Home / Multiplex Cytokine Assay Kits / Proteome Profiler Human XL Cytokine Array Kit

Proteome Profiler Human XL Cytokine Array Kit

Catalog #: ARY022B
168 Citations 18 Reviews Datasheet / COA / SDS
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Catalog # Availability Size / Price Qty
ARY022B
Best Seller
The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.
3 Images
Product Details
Citations (168)
FAQs
Reviews (18)
Summary Product Datasheets Data Images

Proteome Profiler Human XL Cytokine Array Kit Summary

Kit Summary

A membrane-based antibody array for the parallel determination of the relative levels of selected human cytokines and chemokines. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, plasma, human milk and saliva.

Key Benefits

  • Detects 105 human cytokines simultaneously
  • Requires no specialized equipment
  • Compatible with LI-COR* and chemiluminescence detection
*If using a LI-COR, additional reagents and protocol modifications are required.  Refer to protocol.
 

Principle of the Array

The Proteome Profiler Human XL Cytokine Array Kit is a membrane-based sandwich immunoassay. Capture antibodies spotted in duplicate on nitrocellulose membranes bind to specific target proteins present in the sample (Step 1). Captured proteins are detected with biotinylated detection antibodies (Step 2) and then visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound.

Why Use an Antibody Array to Detect Multiple Cytokines?

Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample.

 

Kit Contents
  • Rectangular 4-Well Multi-dish
  • 4 Human XL Cytokine Array nitrocellulose membranes spotted with 105 different antibodies to human cytokines
  • Array Buffer 4
  • Array Buffer 6
  • Chemi Reagent 1
  • Chemi Reagent 2
  • Detection Antibody Cocktail, Human XL Cytokine Array
  • Streptavidin-HRP
  • Transparency Overlay Template
  • Wash Buffer Concentrate (25X)

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.

Stability and Storage

Store the unopened kit at 2 °C to 8 °C. Do not use past kit expiration date.

 

Simultaneously detect the levels of these cytokines, chemokines, and acute phase proteins in a single sample.
Adiponectin/Acrp30 IFN-gamma CCL2/MCP-1
Angiogenin IGFBP-2 CCL7/MCP-3
Angiopoietin-1 IGFBP-3 M-CSF
Angiopoietin-2 IL-1 alpha/IL-1F1 MIF
Apolipoprotein A1 IL-1 beta/IL-1F2 CXCL9/MIG
BAFF/BLyS/TNFSF13B IL-1ra/IL-1F3 CCL3/CCL4 MIP-1 alpha/beta
BDNF IL-2 CCL20/MIP-3 alpha
CD14 IL-3 CCL19/MIP-3 beta
CD30 IL-4 MMP-9
CD31/PECAM-1 IL-5 Myeloperoxidase
CD40 Ligand/TNFSF5 IL-6 Osteopontin (OPN)
Chitinase 3-like IL-8 PDGF-AA
Complement Component C5/C5a IL-10 PDGF-AB/BB
Complement Factor D IL-11 Pentraxin 3/TSF-14
C-Reactive Protein/CRP IL-12 p70 CXCL4/PF4
Cripto-1 IL-13 RAGE
Cystatin C IL-15 CCL5/RANTES
Dkk-1 IL-16 RBP4
DPPIV/CD26 IL-17A Relaxin-2
EGF IL-18 BPa Resistin
CXCL5/ENA-78 IL-19 CXCL12/SDF-1 alpha
Endoglin/CD105 IL-22 Serpin E1/PAI-1
EMMPRIN IL-23 SHBG
Fas Ligand IL-24 ST2/IL1 R4
FGF basic IL-27 CCL17/TARC
KGF/FGF-7 IL-31 TFF3
FGF-19 IL-32 alpha/beta/gamma TfR
Flt-3 Ligand IL-33 TGF-alpha
G-CSF IL-34 Thrombospondin-1
GDF-15 CXCL10/IP-10 TIM-1
GM-CSF CXCL11/I-TAC TNF-alpha
CXCL1/GRO alpha Kallikrein 3/PSA uPAR
Growth Hormone (GH) Leptin VCAM-1
HGF LIF VEGF
ICAM-1/CD54 Lipocalin-2/NGAL Vitamin D BP

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Human

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Scientific Data

N/A The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. View Larger

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. HUVEC human umbilical vein endothelial cells were untreated or treated with 100 µg/mL recombinant human TNF-alpha (Catalog #210-TA) for 24 hours. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software.

N/A The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. View Larger

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. SW480 human colorectal adenocarcinoma cells were untreated or treated with 100 ng/mL of LPS for 24 hours. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software.

N/A The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. View Larger

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. THP-1 human acute monocytic leukemia cells untreated or treated with 1 µg/mL of recombinant human IFN-gamma (Catalog #285-IF) for 16 hours and 1 µ/mL of LPS for 8 hours. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software.

Citations for Proteome Profiler Human XL Cytokine Array Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

168 Citations: Showing 1 - 10
Filter your results:

Filter by:

  1. PARP14 Contributes to the Development of the Tumor-Associated Macrophage Phenotype
    Authors: Sturniolo, I;Váróczy, C;Regdon, Z;Mázló, A;Muzsai, S;Bácsi, A;Intili, G;Heged?s, C;Boothby, MR;Holechek, J;Ferraris, D;Schüler, H;Virág, L;
    International journal of molecular sciences  2024-03-22
  2. Ovarian cancer ascites confers platinum chemoresistance to ovarian cancer cells
    Authors: Carmi, YK;Agbarya, A;Khamaisi, H;Farah, R;Shechtman, Y;Korobochka, R;Gopas, J;Mahajna, J;
    Translational oncology  2024-03-14
  3. Changes in the Expression of Proteins Associated with Neurodegeneration in the Brains of Mice after Infection with Influenza A Virus with Wild Type and Truncated NS1
    Authors: Donátová, K;Mladá, M;Lopušná, K;Baran, F;Betáková, T;
    International journal of molecular sciences  2024-02-20
  4. Breast Cancer Stem Cells Secrete MIF to Mediate Tumor Metabolic Reprogramming that Drives Immune Evasion
    Authors: Yan, L;Wu, M;Wang, T;Yuan, H;Zhang, X;Zhang, H;Li, T;Pandey, V;Han, X;Lobie, PE;Zhu, T;
    Cancer research  2024-02-09
  5. The combination of cigarette smoke and solar rays causes effects similar to skin aging in a bilayer skin model
    Authors: Grenier, A;Morissette, MC;Rochette, PJ;Pouliot, R;
    Scientific reports  2023-10-20
  6. Effect of Inflammatory Microenvironment on the Regenerative Capacity of Adipose-Derived Mesenchymal Stem Cells
    Authors: Sz?cs, D;Miklós, V;Monostori, T;Guba, M;Kun-Varga, A;Póliska, S;Kis, E;Bende, B;Kemény, L;Veréb, Z;
    Cells  2023-07-29
  7. IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer
    Authors: Koncina, E;Nurmik, M;Pozdeev, VI;Gilson, C;Tsenkova, M;Begaj, R;Stang, S;Gaigneaux, A;Weindorfer, C;Rodriguez, F;Schmoetten, M;Klein, E;Karta, J;Atanasova, VS;Grzyb, K;Ullmann, P;Halder, R;Hengstschläger, M;Graas, J;Augendre, V;Karapetyan, YE;Kerger, L;Zuegel, N;Skupin, A;Haan, S;Meiser, J;Dolznig, H;Letellier, E;
    Nature communications  2023-07-17
  8. Endocrine therapy synergizes with SMAC mimetics to potentiate antigen presentation and tumor regression in hormone receptor-positive breast cancer
    Authors: Hermida-Prado, F;Xie, Y;Sherman, S;Nagy, Z;Russo, D;Akhshi, T;Chu, Z;Feit, A;Campisi, M;Chen, M;Nardone, A;Guarducci, C;Lim, K;Font-Tello, A;Lee, I;García-Pedrero, J;Canadas, I;Agudo, J;Huang, Y;Sella, T;Jin, Q;Tayob, N;Mittendorf, EA;Tolaney, SM;Qiu, X;Long, H;Symmans, WF;Lin, JR;Santagata, S;Bedrosian, I;Yardley, DA;Mayer, IA;Richardson, ET;Oliveira, G;Wu, CJ;Schuster, EF;Dowsett, M;Welm, AL;Barbie, D;Metzger, O;Jeselsohn, R;
    Cancer research  2023-07-14
  9. HMGB1, a potential regulator of tumor microenvironment in KSHV-infected endothelial cells
    Authors: Lee, MJ;Park, J;Choi, S;Yoo, SM;Park, C;Kim, HS;Lee, MS;
    Frontiers in microbiology  2023-07-13
  10. Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
    Authors: Cozzolino, K;Sanford, L;Hunter, S;Molison, K;Erickson, B;Jones, T;Ajit, D;Galbraith, MD;Espinosa, JM;Bentley, DL;Allen, MA;Dowell, RD;Taatjes, DJ;
    bioRxiv : the preprint server for biology  2023-07-05
  11. Gene Expression Changes in Cytokine and Chemokine Receptors in Association with Melanoma Liver Metastasis
    Authors: Koroknai, V;Sz�sz, I;Bal�zs, M;
    International journal of molecular sciences  2023-05-17
  12. Self-assembled peptide-substance P hydrogels alleviate inflammation and ameliorate the cartilage regeneration in knee osteoarthritis
    Authors: Kim, SJ;Kim, JE;Choe, G;Song, DH;Kim, SJ;Kim, TH;Yoo, J;Kim, SH;Jung, Y;
    Biomaterials research  2023-05-04
  13. miRNome and Proteome Profiling of Human Keratinocytes and Adipose Derived Stem Cells Proposed miRNA-Mediated Regulations of Epidermal Growth Factor and Interleukin 1-Alpha
    Authors: H Shahin, S Abdallah, J Das, W He, I El-Serafi, I Steinvall, F Sjöberg, M Elmasry, AT El-Serafi
    International Journal of Molecular Sciences, 2023-03-04;24(5):.  2023-03-04
  14. Extracellular Vesicles Derived from Three-Dimensional-Cultured Human Umbilical Cord Blood Mesenchymal Stem Cells Prevent Inflammation and Dedifferentiation in Pancreatic Islets
    Authors: E Lee, S Ha, G Kim, JH Kim, SM Jin
    Stem Cells International, 2023-02-20;2023(0):5475212.  2023-02-20
  15. gp120 Envelope Glycoproteins of HIV-1 Group M Subtype A and Subtype B Differentially Affect Gene Expression in Human Vascular Endothelial Cells
    Authors: AJ Suh, DI Suzuki, SG Gychka, TI Brelidze, YJ Suzuki
    International Journal of Molecular Sciences, 2023-02-10;24(4):.  2023-02-10
  16. Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
    Authors: ME Mohr, S Li, AM Trouten, RA Stairley, PL Roddy, C Liu, M Zhang, HM Sucov, G Tao
    bioRxiv : the preprint server for biology, 2023-02-08;0(0):.  2023-02-08
  17. Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis
    Authors: Y Mo, LL Leung, CSL Mak, X Wang, WS Chan, LMN Hui, HWM Tang, MKY Siu, R Sharma, D Xu, SKW Tsui, HYS Ngan, MMH Yung, KKL Chan, DW Chan
    Molecular Cancer, 2023-01-09;22(1):4.  2023-01-09
  18. gp120 envelope glycoproteins of HIV-1 Group M Subtype A and Subtype B differentially affect gene expression in human vascular endothelial cells
    Authors: AJ Suh, DI Suzuki, SG Gychka, TI Brelidze, YJ Suzuki
    bioRxiv : the preprint server for biology, 2023-01-03;0(0):.  2023-01-03
  19. Pericytes take up and degrade alpha-synuclein but succumb to apoptosis under cellular stress
    Authors: TJ Stevenson, RH Johnson, J Savistchen, J Rustenhove, Z Woolf, LCD Smyth, HC Murray, RLM Faull, J Correia, P Schweder, P Heppner, C Turner, R Melki, BV Dieriks, MA Curtis, M Dragunow
    Scientific Reports, 2022-10-15;12(1):17314.  2022-10-15
  20. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
    Authors: A Weigert, X Zheng, A Nenzel, K Turkowski, S Günther, E Strack, E Sirait-Fis, E Elwakeel, IM Kur, VS Nikam, C Valasaraja, H Winter, A Wissgott, R Voswinkel, F Grimminger, B Brüne, W Seeger, SS Pullamsett, R Savai
    Nature Communications, 2022-10-14;13(1):6078.  2022-10-14
  21. The Differential Paracrine Role of the Endothelium in Prostate Cancer Cells
    Authors: V Torres-Est, M Mastri, S Rosario, P Fuenzalida, CE Echeverría, E Flores, A Watts, J Cerda-Infa, VP Montecinos, PC Sotomayor, J Amigo, C Escudero, F Nualart, JML Ebos, DJ Smiraglia, AS Godoy
    Cancers, 2022-09-29;14(19):.  2022-09-29
  22. The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients
    Authors: L Saber Cher, Z Diabasana, JM Perotin, J Ancel, LMG Petit, MA Devilliers, A Bonnomet, N Lalun, G Delepine, U Maskos, P Gosset, M Polette, A Muggeo, T Guillard, G Deslée, V Dormoy
    Cells, 2022-09-20;11(19):.  2022-09-20
  23. ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model
    Authors: YY Wang, AC Hung, YC Wu, S Lo, HD Chen, YK Chen, YC Hsieh, SC Hu, MF Hou, SF Yuan
    Scientific Reports, 2022-09-14;12(1):15437.  2022-09-14
  24. Melanoma Mediated Disruption of Brain Endothelial Barrier Integrity Is Not Prevented by the Inhibition of Matrix Metalloproteinases and Proteases
    Authors: A Anchan, G Finlay, CE Angel, JJW Hucklesby, SE Graham
    Biosensors, 2022-08-19;12(8):.  2022-08-19
  25. During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes
    Authors: E Pylaeva, G Korschunow, I Spyra, S Bordbari, E Siakaeva, I Ozel, M Domnich, A Squire, A Hasenberg, K Thangavelu, T Hussain, M Goetz, KS Lang, M Gunzer, W Hansen, J Buer, A Bankfalvi, S Lang, J Jablonska
    Cell Reports, 2022-08-16;40(7):111171.  2022-08-16
  26. Cell-Type Dependent Regulation of the Electrogenic Na+/HCO3- Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma
    Authors: M Giannaki, DE Ruf, E Pfeifer, K Everaerts, DH Heiland, O Schnell, CR Rose, E Roussa
    International Journal of Molecular Sciences, 2022-08-11;23(16):.  2022-08-11
  27. Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells
    Authors: JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer
    Scientific Reports, 2022-08-01;12(1):13202.  2022-08-01
  28. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
    Authors: BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, A Katsikoudi, Y Xu, L Farrimond, R Wade-Marti, WS James, MR Turner, SA Cowley, K Talbot
    Scientific Reports, 2022-07-23;12(1):12606.  2022-07-23
  29. Targeting HIC1/TGF-beta axis-shaped prostate cancer microenvironment restrains its progression
    Authors: T Wu, W Wang, G Shi, M Hao, Y Wang, M Yao, Y Huang, L Du, X Zhang, D Ye, X Bian, J Wang
    Cell Death & Disease, 2022-07-19;13(7):624.  2022-07-19
  30. Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance
    Authors: R Islam, J Mishra, NS Polavaram, S Bhattachar, Z Hong, S Bodas, S Sharma, A Bouska, T Gilbreath, AM Said, LM Smith, BA Teply, MH Muders, SK Batra, K Datta, S Dutta
    Oncogene, 2022-07-19;40(3):111097.  2022-07-19
  31. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells
    Authors: N Igarashi, K Miyata, TM Loo, M Chiba, A Hanyu, M Nishio, H Kawasaki, H Zheng, S Toyokuni, S Kon, K Moriyama, Y Fujita, A Takahashi
    Oncogene, 2022-07-18;13(1):4157.  2022-07-18
  32. Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1
    Authors: H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd
    Mucosal Immunology, 2022-07-15;0(0):.  2022-07-15
  33. The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells
    Authors: D Ávila-Gonz, W Portillo, CP Barragán-Á, G Hernandez-, E Flores-Gar, A Molina-Her, NE Díaz-Martí, NF Díaz
    Elife, 2022-07-11;11(0):.  2022-07-11
  34. Interleukin-8 produced from cancer-associated fibroblasts suppresses proliferation of the OCUCh-LM1 cancer cell line
    Authors: R Tanaka, K Kimura, S Eguchi, G Ohira, S Tanaka, R Amano, H Tanaka, M Yashiro, M Ohira, S Kubo
    BMC Cancer, 2022-07-08;22(1):748.  2022-07-08
  35. The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer
    Authors: C Ji, M Zhang, J Hu, C Cao, Q Gu, Y Liu, X Li, D Xu, L Ying, Y Yang, H Gao, J Li, L Yu
    Cell Death & Disease, 2022-07-01;13(7):577.  2022-07-01
  36. Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium
    Authors: C Helissey, N Guitard, H Théry, S Goulinet, P Mauduit, M Girleanu, AL Favier, M Drouet, C Parnot, C Chargari, S Cavallero, S François
    Biology, 2022-06-28;11(7):.  2022-06-28
  37. Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis
    Authors: MC Cao, EE Cawston, G Chen, C Brooks, J Douwes, D McLean, ES Graham, M Dragunow, EL Scotter
    BMC neurology, 2022-06-11;22(1):216.  2022-06-11
  38. Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics
    Authors: C Giannasi, L Mangiavini, S Niada, A Colombo, E Della Mort, V Vismara, A Ambrosanio, P Savadori, S Casati, GM Peretti, AT Brini
    Pharmaceutics, 2022-06-10;14(6):.  2022-06-10
  39. Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions
    Authors: L Brandolini, M d'Angelo, R Novelli, V Castelli, C Giorgio, A Sirico, P Cocchiaro, F D'Egidio, E Benedetti, C Cristiano, A Bugatti, A Ruocco, PG Amendola, C Talarico, C Manelfi, D Iaconis, A Beccari, AU Quadros, TM Cunha, A Caruso, R Russo, A Cimini, A Aramini, M Allegretti
    Cell Death & Disease, 2022-05-25;13(5):500.  2022-05-25
  40. LCN2 is a new diagnostic biomarker and potential therapeutic target in idiopathic short stature
    Authors: X Liu, J Zhang, J Yuan, R Ding, T Liu, J Jia
    Journal of Cellular and Molecular Medicine, 2022-05-24;0(0):.  2022-05-24
  41. Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer
    Authors: M Kakarla, S ChallaSiva, MF Dufficy, V Gil, Y Filipovich, R Vickman, SE Crawford, SW Hayward, OE Franco
    Cancers, 2022-05-09;14(9):.  2022-05-09
  42. IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
    Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
    Cells, 2022-04-30;11(9):.  2022-04-30
  43. Preferential stimulation of melanocytes by M2 macrophages to produce melanin through vascular endothelial growth factor
    Authors: H Han, Y Kim, H Mo, SH Choi, K Lee, YA Rim, JH Ju
    Scientific Reports, 2022-04-19;12(1):6416.  2022-04-19
  44. ERalpha36-High Cancer-Associated Fibroblasts as an Unfavorable Factor in Triple-Negative Breast Cancer
    Authors: A Nagel, M Popeda, A Muchlinska, R Sadej, J Szade, J Zielinski, J Skokowski, M Niemira, A Kretowski, A Markiewicz, AJ Zaczek
    Cancers, 2022-04-15;14(8):.  2022-04-15
  45. Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair
    Authors: X Zhang, S Zheng, C Hu, G Li, H Lin, R Xia, Y Ye, R He, Z Li, Q Lin, R Chen, Q Zhou
    Oncogene, 2022-03-09;0(0):.  2022-03-09
  46. Isolation of Platelet-Derived Exosomes from Human Platelet-Rich Plasma: Biochemical and Morphological Characterization
    Authors: M Saumell-Es, D Delgado, G García Del, M Beitia, J Sallés, I González-B, P Sánchez, M López de J, S Barrondo, M Sánchez
    International Journal of Molecular Sciences, 2022-03-05;23(5):.  2022-03-05
  47. Na�ve Human Macrophages Are Refractory to SARS-CoV-2 Infection and Exhibit a Modest Inflammatory Response Early in Infection
    Authors: Z Zhang, R Penn, WS Barclay, ES Giotis
    Viruses, 2022-02-21;14(2):.  2022-02-21
  48. Ibuprofen in Therapeutic Concentrations Affects the Secretion of Human Bone Marrow Mesenchymal Stromal Cells, but Not Their Proliferative and Migratory Capacity
    Authors: A Kulesza, K Zielniok, J Hawryluk, L Paczek, A Burdzinska
    Biomolecules, 2022-02-10;12(2):.  2022-02-10
  49. Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome
    Authors: L Nibali, A Stephen, E Hagi-Pavli, R Allaker, AD Pino, V Terranova, M Pisano, SD Marca, V Ferrara, R Scicali, M Giordano, F Purrello, N Donos, L Malatino
    Journal of dentistry, 2022-02-06;118(0):104065.  2022-02-06
  50. Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis
    Authors: R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler
    Biomedicines, 2022-01-07;10(1):.  2022-01-07
  51. Comprehensive Molecular Landscape of Cetuximab Resistance in Head and Neck Cancer Cell Lines
    Authors: INF Gomes, RJ da Silva-O, LS da Silva, O Martinho, AF Evangelist, A van Helvoo, LF Leal, VAO Silva, SP Dos Santos, FC Nascimento, A Lopes Carv, RM Reis
    Cells, 2022-01-04;11(1):.  2022-01-04
  52. Diphenylarsinic acid induced activation of MAP kinases, transcription factors, and oxidative stress-responsive factors and hypersecretion of cytokines in cultured normal human cerebellar astrocytes
    Authors: S Sasaki, T Negishi, T Tsuzuki, K Yukawa
    Neurotoxicology, 2021-12-06;88(0):196-207.  2021-12-06
  53. Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression
    Authors: M Bolis, D Bossi, A Vallerga, V Ceserani, M Cavalli, D Impellizzi, L Di Rito, E Zoni, S Mosole, AR Elia, A Rinaldi, R Pereira Me, E D'Antonio, M Ferrari, F Stoffel, F Jermini, S Gillessen, L Bubendorf, P Schraml, A Calcinotto, E Corey, H Moch, M Spahn, G Thalmann, M Kruithof-d, MA Rubin, JP Theurillat
    Nature Communications, 2021-12-02;12(1):7033.  2021-12-02
  54. C-C Motif Chemokine Ligand-17 as a Novel Biomarker and Regulator of Epithelial Mesenchymal Transition in Renal Fibrogenesis
    Authors: YH Hsieh, WC Wang, TW Hung, CC Lee, JP Tsai
    Cells, 2021-11-29;10(12):.  2021-11-29
  55. Reduction of Oxidative Stress in Peripheral Blood Mononuclear Cells Attenuates the Inflammatory Response of Fibroblast-like Synoviocytes in Rheumatoid Arthritis
    Authors: HR Lee, SJ Yoo, J Kim, CK Park, SW Kang
    International Journal of Molecular Sciences, 2021-11-17;22(22):.  2021-11-17
  56. Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer
    Authors: WX Peng, P Koirala, H Zhou, J Jiang, Z Zhang, L Yang, YY Mo
    Cell Death & Disease, 2021-10-25;12(11):1000.  2021-10-25
  57. Cancer testis antigen PRAME: An anti-cancer target with immunomodulatory potential
    Authors: A Naik, R Thomas, G Al-Khadair, R Bacha, W Hendrickx, J Decock
    Journal of Cellular and Molecular Medicine, 2021-10-06;0(0):.  2021-10-06
  58. Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma microenvironment
    Authors: S Hong, JY You, K Paek, J Park, SJ Kang, EH Han, N Choi, S Chung, WJ Rhee, JA Kim
    Theranostics, 2021-09-27;11(19):9687-9704.  2021-09-27
  59. Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells
    Authors: L Kobari, M Auclair, O Piau, N Ferrand, M Zaoui, F Delhommeau, B Fève, M Sabbah, L Garderet
    Leukemia, 2021-09-23;0(0):.  2021-09-23
  60. Metallothionein 2A Expression in Cancer-Associated Fibroblasts and Cancer Cells Promotes Esophageal Squamous Cell Carcinoma Progression
    Authors: M Shimizu, YI Koma, H Sakamoto, S Tsukamoto, Y Kitamura, S Urakami, K Tanigawa, T Kodama, N Higashino, M Nishio, M Shigeoka, Y Kakeji, H Yokozaki
    Cancers, 2021-09-10;13(18):.  2021-09-10
  61. Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells
    Authors: N Shah, PM Hallur, RA Ganesh, P Sonpatki, D Naik, KP Chandracha, RB Puchalski, A Chaubey
    Scientific Reports, 2021-09-06;11(1):17727.  2021-09-06
  62. Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection
    Authors: P Vigneault, S Parent, P Kanda, C Michie, DR Davis, S Nattel
    Nature Communications, 2021-08-16;12(1):4963.  2021-08-16
  63. CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1
    Authors: S Durlanik, K Fundel-Cle, C Viollet, HJ Huber, M Lenter, K Kitt, S Pflanz
    Scientific Reports, 2021-07-21;11(1):14849.  2021-07-21
  64. Transcryptomic Analysis of Human Brain -Microvascular Endothelial Cell Driven Changes in -Vascular Pericytes
    Authors: L Kurmann, M Okoniewski, RK Dubey
    Cells, 2021-07-14;10(7):.  2021-07-14
  65. Prophylactic role of Korean Red Ginseng in astrocytic mitochondrial biogenesis through HIF-1alpha
    Authors: J Park, M Lee, M Kim, S Moon, S Kim, S Kim, SH Koh, YM Kim, YK Choi
    Journal of Ginseng Research, 2021-07-12;46(3):408-417.  2021-07-12
  66. Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC
    Authors: RN Hawthorne, A Blazeski, J Lowenthal, S Kannan, R Teuben, D DiSilvestr, J Morrissett, JE Saffitz, KR Boheler, CA James, SP Chelko, G Tomaselli, L Tung
    Journal of Clinical Medicine, 2021-07-10;10(14):.  2021-07-10
  67. Combination of Epithelial Growth Factor Receptor Blockers and CDK4/6 Inhibitor for Nasopharyngeal Carcinoma Treatment
    Authors: HP Li, CY Huang, KW Lui, YK Chao, CN Yeh, LY Lee, Y Huang, TL Lin, YC Kuo, MY Huang, YR Lai, YM Yeh, HC Fan, AC Lin, JC Hsieh, KP Chang, CY Lin, HM Wang, YS Chang, CL Hsu
    Cancers, 2021-06-12;13(12):.  2021-06-12
  68. Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
    Authors: LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller
    Nature Communications, 2021-06-10;12(1):3543.  2021-06-10
  69. CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity
    Authors: P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, K Lehti, M Nykter, V Le Joncour, P Laakkonen
    JCI Insight, 2021-05-10;6(9):.  2021-05-10
  70. Transcryptomic Analysis of Human Brain-Microvascular Endothelial Response to -Pericytes: Cell Orientation Defines Barrier Function
    Authors: L Kurmann, M Okoniewski, OO Ogunshola, B Leeners, B Imthurn, RK Dubey
    Cells, 2021-04-20;10(4):.  2021-04-20
  71. Efficacy of chitinase-3-like protein 1 as an in�vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells
    Authors: N Komabashir, F Suehiro, M Ishii, M Nishimura
    Regenerative Therapy, 2021-03-27;18(0):38-50.  2021-03-27
  72. Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study
    Authors: RLI Crake, MR Strother, E Phillips, MP Doogue, M Zhang, CMA Frampton, BA Robinson, MJ Currie
    Scientific Reports, 2021-03-11;11(1):5648.  2021-03-11
  73. Adhesion strength and contractility enable metastatic cells to become adurotactic
    Authors: B Yeoman, G Shatkin, P Beri, A Banisadr, P Katira, AJ Engler
    Cell Reports, 2021-03-09;34(10):108816.  2021-03-09
  74. Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age
    Authors: D Delgado, AM Bilbao, M Beitia, A Garate, P Sánchez, I González-B, A Isasti, M López De J, J Zuazo-Ibar, A Montilla, M Domercq, E Capetillo-, G García Del, J Sallés, C Matute, M Sánchez
    International Journal of Molecular Sciences, 2021-02-09;22(4):.  2021-02-09
  75. GSTM1 Modulates Expression of Endothelial Adhesion Molecules in Uremic Milieu
    Authors: D Jerotic, S Suvakov, M Matic, A Alqudah, DJ Grieve, M Pljesa-Erc, A Savic-Rado, T Damjanovic, N Dimkovic, L McClements, T Simic
    Oxidative Medicine and Cellular Longevity, 2021-01-25;2021(0):6678924.  2021-01-25
  76. Tear-Derived Exosome Proteins Are Increased in Patients with Thyroid Eye Disease
    Authors: JS Han, SE Kim, JQ Jin, NR Park, JY Lee, HL Kim, SB Lee, SW Yang, DJ Lim
    International Journal of Molecular Sciences, 2021-01-23;22(3):.  2021-01-23
  77. Suprabasin-derived bioactive peptides identified by plasma peptidomics
    Authors: T Taguchi, Y Kodera, K Oba, T Saito, Y Nakagawa, Y Kawashima, M Shichiri
    Scientific Reports, 2021-01-13;11(1):1047.  2021-01-13
  78. Regulation of PD-L1 expression is a novel facet of cyclic-AMP-mediated immunosuppression
    Authors: B Sasi, P Ethiraj, J Myers, AP Lin, S Jiang, Z Qiu, KN Holder, RCT Aguiar
    Leukemia, 2020-12-09;0(0):.  2020-12-09
  79. Serum-Derived Exosomal MicroRNA Profiles Can Predict Poor Survival Outcomes in Patients with Extranodal Natural Killer/T-Cell Lymphoma
    Authors: KJ Ryu, JY Lee, ME Choi, SE Yoon, J Cho, YH Ko, JH Shim, WS Kim, C Park, SJ Kim
    Cancers, 2020-11-27;12(12):.  2020-11-27
  80. Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages
    Authors: YY Wang, HD Chen, S Lo, YK Chen, YC Huang, SC Hu, YC Hsieh, AC Hung, MF Hou, SF Yuan
    Cancers, 2020-11-26;12(12):.  2020-11-26
  81. Excess of the NF-?B p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms
    Authors: Y Kravtsova-, G Goldhirsh, A Ivantsiv, O Ben Itzhak, YT Kwon, E Pikarsky, A Ciechanove
    Proc Natl Acad Sci U S A, 2020-11-09;0(0):.  2020-11-09
  82. Unique inflammatory signature in haemophilic arthropathy: miRNA changes due to interaction between blood and fibroblast-like synoviocytes
    Authors: S Mignot, N Cagnard, B Albaud, C Bally, J Siavellis, O Hermine, L Frenzel
    J Cell Mol Med, 2020-11-07;0(0):.  2020-11-07
  83. Vadadustat, a HIF Prolyl Hydroxylase Inhibitor, Improves Immunomodulatory Properties of Human Mesenchymal Stromal Cells
    Authors: K Zielniok, A Burdzinska, B Kaleta, R Zagozdzon, L Paczek
    Cells, 2020-11-01;9(11):.  2020-11-01
  84. Chemerin-156 is the Active Isoform in Human Hepatic Stellate Cells
    Authors: M Spirk, S Zimny, M Neumann, N McMullen, CJ Sinal, C Buechler
    Int J Mol Sci, 2020-10-13;21(20):.  2020-10-13
  85. SFMBT2-Mediated Infiltration of Preadipocytes and TAMs in Prostate Cancer
    Authors: J Gwak, H Jeong, K Lee, JY Shin, T Sim, J Na, J Kim, BG Ju
    Cancers, 2020-09-22;12(9):.  2020-09-22
  86. Tissue cytokine/chemokine profile in vulvar lichen sclerosus: An observational study on keratinocyte and fibroblast cultures
    Authors: M Corazza, L Oton-Gonza, V Scuderi, JC Rotondo, C Lanzillott, G Di Mauro, M Tognon, F Martini, A Borghi
    J Dermatol Sci, 2020-09-19;0(0):.  2020-09-19
  87. Isolation and Characterization of Human Synovial Fluid-Derived Mesenchymal Stromal Cells from Popliteal Cyst
    Authors: F Li, J Chen, M Gong, Y Bi, C Hu, Y Zhang, M Li
    Stem Cells Int, 2020-09-18;2020(0):7416493.  2020-09-18
  88. Zoledronic Acid Abrogates Restraint Stress-Induced Macrophage Infiltration, PDGF-AA Expression, and Ovarian Cancer Growth
    Authors: CB Colon-Eche, T Ortiz, L Maldonado, MJ Hidalgo-Va, J Pérez-Mora, AN Aquino-Ace, R Herrera-No, M Bonilla-Cl, EM Castro, GN Armaiz-Pen
    Cancers, 2020-09-18;12(9):.  2020-09-18
  89. Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis
    Authors: G Ye, Z Xie, H Zeng, P Wang, J Li, G Zheng, S Wang, Q Cao, M Li, W Liu, S Cen, Z Li, Y Wu, Z Ye, H Shen
    Cell Death Dis, 2020-09-17;11(9):775.  2020-09-17
  90. Cytokine changes during treatment of anti-Caspr2 encephalitis: a case report
    Authors: YC Wei, CL Wu, WC Weng
    BMC Neurol, 2020-08-13;20(1):299.  2020-08-13
  91. Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia
    Authors: HH Park, HN Kim, H Kim, Y Yoo, H Shin, EY Choi, JS Bae, W Lee
    Sci Adv, 2020-07-31;6(31):.  2020-07-31
  92. IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an A&beta-Induced Gene Regulatory Network
    Authors: S Martins, A Müller-Sch, L Erichsen, M Bohndorf, W Wruck, K Sleegers, C Van Broeck, C Korth, J Adjaye
    Int J Mol Sci, 2020-06-25;21(12):.  2020-06-25
  93. Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance
    Authors: CM Garvey, R Lau, A Sanchez, RX Sun, EJ Fong, ME Doche, O Chen, A Jusuf, HJ Lenz, B Larson, SM Mumenthale
    Cancers (Basel), 2020-05-28;12(6):.  2020-05-28
  94. TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades
    Authors: SA Scarneo, KW Yang, JR Roques, A Dai, LS Eibschutz, P Hughes, TAJ Haystead
    Oncotarget, 2020-05-26;11(21):1961-1970.  2020-05-26
  95. Human amniotic mesenchymal stromal cells promote bone regeneration via activating endogenous regeneration
    Authors: F Jiang, W Zhang, M Zhou, Z Zhou, M Shen, N Chen, X Jiang
    Theranostics, 2020-05-15;10(14):6216-6230.  2020-05-15
  96. Intermittent hypoxia modulates redox homeostasis, lipid metabolism associated inflammatory processes and redox post-translational modifications: Benefits at high altitude
    Authors: A Gangwar, S Paul, Y Ahmad, K Bhargava
    Sci Rep, 2020-05-13;10(1):7899.  2020-05-13
  97. Progenitor Cells Activated by Platelet Lysate in Human Articular Cartilage as a Tool for Future Cartilage Engineering and Reparative Strategies
    Authors: S Carluccio, D Martinelli, MEF Palamà, RC Pereira, R Benelli, A Guijarro, R Cancedda, C Gentili
    Cells, 2020-04-23;9(4):.  2020-04-23
  98. Impact of Type 2 Diabetes Mellitus on Human Bone Marrow Stromal Cell Number and Phenotypic Characteristics
    Authors: FC Cassidy, C Shortiss, CG Murphy, SR Kearns, W Curtin, C De Buitléi, T O'Brien, CM Coleman
    Int J Mol Sci, 2020-04-02;21(7):.  2020-04-02
  99. Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin
    Authors: S Schwarz, LM Gockel, A Naggi, U Barash, M Gobec, G Bendas, M Schlesinge
    Molecules, 2020-02-26;25(5):.  2020-02-26
  100. Permanent Pro-Tumorigenic Shift in Adipose Tissue-Derived Mesenchymal Stromal Cells Induced by Breast Malignancy
    Authors: J Plava, M Cihova, M Burikova, M Bohac, M Adamkov, S Drahosova, D Rusnakova, D Pindak, M Karaba, J Simo, M Mego, L Danisovic, L Kucerova, S Miklikova
    Cells, 2020-02-19;9(2):.  2020-02-19
  101. Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts
    Authors: T Yamanaka, N Harimoto, T Yokobori, R Muranushi, K Hoshino, K Hagiwara, D Gantumur, T Handa, N Ishii, M Tsukagoshi, T Igarashi, H Tanaka, A Watanabe, N Kubo, K Araki, K Shirabe
    Br. J. Cancer, 2020-02-04;0(0):.  2020-02-04
  102. Resveratrol as Inducer of Autophagy, Pro-Survival, and Anti-Inflammatory Stimuli in Cultured Human RPE Cells
    Authors: N Josifovska, R Albert, R Nagymihály, L Lytvynchuk, MC Moe, K Kaarnirant, ZJ Veréb, G Petrovski
    Int J Mol Sci, 2020-01-27;21(3):.  2020-01-27
  103. Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction
    Authors: B Wernly, V Paar, A Aigner, PM Pilz, BK Podesser, M Förster, C Jung, JP Hofbauer, B Tockner, M Wimmer, T Kraus, LJ Motloch, M Hackl, UC Hoppe, A Kiss, M Lichtenaue
    Cells, 2020-01-25;9(2):.  2020-01-25
  104. Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPAR&gamma Ligands as a Potential Target in Breast Cancer
    Authors: G Gionfriddo, P Plastina, G Augimeri, S Catalano, C Giordano, I Barone, C Morelli, F Giordano, L Gelsomino, D Sisci, R Witkamp, S Andò, K van Norren, D Bonofiglio
    Cells, 2020-01-10;9(1):.  2020-01-10
  105. Intrathecal Infusion of Autologous Adipose-Derived Regenerative Cells in Autoimmune Refractory Epilepsy: Evaluation of Safety and Efficacy
    Authors: E Szczepanik, H Mierzewska, D Antczak-Ma, A Figiel-Dab, I Terczynska, J Tryfon, N Krzesniak, BH Noszczyk, E Sawicka, K Domanska-J, A Sarnowska
    Stem Cells Int, 2020-01-03;2020(0):7104243.  2020-01-03
  106. Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products
    Authors: M Laggner, A Gugerell, C Bachmann, H Hofbauer, V Vorstandle, M Seibold, G Gouya Lech, A Peterbauer, S Madlener, S Demyanets, D Sorgenfrey, T Ostler, M Erb, M Mildner, HJ Ankersmit
    Stem Cell Res Ther, 2020-01-03;11(1):9.  2020-01-03
  107. CCR2 signaling in breast carcinoma cells promotes tumor growth and invasion by promoting CCL2 and suppressing CD154 effects on the angiogenic and immune microenvironments
    Authors: G Brummer, W Fang, C Smart, B Zinda, N Alissa, C Berkland, D Miller, N Cheng
    Oncogene, 2019-12-11;0(0):.  2019-12-11
  108. Extracellular Membrane Vesicles from Lactobacilli Dampen IFN-gamma Responses in a Monocyte-Dependent Manner
    Authors: M Mata Forsb, S Björkander, Y Pang, L Lundqvist, M Ndi, M Ott, IB Escribá, MC Jaeger, S Roos, E Sverremark
    Sci Rep, 2019-11-19;9(1):17109.  2019-11-19
  109. Physiologic expansion of human heart-derived cells enhances therapeutic repair of injured myocardium
    Authors: S Mount, P Kanda, S Parent, S Khan, C Michie, L Davila, V Chan, RA Davies, H Haddad, D Courtman, DJ Stewart, DR Davis
    Stem Cell Res Ther, 2019-11-04;10(1):316.  2019-11-04
  110. Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development
    Authors: O Malaise, Y Tachikart, M Constantin, M Mumme, R Ferreira-L, S Noack, C Krettek, D Noël, J Wang, C Jorgensen, JM Brondello
    Aging (Albany NY), 2019-10-22;11(20):9128-9146.  2019-10-22
  111. PRMT6 promotes lung tumor progression via the alternate activation of tumor-associated macrophages
    Authors: S Avasarala, PY Wu, SQ Khan, S Yanlin, M Van Scoyk, J Bao, A Di Lorenzo, O David, MT Bedford, V Gupta, RA Winn, RK Bikkavilli
    Mol. Cancer Res., 2019-10-16;0(0):.  2019-10-16
  112. Interleukin-6 mediates resistance to PI3K-pathway-targeted therapy in lymphoma
    Authors: JH Kim, WS Kim, C Park
    BMC Cancer, 2019-10-10;19(1):936.  2019-10-10
  113. Inflammation-Related Patterns in the Clinical Staging and Severity Assessment of Chronic Kidney Disease
    Authors: S Mihai, E Codrici, ID Popescu, AM Enciu, E Rusu, D Zilisteanu, LG Necula, G Anton, C Tanase
    Dis. Markers, 2019-10-07;2019(0):1814304.  2019-10-07
  114. Tissue-regenerative potential of the secretome of gamma-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis
    Authors: E Simader, L Beer, M Laggner, V Vorstandle, A Gugerell, M Erb, P Kalinina, D Copic, D Moser, A Spittler, E Tschachler, H Jan Ankers, M Mildner
    Cell Death Dis, 2019-09-30;10(10):729.  2019-09-30
  115. Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma
    Authors: J Wurm, SP Behringer, VM Ravi, K Joseph, N Neidert, JP Maier, R Doria-Medi, M Follo, D Delev, D Pfeifer, J Beck, R Sankowski, O Schnell, DH Heiland
    Cancers (Basel), 2019-09-26;11(10):.  2019-09-26
  116. The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues
    Authors: Y Wada, T Ikemoto, Y Morine, S Imura, Y Saito, S Yamada, M Shimada
    Sci Rep, 2019-09-13;9(1):13204.  2019-09-13
  117. The Secretomes of Painful Versus Nonpainful Human Schwannomatosis Tumor Cells Differentially Influence Sensory Neuron Gene Expression and Sensitivity
    Authors: KL Ostrow, KJ Donaldson, MJ Caterina, A Belzberg, A Hoke
    Sci Rep, 2019-09-11;9(1):13098.  2019-09-11
  118. Radiotherapy-Induced Changes in the Systemic Immune and Inflammation Parameters of Head and Neck Cancer Patients
    Authors: K Balázs, E Kis, C Badie, EN Bogdándi, S Candéias, LC Garcia, I Dominczyk, B Frey, U Gaipl, Z Jurányi, ZS Kocsis, EA Rutten, G Sáfrány, P Widlak, K Lumniczky
    Cancers (Basel), 2019-09-06;11(9):.  2019-09-06
  119. Hypoxia Rapidly Induces the Expression of Cardiomyogenic Factors in Human Adipose-Derived Adherent Stromal Cells
    Authors: JW Choi, H Moon, SE Jung, S Lim, S Lee, IK Kim, HB Lee, J Lee, BW Song, SW Kim, KC Hwang
    J Clin Med, 2019-08-15;8(8):.  2019-08-15
  120. Obesity in acute alcoholic hepatitis increases morbidity and mortality
    Authors: R Parker, SJ Kim, GY Im, J Nahas, B Dhesi, N Vergis, A Sinha, A Ghezzi, MR Rink, A McCune, GP Aithal, PN Newsome, CJ Weston, A Holt, B Gao
    EBioMedicine, 2019-07-03;45(0):511-518.  2019-07-03
  121. Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma
    Authors: D Henrik Hei, VM Ravi, SP Behringer, JH Frenking, J Wurm, K Joseph, NWC Garrelfs, J Strähle, S Heynckes, J Grauvogel, P Franco, I Mader, M Schneider, AL Potthoff, D Delev, UG Hofmann, C Fung, J Beck, R Sankowski, M Prinz, O Schnell
    Nat Commun, 2019-06-11;10(1):2541.  2019-06-11
  122. Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice
    Authors: S Marino, D de Ridder, RT Bishop, N Renema, M Ponzetti, A Sophocleou, M Capulli, A Aljeffery, G Carrasco, MD Gens, A Khogeer, SH Ralston, J Gertsch, F Lamoureux, D Heymann, N Rucci, AI Idris
    EBioMedicine, 2019-05-29;44(0):452-466.  2019-05-29
  123. p16INK4A-expressing mesenchymal stromal cells restore the senescence-clearance-regeneration sequence that is impaired in chronic muscle inflammation
    Authors: TS Chikenji, Y Saito, N Konari, M Nakano, Y Mizue, M Otani, M Fujimiya
    EBioMedicine, 2019-05-23;0(0):.  2019-05-23
  124. Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature
    Authors: LS Spitzhorn, M Megges, W Wruck, MS Rahman, J Otte, Ö Degistiric, R Meisel, RV Sorg, ROC Oreffo, J Adjaye
    Stem Cell Res Ther, 2019-03-18;10(1):100.  2019-03-18
  125. Abnormal inhibition of osteoclastogenesis by mesenchymal stem cells through the miR-4284/CXCL5 axis in ankylosing spondylitis
    Authors: W Liu, P Wang, Z Xie, S Wang, M Ma, J Li, M Li, S Cen, S Tang, G Zheng, G Ye, X Wu, Y Wu, H Shen
    Cell Death Dis, 2019-02-25;10(3):188.  2019-02-25
  126. Blockage of TGF-? Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells
    Authors: Y Li, H Li, Y Duan, X Cai, D You, F Zhou, C Yang, X Tuo, Z Liu
    Biomed Res Int, 2019-02-18;2019(0):8231267.  2019-02-18
  127. The Composition of Hyperacute Serum and Platelet-Rich Plasma Is Markedly Different despite the Similar Production Method
    Authors: D Kardos, M Simon, G Vácz, A Hinsenkamp, T Holczer, D Cseh, A Sárközi, K Szenthe, F Bánáti, S Szathmary, S Nehrer, O Kuten, M Masteling, Z Lacza, I Hornyák
    Int J Mol Sci, 2019-02-08;20(3):.  2019-02-08
  128. Ectoine-Containing Inhalation Solution versus Saline Inhalation Solution in the Treatment of Acute Bronchitis and Acute Respiratory Infections: A Prospective, Controlled, Observational Study
    Authors: BH Tran, VA Dao, A Bilstein, K Unfried, K Shah-Hosse, R Mösges
    Biomed Res Int, 2019-01-31;2019(0):7945091.  2019-01-31
  129. A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
    Authors: M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos
    Cell Rep, 2018-12-26;25(13):3706-3720.e8.  2018-12-26
  130. Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion
    Authors: SA Scarneo, A Mansourati, LS Eibschutz, J Totzke, JR Roques, D Loiselle, D Carlson, P Hughes, TAJ Haystead
    Sci Rep, 2018-11-19;8(1):17058.  2018-11-19
  131. VSIG-3 as a ligand of VISTA inhibits human T-cell function.
    Authors: Wang J, Wu G, Manick B, Hernandez V, Renelt M, Erickson C, Guan J, Singh R, Rollins S, Solorz A, Bi M, Li J, Grabowski D, Dirkx J, Tracy C, Stuart T, Ellinghuysen C, Desmond D, Foster C, Kalabokis V
    Immunology, 2018-10-10;156(1):74-85.  2018-10-10
  132. USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and ?-TrCP and promotes cancer malignancy
    Authors: YC Wang, YS Wu, CY Hung, SA Wang, MJ Young, TI Hsu, JJ Hung
    Nat Commun, 2018-09-28;9(1):3996.  2018-09-28
  133. Ca2+ Signaling and IL-8 Secretion in Human Testicular Peritubular Cells Involve the Cation Channel TRPV2
    Authors: K Eubler, C Herrmann, A Tiefenbach, FM Köhn, JU Schwarzer, L Kunz, A Mayerhofer
    Int J Mol Sci, 2018-09-19;19(9):.  2018-09-19
  134. Gle1 mediates stress granule-dependent survival during chemotoxic stress
    Authors: L Glass, SR Wente
    Adv Biol Regul, 2018-09-18;0(0):.  2018-09-18
  135. Acid-electrolyzed functional water induces extracellular matrix metalloproteinase inducer, a possible novel alarmin, secretion from oral squamous cell carcinoma cell lines
    Authors: M Kusunoki, E Sata, K Nishio, T Tanaka, T Nishida, N Sugano, S Sato, M Asano
    Int J Med Sci, 2018-09-07;15(12):1365-1372.  2018-09-07
  136. Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis
    Authors: P Garcia-Rei, A Phillips, TM Piers, C Villegas-L, M Butler, A Mallach, C Rodrigues, CE Arber, A Heslegrave, H Zetterberg, H Neumann, S Neame, H Houlden, J Hardy, JM Pocock
    Cell Rep, 2018-08-28;24(9):2300-2311.  2018-08-28
  137. A static magnetic field inhibits the expression of platelet-derived growth factor-AA in human oral squamous cell carcinoma
    Authors: M Obayashi-I, S Saito, D Omagari, M Asano, T Ishigami
    J Oral Sci, 2018-08-25;0(0):.  2018-08-25
  138. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
    Nat Commun, 2018-08-15;9(1):3267.  2018-08-15
  139. Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells
    Authors: KA Cavassani, RJ Meza, DM Habiel, JF Chen, A Montes, M Tripathi, GA Martins, TR Crother, S You, CM Hogaboam, N Bhowmick, EM Posadas
    Cancer Med, 2018-08-09;0(0):.  2018-08-09
  140. Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite
    Authors: N Li, C Wang, S Sun, C Zhang, D Lü, Q Chen, M Long
    Front Physiol, 2018-07-31;9(0):1025.  2018-07-31
  141. Increased Dkk-1 plasma levels may discriminate disease subtypes in myeloproliferative neoplasms
    Authors: C Mambet, L Necula, S Mihai, L Matei, C Bleotu, M Chivu-Econ, O Stanca, A Tatic, N Berbec, C Tanase, CC Diaconu
    J. Cell. Mol. Med., 2018-07-05;0(0):.  2018-07-05
  142. IL-23 secreted by myeloid cells drives castration-resistant prostate cancer
    Authors: A Calcinotto, C Spataro, E Zagato, D Di Mitri, V Gil, M Crespo, G De Bernard, M Losa, M Mirenda, E Pasquini, A Rinaldi, S Sumanasuri, MB Lambros, A Neeb, R Lucianò, CA Bravi, D Nava-Rodri, D Dolling, T Prayer-Gal, A Ferreira, A Briganti, A Esposito, S Barry, W Yuan, A Sharp, J de Bono, A Alimonti
    Nature, 2018-06-27;0(0):.  2018-06-27
  143. Unique and shared inflammatory profiles of human brain endothelia and pericytes
    Authors: LCD Smyth, J Rustenhove, TI Park, P Schweder, D Jansson, PA Heppner, SJ O'Carroll, EW Mee, RLM Faull, M Curtis, M Dragunow
    J Neuroinflammation, 2018-05-11;15(1):138.  2018-05-11
  144. Epithelial cell-derived cytokines CST3 and GDF15 as potential therapeutics for pulmonary fibrosis
    Authors: YI Kim, HW Shin, YS Chun, CH Cho, J Koh, DH Chung, JW Park
    Cell Death Dis, 2018-05-01;9(5):506.  2018-05-01
  145. CST3 and GDF15 ameliorate renal fibrosis by inhibiting fibroblast growth and activation
    Authors: YI Kim, HW Shin, YS Chun, JW Park
    Biochem. Biophys. Res. Commun., 2018-04-13;0(0):.  2018-04-13
  146. Neurofibromin knockdown in glioma cell lines is associated with changes in cytokine and chemokine secretion in vitro
    Authors: MD Wood, J Mukherjee, RO Pieper
    Sci Rep, 2018-04-11;8(1):5805.  2018-04-11
  147. Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration
    Authors: X de la Rosa, PC Norris, N Chiang, AR Rodriguez, BW Spur, CN Serhan
    Am. J. Pathol., 2018-04-01;188(4):950-966.  2018-04-01
  148. Allele-specific long-distance regulation dictates IL-32 isoform switching and mediates susceptibility to HIV-1
    Authors: RJ Palstra, E de Crignis, MD Röling, T van Staver, TW Kan, W van Ijcken, YM Mueller, PD Katsikis, T Mahmoudi
    Sci Adv, 2018-02-21;4(2):e1701729.  2018-02-21
  149. Withaferin A Associated Differential Regulation of Inflammatory Cytokines
    Authors: S Dubey, H Yoon, MS Cohen, P Nagarkatti, M Nagarkatti, D Karan
    Front Immunol, 2018-02-09;9(0):195.  2018-02-09
  150. Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine
    Authors: P Chang, B Zhang, L Shao, W Song, W Shi, L Wang, T Xu, D Li, X Gao, Y Qu, L Dong, J Wang
    Cell Death Dis, 2018-02-05;9(2):154.  2018-02-05
  151. ATP-mediated Events in Peritubular Cells Contribute to Sterile Testicular Inflammation
    Authors: L Walenta, D Fleck, T Fröhlich, H von Eysmon, GJ Arnold, J Spehr, JU Schwarzer, FM Köhn, M Spehr, A Mayerhofer
    Sci Rep, 2018-01-23;8(1):1431.  2018-01-23
  152. Efficient scalable production of therapeutic microvesicles derived from human mesenchymal stem cells
    Authors: JM Cha, EK Shin, JH Sung, GJ Moon, EH Kim, YH Cho, HD Park, H Bae, J Kim, OY Bang
    Sci Rep, 2018-01-19;8(1):1171.  2018-01-19
  153. Hypoxia-induced upregulation of angiogenic factors in immortalized human periodontal ligament fibroblasts
    Authors: T Kifune, H Ito, M Ishiyama, S Iwasa, H Takei, T Hasegawa, M Asano, T Shirakawa
    J Oral Sci, 2018-01-01;60(4):519-525.  2018-01-01
  154. Obesity Enhances the Conversion of Adipose-Derived Stromal/Stem Cells into Carcinoma-Associated Fibroblast Leading to Cancer Cell Proliferation and Progression to an Invasive Phenotype
    Authors: AL Strong, DT Pei, CG Hurst, JM Gimble, ME Burow, BA Bunnell
    Stem Cells Int, 2017-12-17;2017(0):9216502.  2017-12-17
  155. Lack of Evidence for Vasoactive and Inflammatory Mediators in the Promotion of Macular Edema Associated with Epiretinal Membranes
    Authors: BP Applewhite, S Babapoor-F, D Poon, SJ Hassan, E Wellmann, HS Ying, GL Semenza, S Montaner, A Sodhi
    Sci Rep, 2017-09-06;7(1):10608.  2017-09-06
  156. Histone Deacetylase 1 Depletion Activates Human Cardiac Mesenchymal Stromal Cell Proangiogenic Paracrine Signaling Through a Mechanism Requiring Enhanced Basic Fibroblast Growth Factor Synthesis and Secretion
    Authors: JB Moore, J Zhao, AG Fischer, MCL Keith, D Hagan, M Wysoczynsk, R Bolli
    J Am Heart Assoc, 2017-07-05;6(7):.  2017-07-05
  157. Protective Effect of Let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis
    Authors: E Brennan, B Wang, A McClelland, M Mohan, M Marai, O Beuscart, S Derouiche, S Gray, R Pickering, C Tikellis, M de Gaetano, M Barry, O Belton, ST Ali-Shah, P Guiry, KA Jandeleit-, ME Cooper, C Godson, P Kantharidi
    Diabetes, 2017-05-09;0(0):.  2017-05-09
  158. Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST-Segment Elevation Myocardial Infarction
    Authors: S Chandran, J Watkins, A Abdul-Aziz, M Shafat, PA Calvert, KM Bowles, MD Flather, SA Rushworth, AD Ryding
    J Am Heart Assoc, 2017-05-03;6(5):.  2017-05-03
  159. An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells
    Authors: A Sasahara, K Tominaga, T Nishimura, M Yano, E Kiyokawa, M Noguchi, M Noguchi, H Kanauchi, T Ogawa, H Minato, K Tada, Y Seto, A Tojo, N Gotoh
    Oncotarget, 2017-04-11;8(15):24869-24881.  2017-04-11
  160. Extravillous Trophoblast and Endothelial Cell Crosstalk Mediates Leukocyte Infiltration to the Early Remodeling Decidual Spiral Arteriole Wall
    Authors: RH Choudhury, CE Dunk, SJ Lye, JD Aplin, LK Harris, RL Jones
    J. Immunol., 2017-04-10;0(0):.  2017-04-10
  161. Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis
    Authors: K Jin, NB Pandey, AS Popel
    Oncotarget, 2017-01-01;0(0):.  2017-01-01
  162. Pretreatment of IL-1? enhances proliferation and chondrogenic potential of synovium-derived mesenchymal stem cells
    Authors: Etsuko Matsumura
    Cytotherapy, 2016-12-12;0(0):.  2016-12-12
  163. Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer
    Oncotarget, 2016-11-29;0(0):.  2016-11-29
  164. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages
    Sci Rep, 2016-07-12;6(0):29588.  2016-07-12
  165. Identification of Pathways in Liver Repair Potentially Targeted by Secretory Proteins from Human Mesenchymal Stem Cells
    Int J Mol Sci, 2016-07-09;17(7):.  2016-07-09
  166. Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts
    Authors: Jin Ah Kim
    PLoS ONE, 2016-06-13;11(6):e0157058.  2016-06-13
  167. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
    Nature, 2016-05-18;533(7604):493-8.  2016-05-18
  168. Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo.
    Authors: Westman J, Papareddy P, Dahlgren M, Chakrakodi B, Norrby-Teglund A, Smeds E, Linder A, Morgelin M, Johansson-Lindbom B, Egesten A, Herwald H
    PLoS Pathog, 2015-12-08;11(12):e1005319.  2015-12-08

FAQs

  1. Will the Array identification number stamped on the Array membrane interfere with detection if it is not cut-off before the membrane is blocked?

    • The dye used for printing the Array identification number on the membranes will fluoresce and interfere with the LI-COR detection. It is critical that the number is cut off before beginning the experiment. 

  2. Could you tell us whether this MMP-9 antibody can detect TIMP and MMP-9 complex?

    • We haven't performed a large amount of specificity testing per each spot in the arrays because these are qualitative screening tools. However, we would recommend treating the MMP-9 spot as a "Total MMP-9" detecting both free MMP-9 and MMP-9 in complex. If the MMP-9 spot turns out to be of high interest for the customer's study, they will want to examine this target in more detail with quantitative tools such as ELISA or Luminex.

View all Proteome Profiler Antibody Array FAQs

Reviews for Proteome Profiler Human XL Cytokine Array Kit

Average Rating: 4.6 (Based on 18 Reviews)

5 Star
61.11%
4 Star
38.89%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Proteome Profiler Human XL Cytokine Array Kit?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 05/13/2022

Product was easy to use and quick. In house analysis software would improve the process. Array has not been tested if the specific antibodies differentiate between precursor and mature proteins or bound vs unbound proteins. Testing this would increase applicability. Image provided is an example of 100 ul of human serum.

Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 12/02/2021
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 10/21/2021
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 09/07/2021
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 04/29/2021

Used 1 ml of pooled basal media from air-liquid interface cultures of primary epithelial cells

Protocol very easy to follow, but data analysis can be tricky. Would benefit massively from coming with its own analysis tool / ImageJ plugin.

Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 10/20/2020
Proteome Profiler Human XL Cytokine Array Kit
By Dhanush Haspula on 05/22/2020

220 uL of rat plasma for overnight incubation with arrays at 4c.

Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Louise Reynolds on 02/18/2020

Human endothelial cells treated +/- FAK kinase inhibitors +/- doxorubicin

Proteome Profiler Human XL Cytokine Array Kit
By Lucia Lisi on 01/14/2020

Chiavari M, Ciotti GMP, Navarra P, Lisi L. Pro-Inflammatory Activation of A New Immortalized Human Microglia Cell Line. Brain Sci. 2019;9(5):111. Published 2019 May 15. doi:10.3390/brainsci9050111

Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Fadi Saadeh on 07/01/2019
Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 06/07/2019
Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 06/06/2019
Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 02/07/2019
Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Ivan Luzardo on 01/03/2019
Proteome Profiler Human XL Cytokine Array Kit
By Samantha Scarneo on 12/26/2018
Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Scott Scarneo on 12/12/2018

THP-1 Cells stimulated with LPS+IFN gamma for 24 hours.

Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Anonymous on 09/14/2018
Proteome Profiler Human XL Cytokine Array Kit ARY022B
Proteome Profiler Human XL Cytokine Array Kit
By Leslie Priddy on 04/01/2018