Home / Src Family Kinase Inhibitors / PP 3

PP 3

Catalog #: 2794
7 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2794/10
PP 3 | CAS No. 5334-30-5 | Src Family Kinase Inhibitors
1 Image
Description: Negative control for PP 2 (Cat. No. 1407)

Chemical Name: 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Purity: ≥98%

Product Details
Citations (7)
Supplemental Products
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

PP 3 is a negative control for the Src kinase inhibitor, PP 2. Inhibits EGFR kinase (IC50 = 2.7 μM).

Active Analog also available.

Technical Data

M.Wt:
211.22
Formula:
C11H9N5
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
5334-30-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for PP 3

The citations listed below are publications that use Tocris products. Selected citations for PP 3 include:

7 Citations: Showing 1 - 7

  1. Mathematical model of early Reelin-induced Src family kinase-mediated signaling.
    Authors: Hass Et al.
    PLoS One  2017;12:e0186927
  2. Progesterone receptor membrane component-1 regulates hepcidin biosynthesis.
    Authors: Li Et al.
    J Clin Invest  2016;126:389
  3. Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages.
    Authors: Vijayakumar Et al.
    Neural Regen Res  2015;128:251
  4. mGluR1-mediated excitation of cerebellar GABAergic interneurons requires both G protein-dependent and Src-ERK1/2-dependent signaling pathways.
    Authors: Kubota Et al.
    PLoS One  2014;9:e106316
  5. Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue.
    Authors: Rosas Et al.
    Cell  2014;9:2164
  6. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals.
    Authors: Chen Et al.
    Eur J Neurosci  2014;39:1439
  7. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.
    Authors: Kupferman Et al.
    J Neuroimmune Pharmacol  2014;158:1335

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PP 3

There are currently no reviews for this product. Be the first to review PP 3 and earn rewards!

Have you used PP 3?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.