It was another exciting year for science at the 2017 International Society for Stem Cell Research (ISSCR) Meeting! Playing on the meeting theme, ‘Science Insightfully Delivered’, there was a palatable emphasis in presentation topics focusing on translating stem cell research to the clinic. The translational aspect was complemented by some great posters and lectures highlighting cutting-edge science being done by the stem cell research community. Here are a couple of scientific hits and themes that we identified from the meeting.
Blogs for June 2017
Quantikine ELISA Validation: Making the Industry Gold Standard
Thursday, June 22, 2017 - 13:28
When selecting an ELISA kit, different users often have different criteria in making their choice, whether it is sensitivity, sample types, or ease-of-use. One universal criterion is that an ELISA must work the first time and every time you use it. R&D Systems has developed our
Quantikine® ELISAs from raw materials that we make in-house, giving us unparalleled control over critical elements that affect your results and creating consistency of results over long periods of time. Whether you are breaking new ground or building on the work of others, you can trust that the results will be reproducible tomorrow, next week, and...
All Pluripotent Stem Cells Are Not Created Equal
Monday, June 19, 2017 - 13:08
The generation of induced pluripotent stem (iPS) cells has become a routine task in many laboratories. Across the globe, scientists are using published or commercial reprogramming methods to create iPS cells that further their studies in regenerative medicine, disease modeling, and drug discovery. As we noted in a previous blog post, questions about experimental reproducibility are percolating to the top of major issues that the stem cell field must address in order to confidently guide basic...
Bio-Techne Go Everywhere Travel Grant – May Recipient Selected!
Monday, June 12, 2017 - 10:47
May 2017 Go Everywhere with Bio-Techne Travel Grant Awarded to PhD Candidate from Griffith Institute for Drug Discovery!
Bio-Techne launched its Go Everywhere Travel Grant Program which awards $1000 USD (or equivalent) to 1 researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration.
The recipient of the May 2017 grant is Hannah Leeson, a PhD Candidate at Griffith University in Nathan, Australia!
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Butyrophilins, Cancer, and Inflammation
Tuesday, June 6, 2017 - 07:06
T cell activation requires two signals: 1) recognition of the antigenic peptide/major histocompatibility complex (MHC) by the T cell receptor (TCR) and 2) antigen-independent co-stimulation induced by interactions between co-signaling molecules expressed on antigen-presenting cells (APCs) and their T cell-expressed receptors.
The butyrophilins are closely...
Next Generation Targets for Immuno-Oncology
Tuesday, June 6, 2017 - 05:59
Anthony Person, PhD, Manager in Bioassay Development at Bio-Techne
Scott Schachtele, PhD, Product Manager at Bio-Techne
Blockade of CTLA-4 and PD-1, members of the B7/CD28 family, have proven to be the most successful cancer immunotherapies to date. While the current therapeutic focus remains on B7/CD28 family members, novel immunoregulatory pathways are being uncovered as potential targets for oncology research and cancer immunotherapy. In this presentation, we discuss some of the next generation of novel immune checkpoint molecules, including Butyrophilins (BTNs), leukocyte...
Stem Cells in the News - June 2017
Monday, June 5, 2017 - 10:46
We have captured this month's most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.
SMER28 and iPSCs Pave Possible New Treatment Option for Anemic Patients – Harvard News
Researchers from Boston Children’s Hospital have, for the first time, used patient-derived iPSCs to create red blood cells in humans with Diamond-Blackfan Anemia (DBA). DBA patients lack the erythroid cells needed to generate mature red blood cells. The team of researchers, which includes George Q. Daley and Leonard Zon, performed a chemical screening of...
Actual Living Scientist – Rachel Weller Roska
Monday, June 5, 2017 - 09:22
It recently came to our attention, from this article, that only one in three Americans can name an actual living scientist. As a large biotechnology company, filled with talented and dedicated scientists, we think that is ridiculous. We want to introduce you to some of our staff who are, in fact, Actual Living Scientists.
The next scientist in our series is Rachel Weller Roska. Rachel has been with Bio-Techne for 5 years at the R&D Systems site (and Bio-Techne Headquarters) in Minneapolis, MN. Rachel works in our Proteome Profiler Array Development Department as a Scientist...