bioassay

Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes.
Authors: Lundgaard I, Luzhynskaya A, Stockley J, Wang Z, Evans K, Swire M, Volbracht K, Gautier H, Franklin R, Attwell D, Karadottir R
PLoS Biol, 2013-12-31;11(12):e1001743.
Species: Rat
Sample Types: Whole Cells
Applications: Cell Culture

Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture.
Authors: Ni, Na, Hu, Yaohua, Ren, Huixia, Luo, Chuanmin, Li, Peng, Wan, Jian-Bo, Su, Huanxing
PLoS ONE, 2013-12-20;8(12):e84504.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.
Authors: Zhong C, Talmage D, Role L
PLoS ONE, 2013-12-05;8(12):e82719.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

A human Dravet syndrome model from patient induced pluripotent stem cells.
Authors: Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori M, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S
Mol Brain, 2013-05-02;6(0):19.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.
Authors: Maroof A, Keros S, Tyson J, Ying S, Ganat Y, Merkle F, Liu B, Goulburn A, Stanley E, Elefanty A, Widmer H, Eggan K, Goldstein P, Anderson S, Studer L
Cell Stem Cell, 2013-05-02;12(5):559-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism.
Authors: Howard, Laura, Wyatt, Sean, Nagappan, Guhan, Davies, Alun M
Development, 2013-05-01;140(10):2108-17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits.
Authors: Liu Y, Weick J, Liu H, Krencik R, Zhang X, Ma L, Zhou G, Ayala M, Zhang S
Nat Biotechnol, 2013-04-21;31(5):440-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.
Authors: Yang Y, Gupta S, Kim K, Powers B, Cerqueira A, Wainger B, Ngo H, Rosowski K, Schein P, Ackeifi C, Arvanites A, Davidow L, Woolf C, Rubin L
Cell Stem Cell, 2013-04-18;12(6):713-26.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
Authors: Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J
Nat Biotechnol, 2013-04-14;31(5):426-33.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.
Authors: Osborne, Jihan K, Larsen, Jill E, Shields, Misty D, Gonzales, Joshua X, Shames, David S, Sato, Mitsuo, Kulkarni, Ashwinik, Wistuba, Ignacio, Girard, Luc, Minna, John D, Cobb, Melanie
Proc Natl Acad Sci U S A, 2013-04-03;110(16):6524-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death.
Authors: Martin, Sally, Harper, Callista, May, Linda M, Coulson, Elizabet, Meunier, Frederic, Osborne, Shona L
PLoS ONE, 2013-03-27;8(3):e60152.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling.
Authors: Gatto G, Dudanova I, Suetterlin P, Davies A, Drescher U, Bixby J, Klein R
J Neurosci, 2013-03-20;33(12):5399-410.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state.
Authors: Melemedjian O, Tillu D, Asiedu M, Mandell E, Moy J, Blute V, Taylor C, Ghosh S, Price T
Mol Pain, 2013-03-20;9(0):12.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

MicroRNA-based promotion of human neuronal differentiation and subtype specification.
Authors: Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O
PLoS ONE, 2013-03-18;8(3):e59011.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Constitutively active TrkB confers an aggressive transformed phenotype to a neural crest-derived cell line.
Authors: Dewitt J, Ochoa V, Urschitz J, Elston M, Moisyadi S, Nishi R
Oncogene, 2013-03-04;33(8):977-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1.
Authors: Denis J, Gauthier M, Rachdi L, Aubert S, Giraud-Triboult K, Poydenot P, Benchoua A, Champon B, Maury Y, Baldeschi C, Scharfmann R, Pietu G, Peschanski M, Martinat C
J Cell Sci, 2013-02-26;126(0):1763-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy.
Authors: Corbett, Grant T, Roy, Avik, Pahan, Kalipada
J Biol Chem, 2013-02-12;288(12):8299-312.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Enrichment and characterization of human dermal stem/progenitor cells by intracellular granularity.
Authors: Shim, Joong Hy, Lee, Tae Ryon, Shin, Dong Woo
Stem Cells Dev, 2013-01-22;22(8):1264-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling.
Authors: Makino, Kenichi, Kawamura, Kazuhiro, Sato, Wataru, Kawamura, Nanami, Fujimoto, Toshio, Terada, Yukihiro
PLoS ONE, 2012-07-23;7(7):e41049.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
J. Biol. Chem., 2011-07-07;286(34):30034-46.
Species: Human, Mouse
Sample Types: Recombinant Protein
Applications: Surface Plasmon Resonance

E-cadherin-expressing feeder cells promote neural lineage restriction of human embryonic stem cells.
Authors: Moore RN, Cherry JF, Mathur V
Stem Cells Dev., 2011-06-01;21(1):30-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The suppressive effect of an intra-prefrontal cortical infusion of BDNF on cocaine-seeking is Trk receptor and extracellular signal-regulated protein kinase mitogen-activated protein kinase dependent.
Authors: Whitfield TW, Shi X, Sun WL
J. Neurosci., 2011-01-19;31(3):834-42.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1.
Authors: Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, D'Hooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chedotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C
J. Neurosci., 2010-11-10;30(45):15052-66.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells.
Authors: Delcroix GJ, Curtis KM, Schiller PC, Montero-Menei CN
Differentiation, 2010-09-01;80(4):213-27.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens.
Authors: Berglind WJ, Whitfield TW, LaLumiere RT, Kalivas PW, McGinty JF
J. Neurosci., 2009-03-25;29(12):3715-9.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Brain-derived neurotrophic factor stimulates bone/cementum-related protein gene expression in cementoblasts.
Authors: Kajiya M, Shiba H, Fujita T, Ouhara K, Takeda K, Mizuno N, Kawaguchi H, Kitagawa M, Takata T, Tsuji K, Kurihara H
J. Biol. Chem., 2008-04-03;283(23):16259-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture.
Authors: Sun Y, Pollard S, Conti L, Toselli M, Biella G, Parkin G, Willatt L, Falk A, Cattaneo E, Smith A
Mol. Cell. Neurosci., 2008-03-18;38(2):245-58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
Authors: Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L
Genes Dev., 2008-01-15;22(2):152-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neurotrophins modulate monocyte chemotaxis without affecting macrophage function.
Authors: Samah B, Porcheray F, Gras G
Clin. Exp. Immunol., 2008-01-08;151(3):476-86.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A highly enriched niche of precursor cells with neuronal and glial potential within the hair follicle dermal papilla of adult skin.
Authors: Hunt DP, Morris PN, Sterling J, Anderson JA, Joannides A, Jahoda C, Compston A, Chandran S
Stem Cells, 2007-09-27;26(1):163-72.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.
Authors: Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP
Development, 2007-09-01;134(18):3327-38.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

A BDNF infusion into the medial prefrontal cortex suppresses cocaine seeking in rats.
Authors: Berglind WJ, See RE, Fuchs RA, Ghee SM, Whitfield TW, Miller SW, McGinty JF
Eur. J. Neurosci., 2007-07-25;26(3):757-66.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

BDNF plasma levels in acute stroke.
Authors: Di Lazzaro V, Profice P, Pilato F, Dileone M, Florio L, Tonali PA, Angelucci F
Neurosci. Lett., 2007-06-08;422(2):128-30.
Applications: ELISA (Standard)

Differentiation of ES cells into cerebellar neurons.
Authors: Salero E, Hatten ME
Proc. Natl. Acad. Sci. U.S.A., 2007-02-09;104(8):2997-3002.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat.
Authors: Paredes D, Granholm AC, Bickford PC
Brain Res., 2007-01-12;1141(0):56-64.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Multipotent adult progenitor cells from swine bone marrow.
Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
Stem Cells, 2006-08-24;24(11):2355-66.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay

Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions.
Authors: Mohapel P, Frielingsdorf H, Haggblad J, Zachrisson O, Brundin P
Neuroscience, 2005-01-01;132(3):767-76.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Derivation of midbrain dopamine neurons from human embryonic stem cells.
Authors: Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L
Proc. Natl. Acad. Sci. U.S.A., 2004-08-13;101(34):12543-8.
Species: Human, Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay