Home / Additional Calcium Binding Protein Modulators / KN 92

KN 92

Catalog #: 4130
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4130/1
KN 92 | CAS No. 1135280-28-2 | Additional Calcium Binding Protein Modulators
1 Image
Description: Inactive analog of KN 93. K+ channel (Kv) blocker

Chemical Name: 2-[N-(4'-Methoxybenzenesulfonyl)]amino-N-(4'-chlorophenyl)-2-propenyl-N-methylbenzylamine phosphate

Purity: ≥98%

Product Details
Citations (5)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

KN 92 is an inactive analog of the CaM kinase II inhibitor KN 93 . Potassium channel (Kv1.2, 1.4, 1.5, 2.1, 3.2 and hERG) blocker in vitro.

Active Analog also available.

Technical Data

M.Wt:
554.98
Formula:
C24H25ClN2O3S.H3PO4
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1135280-28-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for KN 92

The citations listed below are publications that use Tocris products. Selected citations for KN 92 include:

5 Citations: Showing 1 - 5

  1. Amyloid-Beta Mediates Homeostatic Synaptic Plasticity.
    Authors: Thomas Et al.
    J Neurosci  2021;41:5157-5172
  2. Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models.
    Authors: Hongwei Et al.
    Sci Transl Med  2020;12
  3. Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKIIβ-GSK3β interactions.
    Authors: Kurt F Et al.
    J Neurochem  2019;149:98-110
  4. An Intrinsic Epigenetic Barrier for Functional Axon Regeneration.
    Authors: Weng Et al.
    Neuron  2017;94:337
  5. Acute SimV. inhibits K ATP channels of porcine coronary artery myocytes.
    Authors: Seto Et al.
    Oncotarget  2013;8:e66404

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