Mouse CCL2/JE/MCP-1 DuoSet ELISA

Catalog # Availability Size / Price Qty
DY479
DY479-05
Ancillary Products Available
Mouse CCL2 / JE / MCP-1 ELISA Standard Curve
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Product Details
Procedure
Citations (154)
FAQs
Supplemental Products
Reviews (19)

Mouse CCL2/JE/MCP-1 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
3.9 - 250 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse CCL2/JE. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Scientific Data

Mouse CCL2 / JE / MCP-1 ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CCL2/JE/MCP-1

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

Entrez Gene IDs:
6347 (Human); 20296 (Mouse); 24770 (Rat); 403981 (Canine)
Alternate Names:
C-C motif chemokine ligand 2; CCL2; GDCF-2; HC11; HSMCR30; MCAF; Mcp1; MCP-1; SCYA2; SMC-CF

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Mouse CCL2/JE/MCP-1 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

154 Citations: Showing 1 - 10
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  1. Myeloid PHD2 Conditional Knockout Improves Intraplaque Angiogenesis and Vascular Remodeling in a Murine Model of Venous Bypass Grafting
    Authors: Sluiter, TJ;Tillie, RJHA;de Jong, A;de Bruijn, JBG;Peters, HAB;van de Leijgraaf, R;Halawani, R;Westmaas, M;Starink, LIW;Quax, PHA;Sluimer, JC;de Vries, MR;
    Journal of the American Heart Association
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates
  2. Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors
    Authors: Nakajima, S;Demers, G;Machuca-Parra, AI;Pour, ZD;Bairamian, D;Bouyakdan, K;Fisette, A;Kabahizi, A;Robb, J;Rodaros, D;Laurent, C;Ferreira, G;Arbour, N;Alquier, T;Fulton, S;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Cell Culture Supernates
  3. A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus
    Authors: Pereira, RDD;Rabelo, RAN;Oliveira, NFM;Porto, SLT;Andrade, ACDSP;Queiroz-Junior, CM;Barbosa, CLN;de Souza-Costa, LP;Santos, FRDS;Oliveira, FBR;da Silva, BLV;Umezu, HL;Ferreira, R;da Silva, GSF;Cruz, JS;Teixeira, MM;Costa, VV;Machado, FS;
    Viruses
    Species: Mouse
    Sample Types: Tissue Homogenates
  4. Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice
    Authors: Guo, ZF;Tongmuang, N;Li, C;Zhang, C;Hu, L;Capreri, D;Zuo, MX;Summer, R;Sun, J;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: BALF, Tissue Homogenates
  5. Xinmaikang (XMK) tablets alleviate atherosclerosis by regulating the SREBP2-mediated NLRP3/ASC/Caspase-1 signaling pathway
    Authors: Hou, C;Jiang, X;Sheng, W;Zhang, Y;Lin, Q;Hong, S;Zhao, J;Wang, T;Ye, X;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells
    Authors: Manandhar, S;Chambers, S;Miller, A;Ishii, I;Bhatia, M;
    International journal of molecular sciences
    Species: Mouse, Transgenic Mouse
    Sample Types: Tissue Homogenates
  7. Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2
    Authors: Gschwandtner, M;Gammage, AN;Deligne, C;Mies, LFM;Domaingo, A;Murdamoothoo, D;Loustau, T;Schwenzer, A;Derler, R;Carapito, R;Koch, M;M�rgelin, M;Orend, G;Kungl, AJ;Midwood, KS;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. PIMT is a novel and potent suppressor of endothelial activation
    Authors: C Zhang, ZF Guo, W Liu, K Kazama, L Hu, X Sun, L Wang, H Lee, L Lu, XF Yang, R Summer, J Sun
    Elife, 2023-04-18;12(0):.
    Species: Mouse
    Sample Types: Bronchoalveolar lavage fluid
  9. Cardiac Myocyte-Specific Overexpression of FASTKD1 Prevents Ventricular Rupture After Myocardial Infarction
    Authors: KD Marshall, PJ Klutho, L Song, R Roy, M Krenz, CP Baines
    Journal of the American Heart Association, 2023-02-15;12(4):e025867.
    Species: Mouse, Transgenic Mouse
    Sample Types: Tissue Homogenates
  10. Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
    Authors: TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin
    Cell Reports, 2022-12-30;42(1):111905.
    Species: Mouse
    Sample Types: Lavage Fluid
  11. Dysregulated systemic metabolism in a Down syndrome mouse model
    Authors: DC Sarver, C Xu, LM Velez, S Aja, AE Jaffe, MM Seldin, RH Reeves, GW Wong
    Molecular Metabolism, 2022-12-29;68(0):101666.
    Species: Mouse
    Sample Types: Serum
  12. Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
    Authors: K Chen, LY Cheong, Y Gao, Y Zhang, T Feng, Q Wang, L Jin, E Honoré, KSL Lam, W Wang, X Hui, A Xu
    Nature Communications, 2022-12-20;13(1):7838.
    Species: Mouse
    Sample Types: Serum
  13. Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells
    Authors: CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral
    Microbial pathogenesis, 2022-11-12;0(0):105881.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  14. Oral administration of human carbonic anhydrase I suppresses colitis in a murine inflammatory bowel disease model
    Authors: K Tange, S Yagi, E Takeshita, M Abe, Y Yamamoto, H Tomida, T Kawamura, M Hanayama, B Matsuura, Y Ikeda, Y Hiasa
    Scientific Reports, 2022-10-26;12(1):17983.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. The effects of intermittent hypoxia on hepatic expression of fatty acid translocase CD36 in lean and diet-induced obese mice
    Authors: Y Ji, Y Liang, PH Chu, M Ge, SC Yeung, MS Man Ip, JC Wo Mak
    Biomedical journal, 2022-10-13;0(0):.
    Species: Mouse
    Sample Types: Serum
  16. A neutrophil-B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4
    Authors: R Gawish, B Maier, G Obermayer, ML Watzenboec, AD Gorki, F Quattrone, A Farhat, K Lakovits, A Hladik, A Korosec, A Alimohamma, I Mesteri, F Oberndorfe, F Oakley, J Brain, L Boon, I Lang, CJ Binder, S Knapp
    Elife, 2022-09-30;11(0):.
    Species: Mouse
    Sample Types: Plasma
  17. Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling
    Authors: J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su
    Mediators of Inflammation, 2022-09-29;2022(0):3441357.
    Species: Mouse
    Sample Types: Cell Lysates
  18. Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
    Authors: P Boroumand, DC Prescott, T Mukherjee, PJ Bilan, M Wong, J Shen, I Tattoli, Y Zhou, A Li, T Sivasubram, N Shi, LY Zhu, Z Liu, C Robbins, DJ Philpott, SE Girardin, A Klip
    Elife, 2022-09-20;11(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice
    Authors: F Seidel, R Kleemann, W van Duyven, N van Trigt, N Keijzer, S van der Ko, C van Kooten, L Verschuren, A Menke, AJ Kiliaan, J Winter, TR Hughes, BP Morgan, F Baas, K Fluiter, MC Morrison
    International Journal of Molecular Sciences, 2022-09-14;23(18):.
    Species: Mouse
    Sample Types: Plasma
  20. Protective and vaccine dose-sparing efficacy of Poly I:C-functionalized calcium phosphate nanoparticle adjuvants in inactivated influenza vaccination
    Authors: J Lee, SY Ahn, CTT Le, DH Lee, J Jung, EJ Ko
    International immunopharmacology, 2022-09-14;112(0):109240.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  21. Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone-Pyridylhydrazone Copper(II) Complex
    Authors: XY Choo, LE McInnes, A Grubman, JM Wasielewsk, I Belaya, E Burrows, H Quek, JC Martín, S Loppi, A Sorvari, D Rait, A Powell, C Duncan, JR Liddell, H Tanila, JM Polo, T Malm, KM Kanninen, PS Donnelly, AR White
    International Journal of Molecular Sciences, 2022-09-14;23(18):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  22. Smoking status impacts treatment efficacy in smoke-induced lung inflammation: A pre-clinical study
    Authors: N Milad, M Pineault, F Tremblay, J Routhier, A Lechasseur, MJ Beaulieu, S Aubin, MC Morissette
    Frontiers in Pharmacology, 2022-09-07;13(0):971238.
    Species: Mouse
    Sample Types: BALF
  23. A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling
    Authors: SJ Matissek, M Karbalivan, W Han, A Boutilier, E Yzar-Garci, LL Kehoe, DS Gardner, A Hage, K Fleck, V Jeffers, R Rajsbaum, SF Elsawa
    Oncotarget, 2022-08-03;13(0):944-959.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  24. Evaluation and Characterization of Post-Stroke Lung Damage in a Murine Model of Cerebral Ischemia
    Authors: J Faura, L Ramiro, A Simats, F Ma, A Penalba, T Gasull, A Rosell, J Montaner, A Bustamante
    International Journal of Molecular Sciences, 2022-07-22;23(15):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  25. HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury
    Authors: PS Woods, LM Kimmig, KA Sun, AY Meliton, OR Shamaa, Y Tian, R Cetin-Atal, WW Sharp, RB Hamanaka, GM Mutlu
    Elife, 2022-07-13;11(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  26. Unravelling the sex-specific diversity and functions of adrenal gland macrophages
    Authors: B Dolfi, A Gallerand, MM Firulyova, Y Xu, J Merlin, A Dumont, A Castiglion, N Vaillant, S Quemener, H Gerke, MI Stunault, PR Schrank, SH Kim, A Zhu, J Ding, J Gilleron, V Magnone, P Barbry, D Dombrowicz, C Duranton, A Wakkach, C Blin-Wakka, B Becher, S Pagnotta, RJ Argüello, P Rantakari, S Chakarov, F Ginhoux, K Zaitsev, KW Kim, L Yvan-Charv, RR Guinamard, JW Williams, S Ivanov
    Cell Reports, 2022-06-14;39(11):110949.
    Species: Mouse
    Sample Types: Serum, Tissue Homogenates
  27. Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration
    Authors: H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield
    Oncogene, 2022-06-09;43(0):267-276.
    Species: Mouse
    Sample Types: Tissue Homogenates
  28. The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke
    Authors: S Kim, W Lee, H Jo, SK Sonn, SJ Jeong, S Seo, J Suh, J Jin, HY Kweon, TK Kim, SH Moon, S Jeon, JW Kim, YR Kim, EW Lee, HK Shin, SH Park, GT Oh
    Redox Biology, 2022-05-25;54(0):102347.
    Species: Mouse
    Sample Types: Serum
  29. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
    Authors: A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale
    Elife, 2022-04-12;11(0):.
    Species: Mouse
    Sample Types: BALF
  30. Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
    Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
    JCI Insight, 2022-02-22;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  31. CCL2-mediated monocytes regulate immune checkpoint blockade resistance in pancreatic cancer
    Authors: X Li, G He, J Liu, M Yan, M Shen, L Xu, M An, J Huang, Z Gao
    International immunopharmacology, 2022-02-17;106(0):108598.
    Species: Mouse
    Sample Types: Serum
  32. PD-L1 signaling in reactive astrocytes counteracts neuroinflammation and ameliorates neuronal damage after traumatic brain injury
    Authors: X Gao, W Li, F Syed, F Yuan, P Li, Q Yu
    Journal of Neuroinflammation, 2022-02-08;19(1):43.
    Species: Mouse
    Sample Types: Tissue Homogenates
  33. Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis
    Authors: R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler
    Biomedicines, 2022-01-07;10(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  34. The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
    Authors: KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng
    Nature Communications, 2021-11-17;12(1):6637.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  35. Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway
    Authors: YK Wu, ZN Ren, SL Zhu, YZ Wu, G Wang, H Zhang, W Chen, Z He, XL Ye, QX Zhai
    Acta pharmacologica Sinica, 2021-10-15;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  36. SYK-3BP2 pathway activity in parenchymal and myeloid cells is a key pathogenic factor in metabolic steatohepatitis
    Authors: C Luci, E Vieira, M Bourinet, D Rousseau, S Bonnafous, S Patouraux, L Lefevre, F Larbret, V Prod'homme, A Iannelli, A Tran, R Anty, B Bailly-Mai, M Deckert, P Gual
    Cellular and Molecular Gastroenterology and Hepatology, 2021-08-16;0(0):.
    Species: Mouse
    Sample Types: Serum
  37. NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
    Authors: F Guo, M Seldin, M Péterfy, S Charugundl, Z Zhou, SD Lee, A Mouton, P Rajbhandar, W Zhang, M Pellegrini, P Tontonoz, AJ Lusis, DM Shih
    Scientific Reports, 2021-08-12;11(1):16409.
    Species: Mouse
    Sample Types: Tissue Homogenates
  38. Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host
    Authors: DJ Levy, A Goundry, RSS Laires, TFR Costa, CM Novo, DJ Grab, JC Mottram, APCA Lima
    PloS Neglected Tropical Diseases, 2021-06-21;15(6):e0009526.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  39. Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
    Authors: LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller
    Nature Communications, 2021-06-10;12(1):3543.
    Species: Mouse
    Sample Types: Exosomes
  40. DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization
    Authors: L Liu, Y Wu, B Wang, Y Jiang, L Lin, X Li, S Yang
    Cell Death & Disease, 2021-05-17;12(6):500.
    Species: Mouse
    Sample Types: Serum
  41. Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice
    Authors: MTP de Oliveir, DS Coutinho, SS Guterres, AR Pohlmann, PMRE Silva, MA Martins, A Bernardi
    Pharmaceutics, 2021-05-10;13(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  42. Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPAR&gamma and NF-&kappaB Pathways in 3T3L-1 Adipocytes
    Authors: M Grancieri, HSD Martino, E Gonzalez d
    Nutrients, 2021-01-08;13(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. Respiratory Epithelial Cells Respond to Lactobacillus plantarum but Provide No Cross-Protection against Virus-Induced Inflammation
    Authors: E Mai, CM Percopo, AR Limkar, AC Sek, M Ma, HF Rosenberg
    Viruses, 2020-12-22;13(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  44. Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages
    Authors: M Song, OO Yeku, S Rafiq, T Purdon, X Dong, L Zhu, T Zhang, H Wang, Z Yu, J Mai, H Shen, B Nixon, M Li, RJ Brentjens, X Ma
    Nature Communications, 2020-12-08;11(1):6298.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  45. Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance
    Authors: A Taberner-C, Á Vinué, A Herrero-Ce, M Aguilar-Ba, JT Real, DJ Burks, S Martínez-H, H González-N
    International Journal of Molecular Sciences, 2020-12-03;21(23):.
    Species: Mouse
    Sample Types: Plasma
  46. Unique maternal immune and functional microbial profiles during prenatal stress
    Authors: AM Antonson, MV Evans, JD Galley, HJ Chen, TA Rajasekera, SM Lammers, VL Hale, MT Bailey, TL Gur
    Sci Rep, 2020-11-20;10(1):20288.
    Species: Mouse
    Sample Types: Tissue Homogenates
  47. Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration
    Authors: AS Khan, T Langmann
    J Neuroinflammation, 2020-11-03;17(1):327.
    Species: Mouse
    Sample Types: Tissue Homogenates
  48. Recombinant Myxoma Virus-Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling
    Authors: JR Yaron, L Zhang, Q Guo, EA Awo, M Burgin, LN Schutz, N Zhang, J Kilbourne, J Daggett-Vo, KM Lowe, AR Lucas
    Pharmaceutics, 2020-10-22;12(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  49. The Small RNA ErsA Plays a Role in the Regulatory Network of Pseudomonas aeruginosa Pathogenicity in Airway Infections
    Authors: S Ferrara, A Rossi, S Ranucci, I De Fino, A Bragonzi, C Cigana, G Bertoni
    mSphere, 2020-10-14;5(5):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  50. Mental stress promotes the proliferation of endometriotic lesions in mice
    Authors: T Kawakita, T Kato, T Iwasa, O Erdenebaya, Y Kadota, K Kasai, K Yoshida, M Irahara
    Cytokine, 2020-08-06;135(0):155222.
    Species: Mouse
    Sample Types: Plasma
  51. Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case
    Authors: S Abouelasra, M De Bondt, N Berghmans, M Gouwy, VLS de Oliveir, SC Oliveira, FA Amaral, P Proost, J Van Damme, S Struyf, M De Buck
    Mediators Inflamm., 2020-07-06;2020(0):6087109.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  52. Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice
    Authors: A Jarneborn, M Mohammad, C Engdahl, Z Hu, M Na, A Ali, T Jin
    Sci Rep, 2020-07-02;10(1):10891.
    Species: Mouse
    Sample Types: Serum
  53. Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury
    Authors: D Kempuraj, ME Ahmed, GP Selvakumar, R Thangavel, SP Raikwar, SA Zaheer, SS Iyer, C Burton, D James, A Zaheer
    Mediators Inflamm., 2020-06-24;2020(0):4243953.
    Species: Mouse
    Sample Types: Tissue Homogenates
  54. The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye
    Authors: A Wolf, M Herb, M Schramm, T Langmann
    Nat Commun, 2020-06-01;11(1):2709.
    Species: Mouse
    Sample Types: Tissue Homogenates
  55. The role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis
    Authors: M Mohammad, Z Hu, A Ali, PK Kopparapu, M Na, A Jarneborn, MDN Stroparo, MT Nguyen, A Karlsson, F Götz, R Pullerits, T Jin
    Sci Rep, 2020-05-13;10(1):7936.
    Species: Mouse
    Sample Types: Serum
  56. Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response
    Authors: M Rahabi, G Jacquemin, M Prat, E Meunier, M AlaEddine, B Bertrand, L Lefèvre, K Benmoussa, P Batigne, A Aubouy, J Auwerx, S Kirzin, D Bonnet, M Danjoux, B Pipy, L Alric, H Authier, A Coste
    Cell Rep, 2020-03-31;30(13):4386-4398.e5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection
    Authors: V Garcia-Cas, G Marcial, L Albarracín, M Tomokiyo, P Clua, H Takahashi, H Kitazawa, A Garcia-Can, J Villena
    Microorganisms, 2020-03-27;8(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  58. Interleukin-1 Receptor-Induced Nitric Oxide Production in the Pancreas Controls Hyperglycemia Caused by Scorpion Envenomation
    Authors: MB Reis, J Elias-Oliv, MR Pastore, SG Ramos, LG Gardinassi, LH Faccioli
    Toxins (Basel), 2020-03-05;12(3):.
    Species: Mouse
    Sample Types: Serum
  59. Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity
    Authors: RDC da Cunha d, MM Cruz, TM de Farias, VS da Silva, J de Jesus S, MM Telles, MIC Alonso-Val
    Physiol Rep, 2020-02-01;8(4):e14380.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  60. The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity
    Authors: Y Lu, J Ma, J Zhao, Z Song, C Zhou, X Liu, W Teng, W Wang, Q Zhang, W Yan, P Jiao
    Obes Facts, 2020-01-21;0(0):1-16.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  61. Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo
    Authors: O Danov, L Lasswitz, H Obernolte, C Hesse, A Braun, S Wronski, K Sewald
    Respir. Res., 2019-10-22;20(1):228.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
    Authors: SS Welc, I Flores, M Wehling-He, J Ramos, Y Wang, C Bertoni, JG Tidball
    Nat Commun, 2019-06-26;10(1):2788.
    Species: Mouse, Transgenic Mouse
    Sample Types: Cell Culture Supernates
  63. Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis
    Authors: BE Hsu, S Tabariès, RM Johnson, S Andrzejews, J Senecal, C Lehuédé, MG Annis, EH Ma, S Völs, L Ramsay, R Froment, A Monast, IR Watson, Z Granot, RG Jones, J St-Pierre, PM Siegel
    Cell Rep, 2019-06-25;27(13):3902-3915.e6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  64. The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus
    Authors: M Mohammad, MT Nguyen, C Engdahl, M Na, A Jarneborn, Z Hu, A Karlsson, R Pullerits, A Ali, F Götz, T Jin
    PLoS Pathog., 2019-06-21;15(6):e1007877.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy
    Authors: M Pascual-Ga, E Bonfill-Te, E Planas-Rig, C Rubio-Pere, R Iurlaro, A Arias, I Cuartas, A Sala-Hojma, L Escudero, F Martínez-R, I Huber-Ruan, P Nuciforo, L Pedrosa, C Marques, I Braña, E Garralda, M Vieito, M Squatrito, E Pineda, F Graus, C Espejo, J Sahuquillo, J Tabernero, J Seoane
    Nat Commun, 2019-06-11;10(1):2416.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  66. Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma
    Authors: V Maximov, Z Chen, Y Wei, MH Robinson, CJ Herting, NS Shanmugam, VA Rudneva, KC Goldsmith, TJ MacDonald, PA Northcott, D Hambardzum, AM Kenney
    Nat Commun, 2019-06-03;10(1):2410.
    Species: Mouse
    Sample Types: Tissue Homogenates
  67. In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
    Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
    EBioMedicine, 2019-05-23;0(0):.
    Species: Mouse
    Sample Types: Plasma
  68. Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice
    Authors: M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow
    J Neuroinflammation, 2019-04-02;16(1):69.
    Species: Mouse
    Sample Types: Tissue Homogenates
  69. NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin
    Authors: AML Scantleber, M Uil, LM Butter, R Poelman, N Claessen, SE Girardin, S Florquin, JJTH Roelofs, JC Leemans
    PLoS ONE, 2019-03-25;14(3):e0214437.
    Species: Mouse
    Sample Types: Tissue Homogenates
  70. EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke
    Authors: AS Ernst, LI Böhler, AM Hagenston, A Hoffmann, S Heiland, C Sticht, M Bendszus, M Hecker, H Bading, HH Marti, T Korff, R Kunze
    Acta Neuropathol Commun, 2019-02-05;7(1):15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  71. Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
    Authors: Y Pan, X Hui, RLC Hoo, D Ye, CYC Chan, T Feng, Y Wang, KSL Lam, A Xu
    J. Clin. Invest., 2019-01-22;129(2):834-849.
    Species: Mouse
    Sample Types: Serum
  72. Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
    Authors: CC Campa, RL Silva, JP Margaria, T Pirali, MS Mattos, LR Kraemer, DC Reis, G Grosa, F Copperi, EM Dalmarco, RCP Lima-Júnio, S Aprile, V Sala, F Dal Bello, DS Prado, JC Alves-Filh, C Medana, GD Cassali, GC Tron, MM Teixeira, E Ciraolo, RC Russo, E Hirsch
    Nat Commun, 2018-12-12;9(1):5232.
    Species: Mouse
    Sample Types:
  73. CCR2 mediates increased susceptibility to post-H1N1 bacterial pneumonia by limiting dendritic cell induction of IL-17
    Authors: SJ Gurczynski, N Nathani, HI Warheit-Ni, EM Hult, A Podsiad, J Deng, RL Zemans, U Bhan, BB Moore
    Mucosal Immunol, 2018-11-29;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  74. Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma
    Authors: GM Wiedemann, C Aithal, A Kraechan, C Heise, BL Cadilha, J Zhang, P Duewell, R Ballotti, S Endres, C Bertolotto, S Kobold
    Transl Oncol, 2018-11-28;12(2):350-360.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice
    Authors: M Talbot, M Hamel-Auge, MJ Beaulieu, M Gazzola, A Lechasseur, S Aubin, MÈ Paré, D Marsolais, Y Bossé, MC Morissette
    Respir. Res., 2018-07-03;19(1):131.
    Species: Mouse
    Sample Types: BALF
  76. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms
    Authors: DT Skelly, ÉW Griffin, CL Murray, S Harney, C O'Boyle, E Hennessy, MA Dansereau, A Nazmi, L Tortorelli, JN Rawlins, DM Bannerman, C Cunningham
    Mol. Psychiatry, 2018-06-06;24(10):1533-1548.
    Species: Mouse
    Sample Types: Plasma
  77. Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking
    Authors: A Porrello, PL Leslie, EB Harrison, BK Gorentla, S Kattula, SK Ghosh, SH Azam, A Holtzhause, YL Chao, MC Hayward, TA Waugh, S Bae, V Godfrey, SH Randell, C Oderup, L Makowski, J Weiss, MD Wilkerson, DN Hayes, HS Earp, AS Baldwin, AS Wolberg, CV Pecot
    Nat Commun, 2018-05-18;9(1):1988.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  78. Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy
    Authors: KJ Katschke, H Xi, C Cox, T Truong, Y Malato, WP Lee, B McKenzie, R Arceo, J Tao, L Rangell, M Reichelt, L Diehl, J Elstrott, RM Weimer, MVL Campagne
    Sci Rep, 2018-05-09;8(1):7348.
    Species: Mouse
    Sample Types: Tissue Homogenates
  79. Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction ininduced arthritis
    Authors: B Bergmann, P Jirholt, P Henning, C Lindholm, C Ohlsson, IB McInnes, UH Lerner, I Gjertsson
    Infect. Immun., 2018-04-23;0(0):.
    Species: Mouse
    Sample Types: Serum
  80. Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
    Authors: F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti
    Glia, 2018-04-17;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  81. Alternaria alternata challenge at the nasal mucosa results in eosinophilic inflammation and increased susceptibility to influenza virus infection
    Authors: M Ma, JL Redes, CM Percopo, KM Druey, HF Rosenberg
    Clin. Exp. Allergy, 2018-04-15;0(0):.
    Species: Mouse
    Sample Types: Nasal Lavage Fluid
  82. Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema
    Authors: IK Sundar, K Rashid, J Gerloff, J Rangel-Mor, D Li, I Rahman
    FASEB J., 2018-04-09;0(0):fj201701518R.
    Species: Mouse
    Sample Types: Tissue Homogenates
  83. p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
    Authors: A Sagiv, A Bar-Shai, N Levi, M Hatzav, L Zada, Y Ovadya, L Roitman, G Manella, O Regev, J Majewska, E Vadai, R Eilam, SW Feigelson, M Tsoory, M Tauc, R Alon, V Krizhanovs
    Cell Rep, 2018-03-27;22(13):3468-3479.
    Species: Mouse
    Sample Types: BALF
  84. Identification of periplakin as a major regulator of lung injury and repair in mice
    Authors: V Besnard, R Dagher, T Madjer, A Joannes, M Jaillet, M Kolb, P Bonniaud, LA Murray, MA Sleeman, B Crestani
    JCI Insight, 2018-03-08;3(5):.
    Species: Mouse
    Sample Types: BALF
  85. The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair
    Authors: D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi
    Front Immunol, 2018-03-05;9(0):417.
    Species: Mouse
    Sample Types: Serum
  86. FOXO3-dependent apoptosis limits alcohol-induced liver inflammation by promoting infiltrating macrophage differentiation
    Authors: Z Li, J Zhao, S Zhang, SA Weinman
    Cell Death Discov, 2018-02-13;4(0):16.
    Species: Mouse
    Sample Types: Serum
  87. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection
    Authors: EE Hornick, B Banoth, AM Miller, ZR Zacharias, N Jain, ME Wilson, KN Gibson-Cor, KL Legge, GA Bishop, FS Sutterwala, SL Cassel
    J. Immunol., 2017-12-27;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  88. Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration
    Authors: L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai
    J. Biol. Chem., 2017-06-27;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  89. NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity
    Authors: G Stokman, L Kors, PJ Bakker, E Rampanelli, N Claessen, GJD Teske, L Butter, H van Andel, MA van den Be, PWB Larsen, MC Dessing, CJ Zuurbier, SE Girardin, S Florquin, JC Leemans
    J. Exp. Med., 2017-06-16;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  90. The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype
    Authors: Á Vinué, J Navarro, A Herrero-Ce, M García-Cub, I Andrés-Bla, S Martínez-H, JT Real, JF Ascaso, H González-N
    Diabetologia, 2017-06-12;0(0):.
    Species: Mouse
    Sample Types: Plasma
  91. Fetuin-A aggravates lipotoxicity in podocytes via interleukin-1 signaling
    Authors: JM Orellana, K Kampe, F Schulze, J Sieber, AW Jehle
    Physiol Rep, 2017-05-01;5(10):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  92. Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection
    Authors: CT Molloy, JS Andonian, HM Seltzer, MC Procario, ME Watson, JB Weinberg
    Virology, 2017-04-11;507(0):64-74.
    Species: Mouse
    Sample Types: BALF
  93. Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
    Authors: M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher
    BMC Evol. Biol, 2017-03-23;17(1):90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  94. Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants
    Authors: LT Hsieh, MV Nastase, H Roedig, J Zeng-Brouw, C Poluzzi, S Schwalm, C Fork, C Tredup, RP Brandes, M Wygrecka, A Huwiler, J Pfeilschif, L Schaefer
    Int J Mol Sci, 2017-03-09;18(3):.
    Species: Mouse
    Sample Types: Plasma
  95. Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice
    Authors: M Na, W Wang, Y Fei, E Josefsson, A Ali, T Jin
    PLoS ONE, 2017-03-06;12(3):e0173492.
    Species: Mouse
    Sample Types: Tissue Homogenates
  96. Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection
    Authors: A Kawaguchi, T Suzuki, Y Ohara, K Takahashi, Y Sato, A Ainai, N Nagata, M Tashiro, H Hasegawa
    PLoS ONE, 2017-02-28;12(2):e0173008.
    Species: Mouse
    Sample Types: BALF
  97. Antibodies against nonstructural protein 1 protect mice from dengue virus-induced mast cell activation
    Authors: YT Chu, SW Wan, YC Chang, CK Lee, BA Wu-Hsieh, R Anderson, YS Lin
    Lab. Invest, 2017-02-27;0(0):.
    Species: Mouse
    Sample Types: Serum
  98. The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
    Authors: T Hartwig, A Montinaro, S von Karste, A Sevko, S Surinova, A Chakravart, L Taraborrel, P Draber, E Lafont, F Arce Varga, MA El-Bahrawy, SA Quezada, H Walczak
    Mol. Cell, 2017-02-16;65(4):730-742.e5.
    Species: Mouse
    Sample Types: Tissue Homogenates
  99. APPL1 prevents pancreatic beta cell death and inflammation by dampening NF?B activation in a mouse model of type 1 diabetes
    Authors: Xue Jiang
    Diabetologia, 2016-12-23;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  100. NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis
    Authors: Andrey Lozhkin
    J. Mol. Cell. Cardiol, 2016-12-14;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  101. PGI2 Controls Pulmonary NK Cells That Prevent Airway Sensitization to House Dust Mite Allergen
    Authors: Bryan Simons
    J. Immunol, 2016-11-28;0(0):.
    Species: Mouse
    Sample Types: BALF
  102. Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
    Authors: Sundar, Isaac K, Ahmad, Tanveer, Yao, Hongwei, Hwang, Jae-woon, Gerloff, Janice, Lawrence, B Paige, Sellix, Michael, Rahman, Irfan
    Sci Rep, 2015-04-29;4(0):9927.
    Species: Mouse
    Sample Types: BALF
  103. Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.
    Authors: Goritzka M, Makris S, Kausar F, Durant L, Pereira C, Kumagai Y, Culley F, Mack M, Akira S, Johansson C
    J Exp Med, 2015-04-20;212(5):699-714.
    Species: Mouse
    Sample Types: Tissue Homogenates
  104. Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.
    Authors: Dau T, Sarker R, Yildirim A, Eickelberg O, Jenne D
    Nat Commun, 2015-04-10;6(0):6722.
    Species: Mouse
    Sample Types: BALF
  105. IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages.
    Authors: Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y
    J Immunol, 2015-02-27;194(7):3156-68.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  106. Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis.
    Authors: Larson-Casey J, Murthy S, Ryan A, Carter A
    J Biol Chem, 2014-11-05;289(52):36204-19.
    Species: Mouse
    Sample Types: BALF
  107. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
    Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
    Nature, 2014-10-22;515(7525):130-3.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  108. No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
    Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
    PLoS ONE, 2014-09-09;9(9):e106420.
    Species: Mouse
    Sample Types: Serum
  109. Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.
    Authors: Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, Oldstone M
    J Virol, 2014-03-26;88(11):6281-93.
    Species: Mouse
    Sample Types: BALF
  110. Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice.
    Authors: Liu, Xianglan, McMurphy, Travis, Xiao, Run, Slater, Andrew, Huang, Wei, Cao, Lei
    Mol Ther, 2014-03-18;22(7):1275-84.
    Species: Mouse
    Sample Types: Serum
  111. The role of Nox2-derived ROS in the development of cognitive impairment after sepsis.
    Authors: Hernandes M, D'Avila J, Trevelin S, Reis P, Kinjo E, Lopes L, Castro-Faria-Neto H, Cunha F, Britto L, Bozza F
    J Neuroinflammation, 2014-02-27;11(0):36.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  112. Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection.
    Authors: Teijaro J, Walsh K, Rice S, Rosen H, Oldstone M
    Proc Natl Acad Sci U S A, 2014-02-26;111(10):3799-804.
    Species: Mouse
    Sample Types: BALF
  113. A TNF-alpha-CCL20-CCR6 axis regulates Nod1-induced B cell responses.
    Authors: Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, McCarthy D, Yu M, Summers deLuca L, Ward L, Waldron J, Philpott D, Gommerman J, Fritz J
    J Immunol, 2014-02-17;192(6):2787-99.
    Species: Mouse
    Sample Types: Serum
  114. Bone marrow-specific knock-in of a non-activatable Ikkalpha kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.
    Authors: Tilstam P, Gijbels M, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Doring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen R, de Winther M, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H
    PLoS ONE, 2014-02-03;9(2):e87452.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  115. MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung.
    Authors: Malmhall C, Alawieh S, Lu Y, Sjostrand M, Bossios A, Eldh M, Radinger M
    J Allergy Clin Immunol, 2013-12-24;133(5):1429-38, 1438.
    Species: Mouse
    Sample Types: Tissue Homogenates
  116. Munc18-2 and syntaxin 3 control distinct essential steps in mast cell degranulation.
    Authors: Brochetta C, Suzuki R, Vita F, Soranzo M, Claver J, Madjene L, Attout T, Vitte J, Varin-Blank N, Zabucchi G, Rivera J, Blank U
    J Immunol, 2013-12-09;192(1):41-51.
    Species: Rat
    Sample Types: Cell Culture Supernates
  117. Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
    Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
    PLoS ONE, 2013-11-21;8(11):e80723.
    Species: Mouse
    Sample Types: BALF
  118. A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
    Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
    Diabetes, 2013-11-05;63(3):850-66.
    Species: Mouse
    Sample Types: Plasma
  119. Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.
    Authors: Hwang J, Sundar I, Yao H, Sellix M, Rahman I
    FASEB J, 2013-09-11;28(1):176-94.
    Species: Mouse
    Sample Types: Tissue Homogenates
  120. Deficiency of C5L2 increases macrophage infiltration and alters adipose tissue function in mice.
    Authors: Gauvreau D, Gupta A, Fisette A, Tom F, Cianflone K
    PLoS ONE, 2013-04-22;8(4):e60795.
    Species: Mouse
    Sample Types: Plasma
  121. A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
    Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
    EMBO Mol Med, 2013-04-01;5(4):516-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  122. Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
    Authors: Wu Z, MacNeil A, Berman J, Lin T
    PLoS ONE, 2013-03-06;8(3):e58560.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  123. The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice.
    Authors: Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I
    PLoS ONE, 2013-02-13;8(2):e56866.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions.
    Authors: Miegueu P, Cianflone K, Richard D, St-Pierre D
    Int J Obes (Lond), 2012-05-08;37(3):366-74.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
    Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
    Infect. Immun., 2011-10-24;80(1):100-9.
    Species: Mouse
    Sample Types: Serum
  126. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
    Authors: Walsh KB, Teijaro JR, Wilker PR
    Proc. Natl. Acad. Sci. U.S.A., 2011-06-29;108(29):12018-23.
    Species: Mouse
    Sample Types: BALF
  127. Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
    Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
    Am. J. Pathol., 2011-05-05;179(1):125-33.
    Species: Mouse
    Sample Types: BALF
  128. The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
    Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
    J. Immunol., 2011-03-25;186(9):5425-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  129. Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
    Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
    J. Leukoc. Biol., 2010-11-02;89(2):269-82.
    Species: Mouse
    Sample Types: Tissue Homogenates
  130. Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
    Authors: van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J
    J. Neurochem., 2010-06-16;114(5):1511-26.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  131. Latent herpesvirus infection augments experimental pulmonary fibrosis.
    Authors: Vannella KM, Luckhardt TR, Wilke CA, van Dyk LF, Toews GB, Moore BB
    Am. J. Respir. Crit. Care Med., 2009-12-10;181(5):465-77.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
    Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
    J. Immunol., 2009-07-27;183(4):2642-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  133. Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
    Authors: Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400.
    Species: Mouse
    Sample Types: BALF
  134. Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia.
    Authors: Lukkarinen H, Hogmalm A, Lappalainen U, Bry K
    Am. J. Respir. Cell Mol. Biol., 2008-12-18;41(1):59-68.
    Species: Mouse
    Sample Types: Tissue Homogenates
  135. Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease.
    Authors: Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT
    J. Virol., 2008-11-05;83(2):522-39.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
    Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
    Atherosclerosis, 2008-09-02;204(1):147-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  137. Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways.
    Authors: Sun J, Ramnath RD, Tamizhselvi R, Bhatia M
    Am. J. Physiol., Cell Physiol., 2008-07-02;295(3):C679-91.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
    Authors: Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME
    Proc. Natl. Acad. Sci. U.S.A., 2008-05-14;105(20):7240-5.
    Species: Mouse
    Sample Types: BALF
  139. Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
    Authors: Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y
    J. Neurosci., 2008-03-26;28(13):3277-90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. Surfactant protein D alters allergic lung responses in mice and human subjects.
    Authors: Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME
    J. Allergy Clin. Immunol., 2008-03-19;121(5):1140-1147.e2.
    Species: Mouse
    Sample Types: BALF
  141. Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues.
    Authors: Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM
    Blood, 2008-03-17;112(2):256-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  142. Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection.
    Authors: Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC
    J. Immunol., 2008-01-15;180(2):1080-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  143. Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes.
    Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE
    J. Immunol., 2007-12-15;179(12):8381-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  144. Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production.
    Authors: Wang KX, Shi Y, Denhardt DT
    Proc. Natl. Acad. Sci. U.S.A., 2007-09-04;104(37):14777-82.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice.
    Authors: Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, Shapiro SD
    J. Immunol., 2007-06-15;178(12):8090-6.
    Species: Mouse
    Sample Types: BALF
  146. Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
    Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
    J. Leukoc. Biol., 2007-06-12;82(3):678-85.
    Species: Mouse
    Sample Types: Plasma
  147. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007-04-12;26(4):445-59.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  148. Infiltrating neutrophils induce allospecific CTL in response to immunization with apoptotic cells via MCP-1 production.
    Authors: Shiratsuchi Y, Iyoda T, Tanimoto N, Kegai D, Nagata K, Kobayashi Y
    J. Leukoc. Biol., 2006-11-09;81(2):412-20.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  149. A functional comparison of canine and murine bone marrow derived cultured mast cells.
    Authors: Lin TY, London CA
    Vet. Immunol. Immunopathol., 2006-10-06;114(3):320-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  150. Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis.
    Authors: Gomes RN, Bozza FA, Amancio RT, Japiassu AM, Vianna RC, Larangeira AP, Gouvea JM, Bastos MS, Zimmerman GA, Stafforini DM, Prescott SM, Bozza PT, Castro-Faria-Neto HC
    Shock, 2006-07-01;26(1):41-9.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  151. Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
    Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
    Eur. J. Immunol., 2006-05-01;36(5):1145-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  152. Increased pulmonary responses to acute ozone exposure in obese db/db mice.
    Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
    Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L856-65.
    Species: Mouse
    Sample Types: Serum
  153. Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
    Authors: Carpenter KJ, Hogaboam CM
    Infect. Immun., 2005-11-01;73(11):7198-207.
    Species: Mouse
    Sample Types: Tissue Homogenates
  154. Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1.
    Authors: Barcelos LS, Talvani A, Teixeira AS, Vieira LQ, Cassali GD, Andrade SP, Teixeira MM
    J. Leukoc. Biol., 2005-05-13;78(2):352-8.
    Species: Mouse
    Sample Types: Complex Sample Type

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Reviews for Mouse CCL2/JE/MCP-1 DuoSet ELISA

Average Rating: 4.6 (Based on 19 Reviews)

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Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 10/05/2023
Sample Tested: Peritoneal macrophages

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 09/11/2023
Sample Tested: Colon tissue

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 05/19/2023
Sample Tested: Colon tissue

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 11/07/2022
Sample Tested: Cell culture supernatant

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 06/09/2022
Sample Tested: Colon tissue

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 04/13/2022
Sample Tested: Cell culture supernatant

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 03/11/2022
Sample Tested: Serum and Plasma

Used this kit for quantifying mouse MCP-1 in serum samples, could see the detection but not strong in our samples. Standard curve looks good.


Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 01/19/2022
Sample Tested: Colon tissue,Serum

stable and precise


Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 12/21/2021
Sample Tested: mouse cell line conditioned media

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 04/02/2020
Sample Tested: Serum and Plasma

We used this kit for the quantification of CCL2 in human serum and plasma. Works very well and well-described protocol.


Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 09/03/2019
Sample Tested: Blood monocytes,Monocytes,mouse BAL

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Ivan Luzardo on 12/11/2018
Sample Tested: Serum and Plasma

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Denis Streltsov on 11/21/2018
Sample Tested: peritoneal fluid,Plasma

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 07/13/2018
Sample Tested: Brain tissue

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 05/04/2018
Sample Tested: Breast cancer cells

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 04/26/2018
Sample Tested: Pancreatic cancer cells

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Adam Guess on 10/19/2017
Sample Tested: Cell Culture Supernates

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 10/06/2016
Sample Tested: Cell culture supernatant

Mouse CCL2/JE/MCP-1 DuoSet ELISA
By Anonymous on 07/06/2016
Sample Tested: Mouse BAL fluid