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SIS17

Catalog #: 7969 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7969/10
7969/50
SIS17 | CAS No. 2374313-54-7 | HDAC11
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Description: Selective HDAC11 inhibitor

Chemical Name: N'-Hexadecylthiophene-2-carbohydrazide

Purity: ≥95%

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Biological Activity

SIS17 is a selective HDAC11 inhibitor (IC50 = 0.83 μM). Inhibits demyristoylation of serine hydroxymethyl transferase 2 with no detectable activity at other HDAC subtypes. Combination with Oxaliplatin (Cat. No. 2623) increases cytotoxicity to K562 cells; improves survival of Oxaliplatin-treated 769P cells. Cell permeable.

Technical Data

M.Wt:
366.61
Formula:
C21H38N2OS
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2374313-54-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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