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Thrombopoietin/Tpo: Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
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"Thrombopoietin/Tpo" has 28 results in Products.
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Proteome Profiler Mouse XL Cytokine Array
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Human Cytokine A Premixed Magnetic Luminex® Performance Assay
Build your own Human Cytokine Premixed Luminex Performance Assay using our custom ordering tool. Earn double rewards for reviews
Recombinant Human Thrombopoietin His (HEK-293) Protein, CF
Analyzed by SEC-MALS. His-tag (HEK-293-expressed)
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