Recombinant Mouse IFN-gamma Protein

Upadacitinib inhibits corneal inflammation and neovascularization by suppressing M1 macrophage infiltration in the corneal alkali burn model
Authors: J Yu, Y Shen, J Luo, J Jin, P Li, P Feng, H Guan
International immunopharmacology, 2023-02-03;116(0):109680.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway
Authors: WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee
International Journal of Molecular Sciences, 2023-01-29;24(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Immunoproteasome inhibition prevents progression of castration-resistant prostate cancer
Authors: J Li, N Liu, H Zhou, P Xian, Y Song, X Tang, Y Li, M Basler
British Journal of Cancer, 2023-01-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells
Authors: YS Song, N Jamali, CM Sorenson, N Sheibani
Cells, 2023-01-16;12(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy
Authors: X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, M Dougan, L Su, X Zhao, J Piehler, KC Garcia
Nature Biotechnology, 2023-01-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy
Authors: X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, M Dougan, L Su, X Zhao, J Piehler, KC Garcia
Nature Biotechnology, 2023;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes
Authors: V Göser, N Sander, M Schulte, F Scharte, R Franzkoch, V Liss, OE Psathaki, M Hensel
Nature Communications, 2023;14(1):1240.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway
Authors: WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee
International Journal of Molecular Sciences, 2023;24(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pancreatic Islet Cells Response to IFNgamma Relies on Their Spatial Location within an Islet
Authors: M De Burghgr, C Lourenço, C Berthault, V Aiello, A Villalba, A Fouque, M Diedisheim, S You, M Oshima, R Scharfmann
Cells, 2022-12-28;12(1):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Astragaloside IV Targets Macrophages to Alleviate Renal Ischemia-Reperfusion Injury via the Crosstalk between Hif-1alpha and NF-kappaB (p65)/Smad7 Pathways
Authors: L Tang, M Zhu, X Che, X Yang, Y Xu, Q Ma, M Zhang, Z Ni, X Shao, S Mou
Journal of personalized medicine, 2022-12-27;13(1):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Near-Infrared Mechanically Switchable Elastomeric Film as a Dynamic Cell Culture Substrate
Authors: G Spiaggia, P Taladriz-B, S Hengsberge, D Septiadi, C Geers, A Lee, B Rothen-Rut, A Petri-Fink
Biomedicines, 2022-12-22;11(1):.
Species: Mouse
Sample Types: cell culture supernatant
Applications: ELISA Control

Zinc Transporter 8 Haploinsufficiency Protects Against Beta Cell Dysfunction in Type 1 Diabetes by Increasing Mitochondrial Respiration
Authors: YK Kim, JA Walters, ND Moss, KL Wells, R Sheridan, JG Miranda, RKP Benninger, LL Pyle, RM O'Brien, L Sussel, HW Davidson
Molecular Metabolism, 2022-11-05;66(0):101632.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair
Authors: P Wang, Z Huang, Y Peng, H Li, T Lin, Y Zhao, Z Hu, Z Zhou, W Zhou, Y Liu, FF Hou
Nature Communications, 2022-10-31;13(1):6502.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Desmoglein-2 is important for islet function and beta-cell survival
Authors: KK Myo Min, D Rojas-Cana, D Penko, M DeNichilo, MP Cockshell, CB Ffrench, EJ Thompson, O Asplund, CJ Drogemulle, RB Prasad, L Groop, ST Grey, HE Thomas, T Loudovaris, TW Kay, MG Mahoney, CF Jessup, PT Coates, CS Bonder
Cell Death & Disease, 2022-10-29;13(10):911.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNFalpha and IFNgamma cooperate for efficient pro- to anti-inflammatory transition of macrophages during muscle regeneration
Authors: F Babaeijand, A Paiero, R Long, LW Tung, SP Smith, R Cheng, J Smandych, N Kajabadi, CK Chang, A Ghassemi, WDM Kennedy, H Soliman, PW Schutz, FMV Rossi
Proceedings of the National Academy of Sciences of the United States of America, 2022-10-24;119(44):e2209976119.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target
Authors: H Cho, HY Kwon, A Sharma, SH Lee, X Liu, N Miyamoto, JJ Kim, SH Im, NY Kang, YT Chang
Nature Communications, 2022-10-10;13(1):5974.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses
Authors: AP Shaik, AS Shaik, M Abudawood, A Al Faraj
BioMed Research International, 2022-10-06;2022(0):9470845.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Neuronally expressed PDL1, not PD1, suppresses acute nociception
Authors: KA Meerschaer, BS Edwards, AY Epouhe, B Jefferson, R Friedman, OL Babyok, JK Moy, F Kehinde, C Liu, CJ Workman, DAA Vignali, KM Albers, HR Koerber, MS Gold, BM Davis, NN Scheff, JL Saloman
Brain, Behavior, and Immunity, 2022-09-08;106(0):233-246.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling
Authors: N Zoellner, N Coesfeld, FH De Vos, J Denter, HC Xu, E Zimmer, B Knebel, H Al-Hasani, S Mossner, PA Lang, DM Floss, J Scheller
Frontiers in Microbiology, 2022-09-02;13(0):947169.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice
Authors: I Mhatre-Win, A Eid, Y Han, K Tieu, JR Richardson
International Journal of Molecular Sciences, 2022-08-29;23(17):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Twist-related protein 1 induces epithelial-mesenchymal transition and renal fibrosis through the upregulation of complement 3
Authors: T Otsuki, N Fukuda, L Chen, A Tsunemi, M Abe
PLoS ONE, 2022-08-26;17(8):e0272917.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity
Authors: T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo
Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119.
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture

STUB1 is an intracellular checkpoint for interferon gamma sensing
Authors: S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge
Scientific Reports, 2022-08-18;12(1):14087.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii
Authors: S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy
Nature Communications, 2022-08-08;13(1):4605.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
Authors: EG Vasquez, N Nasreddin, GN Valbuena, EJ Mulholland, HL Belnoue-Da, HR Eggington, RO Schenck, VM Wouters, P Wirapati, K Gilroy, TRM Lannagan, DJ Flanagan, AK Najumudeen, S Omwenga, AMB McCorry, A Easton, VH Koelzer, JE East, D Morton, L Trusolino, T Maughan, AD Campbell, MB Loughrey, PD Dunne, P Tsantoulis, DJ Huels, S Tejpar, OJ Sansom, SJ Leedham
Cell Stem Cell, 2022-08-04;29(8):1213-1228.e8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal beta cells
Authors: MB Bayazit, C Jacovetti, C Cosentino, J Sobel, K Wu, F Brozzi, A Rodriguez-, L Stoll, C Guay, R Regazzi
Cell Reports, 2022-07-12;40(2):111069.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation
Authors: R Guo, X Jia, Z Ding, G Wang, M Jiang, B Li, S Chen, B Xia, Q Zhang, J Liu, R Zheng, Z Gao, X Xie
Theranostics, 2022-07-04;12(11):5220-5236.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload
Authors: MK Ameka, WN Beavers, CM Shaver, LB Ware, VE Kerchberge, KQ Schoenfelt, L Sun, T Koyama, EP Skaar, L Becker, AH Hasty
International Journal of Molecular Sciences, 2022-07-03;23(13):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects
Authors: R Mary, F Chalmin, T Accogli, M Bruchard, C Hibos, J Melin, C Truntzer, E Limagne, V Derangère, M Thibaudin, E Humblin, R Boidot, S Chevrier, L Arnould, C Richard, Q Klopfenste, A Bernard, Y Urade, JA Harker, L Apetoh, F Ghiringhel, F Végran
Cancer Immunology Research, 2022-07-01;0(0):OF1-OF17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors
Authors: G Coquant, D Aguanno, L Brot, C Belloir, J Delugeard, N Roger, HP Pham, L Briand, M Moreau, L de Sordi, V Carrière, JP Grill, S Thenet, P Seksik
Oncogene, 2022-06-08;12(1):9440.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
Authors: H Qu, R Heinbäck, H Salo, E Ewing, A Espinosa, C Aulin, H Erlandsson
Biomolecules, 2022-06-02;12(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement
Authors: H Kamei, T Ishii, Y Nishii
Oncogene, 2022-06-02;12(1):9243.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis
Authors: Y Jin, Y Liu, L Xu, J Xu, Y Xiong, Y Peng, K Ding, S Zheng, N Yang, Z Zhang, L Li, L Tan, H Song, J Fu
Cell Death & Disease, 2022-05-31;13(5):512.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A TLR4-independent critical role for CD14 in intracellular LPS sensing
Authors: SO Vasudevan, AJ Russo, P Kumari, SK Vanaja, VA Rathinam
Cell Reports, 2022-05-03;39(5):110755.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Deficiency in coatomer complex I causes aberrant activation of STING signalling
Authors: A Steiner, K Hrovat-Sch, I Prigione, CH Yu, P Laohamonth, CR Harapas, RRJ Low, D De Nardo, LF Dagley, MJ Mlodzianos, KL Rogers, T Zillinger, G Hartmann, MP Gantier, M Gattorno, M Geyer, S Volpi, S Davidson, SL Masters
Nature Communications, 2022-04-28;13(1):2321.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
Authors: W Piao, L Li, V Saxena, J Iyyathurai, R Lakhan, Y Zhang, IT Lape, C Paluskievi, KL Hippen, Y Lee, E Silverman, MW Shirkey, LV Riella, BR Blazar, JS Bromberg
Nature Communications, 2022-04-21;13(1):2176.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Citrullination of glucokinase is linked to autoimmune diabetes
Authors: ML Yang, S Horstman, R Gee, P Guyer, TT Lam, J Kanyo, AL Perdigoto, C Speake, CJ Greenbaum, A Callebaut, L Overbergh, RG Kibbey, KC Herold, EA James, MJ Mamula
Nature Communications, 2022-04-06;13(1):1870.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response
Authors: A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng
Cancer Immunology Research, 2022-04-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs
Authors: L Liu, RM Lucas, JD Nanson, Y Li, J Whitfield, JEB Curson, N Tuladhar, K Alexandrov, M Mobli, MJ Sweet, B Kobe, J Stow, L Luo
The Journal of Biological Chemistry, 2022-03-22;0(0):101857.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ferroptosis as a Novel Determinant of beta-Cell Death in Diabetic Conditions
Authors: A Stancic, T Saksida, M Markelic, M Vucetic, I Grigorov, V Martinovic, D Gajic, A Ivanovic, K Velickovic, N Savic, V Otasevic
Oxidative Medicine and Cellular Longevity, 2022-03-14;2022(0):3873420.
Species: Rat
Sample Types: Whole Cells
Applications: Cell Culture

Recruitment and training of alveolar macrophages after pneumococcal pneumonia
Authors: EI Arafa, AT Shenoy, KA Barker, NS Etesami, IM Martin, C Lyon De An, E Na, CV Odom, WN Goltry, FT Korkmaz, AK Wooten, AC Belkina, A Guillon, EC Forsberg, MR Jones, LJ Quinton, JP Mizgerd
JCI Insight, 2022-03-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
Authors: SW Tuffs, MI Goncheva, SX Xu, HC Craig, KJ Kasper, J Choi, RS Flannagan, SM Kerfoot, DE Heinrichs, JK McCormick
Proceedings of the National Academy of Sciences of the United States of America, 2022-02-22;119(8):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model
Authors: J Jin, I Sivakumar, Y Mironchik, B Krishnamac, F Wildes, JD Barnett, CF Hung, S Nimmagadda, H Kobayashi, ZM Bhujwalla, MF Penet
Cancers, 2022-01-26;14(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Insights from Dysregulated mRNA Expression Profile of beta-Cells in Response to Proinflammatory Cytokines
Authors: Z Wang, K Huang, J Xu, J Liu, Y Zheng
Journal of Immunology Research, 2022-01-22;2022(0):4542487.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CXCR4 induces podocyte injury and proteinuria by activating beta-catenin signaling
Authors: H Mo, Q Ren, D Song, B Xu, D Zhou, X Hong, FF Hou, L Zhou, Y Liu
Theranostics, 2022-01-01;12(2):767-781.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dynamic changes in beta-cell [Ca2+] regulates NFAT activation, gene transcription and islet gap junction communication
Authors: JG Miranda, WE Schleicher, KL Wells, DG Ramirez, SP Landgrave, RK Benninger
Oncogene, 2021-12-31;0(0):101430.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes
Authors: HR McMurray, A Ambeskovic, LA Newman, J Aldersley, V Balakrishn, B Smith, HA Stern, H Land, MN McCall
Cell Reports, 2021-12-21;37(12):110136.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease
Authors: Y Cheng, TR Hall, X Xu, I Yung, D Souza, J Zheng, F Schiele, M Hoffmann, ML Mbow, JP Garnett, J Li
EBioMedicine, 2021-12-18;75(0):103758.
Species: Mouse, Transgenic Mouse
Sample Types: Organoid
Applications: Bioassay

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
Cell Reports, 2021-11-23;37(8):110037.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
Authors: KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng
Nature Communications, 2021-11-17;12(1):6637.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differential Cytokine-Induced Responses of Polarized Microglia
Authors: P Chauhan, WS Sheng, S Hu, S Prasad, JR Lokensgard
Brain sciences, 2021-11-10;11(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of intestinal immunity and tissue repair by enteric glia
Authors: F Progatzky, M Shapiro, SH Chng, B Garcia-Cas, CH Classon, S Sevgi, A Laddach, AC Bon-Frauch, R Lasrado, M Rahim, EM Amaniti, S Boeing, K Shah, LJ Entwistle, A Suárez-Bon, MS Wilson, B Stockinger, V Pachnis
Nature, 2021-10-20;599(7883):125-130.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair
Authors: Y Zhang, Y Zheng, F Shu, R Zhou, B Bao, S Xiao, K Li, Q Lin, L Zhu, Z Xia
Carbohydrate polymers, 2021-10-16;276(0):118752.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lung Fibrosis Is Improved by Extracellular Vesicles from IFNgamma-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis
Authors: P Rozier, M Maumus, ATJ Maria, K Toupet, C Jorgensen, P Guilpain, D Noël
Cells, 2021-10-13;10(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation
Authors: JM Motta, VM Rumjanek, A Mantovani, M Locati
Biomedicines, 2021-10-04;9(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury
Authors: J Amo-Aparic, J Garcia-Gar, I Francos-Qu, A Urpi, A Esteve-Cod, M Gut, A Quintana, R Lopez-Vale
Theranostics, 2021-10-03;11(20):9805-9820.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis
Authors: G Wang, L Xie, B Li, W Sang, J Yan, J Li, H Tian, W Li, Z Zhang, Y Tian, Y Dai
Nature Communications, 2021-09-30;12(1):5733.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea
Authors: TD Popoola, ST Guetchueng, KJ Ritchie, O Awodele, NM Dempster, O Akinloye, SD Sarker, AA Fatokun
BMC complementary medicine and therapies, 2021-09-18;21(1):234.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota
Authors: S Lee, G Kalugotla, H Ingle, R Rodgers, C Wu, Y Wang, Y Li, X Yang, J Zhang, NR Borella, H Deng, L Droit, R Hill, ST Peterson, C Desai, D Lawrence, Q Lu, MT Baldridge
Autophagy, 2021-09-14;0(0):1-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways
Authors: A Gluschko, A Farid, M Herb, D Grumme, M Krönke, M Schramm
Autophagy, 2021-09-05;0(0):1-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe-/- Mice through Modulating Macrophage Functions
Authors: Z Qian, H Yang, H Li, C Liu, L Yang, Z Qu, X Li
Biomedicines, 2021-09-03;9(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium
Authors: M Choi, JA Bonanno
Investigative Ophthalmology & Visual Science, 2021-09-02;62(12):4.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
Authors: A Osman, B Yan, Y Li, KD Pavelko, J Quandt, A Saadalla, MP Singh, M Kazemian, F Gounari, K Khazaie
Nature Immunology, 2021-08-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

alpha-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFalpha/IFNgamma Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube
Authors: K Sumi, M Sakuda, K Munakata, K Nakamura, K Ashida
Nutrients, 2021-07-13;13(7):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects
Authors: J Sadek, DT Hall, B Colalillo, A Omer, AK Tremblay, V Sanguin-Ge, W Muller, S Di Marco, ME Bianchi, IE Gallouzi
Embo Molecular Medicine, 2021-06-07;0(0):e13591.
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

Protective Effects of Complement Component 8 Gamma Against Blood-Brain Barrier Breakdown
Authors: JH Kim, J Han, K Suk
Frontiers in Physiology, 2021-06-03;12(0):671250.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Cultulre

STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
Authors: SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie
Nature Communications, 2021-06-03;12(1):3299.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice
Authors: MB Preda, CA Neculachi, IM Fenyo, AM Vacaru, MA Publik, M Simionescu, A Burlacu
Cell Death & Disease, 2021-06-02;12(6):566.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The YAP/HIF-1&alpha/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation
Authors: J Zhou, N Zhang, W Zhang, C Lu, F Xu
Cell & bioscience, 2021-05-12;11(1):84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The ubiquitylation of IL-1&beta limits its cleavage by caspase-1 and targets it for proteasomal degradation
Authors: SL Vijayaraj, R Feltham, M Rashidi, D Frank, Z Liu, DS Simpson, G Ebert, A Vince, MJ Herold, A Kueh, JS Pearson, LF Dagley, JM Murphy, AI Webb, KE Lawlor, JE Vince
Nature Communications, 2021-05-11;12(1):2713.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model
Authors: SS Qin, BJ Han, A Williams, KM Jackson, R Jewell, AC Chacon, EM Lord, DC Linehan, M Kim, A Reuben, SA Gerber, PA Prieto
Cancers, 2021-05-11;13(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Involvement of circRNAs in Proinflammatory Cytokines-Mediated &beta-Cell Dysfunction
Authors: Z Wang, C Deng, Y Zheng
Mediators of Inflammation, 2021-05-04;2021(0):5566453.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

N4BP1 negatively regulates NF-&kappaB by binding and inhibiting NEMO oligomerization
Authors: H Shi, L Sun, Y Wang, A Liu, X Zhan, X Li, M Tang, P Anderton, S Hildebrand, J Quan, S Ludwig, EMY Moresco, B Beutler
Nature Communications, 2021-03-02;12(1):1379.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer
Authors: P Tallón de, H Castañón, M Vermeer, N Núñez, K Silina, B Sobottka, J Urdinez, V Cecconi, H Yagita, F Movahedian, S Hiltbrunne, I Glarner, H Moch, S Tugues, B Becher, M van den Br
Nature Communications, 2021-02-03;12(1):769.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress
Authors: M Ichii, K Oritani, J Toda, H Saito, H Shi, H Shibayama, D Motooka, Y Kitai, R Muromoto, JI Kashiwakur, K Saitoh, D Okuzaki, T Matsuda, Y Kanakura
Haematologica, 2021-02-01;0(0):.
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture

T-bet-dependent ILC1- and NK cell-derived IFN-&gamma mediates cDC1-dependent host resistance against Toxoplasma gondii
Authors: AH López-Ygle, E Burger, E Camanzo, AT Martin, AM Araujo, SF Kwok, F Yarovinsky
PloS Pathogens, 2021-01-19;17(1):e1008299.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

Gut-licensed IFN&gamma+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
Authors: LM Sanmarco, MA Wheeler, C Gutiérrez-, CM Polonio, M Linnerbaue, FA Pinho-Ribe, Z Li, F Giovannoni, KV Batterman, G Scalisi, SEJ Zandee, ES Heck, M Alsuwailm, DL Rosene, B Becher, IM Chiu, A Prat, FJ Quintana
Nature, 2021-01-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
Authors: R Contreras-, R Elizondo-V, N Luque-Camp, MJ Torres, C Pradenas, G Tejedor, MJ Paredes-Ma, AM Vega-Lette, M Campos-Mor, Y Rigual-Gon, K Oyarce, M Salgado, C Jorgensen, M Khoury, MLÁ Garcia-Rob, C Altamirano, F Djouad, P Luz-Crawfo
Theranostics, 2021-01-01;11(1):445-460.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells
Authors: SA Rajput, MR Mirza, MI Choudhary
PLoS ONE, 2020-12-21;15(12):e0241349.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics
Authors: JV Carratalá, E Brouillett, N Serna, A Sánchez-Ch, JM Sánchez, A Villaverde, A Arís, E Garcia-Fru, N Ferrer-Mir, F Malouin
Pharmaceutics, 2020-12-17;12(12):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome
Authors: KD Tuttle, KA Waugh, P Araya, R Minter, DJ Orlicky, M Ludwig, Z Andrysik, MA Burchill, BAJ Tamburini, C Sempeck, K Smith, R Granrath, D Tracy, J Baxter, JM Espinosa, KD Sullivan
Cell Rep, 2020-11-17;33(7):108407.
Species: Mouse
Sample Types: Plasma
Applications: Cell Culture

Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its anti-inflammatory properties
Authors: CY Han, I Kang, M Omer, S Wang, T Wietecha, TN Wight, A Chait
JCI Insight, 2020-09-24;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The innate immunity protein IFITM3 modulates &gamma-secretase in Alzheimer's disease
Authors: JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, Y Zhai, JC Wang, J Tcw, L Guo, A McKenzie, C Ming, X Zhou, M Wang, Y Sagi, AE Renton, BT Esposito, Y Kim, KR Sadleir, I Trinh, RA Rissman, R Vassar, B Zhang, DS Johnson, E Masliah, P Greengard, A Goate, YM Li
Nature, 2020-09-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models
Authors: K Nolan, G Verzosa, T Cleaver, D Tippimanch, LN DePledge, XJ Wang, C Young, A Le, R Doebele, H Li, SP Malkoski
Cancer Cell Int., 2020-08-28;20(0):417.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ectonucleotidases from trypomastigotes from different sources and various genetic backgrounds of Trypanosoma cruzi potentiate their infectivity and host inflammation
Authors: ALJ Leite, DS Oliveira, LWR Mota, LCF Carvalho, FF Zimmermann, NCN Paiva, PMA Vieira, M de Lana, LCC Afonso, A Talvani
Cytokine, 2020-08-28;136(0):155255.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
Authors: J Tur, S Pereira-Lo, T Vico, EA Marín, JP Muñoz, M Hernández-, PJ Cardona, A Zorzano, J Lloberas, A Celada
Cell Rep, 2020-08-25;32(8):108079.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lipid mediators and biomarkers associated with type 1 diabetes development
Authors: AJ Nelson, DJ Stephenson, RN Bone, CL Cardona, MA Park, YG Tusing, X Lei, G Kokotos, CL Graves, CE Mathews, J Kramer, MJ Hessner, CE Chalfant, S Ramanadham
JCI Insight, 2020-08-20;5(16):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Unique molecular characteristics of visceral afferents arising from different levels of the neuraxis: location of afferent somata predicts function and stimulus detection modalities
Authors: KA Meerschaer, PC Adelman, RL Friedman, KM Albers, HR Koerber, BM Davis
J. Neurosci., 2020-08-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

Triacylglycerol synthesis enhances macrophage inflammatory function
Authors: A Castoldi, LB Monteiro, N van Teijli, DE Sanin, N Rana, M Corrado, AM Cameron, F Hässler, M Matsushita, G Caputa, RI Klein Gelt, J Büscher, J Edwards-Hi, EL Pearce, EJ Pearce
Nat Commun, 2020-08-14;11(1):4107.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lipopolysaccharide administration for a mouse model of cerebellar ataxia with neuroinflammation
Authors: J Hong, D Yoon, Y Nam, D Seo, JH Kim, MS Kim, TY Lee, KS Kim, PW Ko, HW Lee, K Suk, SR Kim
Sci Rep, 2020-08-07;10(1):13337.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression
Authors: JPM Luiz, JE Toller-Kaw, PR Viacava, DC Nascimento, PT Pereira, AL Saraiva, DS Prado, M LeBert, E Giurisato, C Tournier, TM Cunha, FQ Cunha, V Quesniaux, B Ryffel, JC Alves-Filh
J. Leukoc. Biol., 2020-08-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury
Authors: S Ettou, YL Jung, T Miyoshi, D Jain, K Hiratsuka, V Schumacher, ME Taglienti, R Morizane, PJ Park, JA Kreidberg
Sci Adv, 2020-07-24;6(30):eabb5460.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages
Authors: R Kapetanovi, SF Afroz, D Ramnath, GM Lawrence, T Okada, JE Curson, J de Bruin, DP Fairlie, K Schroder, JC St John, A Blumenthal, MJ Sweet
Immunol. Cell Biol., 2020-07-20;0(0):.
Species: Mouse
Sample Types: Cells
Applications: Cell Culture

Ciliary proteins specify the cell inflammatory response by tuning NF&kappaB signalling, independently of primary cilia
Authors: M Mc Fie, L Koneva, I Collins, CR Coveney, AM Clube, A Chanalaris, TL Vincent, JS Bezbradica, SN Sansom, AKT Wann
J. Cell. Sci., 2020-07-08;133(13):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-O-&beta-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells
Authors: YH Wen, JN Lin, RS Wu, SH Yu, CJ Hsu, GF Tseng, HP Wu
Molecules, 2020-07-06;25(13):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
Cell Rep, 2020-06-30;31(13):107820.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity
Authors: CY Han, I Kang, IA Harten, JA Gebe, CK Chan, M Omer, KM Alonge, LJ den Hartig, D Gomes Kjer, L Goodspeed, S Subramania, S Wang, F Kim, DE Birk, TN Wight, A Chait
Cell Rep, 2020-06-30;31(13):107818.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2
Authors: A Chaparala, H Tashkandi, AA Chumanevic, EE Witalison, A Windust, T Cui, M Nagarkatti, P Nagarkatti, LJ Hofseth
Nutrients, 2020-06-21;12(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
Authors: JM Hildebrand, M Kauppi, IJ Majewski, Z Liu, AJ Cox, S Miyake, EJ Petrie, MA Silk, Z Li, MC Tanzer, G Brumatti, SN Young, C Hall, SE Garnish, J Corbin, MD Stutz, L Di Rago, P Gangatirka, EC Josefsson, K Rigbye, H Anderton, JA Rickard, A Tripaydoni, J Sheridan, TS Scerri, VE Jackson, PE Czabotar, JG Zhang, L Varghese, CC Allison, M Pellegrini, GM Tannahill, EC Hatchell, TA Willson, D Stockwell, CA de Graaf, J Collinge, A Hilton, N Silke, SK Spall, D Chau, V Athanasopo, D Metcalf, RM Laxer, AG Bassuk, BW Darbro, MA Fiatarone, N Vlahovich, D Hughes, M Kozlovskai, DB Ascher, K Warnatz, N Venhoff, J Thiel, C Biben, S Blum, J Reveille, MS Hildebrand, CG Vinuesa, P McCombe, MA Brown, BT Kile, C McLean, M Bahlo, SL Masters, H Nakano, PJ Ferguson, JM Murphy, WS Alexander, J Silke
Nat Commun, 2020-06-19;11(1):3150.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Immunopathology in schistosomiasis is regulated by TLR2,4- and IFN-gamma-activated MSC through modulating Th1/Th2 responses
Authors: C Liu, YS Zhang, F Chen, XY Wu, BB Zhang, ZD Wu, JX Lei
Stem Cell Res Ther, 2020-06-05;11(1):217.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice
Authors: A Chaparala, D Poudyal, H Tashkandi, EE Witalison, AA Chumanevic, JL Hofseth, I Nguyen, O Hardy, DL Pittman, MD Wyatt, A Windust, EA Murphy, M Nagarkatti, P Nagarkatti, LJ Hofseth
Oncotarget, 2020-06-02;11(22):2026-2036.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis
Authors: M Li, C Li, X Wu, T Chen, L Ren, B Xu, J Cao
Crit Care, 2020-05-27;24(1):268.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Paracrine regulation and improvement of &beta-cell function by thioredoxin
Authors: EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn
Redox Biol, 2020-05-16;34(0):101570.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation
Authors: Q Yuan, J Miao, Q Yang, L Fang, Y Fang, H Ding, Y Zhou, L Jiang, C Dai, K Zen, Q Sun, J Yang
Cell Death Dis, 2020-05-11;11(5):355.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Authors: Bosteels C, Neyt K, Vanheerswynghels M, van Helden M, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams D, Tang S, Mayer J, Ronchese F, Scott C, Hammad H, Guilliams M, Lambrecht B
Immunity, 2020-05-08;0(0):.
Species: Mouse
Sample Types: cell culture

Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells
Authors: J Falero-Per, N Sheibani, CM Sorenson
PLoS ONE, 2020-05-04;15(5):e0232779.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

2,3,4',5-Tetrahydroxystilbene-2-O-&beta-D-Glucoside (THSG) Activates the Nrf2 Antioxidant Pathway and Attenuates Oxidative Stress-Induced Cell Death in Mouse Cochlear UB/OC-2 Cells
Authors: TY Wu, JN Lin, ZY Luo, CJ Hsu, JS Wang, HP Wu
Biomolecules, 2020-03-18;10(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
Authors: R Kumar, PT Bunn, SS Singh, SS Ng, M Montes de, F De Labasti, SB Chauhan, N Singh, RJ Faleiro, CL Edwards, TCM Frame, M Sheel, RJ Austin, SW Lane, T Bald, MJ Smyth, GR Hill, SE Best, A Haque, D Corvino, N Waddell, L Koufarioti, P Mukhopadha, M Rai, J Chakravart, OP Singh, D Sacks, S Nylen, J Uzonna, S Sundar, CR Engwerda
Cell Rep, 2020-02-25;30(8):2512-2525.e9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury
Authors: J Giri, R Das, E Nylen, R Chinnadura, J Galipeau
Cell Rep, 2020-02-11;30(6):1923-1934.e4.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

N6-methyladenosine demethylase FTO promotes M1 and M2 macrophage activation
Authors: X Gu, Y Zhang, D Li, H Cai, L Cai, Q Xu
Cell. Signal., 2020-02-01;0(0):109553.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells
Authors: S Steinmann, M Schoedsack, F Heinrich, PC Breda, A Ochel, G Tiegs, K Neumann
Sci Rep, 2020-01-23;10(1):1071.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway
Authors: V Delprat, C Tellier, C Demazy, M Raes, O Feron, C Michiels
Sci Rep, 2020-01-21;10(1):882.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection
Authors: N Steffens, C Beuter-Gun, E Kravets, A Reich, L Legewie, K Pfeffer, D Degrandi
MBio, 2020-01-21;11(1):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-kappaB Activation for Antibody Class-Switching
Authors: H Yan, M Fernandez, J Wang, S Wu, R Wang, Z Lou, JB Moroney, CE Rivera, JR Taylor, H Gan, H Zan, D Kolvaskyy, D Liu, P Casali, Z Xu
J. Immunol., 2020-01-13;204(5):1146-1157.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
Authors: K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito
BMC Cancer, 2020-01-08;20(1):25.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-gamma-induced immune destruction of hematopoiesis in bone marrow cells
Authors: J Liu, J Wei, C Wang, X Meng, H Chen, P Deng, M Huandike, H Zhang, X Li, L Chai
BMC Complement Altern Med, 2019-12-09;19(1):356.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment
Authors: J Augustine, S Pavlou, I Ali, K Harkin, E Ozaki, M Campbell, AW Stitt, H Xu, M Chen
J Neuroinflammation, 2019-12-03;16(1):251.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress
Authors: H Ben-Yehuda, O Matcovitch, A Kertser, A Spinrad, M Prinz, I Amit, M Schwartz
Mol. Psychiatry, 2019-11-26;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

A20 as an immune tolerance factor can determine islet transplant outcomes
Authors: NW Zammit, SN Walters, KL Seeberger, PJ O'Connell, GS Korbutt, ST Grey
JCI Insight, 2019-11-01;4(21):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Metabolic regulation of gene expression by histone lactylation
Authors: D Zhang, Z Tang, H Huang, G Zhou, C Cui, Y Weng, W Liu, S Kim, S Lee, M Perez-Neut, J Ding, D Czyz, R Hu, Z Ye, M He, YG Zheng, HA Shuman, L Dai, B Ren, RG Roeder, L Becker, Y Zhao
Nature, 2019-10-23;574(7779):575-580.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

The combination of Cytokines and albendazole therapy for prophylaxis and treatment of experimental./hydatid cyst
Authors: M Rahdar, A Rafiei, R Valipour-N
Acta Trop., 2019-10-02;201(0):105206.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury
Authors: C Claser, SYT Nguee, A Balachande, S Wu Howland, E Becht, B Gunasegara, SV Hartimath, AWQ Lee, J Theng Then, C Bing Ong, EW Newell, J Goggi, L Guan Ng, L Renia
Nat Commun, 2019-09-18;10(1):4241.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis
Authors: Y Xu, Y Xu, Y Zhu, H Sun, C Juguilon, F Li, D Fan, L Yin, Y Zhang
Mol. Ther., 2019-09-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Phlda3 regulates beta cell survival during stress
Authors: M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt
Sci Rep, 2019-09-06;9(1):12827.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease
Authors: P Krashia, A Cordella, A Nobili, L La Barbera, M Federici, A Leuti, F Campanelli, G Natale, G Marino, V Calabrese, F Vedele, V Ghiglieri, B Picconi, G Di Lazzaro, T Schirinzi, G Sancesario, N Casadei, O Riess, S Bernardini, A Pisani, P Calabresi, MT Viscomi, CN Serhan, V Chiurchiù, M D'Amelio, NB Mercuri
Nat Commun, 2019-09-02;10(1):3945.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
Authors: A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies
Br. J. Cancer, 2019-08-16;121(7):556-566.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model
Authors: Y Nakamura, S Miyagawa, S Yoshida, S Sasawatari, T Toyofuku, K Toda, Y Sawa
Sci Rep, 2019-07-25;9(1):10840.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
Mediators Inflamm., 2019-07-10;2019(0):9086758.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis
Authors: H Lindahl, AO Guerreiro-, SK Bedri, M Linnerbaue, M Lindén, N Abdelmagid, K Tandre, C Hollins, L Irving, C Glover, C Jones, L Alfredsson, L Rönnblom, I Kockum, M Khademi, M Jagodic, T Olsson
J. Immunol., 2019-07-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress
Authors: DG Ogando, M Choi, R Shyam, S Li, JA Bonanno
Redox Biol, 2019-06-23;26(0):101260.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis
Authors: CC Pessoa, LC Reis, EM Ramos-Sanc, CM Orikaza, CC Plaza, EV de Castro, ACB Badaró, JUDS Yamamoto, V D'Almeida, H Goto, RA Mortara, F Real
PLoS Pathog., 2019-06-14;15(6):e1007834.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive decline
Authors: Y Ano, Y Yoshino, T Kutsukake, R Ohya, T Fukuda, K Uchida, A Takashima, H Nakayama
Aging (Albany NY), 2019-05-23;11(10):2949-2967.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain
Authors: GJ Song, MH Rahman, MK Jha, DP Gupta, SH Park, JH Kim, SH Lee, IK Lee, T Sim, YC Bae, WH Lee, K Suk
Front Pharmacol, 2019-05-20;10(0):543.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
Stem Cells, 2019-05-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice
Authors: AS Leal, SA Misek, EM Lisabeth, RR Neubig, KT Liby
Sci Rep, 2019-05-08;9(1):7072.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm
Authors: TA Nguyen, BRC Smith, KD Elgass, SJ Creed, S Cheung, MD Tate, GT Belz, IP Wicks, SL Masters, KC Pang
J. Immunol., 2019-05-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture
Authors: AM Giebel, S Hu, K Rajaram, R Finethy, E Toh, JA Brothwell, SG Morrison, RJ Suchland, BD Stein, J Coers, RP Morrison, DE Nelson
MBio, 2019-04-09;10(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Signal regulatory protein ? protects podocytes through promoting autophagic activity
Authors: L Li, Y Liu, S Li, Y Yang, C Zeng, W Rong, H Liang, M Zhang, X Zhu, K Kidder, Y Liu, Z Liu, K Zen
JCI Insight, 2019-03-19;5(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
Authors: J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen
Nat. Med., 2019-03-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells
Authors: M Kita, Y Ano, A Inoue, J Aoki
Sci Rep, 2019-02-28;9(1):3135.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe
Authors: PM Ryan, EH Stolte, LEE London, JM Wells, SL Long, SA Joyce, CGM Gahan, GF Fitzgerald, RP Ross, NM Caplice, C Stanton
BMC Microbiol., 2019-02-08;19(1):33.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation
Authors: Y Saeki, K Ishiyama, N Ishida, Y Tanaka, H Ohdan
Sci Rep, 2019-01-31;9(1):1022.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation
Authors: Y Ano, R Ohya, M Kita, Y Taniguchi, K Kondo
Molecules, 2019-01-28;24(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Vitamin D improves sunburns by increasing autophagy in M2 macrophages
Authors: LM Das, AM Binko, ZP Traylor, H Peng, KQ Lu
Autophagy, 2019-01-24;0(0):1-14.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
J. Immunol., 2019-01-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1
Authors: AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, AR Johnson, JJ Milner, MF Lim, JA Galanko, MA Beck, JE Bear, JD Rotty, L Bezavada, HS Smallwood, MA Puchowicz, J Liu, JW Locasale, DP Lee, BJ Bennett, ED Abel, JC Rathmell, L Makowski
J. Immunol., 2019-01-18;0(0):.
Species: Mouse
Sample Types: Whole Cells

MUC16 suppresses human and murine innate immune responses
Authors: M Felder, A Kapur, AL Rakhmilevi, X Qu, PM Sondel, SD Gillies, J Connor, MS Patankar
Gynecol. Oncol., 2019-01-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis
Authors: JD Jones, BP Sinder, D Paige, FN Soki, AJ Koh, S Thiele, Y Shiozawa, LC Hofbauer, S Daignault, H Roca, LK McCauley
Neoplasia, 2018-12-31;21(2):172-184.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

REV-ERB? Regulates TH17 Cell Development and Autoimmunity
Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
Cell Rep, 2018-12-26;25(13):3733-3749.e8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BCL6-Mediated Silencing of PD-1 Ligands in Germinal Center B Cells Maintains Follicular T Cell Population
Authors: C Peng, Q Hu, F Yang, H Zhang, F Li, C Huang
J. Immunol., 2018-12-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
Mol Brain, 2018-12-18;11(1):75.
Species: Mouse
Sample Types: Recombinant Protein
Applications: ELISA (Standard)

AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
Authors: G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud
Cell Rep, 2018-11-20;25(8):2163-2176.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage
Authors: Z Zuo, JX Shen, Y Pan, J Pu, YG Li, XH Shao, WP Wang
Cell. Physiol. Biochem., 2018-11-16;51(1):244-261.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
Authors: AM Falcão, D van Brugge, S Marques, M Meijer, S Jäkel, E Agirre, Samudyata, EM Floriddia, DP Vanichkina, C Ffrench-Co, A Williams, AO Guerreiro-, G Castelo-Br
Nat. Med., 2018-11-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells
Authors: J Falero-Per, YS Song, Y Zhao, L Teixeira, CM Sorenson, N Sheibani
PLoS ONE, 2018-10-29;13(10):e0206756.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms
Authors: F Zhang, O Ledue, M Jun, C Goulart, R Malley, YJ Lu
MBio, 2018-10-16;9(5):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus
Authors: A Sang, T Danhorn, JN Peterson, AL Rankin, BP O'Connor, SM Leach, RM Torres, R Pelanda
Nat Commun, 2018-09-28;9(1):3973.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners
Authors: C Farruggia, MB Kim, M Bae, Y Lee, TX Pham, Y Yang, MJ Han, YK Park, JY Lee
J. Nutr. Biochem., 2018-09-19;62(0):202-209.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
Authors: E Mobarak, L Håversen, M Manna, M Rutberg, M Levin, R Perkins, T Rog, I Vattulaine, J Borén
Sci Rep, 2018-09-11;8(1):13600.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Plectin protects podocytes from adriamycin-induced apoptosis and F-actin cytoskeletal disruption through the integrin ?6?4/FAK/p38 MAPK pathway
Authors: Y Ni, X Wang, X Yin, Y Li, X Liu, H Wang, X Liu, J Zhang, H Gao, B Shi, S Zhao
J. Cell. Mol. Med., 2018-09-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
Biol. Reprod., 2018-09-01;0(0):.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression
Authors: S Kim, MJ Lee, JY Choi, DH Park, HB Kwak, S Moon, JW Koh, HK Shin, JK Ryu, CS Park, JH Park, JH Kang
Cell. Physiol. Biochem., 2018-08-09;48(5):1829-1842.
Species: Mouse
Sample Types: Whole Cells
Applications: Stimulation

Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions
Authors: SK Varanasi, NK Rajasagi, U Jaggi, BT Rouse
Mucosal Immunol, 2018-08-07;0(0):.
Species: Mouse
Sample Types:

Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice
Authors: Y Yin, H Hao, Y Cheng, L Zang, J Liu, J Gao, J Xue, Z Xie, Q Zhang, W Han, Y Mu
Cell Death Dis, 2018-07-09;9(7):760.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting
Authors: DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi
EMBO Mol Med, 2018-07-01;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
Authors: YM Nusse, AK Savage, P Marangoni, AKM Rosendahl-, TA Landman, FJ de Sauvage, RM Locksley, OD Klein
Nature, 2018-06-27;559(7712):109-113.
Species: Mouse
Sample Types: Organoids
Applications: Bioassay

Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment.
Authors: A Martin, C Seignez, C Racoeur, N Isambert, Isambert N, N Mabrouk, Mabrouk N, A Scagliarin, Scagliarini A, S Reveneau, Reveneau S, L Arnould, Arnould L, A Bettaieb, JF Jeannin, Jeannin J, C Paul
Oncotarget, 2018-06-19;9(47):28364-28378.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Authors: Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi
Sci Rep, 2018-05-30;8(1):8414.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways
Authors: YX Jiang, YY Dai, YF Pan, XM Wu, Y Yang, K Bian, DD Zhang
Evid Based Complement Alternat Med, 2018-05-22;2018(0):6714282.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells
Authors: H Su, Z Zhang, Z Liu, B Peng, C Kong, H Wang, Z Zhang, Y Xu
J. Biol. Chem., 2018-05-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells
Authors: BJ Morrison, JC Steel, JC Morris
BMC Cancer, 2018-04-26;18(1):469.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Nonpyroptotic IFN-?-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo
Authors: JP Ingram, S Tursi, T Zhang, W Guo, C Yin, M A Wynosky-, J van der He, KQ Cai, M Yamamoto, BB Finlay, IE Brodsky, SI Grivenniko, Ç Tükel, S Balachandr
J. Immunol., 2018-04-13;0(0):.
Species: Mouse, Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

Loss of NF-?B1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner
Authors: LA O'Reilly, TL Putoczki, LA Mielke, JT Low, A Lin, A Preaudet, MJ Herold, K Yaprianto, L Tai, A Kueh, G Pacini, RL Ferrero, R Gugasyan, Y Hu, M Christie, S Wilcox, R Grumont, MDW Griffin, L O'Connor, GK Smyth, M Ernst, P Waring, S Gerondakis, A Strasser
Immunity, 2018-03-20;48(3):570-583.e8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tetrahydrocurcumin Enhances Islet Cell Function and Attenuates Apoptosis in Mouse Islets
Authors: SS Kim, HJ Jang, MY Oh, JH Lee, KS Kang
Transplant. Proc., 2018-03-16;50(9):2847-2853.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice
Authors: YW Yu, MX Li, ZY Zhang, H Yu
Int. J. Mol. Med., 2018-03-16;41(6):3577-3585.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Induced pluripotent stem cells-derived myeloid-derived suppressor cells regulate the CD8+ T cell response
Authors: D Joyce, M Fujino, M Morita, R Araki, J Fung, S Qian, L Lu, XK Li
Stem Cell Res, 2018-03-16;29(0):32-41.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation
Authors: Y Liu, X Liang, W Dong, Y Fang, J Lv, T Zhang, R Fiskesund, J Xie, J Liu, X Yin, X Jin, D Chen, K Tang, J Ma, H Zhang, J Yu, J Yan, H Liang, S Mo, F Cheng, Y Zhou, H Zhang, J Wang, J Li, Y Chen, B Cui, ZW Hu, X Cao, F Xiao-Feng, B Huang
Cancer Cell, 2018-03-12;33(3):480-494.e7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function
Authors: AS Chitre, MG Kattah, YY Rosli, M Pao, M Deswal, SG Deeks, PW Hunt, M Abdel-Mohs, LJ Montaner, CC Kim, A Ma, M Somsouk, JM McCune
PLoS Pathog., 2018-03-05;14(3):e1006806.
Species: Mouse
Sample Types: Organoids
Applications: Bioassay

RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
Authors: C Sun, SY Chen
J. Immunol., 2018-03-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist
Authors: K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park, JH Ju
PLoS ONE, 2018-02-26;13(2):e0193086.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
Mol Metab, 2018-02-23;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis
Authors: M Chen, J Zhao, IH Ali, S Marry, J Augustine, M Bhuckory, A Lynch, A Kissenpfen, H Xu
Am. J. Pathol., 2018-02-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
Authors: CES Guedes, BRS Dias, ALOA Petersen, KP Cruz, NJ Almeida, DR Andrade, JPB Menezes, VM Borges, PST Veras
Mem. Inst. Oswaldo Cruz, 2018-02-05;113(4):e170345.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Collagen-derived peptides modulate CD4T-cell differentiation and suppress allergic responses in mice
Authors: A Nishikimi, YI Koyama, S Ishihara, S Kobayashi, C Tometsuka, M Kusubata, K Kuwaba, O Hayashida, S Hattori, K Katagiri
Immun Inflamm Dis, 2018-02-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Circular RNAs as novel regulators of ?-cell functions in normal and disease conditions
Authors: L Stoll, J Sobel, A Rodriguez-, C Guay, K Lee, MT Venø, J Kjems, DR Laybutt, R Regazzi
Mol Metab, 2018-01-31;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation
Authors: E Burger, A Araujo, A López-Ygle, MW Rajala, L Geng, B Levine, LV Hooper, E Burstein, F Yarovinsky
Cell Host Microbe, 2018-01-18;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Stimulation

High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
Authors: A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai
Front Immunol, 2018-01-18;9(0):22.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

PGC-1? ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism
Authors: L Zhang, J Liu, F Zhou, W Wang, N Chen
Mol Med Rep, 2018-01-16;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PEDF Expression Affects the Oxidative and Inflammatory State of Choroidal Endothelial Cells
Authors: M Farnoodian, CM Sorenson, N Sheibani
Am. J. Physiol., Cell Physiol., 2018-01-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
Neurobiol. Dis., 2018-01-09;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells
Authors: P Bhat, AS Bergot, N Waterhouse, IH Frazer
Oncotarget, 2017-12-14;9(5):6015-6027.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
Authors: H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita
EBioMedicine, 2017-12-07;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
Authors: R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton
Cardiovasc Diabetol, 2017-11-06;16(1):143.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy
Authors: SA Samant, A Kanwal, VB Pillai, R Bao, MP Gupta
Sci Rep, 2017-09-19;7(1):11877.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid
Authors: CA Sorgi, S Zarini, SA Martin, RL Sanchez, RF Scandiuzzi, MA Gijón, C Guijas, N Flamand, RC Murphy, LH Faccioli
Sci Rep, 2017-09-08;7(1):10981.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interleukin 4 receptor-targeted pro-apoptotic peptide blocks tumor growth and metastasis by enhancing anti-tumor immunity
Authors: SMP Vadevoo, JE Kim, GR Gunassekar, HK Jung, L Chi, DE Kim, SH Lee, SH Im, B Lee
Mol. Cancer Ther., 2017-09-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted
Authors: V Vaithiling, MDM Evans, DM Lewy, PA Bean, S Bal, BE Tuch
Sci Rep, 2017-08-30;7(1):10059.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B
Authors: J Braverman, SA Stanley
J. Immunol., 2017-07-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation
Authors: G Nagalingam, CG Vinuesa, WJ Britton, BM Saunders
J. Immunol., 2017-07-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles
Authors: C Foltz, A Napolitano, R Khan, B Clough, EM Hirst, EM Frickel
Sci Rep, 2017-07-12;7(1):5209.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis
Authors: X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang
Sci Rep, 2017-07-11;7(1):5107.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pancreatic ?-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)
Authors: DA Cunha, M Cito, FA Grieco, C Cosentino, T Danilova, L Ladriere, M Lindahl, A Domanskyi, M Bugliani, P Marchetti, DL Eizirik, M Cnop
J. Biol. Chem., 2017-07-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model
Authors: W Zhang, DG Ogando, ET Kim, MJ Choi, H Li, JM Tenessen, JA Bonanno
Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3723-3731.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD4(+)CD8?(+) double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin
Authors: NH Overgaard, JL Cruz, JA Bridge, HJ Nel, IH Frazer, NL La Gruta, A Blumenthal, RJ Steptoe, JW Wells
J. Leukoc. Biol., 2017-06-21;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The inhibition of NLRP3 signaling attenuates liver injury in an ?-galactosylceramide-induced hepatitis model
Authors: A Kanbe, H Ito, Y Omori, A Hara, M Seishima
Biochem. Biophys. Res. Commun., 2017-06-14;0(0):.
Applications: ELISA (Standard)

The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells
Authors: S Iwata, Y Mikami, HW Sun, SR Brooks, D Jankovic, K Hirahara, A Onodera, HY Shih, T Kawabe, K Jiang, T Nakayama, A Sher, JJ O'Shea, FP Davis, Y Kanno
Immunity, 2017-06-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon-? derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
Authors: P Bhat, G Leggatt, N Waterhouse, IH Frazer
Cell Death Dis, 2017-06-01;8(6):e2836.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
Authors: L Quinti, S Dayalan Na, U Träger, X Chen, K Kegel-Glea, D Llères, C Connolly, V Chopra, C Low, S Moniot, E Sapp, AR Tousley, P Vodicka, MJ Van Kanega, LS Kaltenbach, LA Crawford, M Fuszard, M Higgins, JRC Miller, RE Farmer, V Potluri, S Samajdar, L Meisel, N Zhang, A Snyder, R Stein, SM Hersch, LM Ellerby, E Weerapana, MA Schwarzsch, C Steegborn, BR Leavitt, A Degterev, SJ Tabrizi, DC Lo, M DiFiglia, LM Thompson, AT Dinkova-Ko, AG Kazantsev
Proc. Natl. Acad. Sci. U.S.A., 2017-05-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis
Authors: MG Ledesma-Co, N Adán, G Ortiz, M Solís-Guti, F López-Barr, G Martínez d, C Clapp
Arthritis Res. Ther., 2017-05-15;19(1):93.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

A Rab20-Dependent Membrane Trafficking Pathway Controls M.�tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity
Authors: L Schnettger, A Rodgers, U Repnik, RP Lai, G Pei, M Verdoes, RJ Wilkinson, DB Young, MG Gutierrez
Cell Host Microbe, 2017-05-10;21(5):619-628.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

STAT3 promotes IFN?/TNF?-induced muscle wasting in an NF-?B-dependent and IL-6-independent manner
Authors: JF Ma, BJ Sanchez, DT Hall, AK Tremblay, S Di Marco, IE Gallouzi
EMBO Mol Med, 2017-05-01;0(0):.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage
Authors: B Jee, P Sharma, K Katoch, B Joshi, SK Awasthi
Braz J Infect Dis, 2017-04-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD11b regulates antibody class switching via induction of AID
Authors: S Park, H Sim, HI Kim, D Jeong, G Wu, SY Cho, YS Lee, HJ Kwon, K Lee
Mol. Immunol., 2017-04-11;87(0):47-59.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Microglia activation is essential for BMP7-mediated retinal reactive gliosis
Authors: S Dharmaraja, DL Fisk, CM Sorenson, N Sheibani, TL Belecky-Ad
J Neuroinflammation, 2017-04-05;14(1):76.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
Authors: DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh
Nat Commun, 2017-04-04;8(0):14919.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
Authors: AJ Morales, JA Carrero, PJ Hung, AT Tubbs, JM Andrews, BT Edelson, B Calderon, CL Innes, RS Paules, JE Payton, BP Sleckman
Elife, 2017-03-31;6(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk
Authors: V Piccolo, A Curina, M Genua, S Ghisletti, M Simonatto, A Sabò, B Amati, R Ostuni, G Natoli
Nat. Immunol, 2017-03-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
Authors: R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, YK Young, YK Im, T Pawson, AE Koromilas, WJ Muller, KK Mann, CL Kleinman, J Ursini-Sie
Nat Commun, 2017-03-09;8(0):14638.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages
Authors: DC Cockrell, CM Long, SJ Robertson, JG Shannon, HE Miller, L Myers, CL Larson, T Starr, PA Beare, RA Heinzen
PLoS ONE, 2017-03-09;12(3):e0173528.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-27a promotes podocyte injury via PPAR?-mediated ?-catenin activation in diabetic nephropathy
Authors: Z Zhou, J Wan, X Hou, J Geng, X Li, X Bai
Cell Death Dis, 2017-03-09;8(3):e2658.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
J. Nutr. Biochem, 2017-03-06;44(0):11-21.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
J. Allergy Clin. Immunol, 2017-03-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Characterisation of iunH gene knockout strain from Mycobacterium tuberculosis
Authors: AD Villela, VD Rodrigues, AF Pinto, PL Wink, ZA Sánchez-Qu, GO Petersen, MM Campos, LA Basso, DS Santos
Mem. Inst. Oswaldo Cruz, 2017-03-01;112(3):203-208.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Metabolic origins of spatial organization in the tumor microenvironment
Authors: C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier
Proc. Natl. Acad. Sci. U.S.A, 2017-02-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
Cell Death Discov, 2017-02-27;3(0):16097.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
Authors: J Lau, J Cheung, A Navarro, S Lianoglou, B Haley, K Totpal, L Sanders, H Koeppen, P Caplazi, J McBride, H Chiu, R Hong, J Grogan, V Javinal, R Yauch, B Irving, M Belvin, I Mellman, JM Kim, M Schmidt
Nat Commun, 2017-02-21;8(0):14572.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Bioassay

PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
Authors: S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen
Sci Rep, 2017-02-17;7(0):42846.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4(+) memory T cells
Authors: BA Szilagyi, J Triebus, C Kressler, M de Almeida, S Tierling, P Durek, M Mardahl, A Szilagyi, S Floess, J Huehn, U Syrbe, J Walter, JK Polansky, A Hamann
Mucosal Immunol, 2017-02-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Astrocytic orosomucoid-2 modulates microglial activation and neuroinflammation
Authors: M Jo, JH Kim, G Song, M Seo, E Mi Hwang, K Suk
J. Neurosci, 2017-02-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pathogen-mediated manipulation of arthropod microbiota to promote infection
Authors: NM Abraham, L Liu, BL Jutras, AK Yadav, S Narasimhan, V Gopalakris, JM Ansari, KK Jefferson, F Cava, C Jacobs-Wag, E Fikrig
Proc. Natl. Acad. Sci. U.S.A, 2017-01-17;114(5):E781-E790.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
Authors: MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat
Proc. Natl. Acad. Sci. U.S.A, 2017-01-09;114(4):E524-E533.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
Sci Rep, 2016-12-08;6(0):38387.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Context-Specific and Immune Cell-Dependent Antitumor Activities of ?1-Antitrypsin
Authors: Ofer Guttman
Front Immunol, 2016-12-07;7(0):559.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma
Authors: A K Kosmides
Biomaterials, 2016-12-02;118(0):16-26.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
Sci Rep, 2016-12-01;6(0):37977.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Application of genetically engineered Salmonella typhimurium for interferon-gamma-induced therapy against melanoma
Authors: Byeong Mo Kim
Eur. J. Cancer, 2016-11-22;70(0):48-61.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Epobis is a Nonerythropoietic and Neuroprotective Agonist of the Erythropoietin Receptor with Anti-Inflammatory and Memory Enhancing Effects
Authors: Oksana Dmytriyeva
Mediators Inflamm, 2016-11-21;2016(0):1346390.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Individual and interactive sex-specific effects of acute restraint and systemic IFN-? treatment on neurochemistry
Authors: Shawn Hayley
Neurochem. Int., 2016-11-19;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
Sci Rep, 2016-11-15;6(0):37211.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Macrophages form functional vascular mimicry channels in vivo
Sci Rep, 2016-11-11;6(0):36659.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy
J. Immunol., 2016-11-09;197(12):4750-4761.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells
Authors: W Dawicki, C Li, J Town, X Zhang, JR Gordon
J. Allergy Clin. Immunol., 2016-10-26;139(5):1608-1620.e3.
Species: Mouse
Sample Types: Serum
Applications: ELISA (Standard)

Proteasome Activators, PA28? and PA28?, Govern Development of Microvascular Injury in Diabetic Nephropathy and Retinopathy
Authors: Ali Mahmoudpou
Int J Nephrol, 2016-10-18;2016(0):3846573.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma
Cancer Res, 2016-09-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
J Biol Chem, 2016-09-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
JCI Insight, 2016-09-08;1(14):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mechanisms Underlying Interferon-?-Induced Priming of Microglial Reactive Oxygen Species Production
PLoS ONE, 2016-09-06;11(9):e0162497.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei
PLoS Negl Trop Dis, 2016-08-25;10(8):e0004907.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments
Authors: Haiyan Peng
J. Neuroimmunol, 2016-08-05;299(0):35-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NADPH oxidases are essential for macrophage differentiation
J Biol Chem, 2016-08-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development
Authors: Niels Olsen Saraiva Camara
Immun Inflamm Dis, 2016-07-21;4(3):300-14.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis
J Immunol, 2016-07-18;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Circ Res, 2016-07-14;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

G2A Signaling Dampens Colitic Inflammation via Production of IFN-?
J Immunol, 2016-07-08;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages
Authors: L R Batista-Si
Sci Rep, 2016-06-10;6(0):27632.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
Nat Commun, 2016-05-23;7(0):11624.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
J. Biol. Chem., 2016-05-23;291(30):15830-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
Nat Med, 2016-05-09;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Platelets Guide Leukocytes to Their Sites of Extravasation
PLoS Biol, 2016-05-06;14(5):e1002459.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization
J Immunol, 2016-05-04;196(11):4536-43.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
Authors: P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi
Oncogene, 2016-04-25;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis
Authors: C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto
J Immunol, 2016-04-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
Authors: Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, Smith I, Tothova Z, Wilen C, Orchard R, Virgin H, Listgarten J, Root D
Nat Biotechnol, 2016-01-18;34(2):184-91.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia.
Authors: Somintara S, Leardkamolkarn V, Suttiarporn P, Mahatheeranont S
PLoS ONE, 2016-01-11;11(1):e0146869.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
J Immunol, 2015-09-21;195(9):4415-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response.
Authors: Cohen H, Ward A, Hamidzadeh K, Ravid K, Mosser D
J Immunol, 2015-09-09;195(8):3828-37.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
J Immunol, 2015-09-09;195(8):3531-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activated Brain Endothelial Cells Cross-Present Malaria Antigen.
Authors: Howland S, Poh C, Renia L
PLoS Pathog, 2015-06-05;11(6):e1004963.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
Authors: Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H
Eur J Immunol, 2015-05-28;45(9):2494-503.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice.
Authors: Alam I, Gray A, Acton D, Gerard-O'Riley R, Reilly A, Econs M
J Bone Miner Res, 2015-05-14;30(11):2005-13.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Dynamics of Circulating gammadelta T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
Authors: Beck B, Kim H, O'Brien R, Jadus M, Gillespie G, Cloud G, Hoa N, Langford C, Lopez R, Harkins L, Lamb L
PLoS ONE, 2015-05-08;10(5):e0122387.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
J Biol Chem, 2015-03-26;290(19):12394-402.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis.
Authors: Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E
PLoS ONE, 2015-03-20;10(3):e0120327.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells.
Authors: Guay C, Menoud V, Rome S, Regazzi R
Cell Commun Signal, 2015-03-19;13(0):17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Authors: Jha A, Huang S, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, Chmielewski K, Stewart K, Ashall J, Everts B, Pearce E, Driggers E, Artyomov M
Immunity, 2015-03-17;42(3):419-30.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences.
Authors: Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D
J Invest Dermatol, 2015-03-04;135(7):1771-80.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
Authors: Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D
EMBO Mol Med, 2015-03-01;7(3):240-58.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
Authors: Sag D, Cekic C, Wu R, Linden J, Hedrick C
Nat Commun, 2015-02-27;6(0):6354.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
Authors: Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, Fung H, Albrecht S, Alexandropoulos K, McCauley D, Chook Y, Kuhlmann T, Kidd G, Shacham S, Casaccia P
Nat Neurosci, 2015-02-23;18(4):511-20.
Species: Mouse
Sample Types: In Vivo

Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.
Authors: Goodsmith N, Guo X, Vandal O, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P, Schnappinger D, Ehrt S
PLoS Pathog, 2015-02-06;11(2):e1004645.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.
Authors: Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, Ozato K, Natoli G
Genes Dev, 2015-01-30;29(4):394-408.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.
Authors: Ma F, Li B, Liu S, Iyer S, Yu Y, Wu A, Cheng G
J Immunol, 2015-01-21;194(4):1545-54.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
Authors: Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M
Autophagy, 2015-01-01;11(2):271-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Protective role for caspase-11 during acute experimental murine colitis.
Authors: Oficjalska K, Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, Corr S, Kay E, O'Neill L, Mills K, Creagh E
J Immunol, 2014-12-29;194(3):1252-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells.
Authors: Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, Uchino M, Ando Y, Nagafuchi S, Nishimura Y, Senju S
PLoS ONE, 2014-12-18;9(12):e115198.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8.
Authors: Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S
Cancer Res, 2014-11-20;75(2):330-43.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
Authors: Dohi, Kenji, Kraemer, Brian C, Erickson, Michelle, McMillan, Pamela J, Kovac, Andrej, Flachbartova, Zuzana, Hansen, Kim M, Shah, Gul N, Sheibani, Nader, Salameh, Therese, Banks, William
PLoS ONE, 2014-09-24;9(9):e108034.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
Elife, 2014-09-16;3(0):e02809.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages.
Authors: Mulye M, Bechill M, Grose W, Ferreira V, Lafontaine E, Wooten R
PLoS Negl Trop Dis, 2014-08-21;8(8):e2988.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Peroxisome proliferator-activated receptor alpha protects capillary pericytes in the retina.
Authors: Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins A, Keech A, Humphries K, Gu X, Elliott M, Xia X, Ma J
Am J Pathol, 2014-08-07;184(10):2709-20.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
J Immunol, 2014-08-04;193(6):3036-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Control of intracellular Francisella tularensis by different cell types and the role of nitric oxide.
Authors: Newstead S, Gates A, Hartley M, Rowland C, Williamson E, Lukaszewski R
J Immunol Res, 2014-07-21;2014(0):694717.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Synergistic up-regulation of CXCL10 by virus and IFN gamma in human airway epithelial cells.
Authors: Oslund K, Zhou X, Lee B, Zhu L, Duong T, Shih R, Baumgarth N, Hung L, Wu R, Chen Y
PLoS ONE, 2014-07-17;9(7):e100978.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
Nat Commun, 2014-07-14;5(0):4436.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes.
Authors: Castro C, Barcala Tabarrozzi A, Winnewisser J, Gimeno M, Antunica Noguerol M, Liberman A, Paz D, Dewey R, Perone M
Clin Exp Immunol, 2014-07-01;177(1):149-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.
Authors: Chen D, Goswami C, Burnett R, Anjanappa M, Bhat-Nakshatri P, Muller W, Nakshatri H
Cancer Res, 2014-06-30;74(16):4270-81.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-gamma.
Authors: Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, Kalkhoven E, Nieuwenhuis E, Clevers H
J Exp Med, 2014-06-30;211(7):1393-405.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.
Authors: Stoolman J, Duncker P, Huber A, Segal B
J Immunol, 2014-06-13;193(2):564-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

USP18 is crucial for IFN-gamma-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity.
Authors: Hong B, Li H, Lu Y, Zhang M, Zheng Y, Qian J, Yi Q
Mol Cancer, 2014-05-31;13(0):132.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
Autophagy, 2014-05-14;10(7):1301-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells.
Authors: Hirosue S, Vokali E, Raghavan V, Rincon-Restrepo M, Lund A, Corthesy-Henrioud P, Capotosti F, Halin Winter C, Hugues S, Swartz M
J Immunol, 2014-05-02;192(11):5002-11.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Intramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan.
Authors: Falconer J, Lowes K, Furmanski A, Dyson J, Ng W, Robinson J
Immunology, 2014-05-01;142(1):101-110.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function.
Authors: Bhatt S, Qin J, Bennett C, Qian S, Fung J, Hamilton T, Lu L
J Immunol, 2014-04-30;192(11):5098-108.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.
Authors: Cebrian C, Zucca F, Mauri P, Steinbeck J, Studer L, Scherzer C, Kanter E, Budhu S, Mandelbaum J, Vonsattel J, Zecca L, Loike J, Sulzer D
Nat Commun, 2014-04-16;5(0):3633.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
Nature, 2014-04-13;509(7499):235-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The primary cilium influences interleukin-1beta-induced NFkappaB signalling by regulating IKK activity.
Authors: Wann A, Chapple J, Knight M
Cell Signal, 2014-04-12;26(8):1735-42.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.
Authors: Mboko W, Mounce B, Emmer J, Darrah E, Patel S, Tarakanova V
J Virol, 2014-04-09;88(12):6993-7004.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
J Immunol, 2014-03-21;192(8):3569-81.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: ELISA (Standard)

Improved repair of dermal wounds in mice lacking microRNA-155.
Authors: van Solingen C, Araldi E, Chamorro-Jorganes A, Fernandez-Hernando C, Suarez Y
J Cell Mol Med, 2014-03-17;18(6):1104-12.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
Authors: Sriskantharajah S, Guckel E, Tsakiri N, Kierdorf K, Brender C, Ben-Addi A, Veldhoen M, Tsichlis P, Stockinger B, O'Garra A, Prinz M, Kollias G, Ley S
J Immunol, 2014-03-17;192(8):3518-29.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-13 orchestrates resolution of chronic intestinal inflammation via phosphorylation of glycogen synthase kinase-3beta.
Authors: Fichtner-Feigl S, Kesselring R, Martin M, Obermeier F, Ruemmele P, Kitani A, Brunner S, Haimerl M, Geissler E, Strober W, Schlitt H
J Immunol, 2014-03-14;192(8):3969-80.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Collective nitric oxide production provides tissue-wide immunity during Leishmania infection.
Authors: Olekhnovitch R, Ryffel B, Muller A, Bousso P
J Clin Invest, 2014-03-10;124(4):1711-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4.
Authors: Yu C, Nguyen T, Irvine K, Sweet M, Frazer I, Blumenthal A
Eur J Immunol, 2014-03-07;44(5):1480-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI.
Authors: Al Faraj, Achraf, Sultana Shaik, Asma, Pureza, Mary Ang, Alnafea, Mohammad, Halwani, Rabih
PLoS ONE, 2014-03-05;9(3):e90829.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
BMC Cancer, 2014-02-20;14(0):113.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
Authors: Tatano Y, Shimizu T, Tomioka H
Sci Rep, 2014-02-20;4(0):4146.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge.
Authors: Bouwer A, Saunderson S, Caldwell F, Damani T, Pelham S, Dunn A, Jack R, Stoitzner P, McLellan A
J Immunol, 2014-01-29;192(5):2514-21.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endothelial cell-derived chemerin promotes dendritic cell transmigration.
Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
J Immunol, 2014-01-27;192(5):2366-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
Authors: Sidney L, Kirkham G, Buttery L
Stem Cells Dev, 2014-01-23;23(6):605-17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironment.
Authors: Ling W, Zhang J, Yuan Z, Ren G, Zhang L, Chen X, Rabson A, Roberts A, Wang Y, Shi Y
Cancer Res, 2014-01-22;74(5):1576-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages.
Authors: Alamuru N, Behera S, Butchar J, Tridandapani S, Kaimal Suraj S, Babu P, Hasnain S, Ehtesham N, Parsa K
J Leukoc Biol, 2014-01-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation.
Authors: Veremeyko, Tatyana, Siddiqui, Shafiudd, Sotnikov, Ilya, Yung, Amanda, Ponomarev, Eugene D
PLoS ONE, 2013-12-16;8(12):e81774.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
J Immunol, 2013-12-09;192(1):59-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TGF-beta promotes immune responses in the presence of mesenchymal stem cells.
Authors: Xu C, Yu P, Han X, DU L, Gan J, Wang Y, Shi Y
J Immunol, 2013-11-29;192(1):103-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
Mucosal Immunol, 2013-11-13;7(4):818-28.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro.
Authors: Liu, Jia, Jiang, Min, Ma, Zhiyong, Dietze, Kirsten, Zelinskyy, Gennadiy, Yang, Donglian, Dittmer, Ulf, Schlaak, Joerg F, Roggendorf, Michael, Lu, Mengji
J Immunol, 2013-11-13;191(12):6178-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The exonuclease Trex1 restrains macrophage proinflammatory activation.
Authors: Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst A, Lloberas J, Celada A
J Immunol, 2013-11-11;191(12):6128-35.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation.
Authors: Keil E, Finkenstadt D, Wufka C, Trilling M, Liebfried P, Strobl B, Muller M, Pfeffer K
Blood, 2013-10-29;123(4):520-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue.
Authors: Jiang E, Perrard X, Yang D, Khan I, Perrard J, Smith C, Ballantyne C, Wu H
Arterioscler Thromb Vasc Biol, 2013-10-24;34(1):34-43.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An antioxidant role for catecholate siderophores in Salmonella.
Authors: Achard, Maud E S, Chen, Kaiwen W, Sweet, Matthew, Watts, Rebecca, Schroder, Kate, Schembri, Mark A, McEwan, Alastair
Biochem J, 2013-09-15;454(3):543-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
Authors: Steelman A, Smith R, Welsh C, Li J
J Biol Chem, 2013-07-08;288(33):23776-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/beta-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria.
Authors: Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, He W, Yang J, Dai C
J Biol Chem, 2013-06-26;288(32):23368-79.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.
Authors: Selleck E, Fentress S, Beatty W, Degrandi D, Pfeffer K, Virgin H, Macmicking J, Sibley L
PLoS Pathog, 2013-04-25;9(4):e1003320.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation and migratory role of P-selectin ligands during intestinal inflammation.
Authors: Hoffmann U, Pink M, Lauer U, Heimesaat M, Winsauer C, Kruglov A, Schlawe K, Leichsenring C, Liesenfeld O, Hamann A, Syrbe U
PLoS ONE, 2013-04-22;8(4):e62055.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma.
Authors: Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S
PLoS ONE, 2013-04-17;8(4):e61446.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.
Authors: Gaffal E, Cron M, Glodde N, Bald T, Kuner R, Zimmer A, Lutz B, Tuting T
J Immunol, 2013-04-12;190(10):4929-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD43-mediated IFN-gamma production by CD8+ T cells promotes abdominal aortic aneurysm in mice.
Authors: Zhou H, Yan H, Cannon J, Springer L, Green J, Pham C
J Immunol, 2013-04-12;190(10):5078-85.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
J Biol Chem, 2013-03-04;288(18):12699-711.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-beta signaling pathways.
Authors: Park S, Dimaio T, Liu W, Wang S, Sorenson C, Sheibani N
J Cell Sci, 2013-02-15;126(0):1392-405.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes.
Authors: Moran C, Jose R, Moxon J, Roomberg A, Norman P, Rush C, Korner H, Golledge J
Arterioscler Thromb Vasc Biol, 2013-02-07;33(4):814-21.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Association of beta-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-beta1.
Authors: Tian X, Zhang J, Tan T, Lyons J, Zhao H, Niu B, Lee S, Tsatralis T, Zhao Y, Wang Y, Cao Q, Wang C, Wang Y, Lee V, Kahn M, Zheng G, Harris D
J Cell Sci, 2012-11-30;126(0):67-76.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity.
Authors: Jeyanathan M, Damjanovic D, Shaler C, Lai R, Wortzman M, Yin C, Zganiacz A, Lichty B, Xing Z
Mucosal Immunol, 2012-11-07;6(3):612-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner.
Authors: Kim H, Chung D
Mucosal Immunol, 2012-08-15;6(2):347-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ATP release and autocrine signaling through P2X4 receptors regulate gammadelta T cell activation.
Authors: Manohar M, Hirsh M, Chen Y, Woehrle T, Karande A, Junger W
J Leukoc Biol, 2012-06-29;92(4):787-94.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of innate CD8+ T-cell activation mediated by cytokines.
Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon gamma inhibits adipogenesis in vitro and prevents marrow fat infiltration in oophorectomized mice.
Authors: Vidal C, Bermeo S, Li W, Huang D, Kremer R, Duque G
Stem Cells, 2012-05-01;30(5):1042-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
Am. J. Pathol., 2011-10-26;180(1):365-74.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii.
J. Immunol., 2011-05-23;187(1):350-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue.
Authors: Nicholls HT, Kowalski G, Kennedy DJ
Diabetes, 2011-03-04;60(4):1100-10.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15R alpha.
Authors: Sato N, Sabzevari H, Fu S, Ju W, Petrus MN, Bamford RN, Waldmann TA, Tagaya Y
Blood, 2011-02-08;117(15):4032-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss.
Authors: Liang S, Krauss JL, Domon H, McIntosh ML, Hosur KB, Qu H, Li F, Tzekou A, Lambris JD, Hajishengallis G
J. Immunol., 2010-12-13;186(2):869-77.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation.
Authors: Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD
J. Immunol., 2010-09-20;185(8):4912-20.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
Authors: Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE
J. Immunol., 2010-09-10;185(7):4354-62.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
Authors: Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G, Blankenstein T, Hammerling GJ, Arnold B, Schuler T
Eur. J. Immunol., 2010-09-01;40(9):2391-400.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
J. Immunol., 2010-07-21;185(4):2044-50.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

TGFbeta2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion.
Authors: Craig EA, Craig E, Austin AF, Austin A, Vaillancourt RR, Vaillancourt R, Barnett JV, Camenisch TD, Camenisch T
Exp Cell Res, 2010-07-13;316(20):3397-405.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes.
Authors: Wu J, Wrathall JR, Schachner M
Glia, 2010-02-01;58(3):315-28.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
Authors: Strissel KJ, DeFuria J, Shaul ME, Bennett G, Greenberg AS, Obin MS
Obesity (Silver Spring), 2010-01-28;18(10):1918-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
J. Immunol., 2009-10-19;183(10):6135-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
Mucosal Immunol, 2009-10-07;3(1):40-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.
Authors: Ilarregui JM, Croci DO, Bianco GA, Toscano MA, Salatino M, Vermeulen ME, Geffner JR, Rabinovich GA
Nat. Immunol., 2009-08-09;10(9):981-91.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
J. Immunol., 2009-07-27;183(4):2642-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
Nature, 2009-06-03;460(7252):269-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9.
Species: Mouse
Sample Types: In Vivo, N/A
Applications: ELISA (Standard), In Vivo

ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
Microbes Infect., 2009-03-13;11(4):524-30.
Applications: ELISA (Standard)

Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.
Authors: Cui W, Joshi NS, Jiang A, Kaech SM
Vaccine, 2009-02-06;27(15):2177-87.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells.
Authors: Smith KE, Fritzell S, Badn W, Eberstal S, Janelidze S, Visse E, Darabi A, Siesjo P
Int. J. Cancer, 2009-02-01;124(3):630-7.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.
Authors: Bhowmick S, Mazumdar T, Ali N
Infect. Immun., 2009-01-21;77(4):1514-23.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
J. Exp. Med., 2009-01-12;206(1):69-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma down-regulates Secretoglobin 3A1 gene expression.
Authors: Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, Takami M, Donnelly RP, Itabe H, Yamamoto M, Kimura S, Kamijo R
Biochem. Biophys. Res. Commun., 2009-01-09;379(4):964-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells.
Authors: Liu T, Huang Y, Likhotvorik RI, Keshvara L, Hoyt DG
Am. J. Physiol., Cell Physiol., 2008-07-23;295(3):C819-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.
Authors: Nairz M, Fritsche G, Brunner P, Talasz H, Hantke K, Weiss G
Eur. J. Immunol., 2008-07-01;38(7):1923-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
Immunology, 2008-04-03;125(2):272-9.
Applications: ELISA (Standard)

IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus.
Authors: Lee YM, Miyahara N, Takeda K, Prpich J, Oh A, Balhorn A, Joetham A, Gelfand EW, Dakhama A
Am. J. Respir. Crit. Care Med., 2007-10-25;177(2):208-18.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Maternal immune activation alters fetal brain development through interleukin-6.
Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
J. Neurosci., 2007-10-03;27(40):10695-702.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
Authors: Schell JB, Crane CA, Smith MF, Roberts MR
J. Neuroimmunol., 2007-08-15;189(1):75-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007-05-15;245(2):70-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration.
Authors: Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, Raddassi K, Bronson RT, Khoury SJ
Am. J. Pathol., 2007-05-01;170(5):1695-712.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
J. Immunol., 2006-12-15;177(12):8650-7.
Applications: ELISA (Standard)

Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
J. Immunol., 2006-09-01;177(5):3388-97.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.
Authors: Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M
Proc. Natl. Acad. Sci. U.S.A., 2006-07-24;103(31):11784-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis.
Authors: Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M
J. Clin. Invest., 2006-03-23;116(4):905-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
J Ethnopharmacol, 2006-03-10;106(3):418-24.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Differential Growth of IFN-beta-Engineered Tumor Cells in Nude and IFN Receptor-Null Mice.
Authors: Zhang F, Lee J, Wang D, Dong Z
J. Interferon Cytokine Res., 2006-02-01;26(2):108-18.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
Mol. Cell. Neurosci., 2005-11-16;31(1):149-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
J. Virol., 2005-10-01;79(20):12828-39.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sequential ELISA to profile multiple cytokines from small volumes.
Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
J. Immunol. Methods, 2005-07-01;302(1):172-81.
Applications: ELISA (Standard)

Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma.
Authors: Kamath AT, Sheasby CE, Tough DF
J. Immunol., 2005-01-15;174(2):767-76.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Bioassay

Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression.
Authors: Murphey ED, Herndon DN, Sherwood ER
Infect. Immun., 2004-12-01;72(12):6892-901.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
Authors: Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT
J. Biol. Chem., 2004-10-13;279(52):54405-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-22 increases the innate immunity of tissues.
Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity, 2004-08-01;21(2):241-54.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
J. Immunol., 2004-06-15;172(12):7408-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.
Authors: Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB
J. Immunol., 2004-05-15;172(10):6476-81.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16.
Authors: Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW
J. Immunol., 2004-03-15;172(6):3678-85.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody.
Authors: Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G
J. Immunol., 2003-12-15;171(12):6466-77.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
J. Immunol., 2003-11-15;171(10):5107-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor.
Authors: Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, Housseau F
J. Exp. Med., 2003-07-07;198(1):31-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts.
Authors: Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM
Am. J. Pathol., 2003-05-01;162(5):1475-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.
Authors: Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y
J. Immunol., 2002-05-01;168(9):4764-71.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo