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Cdk inhibitor; potently inhibits cdk1 and cdk2; also inhibits CK1; acts as molecular glue
Molecular glue; pre-mRNA splicing modulator
Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone
α2 integrin inhibitor; anti-angiogenic
Molecular glue Degrader; induces ubiquitination and degradation of cyclin K
Molecular glue; induces degradation of CCNK and CDK12
Molecular glue; induces degradation of GSPT1/2
Molecular glue; induces degradation of BCL6
Molecular glue; induces degradation of NQAT1
Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
Molecular glue Degrader of mutant β-catenin
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
STING agonist, molecular glue that causes oligomerization of STING
Potent molecular glue Degrader of BET proteins BRD4 and BRD2
Potent and selective CK1α molecular glue Degrader