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Non-selective protein kinase inhibitor
Alkylating agent; chemotherapeutic
Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation
Synthetic thymidine analog; used for cell proliferation assays
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
DNA topoisomerase I inhibitor; Camptothecin (Cat. No. 1100) analog
Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
Reagent for RNA SHAPE-MaP chemistry
Molecular glue; pre-mRNA splicing modulator
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
Selective orthosteric inhibitor of the BRCA2-RAD51 interaction
Hypoxia-activated DNA alkylating agent prodrug
Cytostatic agent; exhibits DNA alkylating and purine analog properties
Potent and selective DYRK1A inhibitor
HIV RNA splicing modulator
RNA conformation probe; reagent for COMRADES RNA platform
Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3
Uridine analog, used for labeling RNA synthesis
Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry
Potent and selective herpes simplex virus (HSV) helicase primase inhibitor
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
IKBKAP pre-mRNA splicing modulator
Bivalent SHAPE cross-linking reagent
SHAPE-JuMP monoadduct control for TBIA (Cat. No. 7788)
Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
Selective SMN2 gene splicing modifier
Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments
Reagent for RNA SHAPE-MaP experiments in live cells
Potent HTT pre-RNA splicing modulator
Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells