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Potent, selective inhibitor of MEK1 and 2
Potent inhibitor of MEK1/2
Selective inhibitor of MEK1 and MEK2; brain penetrant
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
Selective inhibitor of MEK1/2
Selective MEK5 and ERK5 inhibitor
Potent and selective MEK inhibitor; orally bioavailable