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PlGF: Products
PlGF (placenta growth factor) is secreted primarily by villous trophoblasts and decidual cells, with circulating levels increasing during pregnancy but attenuated in preeclampsia. PlGF signals through VEGF R1/Flt‑1 and Neuropilins, while VEGF binds both VEGF R1 and R2 but signals mainly through VEGF R2.
PlGF reduces binding of VEGF to VEGF R1 and increases VEGF/VEGF R2‑mediated angiogenesis. It induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing and also contribute to inflammation in active sickle cell disease and atherosclerosis.
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"PlGF" has 22 results in Products.
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Simple Plex Human PlGF Cartridge
Simple Plex Human PIGF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Proteome Profiler Human Angiogenesis Array Kit
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Custom Simple Plex™ Assay Panels
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
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