Sort by:
Selective, high affinity Bcl-2 inhibitor; orally bioavailable
Glucocorticoid receptor agonist
High affinity and selective activator of Bax
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
Allosteric inhibitor of Bax channel activation
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation
Inhibits Mcl-1-BIM interaction
Bcl-6 inhibitor; 10-fold more potent than endogenous Bcl-6 corepressors
Inhibitor of Bcl-2 family members; antiapoptotic
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
Molecular glue; induces degradation of BCL6